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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2007 2
2008 2
2009 2
2010 2
2011 6
2012 3
2013 8
2014 6
2015 8
2016 8
2017 10
2018 14
2019 20
2020 11
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87 results
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Page 1
Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression.
Panneerdoss S, Eedunuri VK, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, Abdelfattah N, Onyeagucha BC, Cui X, Lai Z, Mohammad TA, Gupta YK, Huang TH, Huang Y, Chen Y, Rao MK. Panneerdoss S, et al. Sci Adv. 2018 Oct 3;4(10):eaar8263. doi: 10.1126/sciadv.aar8263. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30306128 Free PMC article.
We report that altering m(6)A levels by silencing either N (6)-adenosine methyltransferase METTL14 (methyltransferase-like 14) or demethylase ALKBH5 (ALKB homolog 5) inhibits cancer growth and invasion. ...Furthermore, we show that ALKBH5/METTL14 constitute a positi …
We report that altering m(6)A levels by silencing either N (6)-adenosine methyltransferase METTL14 (methyltransferase-like 14) or dem …
Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes.
Chen Y, Yang F, Fang E, Xiao W, Mei H, Li H, Li D, Song H, Wang J, Hong M, Wang X, Huang K, Zheng L, Tong Q. Chen Y, et al. Cell Death Differ. 2019 Jul;26(7):1346-1364. doi: 10.1038/s41418-018-0220-6. Epub 2018 Oct 19. Cell Death Differ. 2019. PMID: 30341421 Free PMC article.
CircAGO2 promotes the growth, invasion, and metastasis of cancer cells in vitro and in vivo. Mechanistic studies reveal that circAGO2 physically interacts with human antigen R (HuR) protein to facilitate its activation and enrichment on the 3'-u …
CircAGO2 promotes the growth, invasion, and metastasis of cancer cells in vitro and in vivo. Mechanistic studies reveal that circAGO2 …
Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma.
Zhang DY, Zou XJ, Cao CH, Zhang T, Lei L, Qi XL, Liu L, Wu DH. Zhang DY, et al. Theranostics. 2018 Jun 13;8(14):3751-3765. doi: 10.7150/thno.22493. eCollection 2018. Theranostics. 2018. PMID: 30083257 Free PMC article.
Forced expression of MIR22HG in HCC cells significantly suppressed proliferation, invasion, and metastasis in vitro and in vivo. ...Additionally, MIR22HG directly interacted with HuR and regulated its subcellular localization. MIR22HG competitively bound to human
Forced expression of MIR22HG in HCC cells significantly suppressed proliferation, invasion, and metastasis in vitro and in vivo. ...A …
RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.
Zarei M, Lal S, Vaziri-Gohar A, O'Hayer K, Gunda V, Singh PK, Brody JR, Winter JM. Zarei M, et al. Mol Cancer Res. 2019 Feb;17(2):508-520. doi: 10.1158/1541-7786.MCR-18-0557. Epub 2018 Sep 28. Mol Cancer Res. 2019. PMID: 30266754 Free PMC article.
Recently, it was observed that the regulatory RNA-binding protein, HuR (ELAVL1), protects nutrient-deprived cancer cells without IDH1 mutations, by stabilizing WT.IDH1 transcripts. ...Proliferation and invasion were adversely affected after HuR suppres …
Recently, it was observed that the regulatory RNA-binding protein, HuR (ELAVL1), protects nutrient-deprived cancer cells witho …
Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation.
Yang F, Hu A, Li D, Wang J, Guo Y, Liu Y, Li H, Chen Y, Wang X, Huang K, Zheng L, Tong Q. Yang F, et al. Mol Cancer. 2019 Nov 13;18(1):158. doi: 10.1186/s12943-019-1094-z. Mol Cancer. 2019. PMID: 31718709 Free PMC article.
Our previous study has identified that circAGO2 drives gastric cancer progression through activating human antigen R (HuR), a protein stabilizing AU-rich element-containing mRNAs. ...Ectopic expression of circ-HuR suppressed the growth, invas
Our previous study has identified that circAGO2 drives gastric cancer progression through activating human antigen R ( …
ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2.
Zhu H, Gan X, Jiang X, Diao S, Wu H, Hu J. Zhu H, et al. J Exp Clin Cancer Res. 2019 Apr 15;38(1):163. doi: 10.1186/s13046-019-1159-2. J Exp Clin Cancer Res. 2019. PMID: 30987661 Free PMC article.
Cell proliferation assay and Matrigel invasion assays were used to detect cell proliferation and invasion, respectively. The nude mouse tumor formation experiment was used to evaluate the growth of cells in vivo. ...Mechanical study revealed that ALKBH5 physically i …
Cell proliferation assay and Matrigel invasion assays were used to detect cell proliferation and invasion, respectively. The n …
MicroRNA-139-3p Inhibits The Growth And Metastasis Of Ovarian Cancer By Inhibiting ELAVL1.
Xue F, Li QR, Xu YH, Zhou HB. Xue F, et al. Onco Targets Ther. 2019 Nov 5;12:8935-8945. doi: 10.2147/OTT.S210739. eCollection 2019. Onco Targets Ther. 2019. PMID: 31806990 Free PMC article.
The proliferation, colony formation, migration and invasion of ovarian cancer cell were determined, respectively. A luciferase reporter assay was used to confirm ELAV Like RNA Binding Protein 1 (ELAVL1) was a target gene of miR-139-3p. ...Furthermore, the exp …
The proliferation, colony formation, migration and invasion of ovarian cancer cell were determined, respectively. A luciferase report …
LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis.
Hu YP, Jin YP, Wu XS, Yang Y, Li YS, Li HF, Xiang SS, Song XL, Jiang L, Zhang YJ, Huang W, Chen SL, Liu FT, Chen C, Zhu Q, Chen HZ, Shao R, Liu YB. Hu YP, et al. Mol Cancer. 2019 Nov 21;18(1):167. doi: 10.1186/s12943-019-1097-9. Mol Cancer. 2019. PMID: 31752906 Free PMC article.
Overexpression or knockdown of lncRNA-HGBC in GBC cell lines resulted in increased or decreased, respectively, cell proliferation and invasion in vitro and in xenografted tumors. LncRNA-HGBC specifically bound to RNA binding protein Hu Antigen R (HuR) …
Overexpression or knockdown of lncRNA-HGBC in GBC cell lines resulted in increased or decreased, respectively, cell proliferation and inv
Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling.
Wu JI, Lin YP, Tseng CW, Chen HJ, Wang LH. Wu JI, et al. Sci Rep. 2019 Jan 29;9(1):845. doi: 10.1038/s41598-018-37443-4. Sci Rep. 2019. PMID: 30696915 Free PMC article.
Knockdown of Crabp2 decreased migration, invasion, anoikis resistance, and in vivo metastasis. Crabp2 was co-immunoprecipitated with HuR, and overexpression of Crabp2 increased HuR levels, which promoted integrin β1/FAK/ERK signaling. Inhibition of HuR
Knockdown of Crabp2 decreased migration, invasion, anoikis resistance, and in vivo metastasis. Crabp2 was co-immunoprecipitated with …
Functional Role of a Novel Long Noncoding RNA TTN-AS1 in Esophageal Squamous Cell Carcinoma Progression and Metastasis.
Lin C, Zhang S, Wang Y, Wang Y, Nice E, Guo C, Zhang E, Yu L, Li M, Liu C, Hu L, Hao J, Qi W, Xu H. Lin C, et al. Clin Cancer Res. 2018 Jan 15;24(2):486-498. doi: 10.1158/1078-0432.CCR-17-1851. Epub 2017 Nov 3. Clin Cancer Res. 2018. PMID: 29101304 Free article.
Moreover, lncRNA-TTN-AS1 also induces FSCN1 expression by sponging miR-133b and upregulation of mRNA-stabilizing protein HuR, which further promotes ESCC invasion cascades. ...
Moreover, lncRNA-TTN-AS1 also induces FSCN1 expression by sponging miR-133b and upregulation of mRNA-stabilizing protein HuR, which f …
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