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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 2
2006 3
2007 1
2008 2
2009 8
2010 7
2011 5
2012 4
2013 10
2014 5
2015 8
2016 4
2017 4
2018 9
2019 6
2020 1
2021 6
2022 11
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83 results
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LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis.
Hu YP, Jin YP, Wu XS, Yang Y, Li YS, Li HF, Xiang SS, Song XL, Jiang L, Zhang YJ, Huang W, Chen SL, Liu FT, Chen C, Zhu Q, Chen HZ, Shao R, Liu YB. Hu YP, et al. Mol Cancer. 2019 Nov 21;18(1):167. doi: 10.1186/s12943-019-1097-9. Mol Cancer. 2019. PMID: 31752906 Free PMC article.
Overexpression or knockdown of lncRNA-HGBC in GBC cell lines resulted in increased or decreased, respectively, cell proliferation and invasion in vitro and in xenografted tumors. LncRNA-HGBC specifically bound to RNA binding protein Hu Antigen R (HuR) that in …
Overexpression or knockdown of lncRNA-HGBC in GBC cell lines resulted in increased or decreased, respectively, cell proliferation and invasi …
Circular RNA circDLC1 inhibits MMP1-mediated liver cancer progression via interaction with HuR.
Liu H, Lan T, Li H, Xu L, Chen X, Liao H, Chen X, Du J, Cai Y, Wang J, Li X, Huang J, Yuan K, Zeng Y. Liu H, et al. Theranostics. 2021 Jan 1;11(3):1396-1411. doi: 10.7150/thno.53227. eCollection 2021. Theranostics. 2021. PMID: 33391541 Free PMC article.
Mechanistic investigations revealed that circDLC1 could bind to RNA-binding protein HuR, which subsequently reduced the interaction between HuR and MMP1 mRNAs, and thus inhibited the expression of MMP1, ultimately contributing to inhibition of HCC progression. Concl …
Mechanistic investigations revealed that circDLC1 could bind to RNA-binding protein HuR, which subsequently reduced the interaction b …
Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
Frau M, Feo F, Pascale RM. Frau M, et al. J Hepatol. 2013 Oct;59(4):830-41. doi: 10.1016/j.jhep.2013.04.031. Epub 2013 May 7. J Hepatol. 2013. PMID: 23665184 Free article. Review.
All of these changes are reversed by SAM treatment in vivo or forced MAT1A overexpression or MAT2A inhibition in cultured HCC cells. In human HCC, MAT1A:MAT2A and MATI/III:MATII ratios correlate negatively with cell proliferation and genomic instability, and positively wit …
All of these changes are reversed by SAM treatment in vivo or forced MAT1A overexpression or MAT2A inhibition in cultured HCC cells. In h
The RNA-binding protein HuR in human cancer: A friend or foe?
Wu X, Xu L. Wu X, et al. Adv Drug Deliv Rev. 2022 May;184:114179. doi: 10.1016/j.addr.2022.114179. Epub 2022 Mar 3. Adv Drug Deliv Rev. 2022. PMID: 35248670 Review.
The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis elements present in mRNAs whose stability and translation are subject to regulation. The RBP Hu antigen R (HuR) is overexpressed in a wide variety of human canc …
The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis elements present in mRNAs whose stability and tr …
FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway.
Li Y, Xiong Y, Wang Z, Han J, Shi S, He J, Shen N, Wu W, Wang R, Lv W, Deng Y, Liu W. Li Y, et al. Cancer Cell Int. 2021 Oct 13;21(1):534. doi: 10.1186/s12935-021-02244-9. Cancer Cell Int. 2021. PMID: 34645466 Free PMC article.
Knockdown of FAM49B inhibited the proliferation and migration of BC cells in vitro and in vivo. Microarray analysis revealed that the Toll-like receptor signaling pathway was inhibited upon FAM49B knockdown. In addition, the gene interaction network and downstream protein …
Knockdown of FAM49B inhibited the proliferation and migration of BC cells in vitro and in vivo. Microarray analysis revealed that the Toll- …
Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors.
Lachiondo-Ortega S, Delgado TC, Baños-Jaime B, Velázquez-Cruz A, Díaz-Moreno I, Martínez-Chantar ML. Lachiondo-Ortega S, et al. Cancers (Basel). 2022 May 27;14(11):2666. doi: 10.3390/cancers14112666. Cancers (Basel). 2022. PMID: 35681645 Free PMC article. Review.
Hu antigen R (HuR) is a 36-kDa ubiquitous member of the ELAV/Hu family of RNA-binding proteins (RBPs), which plays an important role as a post-transcriptional regulator of specific RNAs under physiological and pathological conditions, including cancer. ...In …
Hu antigen R (HuR) is a 36-kDa ubiquitous member of the ELAV/Hu family of RNA-binding proteins (RBPs), which plays an i …
The RNA-Binding Protein HuR in Digestive System Tumors.
Song X, Shi X, Li W, Zhang F, Cai Z. Song X, et al. Biomed Res Int. 2020 Jul 24;2020:9656051. doi: 10.1155/2020/9656051. eCollection 2020. Biomed Res Int. 2020. PMID: 32775456 Free PMC article. Review.
Human antigen R (HuR) is a member of the Hu family of RNA-binding proteins. ...Herein, we review the relationships between HuR and digestive system tumors, demonstrating the importance of HuR in digestive system tumor diagnosis....
Human antigen R (HuR) is a member of the Hu family of RNA-binding proteins. ...Herein, we review the relationshi
HuR, TTP, and miR-133b expression in NSCLC and their association with prognosis.
Qian L, Ji AH, Zhang WJ, Zhao N. Qian L, et al. Eur Rev Med Pharmacol Sci. 2018 Jan;22(2):430-442. doi: 10.26355/eurrev_201801_14192. Eur Rev Med Pharmacol Sci. 2018. PMID: 29424924 Free article. Retracted.
No significant difference in DFS nor OS was observed between 68 HuR-positive and 42 HuR-negative patients (DFS, Log Rank p = 0.712; OS, Log Rank p = 0.220). However, DFS and OS were significantly different between miR-133b high-expression and low-expression patients …
No significant difference in DFS nor OS was observed between 68 HuR-positive and 42 HuR-negative patients (DFS, Log Rank p = 0 …
Cytoplasmic accumulation of ELAVL1 is an independent predictor of biochemical recurrence associated with genomic instability in prostate cancer.
Melling N, Taskin B, Hube-Magg C, Kluth M, Minner S, Koop C, Grob T, Graefen M, Heinzer H, Tsourlakis MC, Izbicki J, Wittmer C, Huland H, Simon R, Wilczak W, Sauter G, Steurer S, Schlomm T, Krech T. Melling N, et al. Prostate. 2016 Feb 15;76(3):259-72. doi: 10.1002/pros.23120. Epub 2015 Nov 2. Prostate. 2016. PMID: 26764246

Strong cytoplasmic ELAVL1 staining was further linked to presence of PTEN, 5q21, 6q15, and 3p13 deletions (P < 0.0001 each), an observation consistent with cytoplasmic ELAVL1 accumulation in case of genomic instability. The prognostic role of ELAVL1

Strong cytoplasmic ELAVL1 staining was further linked to presence of PTEN, 5q21, 6q15, and 3p13 deletions (P < 0.0001 each), an ob

Hu antigen R (HuR) heterogeneous expression quantification as a prognostic marker of melanoma.
Liaudet N, Fernandez M, Fontao L, Kaya G, Merat R. Liaudet N, et al. J Cutan Pathol. 2018 May;45(5):333-336. doi: 10.1111/cup.13119. Epub 2018 Feb 23. J Cutan Pathol. 2018. PMID: 29393978
The mainly nuclear RNA-binding protein human antigen R (HuR) regulates the protein expression of thousands of mRNAs, its own heterogeneous expression could therefore reflect tumor heterogeneity and plasticity. ...CONCLUSION: Our data need confirmation …
The mainly nuclear RNA-binding protein human antigen R (HuR) regulates the protein expression of thousands of mR …
83 results