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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1964 1
1966 1
1972 2
1973 2
1974 2
1975 1
1976 1
1979 2
1981 1
1982 1
1986 2
1988 1
1990 1
1992 3
1993 4
1994 12
1996 2
1997 5
1998 3
1999 4
2000 3
2001 13
2002 7
2003 10
2004 5
2005 11
2006 23
2007 31
2008 23
2009 35
2010 38
2011 33
2012 29
2013 29
2014 32
2015 53
2016 38
2017 43
2018 32
2019 19
2020 17
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Search Results

511 results
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Page 1
Imaging biomarker roadmap for cancer studies.
O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, deSouza NM, Dickson JC, Dive C, Evelhoch JL, Faivre-Finn C, Gallagher FA, Gilbert FJ, Gillies RJ, Goh V, Griffiths JR, Groves AM, Halligan S, Harris AL, Hawkes DJ, Hoekstra OS, Huang EP, Hutton BF, Jackson EF, Jayson GC, Jones A, Koh DM, Lacombe D, Lambin P, Lassau N, Leach MO, Lee TY, Leen EL, Lewis JS, Liu Y, Lythgoe MF, Manoharan P, Maxwell RJ, Miles KA, Morgan B, Morris S, Ng T, Padhani AR, Parker GJ, Partridge M, Pathak AP, Peet AC, Punwani S, Reynolds AR, Robinson SP, Shankar LK, Sharma RA, Soloviev D, Stroobants S, Sullivan DC, Taylor SA, Tofts PS, Tozer GM, van Herk M, Walker-Samuel S, Wason J, Williams KJ, Workman P, Yankeelov TE, Brindle KM, McShane LM, Jackson A, Waterton JC. O'Connor JP, et al. Among authors: Lambin P. Nat Rev Clin Oncol. 2017 Mar;14(3):169-186. doi: 10.1038/nrclinonc.2016.162. Epub 2016 Oct 11. Nat Rev Clin Oncol. 2017. PMID: 27725679 Free PMC article. Review.
Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs used daily in oncology include clinical TNM stage, objective response and left ventricular ejection fraction. ...Recognizing this need, Cancer Research UK (CRUK) and the Eur …
Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs used daily in oncology include clinical …
Radiomics: the bridge between medical imaging and personalized medicine.
Lambin P, Leijenaar RTH, Deist TM, Peerlings J, de Jong EEC, van Timmeren J, Sanduleanu S, Larue RTHM, Even AJG, Jochems A, van Wijk Y, Woodruff H, van Soest J, Lustberg T, Roelofs E, van Elmpt W, Dekker A, Mottaghy FM, Wildberger JE, Walsh S. Lambin P, et al. Nat Rev Clin Oncol. 2017 Dec;14(12):749-762. doi: 10.1038/nrclinonc.2017.141. Epub 2017 Oct 4. Nat Rev Clin Oncol. 2017. PMID: 28975929 Review.
Radiomics, the high-throughput mining of quantitative image features from standard-of-care medical imaging that enables data to be extracted and applied within clinical-decision support systems to improve diagnostic, prognostic, and predictive accuracy, is gaining importance in …
Radiomics, the high-throughput mining of quantitative image features from standard-of-care medical imaging that enables data to be extracted …
Combining radiotherapy with immunotherapy: the past, the present and the future.
Van Limbergen EJ, De Ruysscher DK, Olivo Pimentel V, Marcus D, Berbee M, Hoeben A, Rekers N, Theys J, Yaromina A, Dubois LJ, Lambin P. Van Limbergen EJ, et al. Among authors: Lambin P. Br J Radiol. 2017 Aug;90(1076):20170157. doi: 10.1259/bjr.20170157. Epub 2017 May 25. Br J Radiol. 2017. PMID: 28541096 Free PMC article. Review.
The advent of immunotherapy is currently revolutionizing the field of oncology, where different drugs are used to stimulate different steps in a failing cancer immune response chain. This review gives a basic overview of the immune response against cancer, as well a …
The advent of immunotherapy is currently revolutionizing the field of oncology, where different drugs are used to stimulate different steps …
Machine Learning methods for Quantitative Radiomic Biomarkers.
Parmar C, Grossmann P, Bussink J, Lambin P, Aerts HJWL. Parmar C, et al. Among authors: Lambin P. Sci Rep. 2015 Aug 17;5:13087. doi: 10.1038/srep13087. Sci Rep. 2015. PMID: 26278466 Free PMC article.
Radiomics extracts and mines large number of medical imaging features quantifying tumor phenotypic characteristics. Highly accurate and reliable machine-learning approaches can drive the success of radiomic applications in clinical care. ...A total of 440 radiomic features …
Radiomics extracts and mines large number of medical imaging features quantifying tumor phenotypic characteristics. Highly accurate a …
Targeting Hypoxia to Improve Non-Small Cell Lung Cancer Outcome.
Salem A, Asselin MC, Reymen B, Jackson A, Lambin P, West CML, O'Connor JPB, Faivre-Finn C. Salem A, et al. Among authors: Lambin P. J Natl Cancer Inst. 2018 Jan 1;110(1). doi: 10.1093/jnci/djx160. J Natl Cancer Inst. 2018. PMID: 28922791 Review.
Oxygen deprivation (hypoxia) in non-small cell lung cancer (NSCLC) is an important factor in treatment resistance and poor survival. ...Although this review will focus on NSCLC hypoxia, more general discussions (eg, obstacles of hypoxia biomarker resea …
Oxygen deprivation (hypoxia) in non-small cell lung cancer (NSCLC) is an important factor in treatment resistance and poor sur …
Hypoxia and hypoxia response-associated molecular markers in esophageal cancer: A systematic review.
Peerlings J, Van De Voorde L, Mitea C, Larue R, Yaromina A, Sandeleanu S, Spiegelberg L, Dubois L, Lambin P, Mottaghy FM. Peerlings J, et al. Among authors: Lambin P. Methods. 2017 Nov 1;130:51-62. doi: 10.1016/j.ymeth.2017.07.002. Epub 2017 Jul 10. Methods. 2017. PMID: 28705470 Review.
Promising non-invasive imaging-techniques have been suggested to assess tumor hypoxia and hypoxia-associated molecular responses. ...For personalized hypoxia-guided treatment, safe and reliable makers for tumor hypoxia are needed to selec …
Promising non-invasive imaging-techniques have been suggested to assess tumor hypoxia and hypoxia-associated molecular …
Nomograms for prediction of outcome with or without adjuvant radiation therapy for patients with endometrial cancer: a pooled analysis of PORTEC-1 and PORTEC-2 trials.
Creutzberg CL, van Stiphout RG, Nout RA, Lutgens LC, Jürgenliemk-Schulz IM, Jobsen JJ, Smit VT, Lambin P. Creutzberg CL, et al. Among authors: Lambin P. Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):530-9. doi: 10.1016/j.ijrobp.2014.11.022. Epub 2015 Jan 30. Int J Radiat Oncol Biol Phys. 2015. PMID: 25680597 Clinical Trial.
BACKGROUND: Postoperative radiation therapy for stage I endometrial cancer improves locoregional control but is without survival benefit. ...Ranking of variables as to their predictive power showed that age, tumor grade, and LVSI were highly predictive for all outco …
BACKGROUND: Postoperative radiation therapy for stage I endometrial cancer improves locoregional control but is without survival bene …
How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models.
van Gisbergen MW, Voets AM, Starmans MH, de Coo IF, Yadak R, Hoffmann RF, Boutros PC, Smeets HJ, Dubois L, Lambin P. van Gisbergen MW, et al. Among authors: Lambin P. Mutat Res Rev Mutat Res. 2015 Apr-Jun;764:16-30. doi: 10.1016/j.mrrev.2015.01.001. Epub 2015 Jan 20. Mutat Res Rev Mutat Res. 2015. PMID: 26041263 Free article. Review.
Recently, studies have suggested an eminent role for mitochondrial DNA (mtDNA) mutations in the development of a wide variety of cancers. ...Pharmaceutical impairment of OXPHOS by metformin can increase the efficiency of radiotherapy. To study mitochondrial dysfunct …
Recently, studies have suggested an eminent role for mitochondrial DNA (mtDNA) mutations in the development of a wide variety of cancers
Tracking tumor biology with radiomics: A systematic review utilizing a radiomics quality score.
Sanduleanu S, Woodruff HC, de Jong EEC, van Timmeren JE, Jochems A, Dubois L, Lambin P. Sanduleanu S, et al. Among authors: Lambin P. Radiother Oncol. 2018 Jun;127(3):349-360. doi: 10.1016/j.radonc.2018.03.033. Epub 2018 May 18. Radiother Oncol. 2018. PMID: 29779918 Free article. Review.
Two authors (S.S, H.W) separately and two authors (J.v.T and E.d.J) concordantly scored the articles for their methodology and analyses according to the previously published radiomics quality score (RQS). ...The RQS scoring resulted in some discrepancies between the …
Two authors (S.S, H.W) separately and two authors (J.v.T and E.d.J) concordantly scored the articles for their methodology and …
Evaluation of tumour hypoxia during radiotherapy using [(18)F]HX4 PET imaging and blood biomarkers in patients with head and neck cancer.
Zegers CM, Hoebers FJ, van Elmpt W, Bons JA, Öllers MC, Troost EG, Eekers D, Balmaekers L, Arts-Pechtold M, Mottaghy FM, Lambin P. Zegers CM, et al. Among authors: Lambin P. Eur J Nucl Med Mol Imaging. 2016 Nov;43(12):2139-2146. doi: 10.1007/s00259-016-3429-y. Epub 2016 Jun 1. Eur J Nucl Med Mol Imaging. 2016. PMID: 27251643 Free PMC article. Clinical Trial.
BACKGROUND AND PURPOSE: Increased tumour hypoxia is associated with a worse overall survival in patients with head and neck squamous cell carcinoma (HNSCC). ...CONCLUSIONS: [(18)F]HX4-PET/CT imaging allows monitoring changes in hypoxia during (chemo)radiot
BACKGROUND AND PURPOSE: Increased tumour hypoxia is associated with a worse overall survival in patients with head and neck sq …
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