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Page 1
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mejía-Vilet JM, Nester CM, Radhakrishnan J, Rave EM, Reich HN, Ronco P, Sanders JF, Sethi S, Suzuki Y, Tang SCW, Tesar V, Vivarelli M, Wetzels JFM, Lytvyn L, Craig JC, Tunnicliffe DJ, Howell M, Tonelli MA, Cheung M, Earley A, Floege J. Rovin BH, et al. Kidney Int. 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015. Kidney Int. 2021. PMID: 34556300 Free article.
The scope includes various glomerular diseases, including IgA nephropathy and IgA vasculitis, membranous nephropathy, nephrotic syndrome, minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), infection-related GN, antineutrophil cytoplasmic antibody (ANCA) vasc …
The scope includes various glomerular diseases, including IgA nephropathy and IgA vasculitis, membranous nephropathy, nephrotic syndrome, mi …
Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC. Sethi S, et al. Lancet. 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. Lancet. 2022. PMID: 35461559 Review.
As such, glomerulonephritis can be broadly classified as immune-complex glomerulonephritis (including infection-related glomerulonephritis, IgA nephropathy, lupus nephritis, and cryoglobulinaemic glomerulonephritis), anti-neutrophil cytoplasmic antibodies-associated …
As such, glomerulonephritis can be broadly classified as immune-complex glomerulonephritis (including infection-related glomerulonephritis, …
Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.
Bajema IM, Wilhelmus S, Alpers CE, Bruijn JA, Colvin RB, Cook HT, D'Agati VD, Ferrario F, Haas M, Jennette JC, Joh K, Nast CC, Noël LH, Rijnink EC, Roberts ISD, Seshan SV, Sethi S, Fogo AB. Bajema IM, et al. Kidney Int. 2018 Apr;93(4):789-796. doi: 10.1016/j.kint.2017.11.023. Epub 2018 Feb 16. Kidney Int. 2018. PMID: 29459092 Free article.
We present a consensus report pertaining to the improved clarity of definitions and classification of glomerular lesions in lupus nephritis that derived from a meeting of 18 members of an international nephropathology working group in Leiden, Netherlands, in 2016. . …
We present a consensus report pertaining to the improved clarity of definitions and classification of glomerular lesions in lupus …
Lupus Vasculitis.
Calle-Botero E, Abril A. Calle-Botero E, et al. Curr Rheumatol Rep. 2020 Aug 26;22(10):71. doi: 10.1007/s11926-020-00937-0. Curr Rheumatol Rep. 2020. PMID: 32845454 Review.
As a multisystem autoimmune disease, systemic lupus may attack practically any organ system in the human body. ...RECENT FINDINGS: Recent findings regarding the pathogenesis of lupus CNS and peripheral nerve disease, and vascular injury in lupus nephritis …
As a multisystem autoimmune disease, systemic lupus may attack practically any organ system in the human body. ...RECENT FINDINGS: Re …
Standardized classification and reporting of glomerulonephritis.
Sethi S, Fervenza FC. Sethi S, et al. Nephrol Dial Transplant. 2019 Feb 1;34(2):193-199. doi: 10.1093/ndt/gfy220. Nephrol Dial Transplant. 2019. PMID: 30124958 Review.
Immune complex GN includes multiple specific diseases such as lupus nephritis, IgA nephropathy, infection-related GN and fibrillary GN. ...
Immune complex GN includes multiple specific diseases such as lupus nephritis, IgA nephropathy, infection-related GN and fibri …
Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.
Sethi S, Madden BJ, Debiec H, Charlesworth MC, Gross L, Ravindran A, Hummel AM, Specks U, Fervenza FC, Ronco P. Sethi S, et al. J Am Soc Nephrol. 2019 Jun;30(6):1123-1136. doi: 10.1681/ASN.2018080852. Epub 2019 May 6. J Am Soc Nephrol. 2019. PMID: 31061139 Free PMC article.
Clinical and biopsy findings showed features of autoimmune disease, including lupus, in 80.7% of the 26 EXT1/EXT2-associated MN cases we identified. In the validation cohort, we confirmed that EXT1/EXT2 staining was detected in pure class 5 lupus nephritis (e …
Clinical and biopsy findings showed features of autoimmune disease, including lupus, in 80.7% of the 26 EXT1/EXT2-associated MN cases …
Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN.
Sethi S, Haas M, Markowitz GS, D'Agati VD, Rennke HG, Jennette JC, Bajema IM, Alpers CE, Chang A, Cornell LD, Cosio FG, Fogo AB, Glassock RJ, Hariharan S, Kambham N, Lager DJ, Leung N, Mengel M, Nath KA, Roberts IS, Rovin BH, Seshan SV, Smith RJ, Walker PD, Winearls CG, Appel GB, Alexander MP, Cattran DC, Casado CA, Cook HT, De Vriese AS, Radhakrishnan J, Racusen LC, Ronco P, Fervenza FC. Sethi S, et al. J Am Soc Nephrol. 2016 May;27(5):1278-87. doi: 10.1681/ASN.2015060612. Epub 2015 Nov 13. J Am Soc Nephrol. 2016. PMID: 26567243 Free PMC article.
The primary diagnosis should include the disease entity/pathogenic type (if disease entity is not known) followed in order by pattern of injury (mixed patterns may be present); score/grade/class for disease entities, such as IgA nephropathy, lupus nephritis, and ANC …
The primary diagnosis should include the disease entity/pathogenic type (if disease entity is not known) followed in order by pattern of inj …
Pregnancy and Lupus Nephritis.
Kattah AG, Garovic VD. Kattah AG, et al. Semin Nephrol. 2015 Sep;35(5):487-99. doi: 10.1016/j.semnephrol.2015.08.010. Semin Nephrol. 2015. PMID: 26573551 Review.
The management of lupus nephritis in pregnancy presents a diagnostic and therapeutic challenge for providers. ...
The management of lupus nephritis in pregnancy presents a diagnostic and therapeutic challenge for providers. ...
Immunofluorescence staining for immunoglobulin heavy chain/light chain on kidney biopsies is a valuable ancillary technique for the diagnosis of monoclonal gammopathy-associated kidney diseases.
Nasr SH, Fidler ME, Said SM, Koepplin JW, Altamirano-Alonso JM, Leung N. Nasr SH, et al. Kidney Int. 2021 Jul;100(1):155-170. doi: 10.1016/j.kint.2021.02.038. Epub 2021 Mar 25. Kidney Int. 2021. PMID: 33774084
The sensitivity and specificity of HLC immunofluorescence was confirmed by testing cases of lupus nephritis, other polyclonal immunoglobulin nephropathies, and light chain nephropathies (light chain amyloidosis and deposition disease). ...
The sensitivity and specificity of HLC immunofluorescence was confirmed by testing cases of lupus nephritis, other polyclonal …
Treatments for Lupus Nephritis: A Systematic Review and Network Metaanalysis.
Singh JA, Hossain A, Kotb A, Oliveira A, Mudano AS, Grossman J, Winthrop K, Wells GA. Singh JA, et al. J Rheumatol. 2016 Oct;43(10):1801-1815. doi: 10.3899/jrheum.160041. Epub 2016 Sep 1. J Rheumatol. 2016. PMID: 27585688 Free article. Review.
OBJECTIVE: To compare benefits and harms of lupus nephritis (LN) induction and maintenance treatments. METHODS: We performed a systematic review and Bayesian network metaanalyses of randomized controlled trials (RCT) of immunosuppressive drugs or corticosteroids (CS …
OBJECTIVE: To compare benefits and harms of lupus nephritis (LN) induction and maintenance treatments. METHODS: We performed a …
72 results