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ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2.
Zhu H, Gan X, Jiang X, Diao S, Wu H, Hu J. Zhu H, et al. J Exp Clin Cancer Res. 2019 Apr 15;38(1):163. doi: 10.1186/s13046-019-1159-2. J Exp Clin Cancer Res. 2019. PMID: 30987661 Free PMC article.
RESULTS: The expression of ALKBH5 was found to be increased in epithelial ovarian cancer tissue as compared to the normal ovarian tissues. ...CONCLUSION: Overall, the present study identified ALKBH5 as a candidate oncogene in epithelial ovarian canc
RESULTS: The expression of ALKBH5 was found to be increased in epithelial ovarian cancer tissue as compared to the normal o
LncRNA FAM83H-AS1 contributes to the radioresistance, proliferation, and metastasis in ovarian cancer through stabilizing HuR protein.
Dou Q, Xu Y, Zhu Y, Hu Y, Yan Y, Yan H. Dou Q, et al. Eur J Pharmacol. 2019 Jun 5;852:134-141. doi: 10.1016/j.ejphar.2019.03.002. Epub 2019 Mar 2. Eur J Pharmacol. 2019. PMID: 30831080
Ovarian cancer (OC) is a major cause of cancer-related deaths in women all over the world. The easy metastasis of OC and the problem of radioresistance are serious issues remaining to be overcome. ...In conclusion, present study proved that FAM83H-AS1 contrib
Ovarian cancer (OC) is a major cause of cancer-related deaths in women all over the world. The easy metastasis of OC an
MicroRNA-139-3p Inhibits The Growth And Metastasis Of Ovarian Cancer By Inhibiting ELAVL1.
Xue F, Li QR, Xu YH, Zhou HB. Xue F, et al. Onco Targets Ther. 2019 Nov 5;12:8935-8945. doi: 10.2147/OTT.S210739. eCollection 2019. Onco Targets Ther. 2019. PMID: 31806990 Free PMC article.
The proliferation, colony formation, migration and invasion of ovarian cancer cell were determined, respectively. A luciferase reporter assay was used to confirm ELAV Like RNA Binding Protein 1 (ELAVL1) was a target gene of miR-139-3p. ...Furthermore, …
The proliferation, colony formation, migration and invasion of ovarian cancer cell were determined, respectively. A luciferase …
Long noncoding RNA lncARSR promotes epithelial ovarian cancer cell proliferation and invasion by association with HuR and miR-200 family.
Shu C, Yan D, Mo Y, Gu J, Shah N, He J. Shu C, et al. Am J Cancer Res. 2018 Jun 1;8(6):981-992. eCollection 2018. Am J Cancer Res. 2018. PMID: 30034936 Free PMC article.
Epithelial ovarian cancer (EOC) is the fifth leading cause of female cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) are emerging as crucial regulators in various biological processes through diverse mechanisms. ...Further investigations showe …
Epithelial ovarian cancer (EOC) is the fifth leading cause of female cancer-related deaths worldwide. Long non-coding R …
HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer.
Chai Y, Liu J, Zhang Z, Liu L. Chai Y, et al. Cancer Med. 2016 Jul;5(7):1588-98. doi: 10.1002/cam4.710. Epub 2016 Apr 14. Cancer Med. 2016. PMID: 27075229 Free PMC article.
The nuclear paraspeckle assembly transcript 1 (NEAT1) is one of the most highly regulated lncRNAs in recent genomic datasets, however, its biological role and regulatory mechanism in ovarian cancer (OC) development and progression are poorly defined. ...These result …
The nuclear paraspeckle assembly transcript 1 (NEAT1) is one of the most highly regulated lncRNAs in recent genomic datasets, however, its b …
Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy.
Huang YH, Peng W, Furuuchi N, DuHadaway JB, Jimbo M, Pirritano A, Dunton CJ, Daum GS, Leiby BE, Brody JR, Sawicki JA. Huang YH, et al. Oncotarget. 2016 Apr 19;7(16):21812-24. doi: 10.18632/oncotarget.7840. Oncotarget. 2016. PMID: 26943573 Free PMC article.
Ribonucleoprotein immunoprecipitation (RNP-IP) analysis of ovarian cancer cells in culture showed that cytoplasmic HuR increases deoxycytidine kinase (dCK), a metabolic enzyme that activates gemcitabine. ...Treatment of ovarian cancer cells with …
Ribonucleoprotein immunoprecipitation (RNP-IP) analysis of ovarian cancer cells in culture showed that cytoplasmic HuR
MiR-200c and HuR in ovarian cancer.
Prislei S, Martinelli E, Mariani M, Raspaglio G, Sieber S, Ferrandina G, Shahabi S, Scambia G, Ferlini C. Prislei S, et al. BMC Cancer. 2013 Feb 8;13:72. doi: 10.1186/1471-2407-13-72. BMC Cancer. 2013. PMID: 23394580 Free PMC article.
Nanofluidic technology and immunohistochemistry were used to analyze the expression of HuR, TUBB3 and miR-200c in 220 ovarian cancer patients. ...CONCLUSION: This study suggests a model for the combined regulatory activity of miR-200c and HuR on TUBB3 …
Nanofluidic technology and immunohistochemistry were used to analyze the expression of HuR, TUBB3 and miR-200c in 220 ovarian
Selecting key genes associated with ovarian cancer based on differential expression network.
Lu X, Wang J, Shan X, Li Y. Lu X, et al. J BUON. 2017 Jan-Feb;22(1):48-57. J BUON. 2017. PMID: 28365935 Free article.
PURPOSE: The purpose in this study was to select key genes related to ovarian cancer. METHODS: The gene expression profiles of E-GEOD-6008, E-GEOD-26712, E-GEOD-27651, E-GEOD-14001 were obtained from ArrayExpress database (http://www.ebi.ac.uk/arrayexpress/). ...CON …
PURPOSE: The purpose in this study was to select key genes related to ovarian cancer. METHODS: The gene expression profiles of …
E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C.
Sang XB, Zong ZH, Wang LL, Wu DD, Chen S, Liu BL, Zhao Y. Sang XB, et al. Oncotarget. 2017 Feb 28;8(9):14777-14793. doi: 10.18632/oncotarget.14833. Oncotarget. 2017. PMID: 28146423 Free PMC article.
After E2F1 plasmid transfection and E2F1-microRNA-519d (miR-519d)/si-RhoC (Ras homolog gene family member C) co-transfection, ovarian cancer cell phenotypes and the related molecules were examined in vitro and in vivo. ...E2F1 overexpression increased RhoC, Bcl-2, c …
After E2F1 plasmid transfection and E2F1-microRNA-519d (miR-519d)/si-RhoC (Ras homolog gene family member C) co-transfection, ovarian
Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer.
Prislei S, Martinelli E, Zannoni GF, Petrillo M, Filippetti F, Mariani M, Mozzetti S, Raspaglio G, Scambia G, Ferlini C. Prislei S, et al. Oncotarget. 2015 Aug 7;6(22):18966-79. doi: 10.18632/oncotarget.3943. Oncotarget. 2015. PMID: 26136338 Free PMC article.
We demonstrated a role of ZEB2 in migration and anchorage-independent cell growth in ovarian cancer, as shown by ZEB2 silencing. ...Analysis of ZEB2 and HuR expression in ovarian cancers revealed that nuclear ZEB2 is localized in tumor leading edge and …
We demonstrated a role of ZEB2 in migration and anchorage-independent cell growth in ovarian cancer, as shown by ZEB2 silencin …
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