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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 1
2004 1
2005 4
2006 2
2007 2
2008 9
2009 8
2010 10
2011 4
2012 5
2013 11
2014 9
2015 7
2016 7
2017 9
2018 6
2019 8
2020 8
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101 results
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ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2.
Zhu H, Gan X, Jiang X, Diao S, Wu H, Hu J. Zhu H, et al. J Exp Clin Cancer Res. 2019 Apr 15;38(1):163. doi: 10.1186/s13046-019-1159-2. J Exp Clin Cancer Res. 2019. PMID: 30987661 Free PMC article.
BACKGROUND: ALKBH5 regulated the malignant behavior of breast cancer and glioblastoma. However, the expression and function of ALKBH5 in epithelial ovarian cancer have not yet been determined. ...Mechanical study revealed that ALKBH5 physically interacted wit …
BACKGROUND: ALKBH5 regulated the malignant behavior of breast cancer and glioblastoma. However, the expression and function of …
A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability.
Jadaliha M, Gholamalamdari O, Tang W, Zhang Y, Petracovici A, Hao Q, Tariq A, Kim TG, Holton SE, Singh DK, Li XL, Freier SM, Ambs S, Bhargava R, Lal A, Prasanth SG, Ma J, Prasanth KV. Jadaliha M, et al. PLoS Genet. 2018 Nov 29;14(11):e1007802. doi: 10.1371/journal.pgen.1007802. eCollection 2018 Nov. PLoS Genet. 2018. PMID: 30496290 Free PMC article.
Aberrant expression of a significant number of lncRNAs is observed in various diseases, including cancer. To gain insights into the role of lncRNAs in breast cancer progression, we performed genome-wide transcriptome analyses in an isogenic, triple negative …
Aberrant expression of a significant number of lncRNAs is observed in various diseases, including cancer. To gain insights into the r …
CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.
Sadej R, Lu X, Turczyk L, Novitskaya V, Lopez-Clavijo AF, Kordek R, Potemski P, Wakelam MJO, Romanska-Knight H, Berditchevski F. Sadej R, et al. J Cell Sci. 2018 Oct 29;131(21):jcs220640. doi: 10.1242/jcs.220640. J Cell Sci. 2018. PMID: 30257985 Free article.
Depletion of CD151 in breast cancer cells resulted in an increased level of FGFR2. Accordingly, an inverse correlation between CD151 and FGFR2 was observed in breast cancer tissues. CD151-dependent regulation of the FGFR2 expression relies on post-tran …
Depletion of CD151 in breast cancer cells resulted in an increased level of FGFR2. Accordingly, an inverse correlation between …
The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial-Mesenchymal Transition in Breast Cancer.
Latorre E, Carelli S, Raimondi I, D'Agostino V, Castiglioni I, Zucal C, Moro G, Luciani A, Ghilardi G, Monti E, Inga A, Di Giulio AM, Gorio A, Provenzani A. Latorre E, et al. Cancer Res. 2016 May 1;76(9):2626-36. doi: 10.1158/0008-5472.CAN-15-2018. Epub 2016 Apr 20. Cancer Res. 2016. PMID: 27197265 Free article.
In this study, we show that a ribonucleoprotein complex including the long noncoding RNA MALAT1 and the RNA-binding protein HuR (ELAVL1) binds the CD133 promoter region to regulate its expression. In luminal nonmetastatic MCF-7 breast cancer cells, …
In this study, we show that a ribonucleoprotein complex including the long noncoding RNA MALAT1 and the RNA-binding protein HuR (E
HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A.
Andrade D, Mehta M, Griffith J, Oh S, Corbin J, Babu A, De S, Chen A, Zhao YD, Husain S, Roy S, Xu L, Aube J, Janknecht R, Gorospe M, Herman T, Ramesh R, Munshi A. Andrade D, et al. Cancers (Basel). 2019 Dec 13;11(12):2014. doi: 10.3390/cancers11122014. Cancers (Basel). 2019. PMID: 31847141 Free PMC article.
Here, we report that ARID1A is regulated by human antigen R (HuR), an RNA-binding protein that is highly expressed in a wide range of cancers and enables resistance to chemotherapy and radiation. ...Taken together, our work shows that HuR and AR …
Here, we report that ARID1A is regulated by human antigen R (HuR), an RNA-binding protein that is highly express …
Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.
Bowler E, Porazinski S, Uzor S, Thibault P, Durand M, Lapointe E, Rouschop KMA, Hancock J, Wilson I, Ladomery M. Bowler E, et al. BMC Cancer. 2018 Apr 2;18(1):355. doi: 10.1186/s12885-018-4227-7. BMC Cancer. 2018. PMID: 29606096 Free PMC article.
We also observed that the splice factor kinase CLK3, but not CLK2 and CLK4, was also induced in hypoxic DU145 prostate, HT29 colon and MCF7 breast cancer cell lines. ...The expression of several splice factors and splice factor kinases increases during hypoxia, in p …
We also observed that the splice factor kinase CLK3, but not CLK2 and CLK4, was also induced in hypoxic DU145 prostate, HT29 colon and MCF7 …
Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.
Liu Y, Li J, Ma Z, Zhang J, Wang Y, Yu Z, Lin X, Xu Z, Su Q, An L, Zhou Y, Ma X, Yang Y, Wang F, Chen Q, Zhang Y, Wang J, Zheng H, Shi A, Yu S, Zhang J, Zhao W, Chen L. Liu Y, et al. Cancer Med. 2019 Feb;8(2):729-741. doi: 10.1002/cam4.1938. Epub 2019 Jan 16. Cancer Med. 2019. PMID: 30652415 Free PMC article.
Protein Kinase D (PKD) family contains PKD1, PKD2, and PKD3 in human. Compared to consistent tumor-suppressive functions of PKD1 in breast cancer, how PKD2/3 functions in breast cancer are not fully understood. ...ELAVL1 was identified as …
Protein Kinase D (PKD) family contains PKD1, PKD2, and PKD3 in human. Compared to consistent tumor-suppressive functions of PKD1 in …
Unearthing Regulatory Axes of Breast Cancer circRNAs Networks to Find Novel Targets and Fathom Pivotal Mechanisms.
Afzali F, Salimi M. Afzali F, et al. Interdiscip Sci. 2019 Dec;11(4):711-722. doi: 10.1007/s12539-019-00339-6. Epub 2019 Jun 11. Interdiscip Sci. 2019. PMID: 31187432
Circular RNAs (circRNAs) possess valuable characteristics for both diagnosis and treatment of several human cancers including breast cancer (BC). ...Rooting from the identified total of 25 co-differentially expressed circRNAs (DECs) between triple negative (T …
Circular RNAs (circRNAs) possess valuable characteristics for both diagnosis and treatment of several human cancers including brea
Integrated Regulation of HuR by Translation Repression and Protein Degradation Determines Pulsatile Expression of p53 Under DNA Damage.
Guha A, Ahuja D, Das Mandal S, Parasar B, Deyasi K, Roy D, Sharma V, Willard B, Ghosh A, Ray PS. Guha A, et al. iScience. 2019 May 31;15:342-359. doi: 10.1016/j.isci.2019.05.002. Epub 2019 May 4. iScience. 2019. PMID: 31103853 Free PMC article.
Expression of tumor suppressor p53 is regulated at multiple levels, disruption of which often leads to cancer. We have adopted an approach combining computational systems modeling with experimental validation to elucidate the translation regulatory network that controls p5 …
Expression of tumor suppressor p53 is regulated at multiple levels, disruption of which often leads to cancer. We have adopted an app …
MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer.
Thorne JL, Battaglia S, Baxter DE, Hayes JL, Hutchinson SA, Jana S, Millican-Slater RA, Smith L, Teske MC, Wastall LM, Hughes TA. Thorne JL, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):996-1006. doi: 10.1016/j.bbagrm.2018.08.005. Epub 2018 Aug 31. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 30343695
We characterised the ABCB1 UTRs in primary breast cancer cells and identified UTR sequences that responded to miR-19b despite lacking a canonical binding site. Sequences did, however, contain consensus sites for the RNA-binding protein HuR. We demonstrated th …
We characterised the ABCB1 UTRs in primary breast cancer cells and identified UTR sequences that responded to miR-19b despite …
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