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Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours.
Mowday AM, Dubois LJ, Kubiak AM, Chan-Hyams JVE, Guise CP, Ashoorzadeh A, Lambin P, Ackerley DF, Smaill JB, Minton NP, Theys J, Patterson AV. Mowday AM, et al. Among authors: theys j, lambin p. Cancer Gene Ther. 2022 Feb;29(2):178-188. doi: 10.1038/s41417-021-00296-7. Epub 2021 Feb 8. Cancer Gene Ther. 2022. PMID: 33558701
Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress.
Mowday AM, Guise CP, Ackerley DF, Minton NP, Lambin P, Dubois LJ, Theys J, Smaill JB, Patterson AV. Mowday AM, et al. Among authors: theys j, lambin p. Cancers (Basel). 2016 Jun 28;8(7):63. doi: 10.3390/cancers8070063. Cancers (Basel). 2016. PMID: 27367731 Free PMC article. Review.
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