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211 results

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Page 1
Diabetic macular edema: Evidence-based management.
Browning DJ, Stewart MW, Lee C. Browning DJ, et al. Indian J Ophthalmol. 2018 Dec;66(12):1736-1750. doi: 10.4103/ijo.IJO_1240_18. Indian J Ophthalmol. 2018. PMID: 30451174 Free PMC article. Review.
Diabetic macular edema (DME) is the most common cause of vision loss in patients with diabetic retinopathy with an increasing prevalence tied to the global epidemic in type 2 diabetes mellitus. ...
Diabetic macular edema (DME) is the most common cause of vision loss in patients with diabetic retinopathy with an increasing prevale …
Macular neovascularization.
Sheth JU, Stewart MW, Narayanan R, Anantharaman G, Chandran K, Lai TYY, Chakravarthy U, Das T. Sheth JU, et al. Surv Ophthalmol. 2025 Jul-Aug;70(4):653-675. doi: 10.1016/j.survophthal.2024.08.003. Epub 2024 Aug 31. Surv Ophthalmol. 2025. PMID: 39222802 Review.
Neovascularization of the macula, a common complication of many chorioretinal diseases such as neovascular age-related macular degeneration, polypoidal choroidal vasculopathy, and pathologic myopia, results from increased synthesis of vascular endothelial growth fac …
Neovascularization of the macula, a common complication of many chorioretinal diseases such as neovascular age-related macular deg
Geographic atrophy: Mechanism of disease, pathophysiology, and role of the complement system.
Bakri SJ, Bektas M, Sharp D, Luo R, Sarda SP, Khan S. Bakri SJ, et al. J Manag Care Spec Pharm. 2023 May;29(5-a Suppl):S2-S11. doi: 10.18553/jmcp.2023.29.5-a.s2. J Manag Care Spec Pharm. 2023. PMID: 37125931 Free PMC article.
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD), characterized by atrophic lesions that first start in the outer retina and progressively expand to cover the macula and the fovea, the center of the macula, leading to irreversibl …
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD), characterized by atrophic lesions that …
Paraproteinemic maculopathy.
Mansour AM, Arevalo JF, Badal J, Moorthy RS, Shah GK, Zegarra H, Pulido JS, Charbaji A, Amselem L, Lavaque AJ, Casella A, Ahmad B, Paschall JG, Caimi A, Staurenghi G. Mansour AM, et al. Ophthalmology. 2014 Oct;121(10):1925-32. doi: 10.1016/j.ophtha.2014.04.007. Epub 2014 Jun 18. Ophthalmology. 2014. PMID: 24950591
PURPOSE: Paraproteinemia relates to monoclonal gammopathy-producing pathologic antibodies with serous macular detachment being an uncommon ocular manifestation. We ascertained the clinical course of maculopathy in paraproteinemia and investigated the effect of various ther …
PURPOSE: Paraproteinemia relates to monoclonal gammopathy-producing pathologic antibodies with serous macular detachment being an unc …
The IGF System and Aging.
Conover CA, Oxvig C. Conover CA, et al. Endocr Rev. 2025 Mar 11;46(2):214-223. doi: 10.1210/endrev/bnae029. Endocr Rev. 2025. PMID: 39418083 Free PMC article. Review.
This review will briefly describe the different components of the IGF system and then discuss past and current literature regarding IGF and aging, with a focus on cellular senescence, model organisms of aging, centenarian genetics, and 3 age-related diseases-pulmonary fibrosis, A …
This review will briefly describe the different components of the IGF system and then discuss past and current literature regarding IGF and …
Submacular Hemorrhage Rates Following Anti-Vascular Endothelial Growth Factor Injections for Exudative Age-Related Macular Degeneration.
Kaufmann GT, Boucher N, Sharma C, Aggarwal N, Starr MR. Kaufmann GT, et al. Am J Ophthalmol. 2025 Feb;270:172-182. doi: 10.1016/j.ajo.2024.10.017. Epub 2024 Oct 23. Am J Ophthalmol. 2025. PMID: 39455036
METHODS: All patients in the database from January 2015 to November 2023 with a diagnosis of neovascular age-related macular degeneration and accompanying submacular hemorrhage (SMH). SMH prevalence and associated anti-VEGF injection type were analyzed in 140,915 ey …
METHODS: All patients in the database from January 2015 to November 2023 with a diagnosis of neovascular age-related macular degen
Longitudinal Retinal Changes in MOGAD.
Oertel FC, Sotirchos ES, Zimmermann HG, Motamedi S, Specovius S, Asseyer ES, Chien C, Cook L, Vasileiou E, Filippatou A, Calabresi PA, Saidha S, Pandit L, D'Cunha A, Outteryck O, Zéphir H, Pittock S, Flanagan EP, Bhatti MT, Rommer PS, Bsteh G, Zrzavy T, Kuempfel T, Aktas O, Ringelstein M, Albrecht P, Ayzenberg I, Pakeerathan T, Knier B, Aly L, Asgari N, Soelberg K, Marignier R, Tilikete CF, Cobo Calvo A, Villoslada P, Sanchez-Dalmau B, Martinez-Lapiscina EH, Llufriu S, Green AJ, Yeaman MR, Smith TJ, Brandt AU, Chen J, Paul F, Havla J; with the GJCF International Clinical Consortium for NMOSD and the CROCTINO study group. Oertel FC, et al. Ann Neurol. 2022 Sep;92(3):476-485. doi: 10.1002/ana.26440. Epub 2022 Jul 16. Ann Neurol. 2022. PMID: 35703428 Free article.
OCT data was acquired with (1) Spectralis spectral domain OCT (MOGAD: N = 66 and HCs: N = 103) and (2) Cirrus high-definition OCT (MOGAD: N = 14 and HCs: N = 36). Macular combined ganglion cell and inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer ( …
OCT data was acquired with (1) Spectralis spectral domain OCT (MOGAD: N = 66 and HCs: N = 103) and (2) Cirrus high-definition OCT (MOGAD: N …
Artificial intelligence in ophthalmology.
Khossravi AS, Chen Q, Adelman RA. Khossravi AS, et al. Curr Opin Ophthalmol. 2025 Jan 1;36(1):35-38. doi: 10.1097/ICU.0000000000001111. Epub 2024 Nov 27. Curr Opin Ophthalmol. 2025. PMID: 39607311 Review.
In ocular health diagnosis and treatment of diabetic retinopathy, macular degeneration, glaucoma, corneal infections, and ectasia are only a few examples of how the power of artificial intelligence has been harnessed. ...
In ocular health diagnosis and treatment of diabetic retinopathy, macular degeneration, glaucoma, corneal infections, and ecta …
Recent Updates on the Diagnosis and Management of Age-Related Macular Degeneration.
Boopathiraj N, Wagner IV, Dorairaj SK, Miller DD, Stewart MW. Boopathiraj N, et al. Mayo Clin Proc Innov Qual Outcomes. 2024 Jun 26;8(4):364-374. doi: 10.1016/j.mayocpiqo.2024.05.003. eCollection 2024 Aug. Mayo Clin Proc Innov Qual Outcomes. 2024. PMID: 39036487 Free PMC article.
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the Western world, with a higher prevalence among Europeans and North Americans than that in Africans, Hispanics, and Asians. ...We searched PubMed and Medline databases from Ja …
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the Western world, with a higher prev …
Metabolic syndrome and the aging retina.
Roddy GW. Roddy GW. Curr Opin Ophthalmol. 2021 May 1;32(3):280-287. doi: 10.1097/ICU.0000000000000747. Curr Opin Ophthalmol. 2021. PMID: 33630786 Review.
PURPOSE OF REVIEW: This review explores metabolic syndrome (MetS) as a risk factor that accelerates aging in retinal neurons and may contribute to the neurodegeneration seen in glaucomatous optic neuropathy (GON) and age-related macular degeneration (AMD). RECENT FI …
PURPOSE OF REVIEW: This review explores metabolic syndrome (MetS) as a risk factor that accelerates aging in retinal neurons and may contrib …
211 results