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177 results

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Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.
Gwyer D, Wragg NM, Wilson SL. Gwyer D, et al. Cell Tissue Res. 2019 Aug;377(2):153-159. doi: 10.1007/s00441-019-03016-8. Epub 2019 Mar 27. Cell Tissue Res. 2019. PMID: 30915550 Review.
Currently, all studies investigating BPC 157 have demonstrated consistently positive and prompt healing effects for various injury types, both traumatic and systemic and for a plethora of soft tissues. ...Promisingly, there are few studies reporting any adverse reac …
Currently, all studies investigating BPC 157 have demonstrated consistently positive and prompt healing effects for various in …
Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.
Lee E, Padgett B. Lee E, et al. Altern Ther Health Med. 2021 Jul;27(4):8-13. Altern Ther Health Med. 2021. PMID: 34324435
The other 4 patients received a combination of 2 peptide injections of BPC 157 and TB4. Of the patients who received both peptides, 75% showed significant improvement, but 25% had no relief of their knee pain. Overall, 14 of 16 patients (87.5%) had relief of their k …
The other 4 patients received a combination of 2 peptide injections of BPC 157 and TB4. Of the patients who received both pept …
BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing.
Seiwerth S, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, Drmic D, Stupnisek M, Misic M, Vuletic LB, Pavlov KH, Barisic I, Kokot A, Japjec M, Blagaic AB, Tvrdeic A, Rokotov DS, Vrcic H, Staresinic M, Sebecic B, Sikiric P. Seiwerth S, et al. Curr Pharm Des. 2018;24(18):1972-1989. doi: 10.2174/1381612824666180712110447. Curr Pharm Des. 2018. PMID: 29998800 Review.
Only BPC 157 was consistently effective in all of the models of acute/chronic injury of esophagus, stomach, duodenum and lower gastrointestinal tract, intraperitoneally, per-orally or locally. ...Thus, we claim that just BPC 157 represents in practice …
Only BPC 157 was consistently effective in all of the models of acute/chronic injury of esophagus, stomach, duodenum and lower …
The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.
Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH. Chang CH, et al. J Appl Physiol (1985). 2011 Mar;110(3):774-80. doi: 10.1152/japplphysiol.00945.2010. Epub 2010 Oct 28. J Appl Physiol (1985). 2011. PMID: 21030672 Free article.
This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 15
This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth …
Stable Gastric Pentadecapeptide BPC 157 May Recover Brain-Gut Axis and Gut-Brain Axis Function.
Sikiric P, Gojkovic S, Krezic I, Smoday IM, Kalogjera L, Zizek H, Oroz K, Vranes H, Vukovic V, Labidi M, Strbe S, Baketic Oreskovic L, Sever M, Tepes M, Knezevic M, Barisic I, Blagaic V, Vlainic J, Dobric I, Staresinic M, Skrtic A, Jurjevic I, Boban Blagaic A, Seiwerth S. Sikiric P, et al. Pharmaceuticals (Basel). 2023 Apr 30;16(5):676. doi: 10.3390/ph16050676. Pharmaceuticals (Basel). 2023. PMID: 37242459 Free PMC article. Review.
Muscle healing and function recovery appeared as the therapeutic effects of BPC 157 on the various muscle disabilities of a multitude of causes, both peripheral and central. ...Finally, encephalopathies, acting simultaneously in both the periphery and central nervou …
Muscle healing and function recovery appeared as the therapeutic effects of BPC 157 on the various muscle disabilities of a mu …
Stable Gastric Pentadecapeptide BPC 157 and Striated, Smooth, and Heart Muscle.
Staresinic M, Japjec M, Vranes H, Prtoric A, Zizek H, Krezic I, Gojkovic S, Smoday IM, Oroz K, Staresinic E, Dretar V, Yago H, Milavic M, Sikiric S, Lovric E, Batelja Vuletic L, Simeon P, Dobric I, Strbe S, Kokot A, Vlainic J, Blagaic AB, Skrtic A, Seiwerth S, Sikiric P. Staresinic M, et al. Biomedicines. 2022 Dec 12;10(12):3221. doi: 10.3390/biomedicines10123221. Biomedicines. 2022. PMID: 36551977 Free PMC article. Review.
As a follow up, we reviewed that with the BPC 157 therapy, its cytoprotective ability to organize simultaneous healing of different tissues of and full recovery of the myotendinous junction might represent the particular muscle therapy against distinctive etiopathol …
As a follow up, we reviewed that with the BPC 157 therapy, its cytoprotective ability to organize simultaneous healing of diff …
Stable Gastric Pentadecapeptide BPC 157-Possible Novel Therapy of Glaucoma and Other Ocular Conditions.
Sikiric P, Kokot A, Kralj T, Zlatar M, Masnec S, Lazic R, Loncaric K, Oroz K, Sablic M, Boljesic M, Antunovic M, Sikiric S, Strbe S, Stambolija V, Beketic Oreskovic L, Kavelj I, Novosel L, Zubcic S, Krezic I, Skrtic A, Jurjevic I, Boban Blagaic A, Seiwerth S, Staresinic M. Sikiric P, et al. Pharmaceuticals (Basel). 2023 Jul 24;16(7):1052. doi: 10.3390/ph16071052. Pharmaceuticals (Basel). 2023. PMID: 37513963 Free PMC article. Review.
Thereby, we revealed BPC 157 cytoprotective therapy with strong vascular rescuing capabilities in glaucoma therapy. ...Thus, we further advocate BPC 157 as a therapeutic agent in ocular disease....
Thereby, we revealed BPC 157 cytoprotective therapy with strong vascular rescuing capabilities in glaucoma therapy. ...Thus, w …
Pentadecapeptide BPC 157 and the central nervous system.
Vukojevic J, Milavić M, Perović D, Ilić S, Čilić AZ, Đuran N, Štrbe S, Zoričić Z, Filipčić I, Brečić P, Seiverth S, Sikirić P. Vukojevic J, et al. Neural Regen Res. 2022 Mar;17(3):482-487. doi: 10.4103/1673-5374.320969. Neural Regen Res. 2022. PMID: 34380875 Free PMC article. Review.
Firstly, given in the reperfusion, BPC 157 counteracted bilateral clamping of the common carotid arteries-induced stroke, sustained brain neuronal damages were resolved in rats as well as disturbed memory, locomotion, and coordination. ...Thus, these disturbances ma …
Firstly, given in the reperfusion, BPC 157 counteracted bilateral clamping of the common carotid arteries-induced stroke, sust …
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.
Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB, Sikiric P. Seiwerth S, et al. Front Pharmacol. 2021 Jun 29;12:627533. doi: 10.3389/fphar.2021.627533. eCollection 2021. Front Pharmacol. 2021. PMID: 34267654 Free PMC article. Review.
Likewise, BPC 157 may prevent and/or attenuate or eliminate, thus, counteract both arterial and venous thrombosis. Then, confronted with obstructed vessels, there is circumvention of the occlusion, which may be the particular action of BPC 157 in ische …
Likewise, BPC 157 may prevent and/or attenuate or eliminate, thus, counteract both arterial and venous thrombosis. Then, confr …
Fistulas Healing. Stable Gastric Pentadecapeptide BPC 157 Therapy.
Sikiric P, Drmic D, Sever M, Klicek R, Blagaic AB, Tvrdeic A, Kralj T, Kovac KK, Vukojevic J, Siroglavic M, Gojkovic S, Krezic I, Pavlov KH, Rasic D, Mirkovic I, Kokot A, Skrtic A, Seiwerth S. Sikiric P, et al. Curr Pharm Des. 2020;26(25):2991-3000. doi: 10.2174/1381612826666200424180139. Curr Pharm Des. 2020. PMID: 32329684 Review.
This review is focused on the healing of fistulas and stable gastric pentadecapeptide BPC 157. Assuming that the healing of the various wounds is essential also for the gastrointestinal fistulas healing, the healing effect on fistulas in rats, consistently noted wit …
This review is focused on the healing of fistulas and stable gastric pentadecapeptide BPC 157. Assuming that the healing of th …
177 results