Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2004 1
2008 1
2012 1
2013 3
2014 2
2019 2
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

10 results
Results by year
Filters applied: . Clear all
Page 1
Differentiation and Proliferation of Intestinal Stem Cells and its Underlying Regulated Mechanisms during Weaning.
Chen X, Yang Z, Hu H, Duan W, Wang A, Dong Y, Gao W, Deng S, Cheng B, Li J, Sun N, Cheng Z, Guo W, Li Y, Gao Y. Chen X, et al. Curr Protein Pept Sci. 2019;20(7):690-695. doi: 10.2174/1389203720666190125101834. Curr Protein Pept Sci. 2019. PMID: 30678622 Review.
Secondly, the lack of EGF after weaning inhibits the expression of goblet cell maturation factors and makes it difficult for goblet cells and intestinal epithelial cells to mature. Finally, diet and endogenous synthesis lead to excessive polyamines in the intestine, which …
Secondly, the lack of EGF after weaning inhibits the expression of goblet cell maturation factors and makes it difficult for goblet c …
Human antigen R-mediated mRNA stabilization is required for ultraviolet B-induced autoinduction of amphiregulin in keratinocytes.
Nakayama H, Fukuda S, Matsushita N, Nishida-Fukuda H, Inoue H, Shirakata Y, Hashimoto K, Higashiyama S. Nakayama H, et al. J Biol Chem. 2013 Apr 12;288(15):10338-48. doi: 10.1074/jbc.M112.417527. Epub 2013 Feb 21. J Biol Chem. 2013. PMID: 23430747 Free PMC article.
The 3' UTR of AREG mRNA was responsible for binding to an mRNA-binding protein, human antigen R (HuR), and the interaction between AREG mRNA and HuR was enhanced by UVB. ...The HuR dependence of AREG mRNA and protein expression was also c …
The 3' UTR of AREG mRNA was responsible for binding to an mRNA-binding protein, human antigen R (HuR), and the i …
Glycyrrhetinic Acid Maintains Intestinal Homeostasis via HuR.
Chen G, Bei B, Feng Y, Li X, Jiang Z, Si JY, Qing DG, Zhang J, Li N. Chen G, et al. Front Pharmacol. 2019 May 16;10:535. doi: 10.3389/fphar.2019.00535. eCollection 2019. Front Pharmacol. 2019. PMID: 31156441 Free PMC article.
GA failed to promote proliferation and to suppress apoptosis after silencing HuR by siRNA in IEC-6 cells. Furthermore, with the model of small intestinal organoids developed from intestinal crypt stem cells, we found that GA could increase HuR and its downstream ki6 …
GA failed to promote proliferation and to suppress apoptosis after silencing HuR by siRNA in IEC-6 cells. Furthermore, with the model …
Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1alpha and EGF mRNA.
Sheflin LG, Zou AP, Spaulding SW. Sheflin LG, et al. Biochem Biophys Res Commun. 2004 Sep 17;322(2):644-51. doi: 10.1016/j.bbrc.2004.07.173. Biochem Biophys Res Commun. 2004. PMID: 15325278
Androgens regulate the level and subcellular shuttling of HuR, a major ARE-binding protein that stabilizes many ARE-mRNAs. Pull down of biotinylated 3'UTRs of HIF-1alpha or EGF enriches HuR on blots from Jurkat cell lysates 5-fold, and enriches the amount of …
Androgens regulate the level and subcellular shuttling of HuR, a major ARE-binding protein that stabilizes many ARE-mRNAs. Pull down …
Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells.
Hostetter C, Licata LA, Witkiewicz A, Costantino CL, Yeo CJ, Brody JR, Keen JC. Hostetter C, et al. Cancer Biol Ther. 2008 Sep;7(9):1496-506. doi: 10.4161/cbt.7.9.6490. Epub 2008 Sep 23. Cancer Biol Ther. 2008. PMID: 18769129
While much is known about overexpression of key growth promoting receptors including EGF, erbB2/Her2 and IGF receptors and subsequent activation of MAPK signaling associated with resistance, the underlying mechanism in the development of resistance still remains unknown. . …
While much is known about overexpression of key growth promoting receptors including EGF, erbB2/Her2 and IGF receptors and subsequent …
Interleukin-1/toll-like receptor-induced nuclear factor kappa B signaling participates in intima hyperplasia after carotid artery balloon injury in goto-kakizaki rats: a potential target therapy pathway.
Zhang X, Wang Y, Hu W, Li D, Zhou Z, Pan D, Wu W, Xu T. Zhang X, et al. PLoS One. 2014 Aug 1;9(8):e103794. doi: 10.1371/journal.pone.0103794. eCollection 2014. PLoS One. 2014. PMID: 25083789 Free PMC article.
Interleukin-1/Toll-like receptor (IL-1/TLR) signaling is involved in innate and adaptive immune responses, but whether and how the IL-1/TLR-induced nuclear factor kappa B (NFκB) pathway plays key roles in intimal formation is unclear. ...TLR4, IL-1 receptor associated kina …
Interleukin-1/Toll-like receptor (IL-1/TLR) signaling is involved in innate and adaptive immune responses, but whether and how the IL …
The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.
Giles KM, Daly JM, Beveridge DJ, Thomson AM, Voon DC, Furneaux HM, Jazayeri JA, Leedman PJ. Giles KM, et al. J Biol Chem. 2003 Jan 31;278(5):2937-46. doi: 10.1074/jbc.M208439200. Epub 2002 Nov 12. J Biol Chem. 2003. PMID: 12431987 Free article.
We found in human MDA-468 breast cancer cells that EGF up-regulates p21(WAF1) mRNA and protein, through a combination of increased mRNA stability and transcription. ...Over- and underexpression of HuR in MDA-468 cells did not affect EGF-induced p21(WAF …
We found in human MDA-468 breast cancer cells that EGF up-regulates p21(WAF1) mRNA and protein, through a combination of incre …
Beta-catenin/HuR post-transcriptional machinery governs cancer stem cell features in response to hypoxia.
D'Uva G, Bertoni S, Lauriola M, De Carolis S, Pacilli A, D'Anello L, Santini D, Taffurelli M, Ceccarelli C, Yarden Y, Montanaro L, Bonafé M, Storci G. D'Uva G, et al. PLoS One. 2013 Nov 15;8(11):e80742. doi: 10.1371/journal.pone.0080742. eCollection 2013. PLoS One. 2013. PMID: 24260469 Free PMC article.
In response to hypoxia, beta-catenin moves from the plasma membrane to the cytoplasm where it binds and stabilizes SNAI2 and CA9 mRNAs, in cooperation with the mRNA stabilizing protein HuR. ...In such cells, we unravel the generalized involvement of the beta-catenin-driven …
In response to hypoxia, beta-catenin moves from the plasma membrane to the cytoplasm where it binds and stabilizes SNAI2 and CA9 mRNAs, in c …
AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.
Merlen G, Gentric G, Celton-Morizur S, Foretz M, Guidotti JE, Fauveau V, Leclerc J, Viollet B, Desdouets C. Merlen G, et al. J Hepatol. 2014 Jan;60(1):152-9. doi: 10.1016/j.jhep.2013.08.025. Epub 2013 Sep 6. J Hepatol. 2014. PMID: 24012615
Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability.
Zhang J, Ouyang W, Li J, Zhang D, Yu Y, Wang Y, Li X, Huang C. Zhang J, et al. Toxicol Appl Pharmacol. 2012 Sep 1;263(2):218-24. doi: 10.1016/j.taap.2012.06.012. Epub 2012 Jun 28. Toxicol Appl Pharmacol. 2012. PMID: 22749963 Free PMC article.
Here, we have demonstrated that SAHA inhibited EGF-induced Cl41 cell transformation via the decrease of cyclin D1 mRNA stability and induction of G0/G1 growth arrest. ...Consistent with downregulation of cyclin D1 mRNA stability, SAHA treatment also attenuated HuR e …
Here, we have demonstrated that SAHA inhibited EGF-induced Cl41 cell transformation via the decrease of cyclin D1 mRNA stability and …
Feedback