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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 2
1988 7
1989 5
1990 2
1991 3
1992 4
1993 1
1994 5
1995 5
1996 5
1997 9
1998 11
1999 14
2000 12
2001 21
2002 16
2003 14
2004 21
2005 14
2006 20
2007 24
2008 24
2009 35
2010 28
2011 26
2012 29
2013 32
2014 32
2015 58
2016 62
2017 76
2018 74
2019 65
2020 74
2021 78
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820 results
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Page 1
ACG Clinical Guideline: Management of Crohn's Disease in Adults.
Lichtenstein GR, Loftus EV, Isaacs KL, Regueiro MD, Gerson LB, Sands BE. Lichtenstein GR, et al. Am J Gastroenterol. 2018 Apr;113(4):481-517. doi: 10.1038/ajg.2018.27. Epub 2018 Mar 27. Am J Gastroenterol. 2018. PMID: 29610508
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic, immunologic, and environmental influences. The incidence of Crohn's disease has steadily increased over the past several decades. ...
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic, immunologic, and environmental
The treatment-naive microbiome in new-onset Crohn's disease.
Gevers D, Kugathasan S, Denson LA, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan XC, Kostic AD, Luo C, González A, McDonald D, Haberman Y, Walters T, Baker S, Rosh J, Stephens M, Heyman M, Markowitz J, Baldassano R, Griffiths A, Sylvester F, Mack D, Kim S, Crandall W, Hyams J, Huttenhower C, Knight R, Xavier RJ. Gevers D, et al. Cell Host Microbe. 2014 Mar 12;15(3):382-392. doi: 10.1016/j.chom.2014.02.005. Cell Host Microbe. 2014. PMID: 24629344 Free PMC article.
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implicate an underlying role for aberrant immune responses to intestinal microbiota. ...Comparing the microbial signatures between the ileum, the …
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implic …
Crohn's Disease: Genetics Update.
Wang MH, Picco MF. Wang MH, et al. Gastroenterol Clin North Am. 2017 Sep;46(3):449-461. doi: 10.1016/j.gtc.2017.05.002. Epub 2017 Jul 19. Gastroenterol Clin North Am. 2017. PMID: 28838408 Review.
Since the discovery of the first Crohn's disease (CD) gene NOD2 in 2001, 140 genetic loci have been found in whites using high-throughput genome-wide association studies. ...Algorithms that incorporate specific genetic risk alleles with other biomarkers will …
Since the discovery of the first Crohn's disease (CD) gene NOD2 in 2001, 140 genetic loci have been found in whites usi …
JAK-STAT pathway targeting for the treatment of inflammatory bowel disease.
Salas A, Hernandez-Rocha C, Duijvestein M, Faubion W, McGovern D, Vermeire S, Vetrano S, Vande Casteele N. Salas A, et al. Nat Rev Gastroenterol Hepatol. 2020 Jun;17(6):323-337. doi: 10.1038/s41575-020-0273-0. Epub 2020 Mar 19. Nat Rev Gastroenterol Hepatol. 2020. PMID: 32203403 Review.
Cytokines are involved in intestinal homeostasis and pathological processes associated with inflammatory bowel disease (IBD). The biological effects of cytokines, including several involved in the pathology of Crohn's disease and ulcerative colitis, oc …
Cytokines are involved in intestinal homeostasis and pathological processes associated with inflammatory bowel disease (IBD). The bio …
The Microbiome in Crohn's Disease: Role in Pathogenesis and Role of Microbiome Replacement Therapies.
Khanna S, Raffals LE. Khanna S, et al. Gastroenterol Clin North Am. 2017 Sep;46(3):481-492. doi: 10.1016/j.gtc.2017.05.004. Epub 2017 Jul 19. Gastroenterol Clin North Am. 2017. PMID: 28838410 Review.
Individuals with a genetic predisposition to Crohn's disease develop aberrant immune responses to environmental triggers. The gastrointestinal microbiota is increasingly recognized to play an important role in the development of Crohn's disea
Individuals with a genetic predisposition to Crohn's disease develop aberrant immune responses to environmental trigger …
Bile Acid diarrhea: prevalence, pathogenesis, and therapy.
Camilleri M. Camilleri M. Gut Liver. 2015 May 23;9(3):332-9. doi: 10.5009/gnl14397. Gut Liver. 2015. PMID: 25918262 Free PMC article. Review.
Bile acid diarrhea (BAD) is usually seen in patients with ileal Crohn's disease or ileal resection. However, 25% to 50% of patients with functional diarrhea or diarrhea-predominant irritable bowel syndrome (IBS-D) also have evidence of BAD. ...
Bile acid diarrhea (BAD) is usually seen in patients with ileal Crohn's disease or ileal resection. However, 25% to 50% …
Epidemiology, Natural History, and Risk Stratification of Crohn's Disease.
Aniwan S, Park SH, Loftus EV Jr. Aniwan S, et al. Gastroenterol Clin North Am. 2017 Sep;46(3):463-480. doi: 10.1016/j.gtc.2017.05.003. Epub 2017 Jul 19. Gastroenterol Clin North Am. 2017. PMID: 28838409 Review.
Crohn's disease (CD) is a chronic condition that can result in significant morbidity and disability. ...In this review, updated data regarding the incidence and prevalence of CD, important environmental risk factors, natural history of the disease, and
Crohn's disease (CD) is a chronic condition that can result in significant morbidity and disability. ...In this review,
Modern management of perianal fistulas in Crohn's disease: future directions.
Kotze PG, Shen B, Lightner A, Yamamoto T, Spinelli A, Ghosh S, Panaccione R. Kotze PG, et al. Gut. 2018 Jun;67(6):1181-1194. doi: 10.1136/gutjnl-2017-314918. Epub 2018 Jan 13. Gut. 2018. PMID: 29331943 Review.
Perianal fistulae in patients with Crohn's disease (CD) can be associated with significant morbidity resulting in negative impact on quality of life. ...
Perianal fistulae in patients with Crohn's disease (CD) can be associated with significant morbidity resulting in negat …
Long-term Efficacy of Vedolizumab for Crohn's Disease.
Vermeire S, Loftus EV Jr, Colombel JF, Feagan BG, Sandborn WJ, Sands BE, Danese S, D'Haens GR, Kaser A, Panaccione R, Rubin DT, Shafran I, McAuliffe M, Kaviya A, Sankoh S, Mody R, Abhyankar B, Smyth M. Vermeire S, et al. J Crohns Colitis. 2017 Apr 1;11(4):412-424. doi: 10.1093/ecco-jcc/jjw176. J Crohns Colitis. 2017. PMID: 27683798 Clinical Trial.
BACKGROUND AND AIMS: Vedolizumab is a gut-selective alpha4beta7 integrin antagonist therapy for ulcerative colitis and Crohn's disease. The GEMINI long-term safety [LTS] trial is an ongoing open-label study investigating the safety of vedolizumab. We present …
BACKGROUND AND AIMS: Vedolizumab is a gut-selective alpha4beta7 integrin antagonist therapy for ulcerative colitis and Crohn's
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