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PDA-TOLERATE Trial: An Exploratory Randomized Controlled Trial of Treatment of Moderate-to-Large Patent Ductus Arteriosus at 1 Week of Age.
Clyman RI, Liebowitz M, Kaempf J, Erdeve O, Bulbul A, Håkansson S, Lindqvist J, Farooqi A, Katheria A, Sauberan J, Singh J, Nelson K, Wickremasinghe A, Dong L, Hassinger DC, Aucott SW, Hayashi M, Heuchan AM, Carey WA, Derrick M, Fernandez E, Sankar M, Leone T, Perez J, Serize A; PDA-TOLERATE (PDA: TO LEave it alone or Respond And Treat Early) Trial Investigators. Clyman RI, et al. J Pediatr. 2019 Feb;205:41-48.e6. doi: 10.1016/j.jpeds.2018.09.012. Epub 2018 Oct 16. J Pediatr. 2019. PMID: 30340932 Free PMC article. Clinical Trial.
OBJECTIVE: To compare early routine pharmacologic treatment of moderate-to-large patent ductus arteriosus (PDA) at the end of week 1 with a conservative approach that requires prespecified respiratory and hemodynamic criteria before treatment can be given. .. …
OBJECTIVE: To compare early routine pharmacologic treatment of moderate-to-large patent ductus arteriosus (PDA) at the …
The American Association for Thoracic Surgery (AATS) 2024 expert consensus document: Management of neonates and infants with Ebstein anomaly.
Konstantinov IE, Chai P, Bacha E, Caldarone CA, Da Silva JP, Da Fonseca Da Silva L, Dearani J, Hornberger L, Knott-Craig C, Del Nido P, Qureshi M, Sarris G, Starnes V, Tsang V. Konstantinov IE, et al. J Thorac Cardiovasc Surg. 2024 Aug;168(2):311-324. doi: 10.1016/j.jtcvs.2024.04.018. Epub 2024 Apr 27. J Thorac Cardiovasc Surg. 2024. PMID: 38685467
Neonates without high-risk features of EA may be monitored for spontaneous closure of the patent ductus arteriosus (PDA). Hemodynamically stable neonates with significant pulmonary regurgitation at risk for circular shunt with normal right ventricular systoli …
Neonates without high-risk features of EA may be monitored for spontaneous closure of the patent ductus arteriosus (PDA …
Left-to-right shunt lesions.
Driscoll DJ. Driscoll DJ. Pediatr Clin North Am. 1999 Apr;46(2):355-68, x. doi: 10.1016/s0031-3955(05)70123-1. Pediatr Clin North Am. 1999. PMID: 10218080 Review.
This article discusses: the incidence, types, embryology, clinical presentations, physical examinations, electrocardiographic features, chest radiographs, echocardiographic and cardiac catheterization issues, treatment, natural history of atrial septal defects, and outcomes of tr …
This article discusses: the incidence, types, embryology, clinical presentations, physical examinations, electrocardiographic features, ches …
Definitive Closure of the Patent Ductus Arteriosus in Preterm Infants and Subsequent Short-Term Respiratory Outcomes.
Wheeler CR, Vogel ER, Cusano MA, Friedman KG, Callahan R, Porras D, Ibla JC, Levy PT. Wheeler CR, et al. Respir Care. 2022 May;67(5):594-606. doi: 10.4187/respcare.09489. Respir Care. 2022. PMID: 35473850 Review.
A persistent patent ductus arteriosus (PDA) can have significant clinical consequences in preterm infants, depending on the degree of left-to-right shunting, its impact on cardiac performance, and associated perinatal risk factors that can mitigate or exacerb …
A persistent patent ductus arteriosus (PDA) can have significant clinical consequences in preterm infants, depending on …
Efficacy of pharmacologic closure of patent ductus arteriosus in small-for-gestational-age extremely preterm infants.
Boghossian NS, Do BT, Bell EF, Dagle JM, Brumbaugh JE, Stoll BJ, Vohr BR, Das A, Shankaran S, Sanchez PJ, Wyckoff MH, Bethany Ball M; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Boghossian NS, et al. Early Hum Dev. 2017 Oct;113:10-17. doi: 10.1016/j.earlhumdev.2017.07.011. Epub 2017 Jul 8. Early Hum Dev. 2017. PMID: 28697406 Free PMC article. Clinical Trial.
BACKGROUND: Optimal management of the patent ductus arteriosus (PDA) in preterm infants remains controversial. Therefore, studies identifying infants who are most likely to benefit from PDA treatment are needed. ...
BACKGROUND: Optimal management of the patent ductus arteriosus (PDA) in preterm infants remains controversial. Therefor …
Variation and comparative effectiveness of patent ductus arteriosus pharmacotherapy in extremely low birth weight infants.
ElHassan NO, Bird TM, King AJ, Ambadwar PB, Jaquiss RD, Kaiser JR, Robbins JM. ElHassan NO, et al. J Neonatal Perinatal Med. 2014 Jan 1;7(3):229-35. doi: 10.3233/NPM-14814015. J Neonatal Perinatal Med. 2014. PMID: 25322995
BACKGROUND: Patent ductus arteriosus (PDA) occurs in 70% of extremely low birth weight (ELBW, birth weight <1000 g) infants. Approximately 34% of ELBW infants with a PDA have spontaneous closure. Failure of the ductus arteriosus to close has …
BACKGROUND: Patent ductus arteriosus (PDA) occurs in 70% of extremely low birth weight (ELBW, birth weight <1000 g) …
Prolonged Tracheal Intubation and the Association Between Patent Ductus Arteriosus and Bronchopulmonary Dysplasia: A Secondary Analysis of the PDA-TOLERATE trial.
Clyman RI, Kaempf J, Liebowitz M, Erdeve O, Bulbul A, Håkansson S, Lindqvist J, Farooqi A, Katheria A, Sauberan J, Singh J, Nelson K, Wickremasinghe A, Dong L, Hassinger DC, Aucott SW, Hayashi M, Heuchan AM, Carey WA, Derrick M, Fernandez E, Sankar M, Leone T, Perez J, Serize A; PDA-TOLERATE Trial Investigators. Clyman RI, et al. J Pediatr. 2021 Feb;229:283-288.e2. doi: 10.1016/j.jpeds.2020.09.047. Epub 2020 Oct 28. J Pediatr. 2021. PMID: 32979387 Free PMC article. Clinical Trial.
In the PDA-TOLERATE trial, persistent (even for several weeks) moderate to large patent ductus arteriosus (PDA) was not associated with an increased risk of BPD when the infant required <10 days of intubation. ...
In the PDA-TOLERATE trial, persistent (even for several weeks) moderate to large patent ductus arteriosus (PDA) was not …
Clinical outcomes and costs of transcatheter as compared with surgical closure of patent ductus arteriosus. The Patient Ductus Arteriosus Closure Comparative Study Group.
Gray DT, Fyler DC, Walker AM, Weinstein MC, Chalmers TC. Gray DT, et al. N Engl J Med. 1993 Nov 18;329(21):1517-23. doi: 10.1056/NEJM199311183292101. N Engl J Med. 1993. PMID: 7695658 Free article.
BACKGROUND: Transcatheter implantation of the Rashkind PDA occluder is an alternative to conventional surgical closure of isolated patent ductus arteriosus. Neither the clinical outcomes nor the costs of these procedures have been formally compared. ...The pa …
BACKGROUND: Transcatheter implantation of the Rashkind PDA occluder is an alternative to conventional surgical closure of isolated patent
Superior mesenteric artery blood flow velocities following medical treatment of a patent ductus arteriosus.
Yanowitz TD, Reese J, Gillam-Krakauer M, Cochran CM, Jegatheesan P, Lau J, Tran VT, Walsh M, Carey WA, Fujii A, Fabio A, Clyman R. Yanowitz TD, et al. J Pediatr. 2014 Mar;164(3):661-3. doi: 10.1016/j.jpeds.2013.11.002. Epub 2013 Dec 8. J Pediatr. 2014. PMID: 24321538 Free PMC article. Clinical Trial.
We examined superior mesenteric artery blood flow velocity in response to feeding in infants randomized to trophic feeds (n = 16) or nil per os (n = 18) during previous treatment for patent ductus arteriosus. Blood flow velocity increased earlier in the fed i …
We examined superior mesenteric artery blood flow velocity in response to feeding in infants randomized to trophic feeds (n = 16) or nil per …
45 results