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Year Number of Results
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Page 1
The polymorphisms of the chromatin fiber.
Boulé JB, Mozziconacci J, Lavelle C. Boulé JB, et al. Among authors: lavelle c. J Phys Condens Matter. 2015 Jan 28;27(3):033101. doi: 10.1088/0953-8984/27/3/033101. Epub 2014 Dec 1. J Phys Condens Matter. 2015. PMID: 25437138 Review.
In the emerging picture, the local chromatin state plays a critical role in all fundamental DNA transactions, such as transcriptional control, DNA replication or repair. ...The purpose of this review is to give an overview of the tremendous efforts that have …
In the emerging picture, the local chromatin state plays a critical role in all fundamental DNA transactions, such as transcri …
Chromatin structure and radiation-induced DNA damage: from structural biology to radiobiology.
Lavelle C, Foray N. Lavelle C, et al. Int J Biochem Cell Biol. 2014 Apr;49:84-97. doi: 10.1016/j.biocel.2014.01.012. Epub 2014 Jan 29. Int J Biochem Cell Biol. 2014. PMID: 24486235 Review.
It is now clear that chromatin structure and dynamics play a critical role in all processes involved in DNA metabolism, e.g. replication, transcription, repair and recombination. ...This review focuses on the link between DNA damage and chromatin struc …
It is now clear that chromatin structure and dynamics play a critical role in all processes involved in DNA metabolism, e.g. r …
RNA Nanostructure Molecular Imaging.
Piétrement O, Arluison V, Lavelle C. Piétrement O, et al. Among authors: lavelle c. Methods Mol Biol. 2020;2113:319-327. doi: 10.1007/978-1-0716-0278-2_20. Methods Mol Biol. 2020. PMID: 32006322
Indeed, TEM and AFM analyses permit the conformation of a large population of individual molecular structures to be observed, providing a statistical basis for the variability of these nanostructures within the population. Nevertheless, if double-stranded DNA molecular ima …
Indeed, TEM and AFM analyses permit the conformation of a large population of individual molecular structures to be observed, providing a st …
Nucleosome-remodelling machines and other molecular motors observed at the single-molecule level.
Lavelle C, Praly E, Bensimon D, Le Cam E, Croquette V. Lavelle C, et al. FEBS J. 2011 Oct;278(19):3596-607. doi: 10.1111/j.1742-4658.2011.08280.x. Epub 2011 Sep 8. FEBS J. 2011. PMID: 21810177 Free article. Review.
Through its capability to transiently pack and unpack our genome, chromatin is a key player in the regulation of gene expression. Single-molecule approaches have recently complemented conventional biochemical and biophysical techniques to decipher the complex mechanisms ru …
Through its capability to transiently pack and unpack our genome, chromatin is a key player in the regulation of gene expression. Sin …
Chromatin fiber dynamics under tension and torsion.
Lavelle C, Victor JM, Zlatanova J. Lavelle C, et al. Int J Mol Sci. 2010 Apr 12;11(4):1557-79. doi: 10.3390/ijms11041557. Int J Mol Sci. 2010. PMID: 20480035 Free PMC article. Review.
Genetic and epigenetic information in eukaryotic cells is carried on chromosomes, basically consisting of large compact supercoiled chromatin fibers. Micromanipulations have recently led to great advances in the knowledge of the complex mechanisms underlying the regulation …
Genetic and epigenetic information in eukaryotic cells is carried on chromosomes, basically consisting of large compact supercoiled chrom
Pack, unpack, bend, twist, pull, push: the physical side of gene expression.
Lavelle C. Lavelle C. Curr Opin Genet Dev. 2014 Apr;25:74-84. doi: 10.1016/j.gde.2014.01.001. Epub 2014 Feb 25. Curr Opin Genet Dev. 2014. PMID: 24576847 Review.
Molecular motors such as polymerases produce physical constraints on DNA and chromatin. Recent techniques, in particular single-molecule micromanipulation, provide estimation of the forces and torques at stake. These biophysical approaches have improved our understa …
Molecular motors such as polymerases produce physical constraints on DNA and chromatin. Recent techniques, in particular singl …
A fractal model for nuclear organization: current evidence and biological implications.
Bancaud A, Lavelle C, Huet S, Ellenberg J. Bancaud A, et al. Among authors: lavelle c. Nucleic Acids Res. 2012 Oct;40(18):8783-92. doi: 10.1093/nar/gks586. Epub 2012 Jul 11. Nucleic Acids Res. 2012. PMID: 22790985 Free PMC article. Review.
Chromatin is a multiscale structure on which transcription, replication, recombination and repair of the genome occur. To fully understand any of these processes at the molecular level under physiological conditions, a clear picture of the polymorphic and dynamic organizat
Chromatin is a multiscale structure on which transcription, replication, recombination and repair of the genome occur. To fully under
Relevance and limitations of crowding, fractal, and polymer models to describe nuclear architecture.
Huet S, Lavelle C, Ranchon H, Carrivain P, Victor JM, Bancaud A. Huet S, et al. Among authors: lavelle c. Int Rev Cell Mol Biol. 2014;307:443-79. doi: 10.1016/B978-0-12-800046-5.00013-8. Int Rev Cell Mol Biol. 2014. PMID: 24380602 Review.
In this review our goal is to survey several nonmutually exclusive models that have emerged to describe the folding of DNA in the nucleus, the dynamics of proteins in the nucleoplasm, or the movements of chromosome loci. ...
In this review our goal is to survey several nonmutually exclusive models that have emerged to describe the folding of DNA in the nuc …
Forces and torques in the nucleus: chromatin under mechanical constraints.
Lavelle C. Lavelle C. Biochem Cell Biol. 2009 Feb;87(1):307-22. doi: 10.1139/O08-123. Biochem Cell Biol. 2009. PMID: 19234543 Review.
Through dynamic changes in structure, resulting from chemical modifications and mechanical constraints imposed by numerous factors in vivo, chromatin plays a critical role in the regulation of DNA metabolism processes, including replication and transcription. Indeed …
Through dynamic changes in structure, resulting from chemical modifications and mechanical constraints imposed by numerous factors in vivo, …
36 results