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Year Number of Results
2012 2
2014 2
2015 6
2016 380
2017 3423
2018 269
2019 7
2021 0
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3,423 results
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Mechanisms of HIV-1 Control.
Soliman M, Srikrishna G, Balagopal A. Soliman M, et al. Curr HIV/AIDS Rep. 2017 Jun;14(3):101-109. doi: 10.1007/s11904-017-0357-9. Curr HIV/AIDS Rep. 2017. PMID: 28466391 Free PMC article. Review.
RECENT FINDINGS: Recent studies of intracellular HIV-1 restriction have offered unique molecular insights into HIV-1 replication and biology. Studies have revealed insights of how restriction factors drive HIV-1 evolution. Although HIV
RECENT FINDINGS: Recent studies of intracellular HIV-1 restriction have offered unique molecular insights into HIV-1
Defining HIV-1 transmission clusters based on sequence data.
Hassan AS, Pybus OG, Sanders EJ, Albert J, Esbjörnsson J. Hassan AS, et al. AIDS. 2017 Jun 1;31(9):1211-1222. doi: 10.1097/QAD.0000000000001470. AIDS. 2017. PMID: 28353537 Free PMC article. Review.
: Understanding HIV-1 transmission dynamics is relevant to both screening and intervention strategies of HIV-1 infection. ...We start by introducing the concepts and methodologies of how HIV-1 transmission clusters usually have been defin …
: Understanding HIV-1 transmission dynamics is relevant to both screening and intervention strategies of HIV-1 i …
How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design.
Pancera M, Changela A, Kwong PD. Pancera M, et al. Curr Opin HIV AIDS. 2017 May;12(3):229-240. doi: 10.1097/COH.0000000000000360. Curr Opin HIV AIDS. 2017. PMID: 28422787 Free PMC article. Review.
PURPOSE OF REVIEW: An HIV-1 vaccine that elicits broadly neutralizing antibodies (bNAbs) remains to be developed. ...RECENT FINDINGS: Isolation of bNAbs from HIV-1-infected donors has led to an unprecedented understanding of the sites of vulnerability …
PURPOSE OF REVIEW: An HIV-1 vaccine that elicits broadly neutralizing antibodies (bNAbs) remains to be developed. ...RECENT FI …
RNA Interference Therapies for an HIV-1 Functional Cure.
Scarborough RJ, Gatignol A. Scarborough RJ, et al. Viruses. 2017 Dec 27;10(1):8. doi: 10.3390/v10010008. Viruses. 2017. PMID: 29280961 Free PMC article. Review.
HIV-1 drug therapies can prevent disease progression but cannot eliminate HIV-1 viruses from an infected individual. ...One of these approaches is the transplant of HIV-1 resistant cells expressing anti-HIV-1 RNAs, proteins
HIV-1 drug therapies can prevent disease progression but cannot eliminate HIV-1 viruses from an infected individ
CRISPR-Cas based antiviral strategies against HIV-1.
Wang G, Zhao N, Berkhout B, Das AT. Wang G, et al. Virus Res. 2018 Jan 15;244:321-332. doi: 10.1016/j.virusres.2017.07.020. Epub 2017 Jul 29. Virus Res. 2018. PMID: 28760348 Free article. Review.
Here, we review how CRISPR-Cas was used in novel therapeutic approaches against the human immunodeficiency virus type-1 (HIV-1), focusing on approaches that aim to permanently inactivate all virus genomes or to prevent viral persistence in latent reservoirs.. …
Here, we review how CRISPR-Cas was used in novel therapeutic approaches against the human immunodeficiency virus type-1 (HIV- …
APOBEC Enzymes as Targets for Virus and Cancer Therapy.
Olson ME, Harris RS, Harki DA. Olson ME, et al. Cell Chem Biol. 2018 Jan 18;25(1):36-49. doi: 10.1016/j.chembiol.2017.10.007. Epub 2017 Nov 16. Cell Chem Biol. 2018. PMID: 29153851 Free PMC article. Review.
APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H restrict human immunodeficiency virus 1 (HIV-1) infection in cells deficient in the viral infectivity factor (Vif), and have the potential to catalyze sublethal levels of mutation in viral genomes in Vif-proficient c …
APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H restrict human immunodeficiency virus 1 (HIV-1) infection in cells deficient …
Current views on the potential for development of a HIV vaccine.
Cohen KW, Frahm N. Cohen KW, et al. Expert Opin Biol Ther. 2017 Mar;17(3):295-303. doi: 10.1080/14712598.2017.1282457. Epub 2017 Jan 23. Expert Opin Biol Ther. 2017. PMID: 28095712 Free PMC article. Review.
Despite many recent advances in the HIV prevention landscape, an effective vaccine remains the most promising tool to end the HIV-1 pandemic. ...This diverse array of vaccine candidates may finally allow us to identify a broadly effective HIV vaccine a …
Despite many recent advances in the HIV prevention landscape, an effective vaccine remains the most promising tool to end the HIV
Transcription: Insights From the HIV-1 Promoter.
Ne E, Palstra RJ, Mahmoudi T. Ne E, et al. Int Rev Cell Mol Biol. 2018;335:191-243. doi: 10.1016/bs.ircmb.2017.07.011. Epub 2017 Oct 12. Int Rev Cell Mol Biol. 2018. PMID: 29305013 Review.
In this review, we cover transcription regulation of human immunodeficiency virus type 1 (HIV-1) gene expression, focusing on the invaluable contributions, made by HIV research over the years, toward the field of transcription. ...The molecular control …
In this review, we cover transcription regulation of human immunodeficiency virus type 1 (HIV-1) gene expression, focus …
CG dinucleotide suppression enables antiviral defence targeting non-self RNA.
Takata MA, Gonçalves-Carneiro D, Zang TM, Soll SJ, York A, Blanco-Melo D, Bieniasz PD. Takata MA, et al. Nature. 2017 Oct 5;550(7674):124-127. doi: 10.1038/nature24039. Epub 2017 Sep 27. Nature. 2017. PMID: 28953888 Free PMC article.
Here we show, using synonymous mutagenesis, that CG suppression is essential for HIV-1 replication. The deleterious effect of CG dinucleotides on HIV-1 replication was cumulative, associated with cytoplasmic RNA depletion, and was exerted by CG dinucle …
Here we show, using synonymous mutagenesis, that CG suppression is essential for HIV-1 replication. The deleterious effect of …
Time Until Emergence of HIV Test Reactivity Following Infection With HIV-1: Implications for Interpreting Test Results and Retesting After Exposure.
Delaney KP, Hanson DL, Masciotra S, Ethridge SF, Wesolowski L, Owen SM. Delaney KP, et al. Clin Infect Dis. 2017 Jan 1;64(1):53-59. doi: 10.1093/cid/ciw666. Epub 2016 Oct 12. Clin Infect Dis. 2017. PMID: 27737954
BACKGROUND: Understanding the period of time between an exposure resulting in infection with human immunodeficiency virus (HIV) and when a test can reliably detect the presence of that infection, that is, the test window period, may benefit testing programs and clinicians …
BACKGROUND: Understanding the period of time between an exposure resulting in infection with human immunodeficiency virus (HIV) and w …
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