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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2003 5
2004 4
2005 2
2006 7
2007 10
2008 12
2009 8
2010 9
2011 11
2012 7
2013 8
2014 9
2015 5
2016 7
2017 6
2018 4
2019 2
2020 0
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92 results
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Prostaglandin E2-EP2-NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms.
Aoki T, Frȍsen J, Fukuda M, Bando K, Shioi G, Tsuji K, Ollikainen E, Nozaki K, Laakkonen J, Narumiya S. Aoki T, et al. Sci Signal. 2017 Feb 7;10(465):eaah6037. doi: 10.1126/scisignal.aah6037. Sci Signal. 2017. PMID: 28174280
We correlated EP2 and cyclooxygenase-2 (COX-2) with macrophage infiltration in human intracranial aneurysm lesions. Monitoring the spatiotemporal pattern of NF-κB activation during intracranial aneurysm development in mice showed that NF-κB was first a …
We correlated EP2 and cyclooxygenase-2 (COX-2) with macrophage infiltration in human intracranial aneurysm lesio …
Butyrate mediated regulation of RNA binding proteins in the post-transcriptional regulation of inflammatory gene expression.
Torun A, Enayat S, Sheraj I, Tunçer S, Ülgen DH, Banerjee S. Torun A, et al. Cell Signal. 2019 Dec;64:109410. doi: 10.1016/j.cellsig.2019.109410. Epub 2019 Sep 2. Cell Signal. 2019. PMID: 31487531
Short chain fatty acids (SCFAs) are produced by commensal bacteria in the gut and are known to reduce inflammation through transcriptional inhibition of cytokines and inflammatory proteins such as cyclooxygenase-2 (COX-2). ...As a proof of concept, we show bu …
Short chain fatty acids (SCFAs) are produced by commensal bacteria in the gut and are known to reduce inflammation through transcriptional i …
Leucine-rich repeat kinase 2 modulates cyclooxygenase 2 and the inflammatory response in idiopathic and genetic Parkinson's disease.
Lopez de Maturana R, Aguila JC, Sousa A, Vazquez N, Del Rio P, Aiastui A, Gorostidi A, Lopez de Munain A, Sanchez-Pernaute R. Lopez de Maturana R, et al. Neurobiol Aging. 2014 May;35(5):1116-24. doi: 10.1016/j.neurobiolaging.2013.11.018. Epub 2013 Nov 22. Neurobiol Aging. 2014. PMID: 24360742
Basal cyclooxygenase (COX)-2 RNA levels were very high in the fibroblasts of all patients. Remarkably, LRRK2 silencing experiments significantly reduced basal COX-2 levels and COX-2 induction after a pro-inflammatory stimulus. Additionall …
Basal cyclooxygenase (COX)-2 RNA levels were very high in the fibroblasts of all patients. Remarkably, LRRK2 silencing experim …
Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1).
Sully G, Dean JL, Wait R, Rawlinson L, Santalucia T, Saklatvala J, Clark AR. Sully G, et al. Biochem J. 2004 Feb 1;377(Pt 3):629-39. doi: 10.1042/BJ20031484. Biochem J. 2004. PMID: 14594446 Free PMC article.
COX-2 (cyclo-oxygenase-2) mRNA is degraded rapidly in resting cells, but is stabilized by the mitogen-activated protein kinase p38 signalling pathway in response to pro-inflammatory stimuli. ...CR1 was shown to bind AUF-1 [ARE/poly(U)-binding/degradation fact
COX-2 (cyclo-oxygenase-2) mRNA is degraded rapidly in resting cells, but is stabilized by the mitogen-activated protein
Association between expression of embryonic lethal abnormal vision-like protein HuR and cyclooxygenase-2 in oral squamous cell carcinoma.
Cha JD, Li S, Cha IH. Cha JD, et al. Head Neck. 2011 May;33(5):627-37. doi: 10.1002/hed.21507. Epub 2010 Oct 19. Head Neck. 2011. PMID: 20960565
METHODS: To assess the correlation between COX-2 and HuR in oral squamous cell carcinoma (OSCC), the expression patterns of HuR and COX-2 were assessed via immunohistochemistry analyses of 103 OSCC samples. ...CONCLUSION: Our results indi …
METHODS: To assess the correlation between COX-2 and HuR in oral squamous cell carcinoma (OSCC), the expression pattern …
HuR translocation to the cytoplasm of cancer cells in actin-independent manner.
Habiba U, Kuroshima T, Yanagawa-Matsuda A, Kitamura T, Chowdhury A, Jehung JP, Hossain E, Sano H, Kitagawa Y, Shindoh M, Higashino F. Habiba U, et al. Exp Cell Res. 2018 Aug 15;369(2):218-225. doi: 10.1016/j.yexcr.2018.05.021. Epub 2018 May 26. Exp Cell Res. 2018. PMID: 29807023 Free article.
Human antigen R (HuR) is a RNA-binding protein, which binds to the AU-rich element (ARE) in the 3'-untranslated region (3'-UTR) of certain mRNA and is involved in the export and stabilization of ARE-mRNA. HuR constitutively relocates to the cyto
Human antigen R (HuR) is a RNA-binding protein, which binds to the AU-rich element (ARE) in the 3'-untranslated
Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression.
Denkert C, Weichert W, Pest S, Koch I, Licht D, Köbel M, Reles A, Sehouli J, Dietel M, Hauptmann S. Denkert C, et al. Cancer Res. 2004 Jan 1;64(1):189-95. doi: 10.1158/0008-5472.can-03-1987. Cancer Res. 2004. PMID: 14729623 Free article.
The human embryonic-lethal abnormal vision-like protein HuR is involved in the regulation of mRNA turnover and serves as a shuttling protein between the nucleus and the cytoplasm that stabilizes mRNAs containing adenine- and uridin …
The human embryonic-lethal abnormal vision-like protein HuR is involved in the regulation o …
Expression of embryonic lethal abnormal vision (ELAV)-like protein HuR and cyclooxygenase-2 (COX-2) in Ewing sarcoma.
Do SI, Araujo ES, Kalil RK, Bacchini P, Bertoni F, Unni KK, Park YK. Do SI, et al. Tumori. 2008 May-Jun;94(3):347-50. Tumori. 2008. PMID: 18705402
AIMS AND BACKGROUND: HuR is a member of the family of ELAV (embryonic lethal abnormal vision)-like proteins that stabilize several cellular mRNAs by binding to AU-rich elements in the 3' untranslated region of the mRNA. Cyclooxygenase- …
AIMS AND BACKGROUND: HuR is a member of the family of ELAV (embryonic lethal abnormal vision)-like
Expression of the embryonic lethal abnormal vision-like protein HuR in human mesothelioma: association with cyclooxygenase-2 and prognosis.
Stoppoloni D, Cardillo I, Verdina A, Vincenzi B, Menegozzo S, Santini M, Sacchi A, Baldi A, Galati R. Stoppoloni D, et al. Cancer. 2008 Nov 15;113(10):2761-9. doi: 10.1002/cncr.23904. Cancer. 2008. PMID: 18831511 Free article.
BACKGROUND: The human embryonic lethal abnormal vision (ELAV)-like protein HuR is a messenger RNA (mRNA)-binding protein that controls the stability of certain transcripts, including cyclooxygenase2 (COX-2). METHODS: …
BACKGROUND: The human embryonic lethal abnormal vision (ELAV)-like protein HuR is a messeng …
Elevated Hu-Antigen Receptor (HuR) Expression is Associated with Tumor Aggressiveness and Poor Prognosis but not with COX-2 Expression in Invasive Breast Carcinoma Patients.
Giaginis C, Sampani A, Kotta-Loizou I, Giannopoulou I, Danas E, Politi E, Tsourouflis G, Kouraklis G, Patsouris E, Keramopoulos A, Nakopoulou L, Theocharis S. Giaginis C, et al. Pathol Oncol Res. 2018 Jul;24(3):631-640. doi: 10.1007/s12253-017-0288-1. Epub 2017 Aug 14. Pathol Oncol Res. 2018. PMID: 28808873 Free article.
Hu-antigen R (HuR), a RNA-binding protein, is considered to play a crucial role in tumor development and progression by stabilizing or regulating a group of cellular mRNAs of cancer-related genes, such as cyclooxygenase-2 (COX-2). ...H
Hu-antigen R (HuR), a RNA-binding protein, is considered to play a crucial role in tumor development and progression by …
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