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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1785 2
1799 1
1803 2
1808 1
1812 1
1816 1
1819 1
1824 1
1825 2
1826 1
1829 1
1847 1
1848 1
1853 1
1854 1
1855 1
1856 4
1859 1
1867 1
1873 1
1876 1
1878 2
1879 2
1880 1
1889 1
1894 2
1896 3
1897 2
1898 1
1901 1
1902 1
1903 1
1905 1
1906 2
1909 4
1910 4
1911 2
1912 4
1913 1
1916 6
1917 2
1918 5
1920 3
1924 3
1925 2
1926 3
1927 1
1928 2
1930 3
1931 3
1933 3
1934 3
1935 5
1937 2
1940 1
1942 1
1943 1
1946 8
1947 10
1948 11
1949 3
1950 6
1951 9
1952 9
1953 11
1954 27
1955 21
1956 24
1957 16
1958 20
1959 14
1960 16
1961 11
1962 17
1963 15
1964 11
1965 18
1966 13
1967 15
1968 18
1969 14
1970 20
1971 21
1972 19
1973 27
1974 24
1975 76
1976 77
1977 69
1978 54
1979 68
1980 59
1981 71
1982 80
1983 81
1984 91
1985 90
1986 98
1987 104
1988 119
1989 148
1990 119
1991 137
1992 165
1993 155
1994 156
1995 154
1996 174
1997 175
1998 185
1999 176
2000 184
2001 220
2002 200
2003 252
2004 250
2005 282
2006 300
2007 342
2008 350
2009 386
2010 415
2011 423
2012 468
2013 495
2014 520
2015 497
2016 541
2017 543
2018 569
2019 583
2020 678
2021 823
2022 793
2023 364

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12,531 results

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Page 1
Using antipsychotics for behavioral problems in children.
Shafiq S, Pringsheim T. Shafiq S, et al. Expert Opin Pharmacother. 2018 Sep;19(13):1475-1488. doi: 10.1080/14656566.2018.1509069. Epub 2018 Aug 13. Expert Opin Pharmacother. 2018. PMID: 30102079 Review.
AREAS COVERED: The authors systematically analyze the results of randomized controlled trials of second and third generation antipsychotics for irritability in ASD and aggressive and disruptive behavior in DBD with or without low IQ and ADHD. ...EXPERT OPINION: There is ev …
AREAS COVERED: The authors systematically analyze the results of randomized controlled trials of second and third generation antipsychotics …
Irritability in Huntington's Disease.
Karagas NE, Rocha NP, Stimming EF. Karagas NE, et al. J Huntingtons Dis. 2020;9(2):107-113. doi: 10.3233/JHD-200397. J Huntingtons Dis. 2020. PMID: 32417789 Free PMC article. Review.
Huntington's disease (HD) is a heritable and fatal neurodegenerative disease characterized by a triad of motor, cognitive and neuropsychiatric symptoms. ...While these therapies offer relief to individuals suffering from irritability in HD, they are often not suffic …
Huntington's disease (HD) is a heritable and fatal neurodegenerative disease characterized by a triad of motor, cognitive and neurops …
Traits of empathy and anger: implications for psychopathy and other disorders associated with aggression.
Blair RJR. Blair RJR. Philos Trans R Soc Lond B Biol Sci. 2018 Apr 19;373(1744):20170155. doi: 10.1098/rstb.2017.0155. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29483341 Free PMC article. Review.
Empathy and anger are two social emotions that modulate an individual's risk for aggression. Empathy is an emotional reaction to another individual's emotional state. ...Reduced empathy, seen in psychopathy, increases the risk for goal-directed aggression. Atypicall …
Empathy and anger are two social emotions that modulate an individual's risk for aggression. Empathy is an emotional reaction to anot …
Pharmacologic Treatment of Severe Irritability and Problem Behaviors in Autism: A Systematic Review and Meta-analysis.
Fung LK, Mahajan R, Nozzolillo A, Bernal P, Krasner A, Jo B, Coury D, Whitaker A, Veenstra-Vanderweele J, Hardan AY. Fung LK, et al. Pediatrics. 2016 Feb;137 Suppl 2:S124-35. doi: 10.1542/peds.2015-2851K. Pediatrics. 2016. PMID: 26908468 Review.
BACKGROUND: Autism spectrum disorder (ASD) is increasingly recognized as a public health issue. Irritability and aggression (IA) often negatively affect the lives of people with ASD and their families. ...The primary study outcome measure was the effect size of reduction i …
BACKGROUND: Autism spectrum disorder (ASD) is increasingly recognized as a public health issue. Irritability and aggression (IA) ofte …
Treatment of Autism Spectrum Disorder in Children and Adolescents.
DeFilippis M, Wagner KD. DeFilippis M, et al. Psychopharmacol Bull. 2016 Aug 15;46(2):18-41. Psychopharmacol Bull. 2016. PMID: 27738378 Free PMC article.
Risperidone and aripiprazole are currently the only medications FDA approved for symptoms associated with autism spectrum disorders, targeting the irritability often seen with this diagnosis. Children and adolescents with autism spectrum disorder appear to be more suscepti …
Risperidone and aripiprazole are currently the only medications FDA approved for symptoms associated with autism spectrum disorders, targeti …
Advances in the Conceptualization, Assessment, and Treatment of Pediatric Irritability.
Roy AK, Comer JS. Roy AK, et al. Behav Ther. 2020 Mar;51(2):207-210. doi: 10.1016/j.beth.2019.10.010. Epub 2019 Nov 26. Behav Ther. 2020. PMID: 32138932
Pediatric irritability is a functionally impairing transdiagnostic symptom underlying a substantial proportion of child mental health referrals. ...At this critical stage in the study of pediatric irritability, this special series brings together the latest work fro …
Pediatric irritability is a functionally impairing transdiagnostic symptom underlying a substantial proportion of child mental health …
Mood dysregulation.
Mikita N, Stringaris A. Mikita N, et al. Eur Child Adolesc Psychiatry. 2013 Feb;22 Suppl 1(Suppl 1):S11-6. doi: 10.1007/s00787-012-0355-9. Eur Child Adolesc Psychiatry. 2013. PMID: 23229139 Free PMC article. Review.
This article focuses on two key components of this debate that are often treated under the collective term mood dysregulation: the first is chronic irritability (and the proposed DSM-5 category of disruptive mood dysregulation disorder) and the other concerns …
This article focuses on two key components of this debate that are often treated under the collective term mood dysregulation: the fi …
How and Why Are Irritability and Depression Linked?
Vidal-Ribas P, Stringaris A. Vidal-Ribas P, et al. Child Adolesc Psychiatr Clin N Am. 2021 Apr;30(2):401-414. doi: 10.1016/j.chc.2020.10.009. Child Adolesc Psychiatr Clin N Am. 2021. PMID: 33743947 Free PMC article. Review.
Based on its course over time, irritability is linked to depression cross-sectionally and longitudinally. Cross-sectionally, irritability takes an episodic form as a symptom in pediatric depression; yet, irritability in the absence of depressed mood or …
Based on its course over time, irritability is linked to depression cross-sectionally and longitudinally. Cross-sectionally, irrit …
Editorial: The Boundaries of Irritability and Implications for Measurement.
Mazefsky CA. Mazefsky CA. J Am Acad Child Adolesc Psychiatry. 2022 May;61(5):610-611. doi: 10.1016/j.jaac.2022.02.001. Epub 2022 Feb 10. J Am Acad Child Adolesc Psychiatry. 2022. PMID: 35151791 Free PMC article.
Irritability is a defining feature or symptom in at least 15 DSM-5 disorders,(1) and this does not even account for many more disorders that commonly co-occur with irritability. ...Unfortunately, there is a lack of consensus on the definition of irritability. …
Irritability is a defining feature or symptom in at least 15 DSM-5 disorders,(1) and this does not even account for many more disorde …
Prodrome in epilepsy.
Besag FMC, Vasey MJ. Besag FMC, et al. Epilepsy Behav. 2018 Jun;83:219-233. doi: 10.1016/j.yebeh.2018.03.019. Epub 2018 Apr 10. Epilepsy Behav. 2018. PMID: 29650466 Review.
The most frequent symptoms were "funny feeling" (10.4%), confusion (9.0%), anxiety (8.6%), and irritability (7.7%), but other features were also reported. The duration of prodrome was typically between 10min and 3days, with most prodromes lasting for between 30min and 24h. …
The most frequent symptoms were "funny feeling" (10.4%), confusion (9.0%), anxiety (8.6%), and irritability (7.7%), but other feature …
12,531 results
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