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Dissecting the mechanisms of cell division.
Ong JY, Torres JZ. Ong JY, et al. J Biol Chem. 2019 Jul 26;294(30):11382-11390. doi: 10.1074/jbc.AW119.008149. Epub 2019 Jun 7. J Biol Chem. 2019. PMID: 31175154 Free PMC article. Review.
Cell division is a highly regulated and carefully orchestrated process. Understanding the mechanisms that promote proper cell division is an important step toward unraveling important questions in cell biology and human health. Early studies seeking to dissect the …
Cell division is a highly regulated and carefully orchestrated process. Understanding the mechanisms that promote proper cell divisio …
Dissecting the role of conformational change and membrane binding by the bacterial cell division regulator MinE in the stimulation of MinD ATPase activity.
Ayed SH, Cloutier AD, McLeod LJ, Foo ACY, Damry AM, Goto NK. Ayed SH, et al. J Biol Chem. 2017 Dec 15;292(50):20732-20743. doi: 10.1074/jbc.M117.805945. Epub 2017 Oct 24. J Biol Chem. 2017. PMID: 29066619 Free PMC article.
This domain is buried in the 6-beta-stranded MinE "closed" structure, but is liberated for interactions with MinD, giving rise to a 4-beta-stranded "open" structure through an unknown mechanism. Here we show that MinE-membrane interactions induce a structural change into a …
This domain is buried in the 6-beta-stranded MinE "closed" structure, but is liberated for interactions with MinD, giving rise to a 4-beta-s …