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312 results

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Page 1
Multiple myeloma.
Kumar SK, Rajkumar V, Kyle RA, van Duin M, Sonneveld P, Mateos MV, Gay F, Anderson KC. Kumar SK, et al. Nat Rev Dis Primers. 2017 Jul 20;3:17046. doi: 10.1038/nrdp.2017.46. Nat Rev Dis Primers. 2017. PMID: 28726797 Review.
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ …
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of …
Monoclonal Gammopathy of Undetermined Significance.
Gonsalves WI, Rajkumar SV. Gonsalves WI, et al. Ann Intern Med. 2022 Dec;175(12):ITC177-ITC192. doi: 10.7326/AITC202212200. Epub 2022 Dec 13. Ann Intern Med. 2022. PMID: 36508741 Review.
Monoclonal gammopathy of undetermined significance (MGUS) is of considerable clinical importance to primary care physicians given its high prevalence in the general population. ...In addition, MGUS has been associated with several nonmalignant y …
Monoclonal gammopathy of undetermined significance (MGUS) is of considerable clinical importance to prima …
Cutaneous manifestations of monoclonal gammopathy.
Claveau JS, Wetter DA, Kumar S. Claveau JS, et al. Blood Cancer J. 2022 Apr 11;12(4):58. doi: 10.1038/s41408-022-00661-1. Blood Cancer J. 2022. PMID: 35411042 Free PMC article. Review.
Monoclonal gammopathy associated with dermatological manifestations are a well-recognized complication. These skin disorders can be associated with infiltration and proliferation of a malignant plasma cells or by a deposition of the monoclonal immunoglobulin …
Monoclonal gammopathy associated with dermatological manifestations are a well-recognized complication. These skin disorders c …
Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance.
Kyle RA, Larson DR, Therneau TM, Dispenzieri A, Kumar S, Cerhan JR, Rajkumar SV. Kyle RA, et al. N Engl J Med. 2018 Jan 18;378(3):241-249. doi: 10.1056/NEJMoa1709974. N Engl J Med. 2018. PMID: 29342381 Free PMC article.
BACKGROUND: Monoclonal gammopathy of undetermined significance (MGUS) occurs in approximately 3% of persons 50 years of age or older. ...Among patients with IgM MGUS, the presence of two adverse risk factors - namely, an abnormal serum free ligh …
BACKGROUND: Monoclonal gammopathy of undetermined significance (MGUS) occurs in approximately 3% of perso …
Monoclonal Gammopathy-Associated Peripheral Neuropathy: Diagnosis and Management.
Chaudhry HM, Mauermann ML, Rajkumar SV. Chaudhry HM, et al. Mayo Clin Proc. 2017 May;92(5):838-850. doi: 10.1016/j.mayocp.2017.02.003. Mayo Clin Proc. 2017. PMID: 28473042 Free PMC article. Review.
Monoclonal gammopathies comprise a spectrum of clonal plasma cell disorders that include monoclonal gammopathy of undetermined significance, multiple myeloma, and Waldenstrom macroglobulinemia. In this review, we outline the epidemiology, …
Monoclonal gammopathies comprise a spectrum of clonal plasma cell disorders that include monoclonal gammopathy of …
Renal manifestations of MGUS.
Bridoux F, Nasr SH, Arnulf B, Leung N, Sirac C, Jaccard A. Bridoux F, et al. Hematology Am Soc Hematol Educ Program. 2024 Dec 6;2024(1):489-498. doi: 10.1182/hematology.2024000573. Hematology Am Soc Hematol Educ Program. 2024. PMID: 39644070 Free PMC article. Review.
Kidney disease is a common complication of monoclonal immunoglobulin (MIg)-secreting B-cell disorders and predominantly occurs in patients who do not meet the criteria for an overt hematological disease. To distinguish this situation from monoclonal gammopathy …
Kidney disease is a common complication of monoclonal immunoglobulin (MIg)-secreting B-cell disorders and predominantly occurs in pat …
Smoldering multiple myeloma current treatment algorithms.
Rajkumar SV, Kumar S, Lonial S, Mateos MV. Rajkumar SV, et al. Blood Cancer J. 2022 Sep 5;12(9):129. doi: 10.1038/s41408-022-00719-0. Blood Cancer J. 2022. PMID: 36064707 Free PMC article. Review.
Smoldering multiple myeloma (SMM) is an asymptomatic condition that occupies a space between monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) along the spectrum of clonal plasma cell proliferative disorders. .. …
Smoldering multiple myeloma (SMM) is an asymptomatic condition that occupies a space between monoclonal gammopathy of …
Diagnosis of monoclonal gammopathy of renal significance.
Bridoux F, Leung N, Hutchison CA, Touchard G, Sethi S, Fermand JP, Picken MM, Herrera GA, Kastritis E, Merlini G, Roussel M, Fervenza FC, Dispenzieri A, Kyle RA, Nasr SH; International Kidney and Monoclonal Gammopathy Research Group. Bridoux F, et al. Kidney Int. 2015 Apr;87(4):698-711. doi: 10.1038/ki.2014.408. Epub 2015 Jan 21. Kidney Int. 2015. PMID: 25607108 Free article. Review.
Monoclonal gammopathy of renal significance (MGRS) regroups all renal disorders caused by a monoclonal immunoglobulin (MIg) secreted by a nonmalignant B-cell clone. By definition, patients with MGRS do not meet the criteria for overt multiple myeloma/B …
Monoclonal gammopathy of renal significance (MGRS) regroups all renal disorders caused by a monoclonal immunoglo …
Smoldering multiple myeloma.
Rajkumar SV, Landgren O, Mateos MV. Rajkumar SV, et al. Blood. 2015 May 14;125(20):3069-75. doi: 10.1182/blood-2014-09-568899. Epub 2015 Apr 2. Blood. 2015. PMID: 25838344 Free PMC article. Review.
Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder. SMM is distinguished from monoclonal gammopathy of undetermined significance by a much higher risk of progression to multiple myeloma (MM). ...Importantly, a subse …
Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder. SMM is distinguished from monoclonal gammopathy …
Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management.
Kyle RA, Durie BG, Rajkumar SV, Landgren O, Blade J, Merlini G, Kröger N, Einsele H, Vesole DH, Dimopoulos M, San Miguel J, Avet-Loiseau H, Hajek R, Chen WM, Anderson KC, Ludwig H, Sonneveld P, Pavlovsky S, Palumbo A, Richardson PG, Barlogie B, Greipp P, Vescio R, Turesson I, Westin J, Boccadoro M; International Myeloma Working Group. Kyle RA, et al. Leukemia. 2010 Jun;24(6):1121-7. doi: 10.1038/leu.2010.60. Epub 2010 Apr 22. Leukemia. 2010. PMID: 20410922 Free PMC article. Review.
Monoclonal gammopathy of undetermined significance (MGUS) was identified in 3.2% of 21 463 residents of Olmsted County, Minnesota, 50 years of age or older. ...
Monoclonal gammopathy of undetermined significance (MGUS) was identified in 3.2% of 21 463 residents of O …
312 results