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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 16
2008 19
2009 20
2010 20
2011 29
2012 24
2013 26
2014 15
2015 33
2016 25
2017 24
2018 29
2019 22
2020 31
2021 19
2022 19
2023 10
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2026 5

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376 results

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Page 1
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.
Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babić D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenović AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goleva SB, Gordon SD, Goçi A, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SMJ, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljević M, Javanbakht A, Jenkins GD, Johnson J, Jones I, Jovanovic T, … See abstract for full author list ➔ Nievergelt CM, et al. Nat Genet. 2024 May;56(5):792-808. doi: 10.1038/s41588-024-01707-9. Epub 2024 Apr 18. Nat Genet. 2024. PMID: 38637617 Free PMC article.
Convergent multi-omic approaches identified 43 potential causal genes, broadly classified as neurotransmitter and ion channel synaptic modulators (for example, GRIA1, GRM8 and CACNA1E), developmental, axon guidance and transcription factors (for example, FOXP2, EFNA5 and DCC …
Convergent multi-omic approaches identified 43 potential causal genes, broadly classified as neurotransmitter and ion channel synaptic modul …
Decoding transcriptional identity in developing human sensory neurons and organoid modeling.
Lu T, Wang M, Zhou W, Ni Q, Yue Y, Wang W, Shi Y, Liu Z, Li C, Hong B, Zhou X, Zhong S, Wang K, Zeng B, Zhang J, Wang W, Zhang X, Wu Q, Wang X. Lu T, et al. Cell. 2024 Dec 26;187(26):7374-7393.e28. doi: 10.1016/j.cell.2024.10.023. Epub 2024 Nov 12. Cell. 2024. PMID: 39536745 Free article.
Additionally, we identify a human-enriched NTRK3(+)/DCC(+) nociceptor subtype, which is involved in multimodal nociceptive processing. Mimicking the programmed activation of signaling pathways in vivo, we successfully establish functional human DRG organoids and underscore …
Additionally, we identify a human-enriched NTRK3(+)/DCC(+) nociceptor subtype, which is involved in multimodal nociceptive processing …
Prenatal Diagnosed Agenesis of the Corpus Callosum: Identifying the Underlying Genetic Etiologies.
Wei X, Cai L, Zhang L, Chen J, Zhang Y, Meng M, Yang Y, Zhou X, Zou G, Sun L. Wei X, et al. Prenat Diagn. 2024 Sep;44(10):1142-1149. doi: 10.1002/pd.6641. Epub 2024 Aug 8. Prenat Diagn. 2024. PMID: 39117575
ES was performed in 26 cases with normal CMA, revealing pathogenic or likely pathogenic gene variations in 12 cases (46.2%, 12/26), involving L1CMA, SMARCB1, PPP2R1A, ARID1B, USP34, CDC42, NFIA and DCC genes. The detection rates of ES in isolated and non-isolated ACC were …
ES was performed in 26 cases with normal CMA, revealing pathogenic or likely pathogenic gene variations in 12 cases (46.2%, 12/26), involvin …
Investigating the shared genetic architecture between obesity and depression: a large-scale genomewide cross-trait analysis.
Yuan L, Su Y, Zhao J, Cho M, Wang D, Yuan L, Li M, Zheng D, Piao H, Wang Y, Zhu Z, Li D, Wang T, Ha KT, Park W, Liu K. Yuan L, et al. Front Endocrinol (Lausanne). 2025 May 8;16:1578944. doi: 10.3389/fendo.2025.1578944. eCollection 2025. Front Endocrinol (Lausanne). 2025. PMID: 40405979 Free PMC article.
RESULTS: Our analysis revealed genetic correlations and bidirectional positive causal relationships between obesity and depression, highlighting shared risk SNP (rs10789340). We identified RPL31P12, NEGR1, and DCC as common risk genes for obesity and depression. Using the …
RESULTS: Our analysis revealed genetic correlations and bidirectional positive causal relationships between obesity and depression, highligh …
Large Bowel Genetic Background and Inflammatory Processes in Carcinogenesis--Systematic Review.
Szylberg Ł, Janiczek M, Popiel A, Marszałek A. Szylberg Ł, et al. Adv Clin Exp Med. 2015 Jul-Aug;24(4):555-63. doi: 10.17219/acem/31239. Adv Clin Exp Med. 2015. PMID: 26469098 Free article.
Well-known genetic bases for the carcinogenesis of CRC include chromosomal changes characteristic of the chromosomal instability pathway which correlates with specific and well-defined genetic alterations (such as APC, K-RAS, DCC and p53) and genomic instability characteri …
Well-known genetic bases for the carcinogenesis of CRC include chromosomal changes characteristic of the chromosomal instability pathway whi …
Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
Kimbrel NA, Ashley-Koch AE, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Trafton JA, Coon H, Docherty AR, Mullins N, Ruderfer DM, Harvey PD, McMahon BH, Oslin DW, Beckham JC, Hauser ER, Hauser MA; Million Veteran Program Suicide Exemplar Workgroup, the International Suicide Genetics Consortium, the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, and the Veterans Affairs Million Veteran Program. Kimbrel NA, et al. JAMA Psychiatry. 2023 Feb 1;80(2):135-145. doi: 10.1001/jamapsychiatry.2022.3896. JAMA Psychiatry. 2023. PMID: 36515925 Free PMC article.
Top single-nucleotide variants were largely intronic in nature; 5 were independently replicated in ISGC, including rs6557168 in ESR1, rs12808482 in DRD2, rs77641763 in EXD3, rs10671545 in DCC, and rs36006172 in TRAF3. Associations for FBXL19 and AC018880.2 were not replica …
Top single-nucleotide variants were largely intronic in nature; 5 were independently replicated in ISGC, including rs6557168 in ESR1, rs1280 …
Multitrait GWAS of non-suicidal self-injury and the polygenetic effects on child psychopathology and brain structures.
Sun Y, Zhao G, Zhang Y, Lu Z, Kang Z, Sun J, Feng X, Guo J, Liao Y, Guo L, Yang Y, Zhang D, Bi W, Chen R, Yue W. Sun Y, et al. Cell Rep Med. 2025 May 20;6(5):102119. doi: 10.1016/j.xcrm.2025.102119. Epub 2025 May 9. Cell Rep Med. 2025. PMID: 40347941 Free PMC article.
Three risk loci are associated with NSSI at 7q31.2 (rs62474683), DCC (rs4372758), and LCA5L/GET1/GET1-SH3BGR (rs2837022). Increased expression levels of GET1/SH3BGR in hippocampus relates to NSSI risk. ...
Three risk loci are associated with NSSI at 7q31.2 (rs62474683), DCC (rs4372758), and LCA5L/GET1/GET1-SH3BGR (rs2837022). Increased e …
Genetic Susceptibility of DCC Gene in Gallbladder Cancer in Kashmir and Meta-Analysis.
Malik MA, Malik SA, Haq MG, Bangri SA, Ahmad SZ, Shah OJ, Shah ZA. Malik MA, et al. Nutr Cancer. 2022;74(3):947-955. doi: 10.1080/01635581.2021.1949728. Epub 2021 Jul 14. Nutr Cancer. 2022. PMID: 34259111
Deleted in colorectal carcinoma (DCC) A > G (rs714) is the most widely studied SNP of tumor suppressor DCC gene found to be associated with increased risk of various cancers. ...Meta-analysis results showed that DCC A > G (rs714) is associated with incr …
Deleted in colorectal carcinoma (DCC) A > G (rs714) is the most widely studied SNP of tumor suppressor DCC gene found to be …
Distal cholangiocarcinoma.
Dickson PV, Behrman SW. Dickson PV, et al. Surg Clin North Am. 2014 Apr;94(2):325-42. doi: 10.1016/j.suc.2013.12.004. Surg Clin North Am. 2014. PMID: 24679424 Review.
The prognosis and cure rate of DCC is improved over that of PDA, but it remains a highly lethal disease. Although the diagnostic and therapeutic management of DCC is not dissimilar from PDA, the pathophysiology is, in many instances, distinctly different. A multi-di …
The prognosis and cure rate of DCC is improved over that of PDA, but it remains a highly lethal disease. Although the diagnostic and …
376 results