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Year Number of Results
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1,034 results

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Page 1
Global epidemiology of rheumatoid arthritis.
Finckh A, Gilbert B, Hodkinson B, Bae SC, Thomas R, Deane KD, Alpizar-Rodriguez D, Lauper K. Finckh A, et al. Nat Rev Rheumatol. 2022 Oct;18(10):591-602. doi: 10.1038/s41584-022-00827-y. Epub 2022 Sep 6. Nat Rev Rheumatol. 2022. PMID: 36068354 Review.
The prevalence of RA varies globally, with generally a higher prevalence in industrialized countries, which may be explained by exposures to environmental risk factors, but also by genetic factors, differing demographics and under-reporting in other parts of the world. ...
The prevalence of RA varies globally, with generally a higher prevalence in industrialized countries, which may be explained by exposures to …
The etiology of rheumatoid arthritis.
Scherer HU, Häupl T, Burmester GR. Scherer HU, et al. J Autoimmun. 2020 Jun;110:102400. doi: 10.1016/j.jaut.2019.102400. Epub 2020 Jan 22. J Autoimmun. 2020. PMID: 31980337 Free article. Review.
Rheumatoid arthritis is a heterogeneous disease, which can be, based on data combining genetic risk factors and autoantibodies, sub-classified into ACPA-positive and -negative RA. ...ACPA are highly specific for RA, whereas RF can also be found among healthy (elderly) indi …
Rheumatoid arthritis is a heterogeneous disease, which can be, based on data combining genetic risk factors and autoantibodies, sub-c …
Rheumatoid arthritis.
Scott DL, Wolfe F, Huizinga TW. Scott DL, et al. Lancet. 2010 Sep 25;376(9746):1094-108. doi: 10.1016/S0140-6736(10)60826-4. Lancet. 2010. PMID: 20870100 Review.
Rheumatoid arthritis is characterised by persistent synovitis, systemic inflammation, and autoantibodies (particularly to rheumatoid factor and citrullinated peptide). 50% of the risk for development of rheumatoid arthritis is attributable to genetic factors. Smoking is th …
Rheumatoid arthritis is characterised by persistent synovitis, systemic inflammation, and autoantibodies (particularly to rheumatoid factor …
Epidemiology of rheumatoid arthritis: genetic and environmental influences.
Venetsanopoulou AI, Alamanos Y, Voulgari PV, Drosos AA. Venetsanopoulou AI, et al. Expert Rev Clin Immunol. 2022 Sep;18(9):923-931. doi: 10.1080/1744666X.2022.2106970. Epub 2022 Jul 29. Expert Rev Clin Immunol. 2022. PMID: 35904251 Review.
Moreover, the disease's onset is related to an interaction of genetic and environmental factors that influence its expression. AREAS COVERED: This review explores the latest knowledge on RA epidemiology and the possible risk factors associated with its presentation to iden …
Moreover, the disease's onset is related to an interaction of genetic and environmental factors that influence its expression. AREAS …
Signaling pathways in rheumatoid arthritis: implications for targeted therapy.
Ding Q, Hu W, Wang R, Yang Q, Zhu M, Li M, Cai J, Rose P, Mao J, Zhu YZ. Ding Q, et al. Signal Transduct Target Ther. 2023 Feb 17;8(1):68. doi: 10.1038/s41392-023-01331-9. Signal Transduct Target Ther. 2023. PMID: 36797236 Free PMC article. Review.
The current review intends to provide a comprehensive overview of RA, including a general introduction to the disease, historical events, epidemiology, risk factors, and pathological process, highlight the primary research progress of the disease and various signaling pathways an …
The current review intends to provide a comprehensive overview of RA, including a general introduction to the disease, historical events, ep …
Rheumatoid arthritis: advances in treatment strategies.
Prasad P, Verma S, Surbhi, Ganguly NK, Chaturvedi V, Mittal SA. Prasad P, et al. Mol Cell Biochem. 2023 Jan;478(1):69-88. doi: 10.1007/s11010-022-04492-3. Epub 2022 Jun 21. Mol Cell Biochem. 2023. PMID: 35725992 Review.
Worldwide annual incidence and prevalence rate of RA is 3 cases per 10,000 population and 1%, respectively. Several genetic and environmental (microbiota, smoking, infectious agents) factors contribute to its pathogenesis. ...However, certain adverse events associated with …
Worldwide annual incidence and prevalence rate of RA is 3 cases per 10,000 population and 1%, respectively. Several genetic and envir …
The genetics of rheumatoid arthritis.
Dedmon LE. Dedmon LE. Rheumatology (Oxford). 2020 Oct 1;59(10):2661-2670. doi: 10.1093/rheumatology/keaa232. Rheumatology (Oxford). 2020. PMID: 32638005 Review.
RA is a multigene disorder with a substantial genetic component and a heritability estimate of 60%. Large-scale Genome-Wide Association Studies (GWAS) and meta-analyses have revealed common disease-associated variants in the population that may contribute cumulatively to R …
RA is a multigene disorder with a substantial genetic component and a heritability estimate of 60%. Large-scale Genome-Wide Associati …
Genetics of rheumatoid arthritis.
Padyukov L. Padyukov L. Semin Immunopathol. 2022 Jan;44(1):47-62. doi: 10.1007/s00281-022-00912-0. Epub 2022 Jan 27. Semin Immunopathol. 2022. PMID: 35088123 Free PMC article. Review.
Both HLA and non-HLA associations suggest that the profiles of genetic associations for autoantibody-positive vs. autoantibody-negative RA are different. ...At least a part of RA risk could be explained by gene-gene and gene-environment interactions. T …
Both HLA and non-HLA associations suggest that the profiles of genetic associations for autoantibody-positive vs. autoantibody-negati …
Experimental animal models for rheumatoid arthritis.
Choudhary N, Bhatt LK, Prabhavalkar KS. Choudhary N, et al. Immunopharmacol Immunotoxicol. 2018 Jun;40(3):193-200. doi: 10.1080/08923973.2018.1434793. Epub 2018 Feb 12. Immunopharmacol Immunotoxicol. 2018. PMID: 29433367 Review.
In this review article, we focus on animal models of arthritis induced in various species along with the genetic models. The review also discussed the similarity and dissimilarities with respect to human RA....
In this review article, we focus on animal models of arthritis induced in various species along with the genetic models. The review a …
Persistent inflammatory and non-inflammatory mechanisms in refractory rheumatoid arthritis.
Buch MH, Eyre S, McGonagle D. Buch MH, et al. Nat Rev Rheumatol. 2021 Jan;17(1):17-33. doi: 10.1038/s41584-020-00541-7. Epub 2020 Dec 8. Nat Rev Rheumatol. 2021. PMID: 33293696 Review.
This Review outlines the clinical differences between PIRRA and NIRRA, the genetic and epigenetic mechanisms and immune pathways that might contribute to the immunopathogenesis of recalcitrant synovitis in PIRRA, and a possible basis for non-inflammatory symptomatology in …
This Review outlines the clinical differences between PIRRA and NIRRA, the genetic and epigenetic mechanisms and immune pathways that …
1,034 results