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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1964 2
1965 2
1968 1
1970 2
1971 1
1972 2
1973 5
1974 4
1975 5
1976 4
1977 6
1978 6
1979 8
1980 22
1981 44
1982 40
1983 56
1984 60
1985 62
1986 55
1987 50
1988 60
1989 70
1990 71
1991 70
1992 58
1993 82
1994 93
1995 111
1996 105
1997 104
1998 122
1999 154
2000 129
2001 153
2002 135
2003 161
2004 183
2005 204
2006 227
2007 260
2008 265
2009 283
2010 250
2011 302
2012 323
2013 370
2014 457
2015 454
2016 485
2017 443
2018 452
2019 348
2020 99
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6,963 results
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Page 1
Mutations and mechanisms in congenital and age-related cataracts.
Shiels A, Hejtmancik JF. Shiels A, et al. Exp Eye Res. 2017 Mar;156:95-102. doi: 10.1016/j.exer.2016.06.011. Epub 2016 Jun 19. Exp Eye Res. 2017. PMID: 27334249 Free PMC article. Review.
Loss of lens transparency, or cataract, is a frequently acquired cause of visual impairment in adults and may also present during childhood. ...Here, we briefly summarize current concepts pointing to differences in the molecular mechanisms underlying congenital and …
Loss of lens transparency, or cataract, is a frequently acquired cause of visual impairment in adults and may also present dur …
The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD.
Datta S, Cano M, Ebrahimi K, Wang L, Handa JT. Datta S, et al. Prog Retin Eye Res. 2017 Sep;60:201-218. doi: 10.1016/j.preteyeres.2017.03.002. Epub 2017 Mar 20. Prog Retin Eye Res. 2017. PMID: 28336424 Free PMC article. Review.
The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that interacts with photoreceptors on its apical side and with Bruch's membrane and the choriocapillaris on its basal side. ...This degeneration plays a central role in age- …
The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that interacts with photoreceptors on its apical side a …
Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema: Two-Year Results from a Comparative Effectiveness Randomized Clinical Trial.
Wells JA, Glassman AR, Ayala AR, Jampol LM, Bressler NM, Bressler SB, Brucker AJ, Ferris FL, Hampton GR, Jhaveri C, Melia M, Beck RW; Diabetic Retinopathy Clinical Research Network. Wells JA, et al. Ophthalmology. 2016 Jun;123(6):1351-9. doi: 10.1016/j.ophtha.2016.02.022. Epub 2016 Feb 27. Ophthalmology. 2016. PMID: 26935357 Free PMC article. Clinical Trial.
PARTICIPANTS: Six hundred sixty participants with visual acuity (VA) impairment from DME. METHODS: Randomization to 2.0-mg aflibercept, 1.25-mg repackaged (compounded) bevacizumab, or 0.3-mg ranibizumab intravitreous injections performed up to monthly using a protoc …
PARTICIPANTS: Six hundred sixty participants with visual acuity (VA) impairment from DME. METHODS: Randomization to 2.0-mg afl …
Age-related macular degeneration.
Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY. Lim LS, et al. Lancet. 2012 May 5;379(9827):1728-38. doi: 10.1016/S0140-6736(12)60282-7. Lancet. 2012. PMID: 22559899 Review.
Age-related macular degeneration is a major cause of blindness worldwide. With ageing populations in many countries, more than 20% might have the disorder. Advanced age-related macular degeneration, including neovascular
Age-related macular degeneration is a major cause of blindness worldwide. With ageing populations in many countr
Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss.
Ban N, Lee TJ, Sene A, Choudhary M, Lekwuwa M, Dong Z, Santeford A, Lin JB, Malek G, Ory DS, Apte RS. Ban N, et al. JCI Insight. 2018 Sep 6;3(17):e120824. doi: 10.1172/jci.insight.120824. eCollection 2018 Sep 6. JCI Insight. 2018. PMID: 30185655 Free PMC article.
Advanced age-related macular degeneration (AMD), the leading cause of blindness among people over 50 years of age, is characterized by atrophic neurodegeneration or pathologic angiogenesis. ...These mice also develop impaired dark adaptat …
Advanced age-related macular degeneration (AMD), the leading cause of blindness among people over 50 years of …
Effect of Adding Dexamethasone to Continued Ranibizumab Treatment in Patients With Persistent Diabetic Macular Edema: A DRCR Network Phase 2 Randomized Clinical Trial.
Maturi RK, Glassman AR, Liu D, Beck RW, Bhavsar AR, Bressler NM, Jampol LM, Melia M, Punjabi OS, Salehi-Had H, Sun JK; Diabetic Retinopathy Clinical Research Network. Maturi RK, et al. JAMA Ophthalmol. 2018 Jan 1;136(1):29-38. doi: 10.1001/jamaophthalmol.2017.4914. JAMA Ophthalmol. 2018. PMID: 29127949 Free PMC article. Clinical Trial.
IMPORTANCE: Some eyes have persistent diabetic macular edema (DME) following anti-vascular endothelial growth factor (anti-VEGF) therapy for DME. ...RESULTS: Of the 116 randomized patients, median age was 65 years (interquartile range [IQR], 58-71 years); 50.9% were …
IMPORTANCE: Some eyes have persistent diabetic macular edema (DME) following anti-vascular endothelial growth factor (anti-VEGF) ther …
The multifunctional choroid.
Nickla DL, Wallman J. Nickla DL, et al. Prog Retin Eye Res. 2010 Mar;29(2):144-68. doi: 10.1016/j.preteyeres.2009.12.002. Epub 2009 Dec 29. Prog Retin Eye Res. 2010. PMID: 20044062 Free PMC article. Review.
The choroid has several functions: Its vasculature is the major supply for the outer retina; impairment of the flow of oxygen from choroid to retina may cause Age-Related Macular Degeneration. ...In addition to focusing the eye, more slow …
The choroid has several functions: Its vasculature is the major supply for the outer retina; impairment of the flow of oxygen from ch …
Early Response to Anti-Vascular Endothelial Growth Factor and Two-Year Outcomes Among Eyes With Diabetic Macular Edema in Protocol T.
Bressler NM, Beaulieu WT, Maguire MG, Glassman AR, Blinder KJ, Bressler SB, Gonzalez VH, Jampol LM, Melia M, Sun JK, Wells JA 3rd; Diabetic Retinopathy Clinical Research Network. Bressler NM, et al. Am J Ophthalmol. 2018 Nov;195:93-100. doi: 10.1016/j.ajo.2018.07.030. Epub 2018 Aug 2. Am J Ophthalmol. 2018. PMID: 30077569 Free PMC article. Clinical Trial.
PURPOSE: Assess associations of 2-year visual acuity (VA) outcomes with VA and optical coherence tomography central subfield thickness (CST) after 12 weeks of anti-vascular endothelial growth factor treatment for diabetic macular edema in DRCR.net Protocol T. ...CON …
PURPOSE: Assess associations of 2-year visual acuity (VA) outcomes with VA and optical coherence tomography central subfield thicknes …
Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.
Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC; Diabetic Retinopathy Clinical Research Network. Jampol LM, et al. Ophthalmology. 2018 Jul;125(7):1054-1063. doi: 10.1016/j.ophtha.2018.01.019. Epub 2018 Mar 7. Ophthalmology. 2018. PMID: 29525602 Free PMC article. Clinical Trial.
It is unknown whether VEGF levels return to normal as the drug is cleared from the system or whether the presence of the drug affects the assay's ability to accurately measure free VEGF. ...
It is unknown whether VEGF levels return to normal as the drug is cleared from the system or whether the presence of the drug affects the as …
Soft Drusen in Age-Related Macular Degeneration: Biology and Targeting Via the Oil Spill Strategies.
Curcio CA. Curcio CA. Invest Ophthalmol Vis Sci. 2018 Mar 20;59(4):AMD160-AMD181. doi: 10.1167/iovs.18-24882. Invest Ophthalmol Vis Sci. 2018. PMID: 30357336 Free PMC article. Review.
The topographic correspondence of BLinD and SDD with cones and rods, respectively, suggest newly realized exchange pathways among outer retinal cells and across Bruch's membrane and the subretinal space, in service of highly evolved, eye-specific physiology. ...Clin …
The topographic correspondence of BLinD and SDD with cones and rods, respectively, suggest newly realized exchange pathways among outer reti …
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