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Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.
Bajema IM, Wilhelmus S, Alpers CE, Bruijn JA, Colvin RB, Cook HT, D'Agati VD, Ferrario F, Haas M, Jennette JC, Joh K, Nast CC, Noël LH, Rijnink EC, Roberts ISD, Seshan SV, Sethi S, Fogo AB. Bajema IM, et al. Kidney Int. 2018 Apr;93(4):789-796. doi: 10.1016/j.kint.2017.11.023. Epub 2018 Feb 16. Kidney Int. 2018. PMID: 29459092 Free article.
We present a consensus report pertaining to the improved clarity of definitions and classification of glomerular lesions in lupus nephritis that derived from a meeting of 18 members of an international nephropathology working group in Leiden, Netherlands, in 2016. . …
We present a consensus report pertaining to the improved clarity of definitions and classification of glomerular lesions in lupus …
Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC. Sethi S, et al. Lancet. 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. Lancet. 2022. PMID: 35461559 Review.
As such, glomerulonephritis can be broadly classified as immune-complex glomerulonephritis (including infection-related glomerulonephritis, IgA nephropathy, lupus nephritis, and cryoglobulinaemic glomerulonephritis), anti-neutrophil cytoplasmic antibodies-associated …
As such, glomerulonephritis can be broadly classified as immune-complex glomerulonephritis (including infection-related glomerulonephritis, …
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mejía-Vilet JM, Nester CM, Radhakrishnan J, Rave EM, Reich HN, Ronco P, Sanders JF, Sethi S, Suzuki Y, Tang SCW, Tesar V, Vivarelli M, Wetzels JFM, Lytvyn L, Craig JC, Tunnicliffe DJ, Howell M, Tonelli MA, Cheung M, Earley A, Floege J. Rovin BH, et al. Kidney Int. 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015. Kidney Int. 2021. PMID: 34556300 Free article.
The scope includes various glomerular diseases, including IgA nephropathy and IgA vasculitis, membranous nephropathy, nephrotic syndrome, minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), infection-related GN, antineutrophil cytoplasmic antibody (ANCA) vasc …
The scope includes various glomerular diseases, including IgA nephropathy and IgA vasculitis, membranous nephropathy, nephrotic syndrome, mi …
Lupus Vasculitis.
Calle-Botero E, Abril A. Calle-Botero E, et al. Curr Rheumatol Rep. 2020 Aug 26;22(10):71. doi: 10.1007/s11926-020-00937-0. Curr Rheumatol Rep. 2020. PMID: 32845454 Review.
As a multisystem autoimmune disease, systemic lupus may attack practically any organ system in the human body. Even though vasculitis is not the most common presentation or pathogenic mechanism of disease, it frequently causes significant morbidity and mortality in patient …
As a multisystem autoimmune disease, systemic lupus may attack practically any organ system in the human body. Even though vasculitis …
Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.
Sethi S, Madden BJ, Debiec H, Charlesworth MC, Gross L, Ravindran A, Hummel AM, Specks U, Fervenza FC, Ronco P. Sethi S, et al. J Am Soc Nephrol. 2019 Jun;30(6):1123-1136. doi: 10.1681/ASN.2018080852. Epub 2019 May 6. J Am Soc Nephrol. 2019. PMID: 31061139 Free PMC article.
We also evaluated 48 cases of PLA2R-negative presumed primary MN and lupus MN in a validation cohort. We used laser microdissection and mass spectrometry to identify new antigens, which were localized by immunohistochemistry. ...Clinical and biopsy findings showed features …
We also evaluated 48 cases of PLA2R-negative presumed primary MN and lupus MN in a validation cohort. We used laser microdissection a …
Standardized classification and reporting of glomerulonephritis.
Sethi S, Fervenza FC. Sethi S, et al. Nephrol Dial Transplant. 2019 Feb 1;34(2):193-199. doi: 10.1093/ndt/gfy220. Nephrol Dial Transplant. 2019. PMID: 30124958 Review.
Immune complex GN includes multiple specific diseases such as lupus nephritis, IgA nephropathy, infection-related GN and fibrillary GN. ANCA GN, anti-GBM GN and C3 glomerulopathy are specific diseases in themselves, while monoclonal Ig GN includes proliferative GN w …
Immune complex GN includes multiple specific diseases such as lupus nephritis, IgA nephropathy, infection-related GN and fibri …
Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN.
Sethi S, Haas M, Markowitz GS, D'Agati VD, Rennke HG, Jennette JC, Bajema IM, Alpers CE, Chang A, Cornell LD, Cosio FG, Fogo AB, Glassock RJ, Hariharan S, Kambham N, Lager DJ, Leung N, Mengel M, Nath KA, Roberts IS, Rovin BH, Seshan SV, Smith RJ, Walker PD, Winearls CG, Appel GB, Alexander MP, Cattran DC, Casado CA, Cook HT, De Vriese AS, Radhakrishnan J, Racusen LC, Ronco P, Fervenza FC. Sethi S, et al. J Am Soc Nephrol. 2016 May;27(5):1278-87. doi: 10.1681/ASN.2015060612. Epub 2015 Nov 13. J Am Soc Nephrol. 2016. PMID: 26567243 Free PMC article.
The primary diagnosis should include the disease entity/pathogenic type (if disease entity is not known) followed in order by pattern of injury (mixed patterns may be present); score/grade/class for disease entities, such as IgA nephropathy, lupus nephritis, and ANC …
The primary diagnosis should include the disease entity/pathogenic type (if disease entity is not known) followed in order by pattern of inj …
Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy.
Barbour SJ, Fervenza FC, Induruwage D, Brenchley PE, Rovin B, Hladunewich MA, Reich HN, Lafayette R, Aslam N, Appel GB, Zand L, Kiryluk K, Liu L, Cattran DC; MENTOR Trial Investigators. Barbour SJ, et al. Clin J Am Soc Nephrol. 2023 Oct 1;18(10):1283-1293. doi: 10.2215/CJN.0000000000000237. Epub 2023 Jul 20. Clin J Am Soc Nephrol. 2023. PMID: 37471101
Pregnancy and Lupus Nephritis.
Kattah AG, Garovic VD. Kattah AG, et al. Semin Nephrol. 2015 Sep;35(5):487-99. doi: 10.1016/j.semnephrol.2015.08.010. Semin Nephrol. 2015. PMID: 26573551 Review.
The management of lupus nephritis in pregnancy presents a diagnostic and therapeutic challenge for providers. ...
The management of lupus nephritis in pregnancy presents a diagnostic and therapeutic challenge for providers. ...
Genetics of human lupus nephritis.
Iwamoto T, Niewold TB. Iwamoto T, et al. Clin Immunol. 2017 Dec;185:32-39. doi: 10.1016/j.clim.2016.09.012. Epub 2016 Sep 28. Clin Immunol. 2017. PMID: 27693588 Free PMC article. Review.
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by immune complex formation with multi-organ manifestations. Lupus nephritis (LN) is one of the most severe types of organ damage in SLE, and it clearly contributes to incr …
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by immune complex formation with multi-organ m …
82 results