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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2007 1
2008 3
2009 3
2010 6
2011 10
2012 15
2013 18
2014 46
2015 52
2016 52
2017 44
2018 58
2019 53
2020 72
2021 10
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381 results
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CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation.
Martínez-Martínez E, Brugnolaro C, Ibarrola J, Ravassa S, Buonafine M, López B, Fernández-Celis A, Querejeta R, Santamaria E, Fernández-Irigoyen J, Rábago G, Moreno MU, Jaisser F, Díez J, González A, López-Andrés N. Martínez-Martínez E, et al. Hypertension. 2019 Mar;73(3):602-611. doi: 10.1161/HYPERTENSIONAHA.118.11874. Hypertension. 2019. PMID: 30612490
Myocardial fibrosis is a main contributor to the development of heart failure (HF). CT-1 (cardiotrophin-1) and Gal-3 (galectin-3) are increased in HF and associated with myocardial fibrosis. ...Male Wistar rats and B6CBAF1 mice treated with CT-1 (20 g/ …
Myocardial fibrosis is a main contributor to the development of heart failure (HF). CT-1 (cardiotrophin-1) and Gal-3 (galec …
Galectin-3 in Heart Failure: An Update of the Last 3 Years.
Gehlken C, Suthahar N, Meijers WC, de Boer RA. Gehlken C, et al. Heart Fail Clin. 2018 Jan;14(1):75-92. doi: 10.1016/j.hfc.2017.08.009. Heart Fail Clin. 2018. PMID: 29153203 Review.
Experimental research has shown that galectin-3 directly induces pathologic remodeling of the heart, and is therefore considered a culprit protein in the development of cardiac fibrosis in HF, with potentially relevant clinical implications. In summary …
Experimental research has shown that galectin-3 directly induces pathologic remodeling of the heart, and is therefore c …
Acute Kidney Injury Induces Remote Cardiac Damage and Dysfunction Through the Galectin-3 Pathway.
Prud'homme M, Coutrot M, Michel T, Boutin L, Genest M, Poirier F, Launay JM, Kane B, Kinugasa S, Prakoura N, Vandermeersch S, Cohen-Solal A, Delcayre C, Samuel JL, Mehta R, Gayat E, Mebazaa A, Chadjichristos CE, Legrand M. Prud'homme M, et al. JACC Basic Transl Sci. 2019 Oct 28;4(6):717-732. doi: 10.1016/j.jacbts.2019.06.005. eCollection 2019 Oct. JACC Basic Transl Sci. 2019. PMID: 31709320 Free PMC article.
Acute kidney injury is associated with increased risk of heart failure and mortality. This study demonstrates that acute kidney injury induces remote cardiac dysfunction, damage, injury, and fibrosis via a galectin-3 (Gal-3) dependent pathway. G …
Acute kidney injury is associated with increased risk of heart failure and mortality. This study demonstrates that acute kidney injur …
The role of galectin-3 in heart failure and cardiovascular disease.
Zhong X, Qian X, Chen G, Song X. Zhong X, et al. Clin Exp Pharmacol Physiol. 2019 Mar;46(3):197-203. doi: 10.1111/1440-1681.13048. Epub 2019 Jan 7. Clin Exp Pharmacol Physiol. 2019. PMID: 30372548 Review.
Galectin-3, a beta-galactoside-binding lectin, is a new important player in the progression of heart failure (HF) and is also linked to poor outcome in patients with cardiovascular disease. Genetic or pharmacological inhibition of galectin-3 slo …
Galectin-3, a beta-galactoside-binding lectin, is a new important player in the progression of heart failure (HF) and i …
Galectin-3 and Arterial Stiffness in Patients with Heart Failure: A Pilot Study.
Oikonomou E, Karlis D, Tsalamadris S, Siasos G, Chrysohoou C, Vogiatzi G, Dimitropoulos S, Charalambous G, Kouskouni E, Tousoulis D. Oikonomou E, et al. Curr Vasc Pharmacol. 2019;17(4):396-400. doi: 10.2174/1570161116666180703094919. Curr Vasc Pharmacol. 2019. PMID: 29968538
BACKGROUND: Cardiac performance depends on optimum ventriculoarterial coupling which is impaired in patients with heart failure (HF). ...There was a significant association of galectin-3 levels with PWV (r=0.37, p=0.03) and patients with PWV above medi …
BACKGROUND: Cardiac performance depends on optimum ventriculoarterial coupling which is impaired in patients with heart failur …
Association of plasma-soluble ST2 and galectin-3 with cardiovascular events and mortality following cardiac surgery.
Patel DM, Thiessen-Philbrook H, Brown JR, McArthur E, Moledina DG, Mansour SG, Shlipak MG, Koyner JL, Kavsak P, Whitlock RP, Everett AD, Malenka DJ, Garg AX, Coca SG, Parikh CR. Patel DM, et al. Am Heart J. 2020 Feb;220:253-263. doi: 10.1016/j.ahj.2019.11.014. Epub 2019 Dec 3. Am Heart J. 2020. PMID: 31911262
Soluble suppression of tumorigenicity 2 (sST2) and galectin-3 (gal-3) are biomarkers of myocardial remodeling and fibrosis; however, their potential association with post-operative changes is unknown. METHODS: We measured peri-operative plasma sST2 and gal- …
Soluble suppression of tumorigenicity 2 (sST2) and galectin-3 (gal-3) are biomarkers of myocardial remodeling and fibro …
Galectin-3 in patients with coronary heart disease and atrial fibrillation.
Kang Q, Li X, Yang M, Fernando T, Wan Z. Kang Q, et al. Clin Chim Acta. 2018 Mar;478:166-170. doi: 10.1016/j.cca.2017.12.041. Epub 2017 Dec 27. Clin Chim Acta. 2018. PMID: 29287900
OBJECTIVE: To observe the change of the inflammatory factor Galectin-3 in patients with coronary heart disease, and the correlation between Galectin-3 and the severity of the disease. ...ELISA technique was equipped to observe the Galectin …
OBJECTIVE: To observe the change of the inflammatory factor Galectin-3 in patients with coronary heart disease, and the …
Galectin-3 predicts response and outcomes after cardiac resynchronization therapy.
Andre C, Piver E, Perault R, Bisson A, Pucheux J, Vermes E, Pierre B, Fauchier L, Babuty D, Clementy N. Andre C, et al. J Transl Med. 2018 Nov 3;16(1):299. doi: 10.1186/s12967-018-1675-4. J Transl Med. 2018. PMID: 30390680 Free PMC article.
At 48 months of follow-up, 12 patients had been hospitalized for a major cardiovascular event or had died. Galectin-3 level predicted long-term outcomes (HR = 3.31 [1.00-11.34], p = 0.05). CONCLUSIONS: Gal-3 serum level predicts the response to CRT at …
At 48 months of follow-up, 12 patients had been hospitalized for a major cardiovascular event or had died. Galectin-3 level pr …
Biomarkers in heart failure: the past, current and future.
Sarhene M, Wang Y, Wei J, Huang Y, Li M, Li L, Acheampong E, Zhengcan Z, Xiaoyan Q, Yunsheng X, Jingyuan M, Xiumei G, Guanwei F. Sarhene M, et al. Heart Fail Rev. 2019 Nov;24(6):867-903. doi: 10.1007/s10741-019-09807-z. Heart Fail Rev. 2019. PMID: 31183637 Review.
Despite the enhanced knowledge of the pathophysiology of heart failure (HF), it still remains a serious syndrome with substantial morbidity, mortality, and frequent hospitalizations. ...Following the recommendation of natriuretic peptides (B-type natriuretic peptide and N- …
Despite the enhanced knowledge of the pathophysiology of heart failure (HF), it still remains a serious syndrome with substantial mor …
Role of oxidative stress-related biomarkers in heart failure: galectin 3, alpha1-antitrypsin and LOX-1: new therapeutic perspective?
Lubrano V, Balzan S. Lubrano V, et al. Mol Cell Biochem. 2020 Jan;464(1-2):143-152. doi: 10.1007/s11010-019-03656-y. Epub 2019 Nov 29. Mol Cell Biochem. 2020. PMID: 31782085 Review.
The up-regulation of galectin-3 appears to be associated with HF, atrial fibrillation, dilated cardiomyopathy, fibrogenesis and mortality, while in other cases it seems that galectin-3 may be protective in ischaemia-reperfusion injury. ...In conclusion …
The up-regulation of galectin-3 appears to be associated with HF, atrial fibrillation, dilated cardiomyopathy, fibrogenesis an …
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