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Year Number of Results
2016 5
2017 83
2018 178
2019 169
2020 76
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Light therapy for preventing seasonal affective disorder.
Nussbaumer-Streit B, Forneris CA, Morgan LC, Van Noord MG, Gaynes BN, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Gartlehner G. Nussbaumer-Streit B, et al. Cochrane Database Syst Rev. 2019 Mar 18;3(3):CD011269. doi: 10.1002/14651858.CD011269.pub3. Cochrane Database Syst Rev. 2019. PMID: 30883670 Free PMC article.
BACKGROUND: Seasonal affective disorder (SAD) is a seasonal pattern of recurrent major depressive episodes that most commonly occurs during autumn or winter and remits in spring. ...The predictable seasonal aspect of SAD provides a promising opportunit …
BACKGROUND: Seasonal affective disorder (SAD) is a seasonal pattern of recurrent major depressive episodes that …
Harm reduction-a systematic review on effects of alcohol reduction on physical and mental symptoms.
Charlet K, Heinz A. Charlet K, et al. Addict Biol. 2017 Sep;22(5):1119-1159. doi: 10.1111/adb.12414. Epub 2016 Jun 29. Addict Biol. 2017. PMID: 27353220 Review.
Furthermore, reduced withdrawal symptoms, prevalence of psychiatric episodes and duration of in-patient hospital days, improvement of anxiety and depression symptoms, self-confidence, physical and mental quality of life, fewer alcohol-related ad …
Furthermore, reduced withdrawal symptoms, prevalence of psychiatric episodes and duration of in-patient hospital days, …
Depression and obstructive sleep apnea.
Hobzova M, Prasko J, Vanek J, Ociskova M, Genzor S, Holubova M, Grambal A, Latalova K. Hobzova M, et al. Neuro Endocrinol Lett. 2017 Oct;38(5):343-352. Neuro Endocrinol Lett. 2017. PMID: 29106789 Review.
Patients with the comorbid major depression and OSA reported more severe and longer episodes of depression. Nevertheless, the information on the effect of the treatment of OSA using CPAP on the depressive symptoms was limited. ...C …
Patients with the comorbid major depression and OSA reported more severe and longer episodes of depression. Neve …
Attentional control, rumination and recurrence of depression.
Figueroa CA, DeJong H, Mocking RJT, Fox E, Rive MM, Schene AH, Stein A, Ruhé HG. Figueroa CA, et al. J Affect Disord. 2019 Sep 1;256:364-372. doi: 10.1016/j.jad.2019.05.072. Epub 2019 May 30. J Affect Disord. 2019. PMID: 31207560
BACKGROUND: Depressive recurrence is highly prevalent and adds significantly to the burden of depressive disorder. Whilst some clinical predictors of recurrence have been clearly demonstrated (e.g. residual symptoms, previous episodes), the cogn …
BACKGROUND: Depressive recurrence is highly prevalent and adds significantly to the burden of depressive disorder. Whil …
Lacosamide in bipolar disorder: A 30-day comparison to a retrospective control group treated with other antiepileptics.
Cuomo I, Piacentino D, Kotzalidis GD, Lionetto L, De Filippis S. Cuomo I, et al. Psychiatry Clin Neurosci. 2018 Dec;72(12):864-875. doi: 10.1111/pcn.12784. Epub 2018 Oct 19. Psychiatry Clin Neurosci. 2018. PMID: 30251375 Free article.
Age, substance use disorder comorbidity, episode type, and educational level significantly affected results. No interactions were found amongst these parameters. CONCLUSION: Lacosamide was effective in reducing psychopathology, mania, depression, and a …
Age, substance use disorder comorbidity, episode type, and educational level significantly affected results. No interactions w …
Association of translocator protein total distribution volume with duration of untreated major depressive disorder: a cross-sectional study.
Setiawan E, Attwells S, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Xu C, Sharma S, Kish S, Houle S, Meyer JH. Setiawan E, et al. Lancet Psychiatry. 2018 Apr;5(4):339-347. doi: 10.1016/S2215-0366(18)30048-8. Epub 2018 Feb 26. Lancet Psychiatry. 2018. PMID: 29496589
To be enrolled, participants with major depressive episodes had to score a minimum of 17 on the 17-item Hamilton Depression Rating Scale, and had to be medication free or taking a stable dose of medication for at least 4 weeks before PET scannin …
To be enrolled, participants with major depressive episodes had to score a minimum of 17 on the 17-item Hamilton Dep
A pilot study of brexpiprazole for bipolar depression.
Brown ES, Khaleghi N, Van Enkevort E, Ivleva E, Nakamura A, Holmes T, Mason BL, Escalante C. Brown ES, et al. J Affect Disord. 2019 Apr 15;249:315-318. doi: 10.1016/j.jad.2019.02.056. Epub 2019 Feb 19. J Affect Disord. 2019. PMID: 30802696
BACKGROUND: Past studies suggest that brexpiprazole is an effective adjunctive treatment for major depressive disorder and schizophrenia; however, no studies have examined brexpiprazole for bipolar depression. ...CONCLUSION: To our knowledge, th …
BACKGROUND: Past studies suggest that brexpiprazole is an effective adjunctive treatment for major depressive disord
Genes, biomarkers, and clinical features associated with the course of bipolar disorder.
Smedler E, Bergen SE, Song J, Landén M. Smedler E, et al. Eur Neuropsychopharmacol. 2019 Oct;29(10):1152-1160. doi: 10.1016/j.euroneuro.2019.07.132. Epub 2019 Aug 1. Eur Neuropsychopharmacol. 2019. PMID: 31378653 Free article.
There is considerable variability in the severity of bipolar disorder, e.g., in terms of the frequency of inpatient episodes. ...Compared with those with a stable or recuperant trajectory, these patients featured lower functioning, more antidepressant treatment
There is considerable variability in the severity of bipolar disorder, e.g., in terms of the frequency of inpatient episodes. …
Mixed states in bipolar disorder - changes in DSM-5 and current treatment recommendations.
Betzler F, Stöver LA, Sterzer P, Köhler S. Betzler F, et al. Int J Psychiatry Clin Pract. 2017 Nov;21(4):244-258. doi: 10.1080/13651501.2017.1311921. Epub 2017 Apr 18. Int J Psychiatry Clin Pract. 2017. PMID: 28417647 Review.
CONCLUSIONS: Mixed states are of a high clinical relevance and the DSM-5 criteria substantially reduced the diagnostic threshold. Besides advantages of a better characterization of patients with former DSM-IV-defined mixed episodes, disadvantages arise for example d …
CONCLUSIONS: Mixed states are of a high clinical relevance and the DSM-5 criteria substantially reduced the diagnostic threshold. Bes …
GERI-BD: A Randomized Double-Blind Controlled Trial of Lithium and Divalproex in the Treatment of Mania in Older Patients With Bipolar Disorder.
Young RC, Mulsant BH, Sajatovic M, Gildengers AG, Gyulai L, Al Jurdi RK, Beyer J, Evans J, Banerjee S, Greenberg R, Marino P, Kunik ME, Chen P, Barrett M, Schulberg HC, Bruce ML, Reynolds CF 3rd, Alexopoulos GS; GERI-BD Study Group. Young RC, et al. Am J Psychiatry. 2017 Nov 1;174(11):1086-1093. doi: 10.1176/appi.ajp.2017.15050657. Epub 2017 Aug 4. Am J Psychiatry. 2017. PMID: 29088928 Free PMC article. Clinical Trial.
METHOD: The authors compared the tolerability and efficacy of lithium carbonate and divalproex in 224 inpatients and outpatients age 60 or older with bipolar I disorder who presented with a manic, hypomanic, or mixed episode. ...CONCLUSIONS: Both lithium and divalpr …
METHOD: The authors compared the tolerability and efficacy of lithium carbonate and divalproex in 224 inpatients and outpatients age 60 or o …
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