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Year Number of Results
1907 1
1913 2
1914 2
1915 2
1916 3
1917 2
1919 2
1920 1
1923 1
1924 4
1925 3
1926 4
1927 6
1928 4
1929 7
1930 6
1931 13
1932 9
1933 9
1934 11
1935 15
1936 15
1937 16
1938 9
1939 9
1940 7
1941 6
1942 6
1943 10
1944 5
1945 91
1946 330
1947 428
1948 470
1949 455
1950 687
1951 822
1952 995
1953 1133
1954 1157
1955 1262
1956 1277
1957 1398
1958 1488
1959 1655
1960 1723
1961 2032
1962 2345
1963 3778
1964 5425
1965 4869
1966 5143
1967 6908
1968 8633
1969 9422
1970 9418
1971 10906
1972 11625
1973 12173
1974 12907
1975 12411
1976 11665
1977 11597
1978 11951
1979 12461
1980 13225
1981 13789
1982 15324
1983 16396
1984 17779
1985 19110
1986 19850
1987 20880
1988 22333
1989 24712
1990 26980
1991 28481
1992 29589
1993 31030
1994 33436
1995 34896
1996 36016
1997 36634
1998 38379
1999 39241
2000 42113
2001 44420
2002 44627
2003 46899
2004 48926
2005 51827
2006 53531
2007 55039
2008 56588
2009 58510
2010 61539
2011 65338
2012 69472
2013 71182
2014 70883
2015 71092
2016 69092
2017 67886
2018 67519
2019 68949
2020 71294
2021 68219
2022 69765
2023 62882
2024 70255
2025 70931
2026 12547

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2,123,420 results

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Page 1
Glycosylation in health and disease.
Reily C, Stewart TJ, Renfrow MB, Novak J. Reily C, et al. Nat Rev Nephrol. 2019 Jun;15(6):346-366. doi: 10.1038/s41581-019-0129-4. Nat Rev Nephrol. 2019. PMID: 30858582 Free PMC article. Review.
The glycome describes the complete repertoire of glycoconjugates composed of carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules. Glycoconjugates are formed through a process called glycosylation and can dif …
The glycome describes the complete repertoire of glycoconjugates composed of carbohydrate chains, or glycans, that are …
Siglec Ligands.
Gonzalez-Gil A, Schnaar RL. Gonzalez-Gil A, et al. Cells. 2021 May 20;10(5):1260. doi: 10.3390/cells10051260. Cells. 2021. PMID: 34065256 Free PMC article. Review.
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan contexts, as their outermost sugar moiety. ...Among the …
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of thes …
Gangliosides as Siglec ligands.
Schnaar RL. Schnaar RL. Glycoconj J. 2023 Apr;40(2):159-167. doi: 10.1007/s10719-023-10101-2. Epub 2023 Jan 26. Glycoconj J. 2023. PMID: 36701102 Free PMC article. Review.
The structure of a sialoglycan can be translated into to a biological response when it binds to a specific endogenous lectin. Among endogenous sialic acid-binding lectins in humans are those comprising the 15-member Siglec family, most of …
The structure of a sialoglycan can be translated into to a biological response when it binds to a specific endogenous lectin. Among e …
Siglec and anti-Siglec therapies.
Murugesan G, Weigle B, Crocker PR. Murugesan G, et al. Curr Opin Chem Biol. 2021 Jun;62:34-42. doi: 10.1016/j.cbpa.2021.01.001. Epub 2021 Feb 16. Curr Opin Chem Biol. 2021. PMID: 33607404 Review.
Siglecs (sialic acid-binding immunoglobulin-like lectins) are a family of receptors that bind sialic acids in specific linkages on glycoproteins and glycolipids. ...In this review, we discuss strategies to target the …
Siglecs (sialic acid-binding immunoglobulin-like lectins) are a family of receptors that bi …
ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment.
Dong X, Wang H, Cai J, Wang Y, Chai D, Sun Z, Chen J, Li M, Xiao T, Shan C, Zhang JV, Yu M. Dong X, et al. J Adv Res. 2025 Jun;72:197-212. doi: 10.1016/j.jare.2024.07.021. Epub 2024 Aug 5. J Adv Res. 2025. PMID: 39111624 Free PMC article.
INTRODUCTION: Embryo implantation requires synergistic interaction between the embryo and the receptive endometrium. Glycoproteins and glycan-binding proteins are involved in endometrium-embryo attachment. Sialyl Tn (sTn), a truncated O-glycan, is cata …
INTRODUCTION: Embryo implantation requires synergistic interaction between the embryo and the receptive endometrium. Glycoproteins and gl …
Siglec functions of microglia.
Linnartz-Gerlach B, Kopatz J, Neumann H. Linnartz-Gerlach B, et al. Glycobiology. 2014 Sep;24(9):794-9. doi: 10.1093/glycob/cwu044. Epub 2014 May 15. Glycobiology. 2014. PMID: 24833613 Review.
Pro-inflammatory immune responses and phagocytosis are turned down in microglia by inhibitory Siglec signaling. Recently, it was demonstrated that inhibitory Siglecs have neuroprotective effects on cultured neurons by preventing the phagocytosis-associated oxidative …
Pro-inflammatory immune responses and phagocytosis are turned down in microglia by inhibitory Siglec signaling. Recently, it was demo …
Human medulloblastoma gangliosides.
Chang F, Li R, Noon K, Gage D, Ladisch S. Chang F, et al. Glycobiology. 1997 Jun;7(4):523-30. doi: 10.1093/glycob/7.4.523. Glycobiology. 1997. PMID: 9184833
To establish a model system for the study of ganglioside metabolism of the human brain tumor, medulloblastoma, we have chemically characterized the gangliosides of the Daoy cell line. ...Isolation of individual gangliosides homogeneous in both carbohydrate …
To establish a model system for the study of ganglioside metabolism of the human brain tumor, medulloblastoma, we have chemically cha …
Galectin-3 interactions with glycosphingolipids.
Collins PM, Bum-Erdene K, Yu X, Blanchard H. Collins PM, et al. J Mol Biol. 2014 Apr 3;426(7):1439-51. doi: 10.1016/j.jmb.2013.12.004. Epub 2013 Dec 8. J Mol Biol. 2014. PMID: 24326249
We present crystallographic structures of the carbohydrate recognition domain of human galectin-3, both wild type and a mutant (K176L) that influenced ligand affinity, in complex with LNT, LNnT and acetamido ganglioside a-GM3 (alpha2,3-sialyllactose …
We present crystallographic structures of the carbohydrate recognition domain of human galectin-3, both wild type and a mutant …
Glycosylation in bladder cancer.
Ohyama C. Ohyama C. Int J Clin Oncol. 2008 Aug;13(4):308-13. doi: 10.1007/s10147-008-0809-8. Epub 2008 Aug 15. Int J Clin Oncol. 2008. PMID: 18704630 Review.
For instance, overexpression of the ganglioside (an acidic glycosphingolipid which has sialic acid) GM3 induces apoptosis and reduces invasive potential in a bladder cancer cell line. ...The expression of N-acetylglucosaminyltransferase V and be …
For instance, overexpression of the ganglioside (an acidic glycosphingolipid which has sialic acid) GM3 induces …
Glycobiology of immune responses.
Rabinovich GA, van Kooyk Y, Cobb BA. Rabinovich GA, et al. Ann N Y Acad Sci. 2012 Apr;1253:1-15. doi: 10.1111/j.1749-6632.2012.06492.x. Ann N Y Acad Sci. 2012. PMID: 22524422 Free PMC article. Review.
Unlike their protein "roommates" and their nucleic acid "cousins," carbohydrates remain an enigmatic arm of biology. The central reason for the difficulty in fully understanding how carbohydrate structure and biological function are tied is the nontemplate na …
Unlike their protein "roommates" and their nucleic acid "cousins," carbohydrates remain an enigmatic arm of biology. The centr …
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