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Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
Goel A, Aggarwal BB. Goel A, et al. Nutr Cancer. 2010;62(7):919-30. doi: 10.1080/01635581.2010.509835. Nutr Cancer. 2010. PMID: 20924967 Review.
How curcumin acts as a chemosensitizer and radiosensitizer has also been studied extensively. For example, it downregulates various growth regulatory pathways and specific genetic targets including genes for NF-kappaB, STAT3, COX2, Akt, antiapoptotic proteins, growt …
How curcumin acts as a chemosensitizer and radiosensitizer has also been studied extensively. For example, it downregulates va …
Multitargeting by curcumin as revealed by molecular interaction studies.
Gupta SC, Prasad S, Kim JH, Patchva S, Webb LJ, Priyadarsini IK, Aggarwal BB. Gupta SC, et al. Nat Prod Rep. 2011 Nov;28(12):1937-55. doi: 10.1039/c1np00051a. Epub 2011 Oct 6. Nat Prod Rep. 2011. PMID: 21979811 Free PMC article. Review.
Curcumin (diferuloylmethane), the active ingredient in turmeric (Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant, chemopreventive, chemosensitization, and radiosensitization activities. The pleiotropic activities attributed to c …
Curcumin (diferuloylmethane), the active ingredient in turmeric (Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, an …
New mechanisms and therapeutic potential of curcumin for colorectal cancer.
Villegas I, Sánchez-Fidalgo S, Alarcón de la Lastra C. Villegas I, et al. Mol Nutr Food Res. 2008 Sep;52(9):1040-61. doi: 10.1002/mnfr.200700280. Mol Nutr Food Res. 2008. PMID: 18655004 Review.
Over the last few years, a number of studies have provided evidence of its main pharmacological properties including chemosensitizing, radiosensitizing, wound healing activities, antimicrobial, antiviral, antifungical, immunomodulatory, antioxidant and anti-inflamma …
Over the last few years, a number of studies have provided evidence of its main pharmacological properties including chemosensitizing
Combinations of the antioxidants sulforaphane or curcumin and the conventional antineoplastics cisplatin or doxorubicin as prospects for anticancer chemotherapy.
Negrette-Guzmán M. Negrette-Guzmán M. Eur J Pharmacol. 2019 Sep 15;859:172513. doi: 10.1016/j.ejphar.2019.172513. Epub 2019 Jun 29. Eur J Pharmacol. 2019. PMID: 31260654 Review.
Nuclear factor erythroid 2-related factor 2 (Nrf2) has been identified as a mediator of the cytoprotection but it is not regularly associated with tumor chemosensitization. However, some Nrf2 inducers could be exerting cytoprotective and chemosensitizing roles throu …
Nuclear factor erythroid 2-related factor 2 (Nrf2) has been identified as a mediator of the cytoprotection but it is not regularly associate …