Monoclonal and oligoclonal anti-platelet factor 4 antibodies mediate VITT.
Kanack AJ, Bayas A, George G, Abou-Ismail MY, Singh B, Kohlhagen MC, Splinter NP, Christ M, Naumann M, Moser KA, Smock KJ, Grazioli A, Wen R, Wang D, Murray DL, Padmanabhan A.
Kanack AJ, et al.
Blood. 2022 Jul 7;140(1):73-77. doi: 10.1182/blood.2021014588.
Blood. 2022.
PMID: 35560046
Free PMC article.
Kanack and colleagues analyze anti-platelet factor 4 antibodies from 5 patients with vaccine-induced thrombotic thrombocytopenia (VITT) secondary to COVID-19 adenoviral vaccination and antibodies from patients with spontaneous heparin-induced thrombocytopenia (HIT) …
Kanack and colleagues analyze anti-platelet factor 4 antibodies from 5 patients with vaccine-induced thrombotic thrombocytopenia (VIT …