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Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer.
Woo HH, Zhou Y, Yi X, David CL, Zheng W, Gilmore-Hebert M, Kluger HM, Ulukus EC, Baker T, Stoffer JB, Chambers SK. Woo HH, et al. Oncogene. 2009 Mar 5;28(9):1176-86. doi: 10.1038/onc.2008.469. Epub 2009 Jan 19. Oncogene. 2009. PMID: 19151756
We described c-fms mRNA as a direct target of HuR in vivo, and that HuR bound specifically to a 69-nt region containing 'CUU' motifs in 3'UTR c-fms RNA. Overexpressing or silencing HuR significantly up- or down-regulated c-fms RNA expression, respectively. We …
We described c-fms mRNA as a direct target of HuR in vivo, and that HuR bound specifically to a 69-nt region containing 'CUU' …
Posttranscriptional suppression of proto-oncogene c-fms expression by vigilin in breast cancer.
Woo HH, Yi X, Lamb T, Menzl I, Baker T, Shapiro DJ, Chambers SK. Woo HH, et al. Mol Cell Biol. 2011 Jan;31(1):215-25. doi: 10.1128/MCB.01031-10. Epub 2010 Oct 25. Mol Cell Biol. 2011. PMID: 20974809 Free PMC article.
By binding a novel non-AU-rich 69-nucleotide (nt) c-fms 3' UTR sequence, we previously identified HuR as a promoter of c-fms proto-oncogene mRNA. ...Altering association of either vigilin or HuR with c-fms mRNA in vivo reciprocally affected mRNA association with the …
By binding a novel non-AU-rich 69-nucleotide (nt) c-fms 3' UTR sequence, we previously identified HuR as a promoter of c-fms proto-on …
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