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2019 40
2020 178
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Emergence of a Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2: Biology and Therapeutic Options.
Khan S, Siddique R, Shereen MA, Ali A, Liu J, Bai Q, Bashir N, Xue M. Khan S, et al. J Clin Microbiol. 2020 Apr 23;58(5):e00187-20. doi: 10.1128/JCM.00187-20. Print 2020 Apr 23. J Clin Microbiol. 2020. PMID: 32161092 Free PMC article. Review.
The new decade of the 21(st) century (2020) started with the emergence of a novel coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease (COVID-19) in Wuhan, China. It is the third highly pathogenic and transmissible coronavi
The new decade of the 21(st) century (2020) started with the emergence of a novel coronavirus known as SARS-CoV-2 that caused …
Updated Approaches against SARS-CoV-2.
Li H, Zhou Y, Zhang M, Wang H, Zhao Q, Liu J. Li H, et al. Antimicrob Agents Chemother. 2020 May 21;64(6):e00483-20. doi: 10.1128/AAC.00483-20. Print 2020 May 21. Antimicrob Agents Chemother. 2020. PMID: 32205349 Free PMC article. Review.
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). ...
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus dise
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.
Wan Y, Shang J, Graham R, Baric RS, Li F. Wan Y, et al. J Virol. 2020 Mar 17;94(7):e00127-20. doi: 10.1128/JVI.00127-20. Print 2020 Mar 17. J Virol. 2020. PMID: 31996437 Free PMC article.
Recently, a novel coronavirus (2019-nCoV) has emerged from Wuhan, China, causing symptoms in humans similar to those caused by severe acute respiratory syndrome coronavirus (SARS-CoV). ...Second, several critical residues in 2019-nCoV RBM (parti …
Recently, a novel coronavirus (2019-nCoV) has emerged from Wuhan, China, causing symptoms in humans similar to t …
Compounds with Therapeutic Potential against Novel Respiratory 2019 Coronavirus.
Martinez MA. Martinez MA. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e00399-20. doi: 10.1128/AAC.00399-20. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32152082 Free PMC article. Review.
Currently, the expansion of the novel human respiratory coronavirus (known as SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2], COVID-2019 [coronavirus disease 2019], or 2019-nCoV [2019 novel coronavirus]) has stressed …
Currently, the expansion of the novel human respiratory coronavirus (known as SARS-CoV-2 [severe acute respiratory synd …
Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens.
Chan JF, Yip CC, To KK, Tang TH, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tsoi HW, Choi GK, Tam AR, Cheng VC, Chan KH, Tsang OT, Yuen KY. Chan JF, et al. J Clin Microbiol. 2020 Apr 23;58(5):e00310-20. doi: 10.1128/JCM.00310-20. Print 2020 Apr 23. J Clin Microbiol. 2020. PMID: 32132196 Free PMC article.
On 31 December 2019, the World Health Organization was informed of a cluster of cases of pneumonia of unknown etiology in Wuhan, China. Subsequent investigations identified a novel coronavirus, now named severe acute respiratory syndrome coronavirus 2 …
On 31 December 2019, the World Health Organization was informed of a cluster of cases of pneumonia of unknown etiology in Wuhan, Chin …
COVID-19: Knowns, Unknowns, and Questions.
Weston S, Frieman MB. Weston S, et al. mSphere. 2020 Mar 18;5(2):e00203-20. doi: 10.1128/mSphere.00203-20. mSphere. 2020. PMID: 32188753 Free PMC article.
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the Hubei province in China in late 2019 demonstrates the epidemic potential of coronaviruses. ...We highlight the current state of knowledge of coronavirus biology while answe …
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the Hubei province in China in late 2019 de …
Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry.
Wan Y, Shang J, Sun S, Tai W, Chen J, Geng Q, He L, Chen Y, Wu J, Shi Z, Zhou Y, Du L, Li F. Wan Y, et al. J Virol. 2020 Feb 14;94(5):e02015-19. doi: 10.1128/JVI.02015-19. Print 2020 Feb 14. J Virol. 2020. PMID: 31826992 Free PMC article.
Coronavirus spike protein mediates viral entry into cells by first binding to a receptor on the host cell surface and then fusing viral and host membranes. ...Our study reveals a novel molecular mechanism for antibody-enhanced viral entry and can guide future vaccin
Coronavirus spike protein mediates viral entry into cells by first binding to a receptor on the host cell surface and then fusing vir
Laboratory Diagnosis of COVID-19: Current Issues and Challenges.
Tang YW, Schmitz JE, Persing DH, Stratton CW. Tang YW, et al. J Clin Microbiol. 2020 May 26;58(6):e00512-20. doi: 10.1128/JCM.00512-20. Print 2020 May 26. J Clin Microbiol. 2020. PMID: 32245835 Free PMC article.
This commentary covers current issues and challenges for the laboratory diagnosis of infections caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ...
This commentary covers current issues and challenges for the laboratory diagnosis of infections caused by severe acute respiratory syndrome …
COVID-19: an Immunopathological View.
Kadkhoda K. Kadkhoda K. mSphere. 2020 Apr 22;5(2):e00344-20. doi: 10.1128/mSphere.00344-20. mSphere. 2020. PMID: 32321823 Free PMC article. Review.
Since its emergence in December 2019, it took only a couple of months for an outbreak of the novel coronavirus disease 2019 (COVID-19) to be declared a pandemic by the World Health Organization (WHO). This along with the highly infectious nature of the disease and t …
Since its emergence in December 2019, it took only a couple of months for an outbreak of the novel coronavirus disease 2019 (C …
TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection.
Iwata-Yoshikawa N, Okamura T, Shimizu Y, Hasegawa H, Takeda M, Nagata N. Iwata-Yoshikawa N, et al. J Virol. 2019 Mar 5;93(6):e01815-18. doi: 10.1128/JVI.01815-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30626688 Free PMC article.
Transmembrane serine protease TMPRSS2 activates the spike protein of highly pathogenic human coronaviruses such as severe acute respiratory syndrome-related coronavirus (SARS-CoV) and Middle East respiratory syndrome-related coronavirus (MERS-CoV). ...Taken t …
Transmembrane serine protease TMPRSS2 activates the spike protein of highly pathogenic human coronaviruses such as severe acute respi …
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