The DnaA inhibitor SirA acts in the same pathway as Soj (ParA) to facilitate oriC segregation during Bacillus subtilis sporulation.
Mol Microbiol. 2016 Nov;102(3):530-544. doi: 10.1111/mmi.13477. Epub 2016 Aug 25.
Mol Microbiol. 2016.
PMID: 27489185
Free article.
By analyzing loss-of-function variants of both SirA and DnaA, we observe that SirA's ability to inhibit DNA replication can be genetically separated from its role in oriC capture. ...One such variant, SirA(P141T) , remained functional in regard to inhibiting …
By analyzing loss-of-function variants of both SirA and DnaA, we observe that SirA's ability to inhibit DNA replication can be …