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Quoted phrase not found in phrase index: "infection"
Page 1
Primary brain tumours in adults.
van den Bent MJ, Geurts M, French PJ, Smits M, Capper D, Bromberg JEC, Chang SM. van den Bent MJ, et al. Among authors: geurts m. Lancet. 2023 Oct 28;402(10412):1564-1579. doi: 10.1016/S0140-6736(23)01054-1. Epub 2023 Sep 19. Lancet. 2023. PMID: 37738997 Review.
Targeted treatments based on molecular alterations still only play a minor role in the treatment landscape of adult-type diffuse glioma, and today are mainly limited to patients with tumours with BRAF(V600E) (ie, Val600Glu) mutations. Immunotherapy for CNS tumours is still …
Targeted treatments based on molecular alterations still only play a minor role in the treatment landscape of adult-type diffuse glioma …
H3 K27M-altered glioma and diffuse intrinsic pontine glioma: Semi-systematic review of treatment landscape and future directions.
van den Bent M, Saratsis AM, Geurts M, Franceschi E. van den Bent M, et al. Among authors: geurts m. Neuro Oncol. 2024 May 3;26(Supplement_2):S110-S124. doi: 10.1093/neuonc/noad220. Neuro Oncol. 2024. PMID: 38102230 Free PMC article. Review.
H3 K27M-mutant diffuse glioma is a recently identified brain tumor associated with poor prognosis. As of 2016, it is classified by the World Health Organization as a distinct form of grade IV glioma. ...This review will detail treatment interventions applied to diff …
H3 K27M-mutant diffuse glioma is a recently identified brain tumor associated with poor prognosis. As of 2016, it is classified by th …
A brave new framework for glioma drug development.
Hotchkiss KM, Karschnia P, Schreck KC, Geurts M, Cloughesy TF, Huse J, Duke ES, Lathia J, Ashley DM, Nduom EK, Long G, Singh K, Chalmers A, Ahluwalia MS, Heimberger A, Bagley S, Todo T, Verhaak R, Kelly PD, Hervey-Jumper S, de Groot J, Patel A, Fecci P, Parney I, Wykes V, Watts C, Burns TC, Sanai N, Preusser M, Tonn JC, Drummond KJ, Platten M, Das S, Tanner K, Vogelbaum MA, Weller M, Whittle JR, Berger MS, Khasraw M. Hotchkiss KM, et al. Among authors: geurts m. Lancet Oncol. 2024 Oct;25(10):e512-e519. doi: 10.1016/S1470-2045(24)00190-6. Lancet Oncol. 2024. PMID: 39362262 Free PMC article. Review.
Correcting the drug development paradigm for glioblastoma requires serial tissue sampling.
Singh K, Hotchkiss KM, Parney IF, De Groot J, Sahebjam S, Sanai N, Platten M, Galanis E, Lim M, Wen PY, Minniti G, Colman H, Cloughesy TF, Mehta MP, Geurts M, Arrillaga-Romany I, Desjardins A, Tanner K, Short S, Arons D, Duke E, Wick W, Bagley SJ, Ashley DM, Kumthekar P, Verhaak R, Chalmers AJ, Patel AP, Watts C, Fecci PE, Batchelor TT, Weller M, Vogelbaum MA, Preusser M, Berger MS, Khasraw M. Singh K, et al. Among authors: geurts m. Nat Med. 2023 Oct;29(10):2402-2405. doi: 10.1038/s41591-023-02464-8. Nat Med. 2023. PMID: 37488293 Free PMC article.
A breakthrough in drug discovery for glioblastoma requires serial collection of tissue from the central nervous system via window of opportunity trials...
A breakthrough in drug discovery for glioblastoma requires serial collection of tissue from the central nervous system via window of …
Updated EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection-Update 1.
van den Bent MJ, Franceschi E, Touat M, French PJ, Idbaih A, Lombardi G, Rudà R, Schweizer L, Capper D, Sanson M, Wesseling P, Weller M, Eoli M, Anghileri E, Bielle F, Euskirchen P, Geurts M, Wen PY, Preusser M. van den Bent MJ, et al. Among authors: geurts m. Neuro Oncol. 2025 Feb 10;27(2):331-337. doi: 10.1093/neuonc/noae213. Neuro Oncol. 2025. PMID: 39387386 Free PMC article. Review.
Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis.
Geurts M, Macleod MR, Kollmar R, Kremer PH, van der Worp HB. Geurts M, et al. Crit Care Med. 2014 Feb;42(2):231-42. doi: 10.1097/CCM.0b013e3182a276e8. Crit Care Med. 2014. PMID: 23989182
STUDY SELECTION: We included randomized controlled clinical trials of therapeutic hypothermia induced in adults for any indication, which reported the prevalence of infection in each treatment group. DATA EXTRACTION: For each study, we collected information about the basel …
STUDY SELECTION: We included randomized controlled clinical trials of therapeutic hypothermia induced in adults for any indication, which re …
Treatment of anaplastic gliomas: evidences and controversies.
Geurts M, Snijders TJ, van den Bent MJ. Geurts M, et al. Curr Opin Oncol. 2021 Nov 1;33(6):621-625. doi: 10.1097/CCO.0000000000000785. Curr Opin Oncol. 2021. PMID: 34456249 Review.
RECENT FINDINGS: New biomarkers allow the identification of anaplastic glioma with relatively poor prognosis and with prognosis similar to glioblastoma. An update with molecular analysis of the phase 3 CATNON trial demonstrates the benefit of adjuvant temozolomide ( …
RECENT FINDINGS: New biomarkers allow the identification of anaplastic glioma with relatively poor prognosis and with prognosis simil …
T cell immunity in glioma and potential implications for immunotherapy: A systematic review.
Luning R, French PJ, Vanbilloen WJF, Dobber L, Van Hijfte L, Hoogendijk R, van den Bent MJ, Debets R, Geurts M. Luning R, et al. Among authors: geurts m. Neuro Oncol. 2026 Feb 1;28(2):334-352. doi: 10.1093/neuonc/noaf236. Neuro Oncol. 2026. PMID: 41105161 Free PMC article.
BACKGROUND: T cell-based immunotherapies have had limited success in glioma thus far. Here, we evaluate the literature on abundance, spatial distribution and phenotypical characteristics of T cells in the tumor micro-environment (TME) of IDH-mutant and IDH-wildtype glio …
BACKGROUND: T cell-based immunotherapies have had limited success in glioma thus far. Here, we evaluate the literature on abundance, …
48 results