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Year Number of Results
2017 4
2018 1
2019 6
2020 17
2021 15
2022 10
2023 23
2024 16
2025 21
2026 22

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123 results

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Page 1
Immune-Related Adverse Events (irAEs): Diagnosis, Management, and Clinical Pearls.
Darnell EP, Mooradian MJ, Baruch EN, Yilmaz M, Reynolds KL. Darnell EP, et al. Curr Oncol Rep. 2020 Mar 21;22(4):39. doi: 10.1007/s11912-020-0897-9. Curr Oncol Rep. 2020. PMID: 32200442 Review.
PURPOSE OF REVIEW: While immune checkpoint inhibitor (ICI) therapy has improved melanoma patient outcomes, it has also resulted in the rise of unique immune-related adverse events (irAEs). ...Keeping up with the evolving field of immunotherapy and rela …
PURPOSE OF REVIEW: While immune checkpoint inhibitor (ICI) therapy has improved melanoma patient outcomes, it ha …
Corticosteroid-resistant immune-related adverse events: a systematic review.
Daetwyler E, Wallrabenstein T, König D, Cappelli LC, Naidoo J, Zippelius A, Läubli H. Daetwyler E, et al. J Immunother Cancer. 2024 Jan 17;12(1):e007409. doi: 10.1136/jitc-2023-007409. J Immunother Cancer. 2024. PMID: 38233099 Free PMC article.
Immune checkpoint inhibitor (ICI) treatment has become an important therapeutic option for various cancer types. ...Most publications investigated sr colitis (n=26), followed by hepatitis (n=21), pneumonitis (n=17) and myocarditis (n=15). There …
Immune checkpoint inhibitor (ICI) treatment has become an important therapeutic option for various cancer types. …
Immune-Mediated Liver Injury From Checkpoint Inhibitor: An Evolving Frontier With Emerging Challenges.
Dara L, De Martin E. Dara L, et al. Liver Int. 2025 Feb;45(2):e16198. doi: 10.1111/liv.16198. Liver Int. 2025. PMID: 39868913 Free PMC article. Review.
Over the past decade, immune checkpoint inhibitors (ICIs) have transformed the treatment of cancer, though they come with the risk of immune-related adverse (irAEs) events such as hepatotoxicity or Immune-mediated Liver Injury from Checkpoint Inhibitors (ILICI). ILI …
Over the past decade, immune checkpoint inhibitors (ICIs) have transformed the treatment of cancer, though they come with the risk of immune …
Steroid-refractory immune checkpoint inhibitor (ICI) hepatitis and ICI rechallenge: A systematic review and meta-analysis.
Hwang SY, Hsieh P, Zhang W. Hwang SY, et al. Hepatol Commun. 2024 Sep 18;8(10):e0525. doi: 10.1097/HC9.0000000000000525. eCollection 2024 Oct 1. Hepatol Commun. 2024. PMID: 39298568 Free PMC article.
However, this has also resulted in the emergence of immune-related adverse events, notably ICI hepatitis, posing a significant clinical challenge. While steroids are the primary treatment, there are increasing cases of steroid-refractory ICI hepatit …
However, this has also resulted in the emergence of immune-related adverse events, notably ICI hepatitis, posing a significant …
Hepatobiliary Adverse Events.
Abu-Sbeih H, Wang Y. Abu-Sbeih H, et al. Adv Exp Med Biol. 2020;1244:271-276. doi: 10.1007/978-3-030-41008-7_14. Adv Exp Med Biol. 2020. PMID: 32301021 Review.
The diagnosis of ICI-induced hepatitis is made after exclusion of other etiologies based on medical history, laboratory evaluation, and imaging and histological findings. Treatment of ICI-induced hepatitis consists of ICI discontinuation and …
The diagnosis of ICI-induced hepatitis is made after exclusion of other etiologies based on medical history, laboratory evalua …
Immune checkpoint inhibitor-related hepatotoxicity: A review.
Remash D, Prince DS, McKenzie C, Strasser SI, Kao S, Liu K. Remash D, et al. World J Gastroenterol. 2021 Aug 28;27(32):5376-5391. doi: 10.3748/wjg.v27.i32.5376. World J Gastroenterol. 2021. PMID: 34539139 Free PMC article. Review.
With this increased use, adverse events including immune checkpoint inhibitor-related hepatotoxicity (ICH) have emerged as an important clinical problem. ...The incidence of ICH varies between 1%-20% depending on the number, type and dose of ICI receiv …
With this increased use, adverse events including immune checkpoint inhibitor-related hepatotoxicity (ICH) have emerged …
Checkpoint inhibitor-induced hepatotoxicity: Role of liver biopsy and management approach.
Bessone F, Bjornsson ES. Bessone F, et al. World J Hepatol. 2022 Jul 27;14(7):1269-1276. doi: 10.4254/wjh.v14.i7.1269. World J Hepatol. 2022. PMID: 36158917 Free PMC article.
The liver injury is characterized by hepatocellular injury resembling autoimmune hepatitis biochemically but not immunologically as patients with ICI induced hepatoxicity rarely have auto-antibodies or IgG elevation. ...Recently it has shown that initi …
The liver injury is characterized by hepatocellular injury resembling autoimmune hepatitis biochemically but not immuno …
Immunotherapy and Gastrointestinal Toxicities.
Simand PF, Baudoux N, Kössler T. Simand PF, et al. Praxis (Bern 1994). 2023;112(3):172-177. doi: 10.1024/1661-8157/a003977. Praxis (Bern 1994). 2023. PMID: 36855888
Because in some instances this can be severe or fatal, it is essential to be able to identify immune-related adverse events rapidly. Prompt initiation of systemic immunosuppression can improve outcomes. A biopsy is often necessary to confirm the diagnosis of immune-related …
Because in some instances this can be severe or fatal, it is essential to be able to identify immune-related adverse events rapidly. Prompt …
Immune Checkpoint Inhibitor-induced Fanconi Syndrome.
Farid S, Latif H, Nilubol C, Kim C. Farid S, et al. Cureus. 2020 Apr 16;12(4):e7686. doi: 10.7759/cureus.7686. Cureus. 2020. PMID: 32431966 Free PMC article.
Immune-related adverse events (irAEs) are potential side effects that can arise during or after treatment with ICI therapy. We describe a case of ICI-induced Fanconi syndrome in a 58-year-old man with extensive-stage small-cell lung cancer (ES-SCLC), who had disease …
Immune-related adverse events (irAEs) are potential side effects that can arise during or after treatment with ICI therapy. We descri …
The Current status of steroid-refractory immune-checkpoint-inhibitor-related hepatotoxicity.
Xing H, Wang Y, Qu B, Wei Q, Li C, Pan C, Li H. Xing H, et al. Transl Oncol. 2023 Feb;28:101619. doi: 10.1016/j.tranon.2023.101619. Epub 2023 Jan 7. Transl Oncol. 2023. PMID: 36623392 Free PMC article. Review.
ICI-related hepatotoxicity (IRH) is becoming more and more common as immune checkpoint inhibitors (ICIs) have begun to be increasingly approved and used in combination with other anti-tumor drugs worldwide. Steroids are the first choice for the treatment of IRH, but the su …
ICI-related hepatotoxicity (IRH) is becoming more and more common as immune checkpoint inhibitors (ICIs) have begun to be increasingl …
123 results