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2004 1
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2022 51
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485 results
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Page 1
Galectin-3 in Cardiovascular Diseases.
Blanda V, Bracale UM, Di Taranto MD, Fortunato G. Blanda V, et al. Int J Mol Sci. 2020 Dec 3;21(23):9232. doi: 10.3390/ijms21239232. Int J Mol Sci. 2020. PMID: 33287402 Free PMC article. Review.
We report the biological role and molecular mechanisms of Gal-3 in other CVDs, highlighting its involvement in the development of cardiac fibrosis and impaired myocardium remodelling, resulting in heart failure and atrial fibrillation. ...Finally, we report t …
We report the biological role and molecular mechanisms of Gal-3 in other CVDs, highlighting its involvement in the development of …
CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation.
Martínez-Martínez E, Brugnolaro C, Ibarrola J, Ravassa S, Buonafine M, López B, Fernández-Celis A, Querejeta R, Santamaria E, Fernández-Irigoyen J, Rábago G, Moreno MU, Jaisser F, Díez J, González A, López-Andrés N. Martínez-Martínez E, et al. Hypertension. 2019 Mar;73(3):602-611. doi: 10.1161/HYPERTENSIONAHA.118.11874. Hypertension. 2019. PMID: 30612490
Myocardial fibrosis is a main contributor to the development of heart failure (HF). CT-1 (cardiotrophin-1) and Gal-3 (galectin-3) are increased in HF and associated with myocardial fibrosis. ...Male Wistar rats and B6CBAF1 mice treated with CT-1 (20 g/ …
Myocardial fibrosis is a main contributor to the development of heart failure (HF). CT-1 (cardiotrophin-1) and Gal-3 (galec …
The Role of Biomarkers in Cardio-Oncology.
Ananthan K, Lyon AR. Ananthan K, et al. J Cardiovasc Transl Res. 2020 Jun;13(3):431-450. doi: 10.1007/s12265-020-10042-3. Epub 2020 Jul 8. J Cardiovasc Transl Res. 2020. PMID: 32642841 Free PMC article. Review.
In the field of cardio-oncology, it is well recognised that despite the benefits of chemotherapy in treating and possibly curing cancer, it can cause catastrophic damage to bystander tissues resulting in a range of potentially of life-threatening cardiovascular toxicities, and le …
In the field of cardio-oncology, it is well recognised that despite the benefits of chemotherapy in treating and possibly curing cancer, it …
Cardiac biomarkers of heart failure in chronic kidney disease.
Han X, Zhang S, Chen Z, Adhikari BK, Zhang Y, Zhang J, Sun J, Wang Y. Han X, et al. Clin Chim Acta. 2020 Nov;510:298-310. doi: 10.1016/j.cca.2020.07.040. Epub 2020 Jul 23. Clin Chim Acta. 2020. PMID: 32710942 Review.
Heart failure remains a continuing threat to patients with chronic kidney disease (CKD). ...In this review, the major four groups of heart failure biomarkers are explored. These include those associated with: myocardial stretch, ie, brain natriuretic peptide (BNP), …
Heart failure remains a continuing threat to patients with chronic kidney disease (CKD). ...In this review, the major four groups of …
Adverse Cardiac Remodelling after Acute Myocardial Infarction: Old and New Biomarkers.
Berezin AE, Berezin AA. Berezin AE, et al. Dis Markers. 2020 Jun 12;2020:1215802. doi: 10.1155/2020/1215802. eCollection 2020. Dis Markers. 2020. PMID: 32626540 Free PMC article. Review.
Numerous studies have examined the diagnostic and prognostic potencies of circulating cardiac biomarkers in acute coronary syndrome/AMI and heart failure after AMI, and even fewer have depicted the utility of biomarkers in AMI patients undergoing primary PCI. ...Cli …
Numerous studies have examined the diagnostic and prognostic potencies of circulating cardiac biomarkers in acute coronary syndrome/A …
NETosis as a Pathogenic Factor for Heart Failure.
Ling S, Xu JW. Ling S, et al. Oxid Med Cell Longev. 2021 Feb 23;2021:6687096. doi: 10.1155/2021/6687096. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 33680285 Free PMC article. Review.
Heart failure, especially heart failure with preserved ejection fraction, is closely related to systemic and local cardiac persistent chronic low-grade aseptic inflammation, microvascular damage characterized by endothelial dysfunction, oxidative stress, myoc …
Heart failure, especially heart failure with preserved ejection fraction, is closely related to systemic and local cardiac …
Novel biomarkers of cardiovascular disease: Applications in clinical practice.
Lyngbakken MN, Myhre PL, Røsjø H, Omland T. Lyngbakken MN, et al. Crit Rev Clin Lab Sci. 2019 Jan;56(1):33-60. doi: 10.1080/10408363.2018.1525335. Epub 2018 Nov 20. Crit Rev Clin Lab Sci. 2019. PMID: 30457415 Review.
The most widely used contemporary cardiovascular biomarkers are the natriuretic peptides in the diagnosis and prognosis of heart failure and cardiac troponins in the diagnosis of acute myocardial infarction. ...We will then discuss the biomarkers according to main g …
The most widely used contemporary cardiovascular biomarkers are the natriuretic peptides in the diagnosis and prognosis of heart fail …
The Diagnostic and Therapeutic Potential of Galectin-3 in Cardiovascular Diseases.
Sygitowicz G, Maciejak-Jastrzębska A, Sitkiewicz D. Sygitowicz G, et al. Biomolecules. 2021 Dec 29;12(1):46. doi: 10.3390/biom12010046. Biomolecules. 2021. PMID: 35053194 Free PMC article. Review.
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the development of many disease conditions, including heart disease. Galectin-3, a regulatory protein, is elevated in both acute and chronic heart failur …
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the development of many disease condition …
Obesity, Galectin-3, and Incident Heart Failure: The ARIC Study.
Florido R, Kwak L, Echouffo-Tcheugui JB, Zhang S, Michos ED, Nambi V, Goldberg RB, Hoogeveen RC, Lazo M, Gerstenblith G, Post WS, Blumenthal RS, Coresh J, Folsom AR, Selvin E, Ballantyne C, Ndumele CE. Florido R, et al. J Am Heart Assoc. 2022 May 3;11(9):e023238. doi: 10.1161/JAHA.121.023238. Epub 2022 May 2. J Am Heart Assoc. 2022. PMID: 35491999 Free PMC article.
Background Laboratory data suggest obesity is linked to myocardial inflammation and fibrosis, but clinical data are limited. We aimed to examine the association of obesity with galectin-3, a biomarker of cardiac inflammation and fibrosis, and the related impl …
Background Laboratory data suggest obesity is linked to myocardial inflammation and fibrosis, but clinical data are limited. We aimed to exa …
Galectin-3-centered paracrine network mediates cardiac inflammation and fibrosis upon β-adrenergic insult.
Hu G, Wu J, Gu H, Deng X, Xu W, Feng S, Wang S, Song Y, Pang Z, Deng X, Vendrov AE, Madamanchi NR, Runge MS, Wang X, Zhang Y, Xiao H, Dong E. Hu G, et al. Sci China Life Sci. 2022 Nov 22. doi: 10.1007/s11427-022-2189-x. Online ahead of print. Sci China Life Sci. 2022. PMID: 36449214
In the heart of mice treated with beta-AR agonist isoproterenol (ISO, 5 mg kg(-1)), galectin-3 expression was upregulated markedly later than IL-18 activation, and Nlrp3(-/-) and Il18(-/-) mice did not show ISO-induced galectin-3 upregulation. . …
In the heart of mice treated with beta-AR agonist isoproterenol (ISO, 5 mg kg(-1)), galectin-3 expression was upregulat …
485 results