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29 results

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Page 1
Weight of evidence analysis of the tumorigenic potential of 1,3-dichloropropene supports a threshold-based risk assessment.
Yan ZJ, Bartels M, Gollapudi B, Driver J, Himmelstein M, Gehen S, Juberg D, van Wesenbeeck I, Terry C, Rasoulpour R. Yan ZJ, et al. Crit Rev Toxicol. 2020 Nov;50(10):836-860. doi: 10.1080/10408444.2020.1845119. Epub 2021 Feb 2. Crit Rev Toxicol. 2020. PMID: 33528302 Free article. Review.
The CARC recommends using a non-linear approach (i.e. reference dose (RfD)) that will adequately account for all chronic toxicity including carcinogenicity, that could result from exposure to 1,3-dichloropropene."...
The CARC recommends using a non-linear approach (i.e. reference dose (RfD)) that will adequately account for all chronic toxicity inc …
An Ecologic Study of the Association between 1,3-Dichloropropene and Pancreatic Cancer.
McGwin G Jr, Griffin RL. McGwin G Jr, et al. Cancers (Basel). 2022 Dec 27;15(1):150. doi: 10.3390/cancers15010150. Cancers (Basel). 2022. PMID: 36612145 Free PMC article.
A negative binomial regression adjusted for selected lifestyle risk factors of pancreatic cancer (i.e., obesity, alcohol use, and smoking prevalence) estimated rate ratios (RRs) and associated 95% confidence intervals (CIs)for the association between 1,3-D quartiles and pa …
A negative binomial regression adjusted for selected lifestyle risk factors of pancreatic cancer (i.e., obesity, alcohol use, and smo …
Atmospheric volatilization and distribution of (Z)- and (E)-1,3-dichloropropene in field beds with and without plastic covers.
Thomas JE, Allen LH Jr, McCormack LA, Vu JC, Dickson DW, Ou LT. Thomas JE, et al. J Environ Sci Health B. 2004;39(5-6):709-23. J Environ Sci Health B. 2004. PMID: 15620080
After injection of the commercial fumigant Telone II by conventional chisels to field beds at 30cm depth which were covered with polyethylene film (PE), virtually impermeable film, or no cover (bare), (Z)- and (E)-1,3-D rapidly diffused upward. Twenty hours after injection …
After injection of the commercial fumigant Telone II by conventional chisels to field beds at 30cm depth which were covered with polyethylen …
1,3-Dichloropropene epoxides: intermediates in bioactivation of the promutagen 1,3-dichloropropene.
Schneider M, Quistad GB, Casida JE. Schneider M, et al. Chem Res Toxicol. 1998 Oct;11(10):1137-44. doi: 10.1021/tx980126y. Chem Res Toxicol. 1998. PMID: 9778309
The mutagenicity of the epoxides is due either to their direct action or to a degradation product formed at physiological pH, i.e., 3-chloro-2-hydroxypropanal or its dehydrochlorination products. The candidate mutagens methylglyoxal and glycidaldehyde are not detected as b …
The mutagenicity of the epoxides is due either to their direct action or to a degradation product formed at physiological pH, i.e., 3 …
Mechanism of 1,3-dichloropropene-induced rat liver carcinogenesis.
Klaunig JE, Gehen SC, Wang Z, Klein PJ, Billington R. Klaunig JE, et al. Toxicol Sci. 2015 Jan;143(1):6-15. doi: 10.1093/toxsci/kfu221. Epub 2014 Oct 28. Toxicol Sci. 2015. PMID: 25354764
Following treatment, placental form glutathione S-transferase (GSTP) positive and GSTP-negative liver focal lesions were quantitated as to size and number. 1,3-D treatment had no effect on GSTP-positive foci number or relative size but significantly increased the number, labeling …
Following treatment, placental form glutathione S-transferase (GSTP) positive and GSTP-negative liver focal lesions were quantitated as to s …
Mitigating 1,3-dichloropropene, chloropicrin, and methyl iodide emissions from fumigated soil with reactive film.
Xuan R, Yates SR, Ashworth DJ, Luo L. Xuan R, et al. Environ Sci Technol. 2012 Jun 5;46(11):6143-9. doi: 10.1021/es300388r. Epub 2012 May 11. Environ Sci Technol. 2012. PMID: 22534067
Implicated as a stratospheric ozone-depleting compound, methyl bromide (MeBr) is being phased out despite being considered to be the most effective soil fumigant. Its alternatives, i.e., 1,3-dichloropropene (1,3-D, which includes cis and trans isomers), chloropicrin (CP), …
Implicated as a stratospheric ozone-depleting compound, methyl bromide (MeBr) is being phased out despite being considered to be the most ef …
Effect of formulation on the behavior of 1,3-dichloropropene in soil.
Kim JH, Papiernik SK, Farmer WJ, Gan J, Yates SR. Kim JH, et al. J Environ Qual. 2003 Nov-Dec;32(6):2223-9. doi: 10.2134/jeq2003.2223. J Environ Qual. 2003. PMID: 14674545
Both application methods resulted in the same cumulative emissions for both isomers, 45% for (E)-1,3-D and approximately 50% for (Z)-1,3-D. These results suggest that for drip application of fumigants to be effective in reducing emissions, the fumigant must be applied at s …
Both application methods resulted in the same cumulative emissions for both isomers, 45% for (E)-1,3-D and approximately 50% for (Z)- …
N2,7-bis(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine: identical noncyclic adducts with 1,3-dichloropropene epoxides and methylglyoxal.
Schneider M, Quistad GB, Casida JE. Schneider M, et al. Chem Res Toxicol. 1998 Dec;11(12):1536-42. doi: 10.1021/tx9801256. Chem Res Toxicol. 1998. PMID: 9860499
On the basis of the dGuo model studied here, the DNA adducts of 1, 3-D and its epoxides may be the same as those with methylglyoxal [Vaca, C. E., Fang, J.-L., Conradi, M., and Hou, S.-M. (1994) Carcinogenesis 15, 1887-1894]....
On the basis of the dGuo model studied here, the DNA adducts of 1, 3-D and its epoxides may be the same as those with methylglyoxal [Vaca, C …
Degradation of 1,3-dichloropropene by a soil bacterial consortium and Rhodococcus sp. AS2C isolated from the consortium.
Ou LT, Thomas JE, Chung KY, Ogram AV. Ou LT, et al. Biodegradation. 2001;12(1):39-47. doi: 10.1023/a:1011945023787. Biodegradation. 2001. PMID: 11693294
(Z)-3-chloroallyl alcohol (3-CAA) and (Z)-3-chloroacrylic acid (3-CAAC), and (E)-3-CAA and (E)-3-CAAC were the metabolites of (Z)- and (E)- 1,3-D, respectively. (E)- 1,3-D was degraded faster than (Z)- 1,3-D by the strain AS2C and the consortium. AS2C …
(Z)-3-chloroallyl alcohol (3-CAA) and (Z)-3-chloroacrylic acid (3-CAAC), and (E)-3-CAA and (E)-3-CAAC were the metabolites of …
29 results