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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 2
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2007 3
2008 3
2009 4
2010 7
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142 results

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Page 1
Oral phytate supplementation on the progression of mild cognitive impairment, brain iron deposition and diabetic retinopathy in patients with type 2 diabetes: a concept paper for a randomized double blind placebo controlled trial (the PHYND trial).
Pujol A, Sanchis P, Tamayo MI, Nicolau J, Grases F, Espino A, Estremera A, Rigo E, Amengual GJ, Rodríguez M, Ribes JL, Gomila I, Simó-Servat O, Masmiquel L. Pujol A, et al. Front Endocrinol (Lausanne). 2024 May 30;15:1332237. doi: 10.3389/fendo.2024.1332237. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38872972 Free PMC article. Clinical Trial.
Diary phytate intake might reduce the micro- and macrovascular complications of patients with type 2 diabetes mellitus through different mechanisms. We describe the protocol of the first trial (the PHYND trial) that evaluate the effect of daily phytate supplementati …
Diary phytate intake might reduce the micro- and macrovascular complications of patients with type 2 diabetes mellitus through different mec …
The Irony of Iron: The Element with Diverse Influence on Neurodegenerative Diseases.
Lee S, Kovacs GG. Lee S, et al. Int J Mol Sci. 2024 Apr 12;25(8):4269. doi: 10.3390/ijms25084269. Int J Mol Sci. 2024. PMID: 38673855 Free PMC article. Review.
Iron accumulation in the brain is a common feature of many neurodegenerative diseases. ...Understanding of disease-related iron accumulation at a more intricate and systemic level is critical for advancements in iron chelation therapies..
Iron accumulation in the brain is a common feature of many neurodegenerative diseases. ...Understanding of disease-rela
Melatonin: a ferroptosis inhibitor with potential therapeutic efficacy for the post-COVID-19 trajectory of accelerated brain aging and neurodegeneration.
Yehia A, Abulseoud OA. Yehia A, et al. Mol Neurodegener. 2024 Apr 19;19(1):36. doi: 10.1186/s13024-024-00728-6. Mol Neurodegener. 2024. PMID: 38641847 Free PMC article. Review.
Ferroptosis, an iron-dependent cell death, is a strongly proposed underlying mechanism in post-COVID-19 aging and neurodegeneration discourse. COVID-19 incites neuroinflammation, iron dysregulation, reactive oxygen species (ROS) accumulation, antioxida …
Ferroptosis, an iron-dependent cell death, is a strongly proposed underlying mechanism in post-COVID-19 aging and neurodegeneratio
Acetylated oligopeptide and N-acetylcysteine protect against iron overload-induced dentate gyrus hippocampal degeneration through upregulation of Nestin and Nrf2/HO-1 and downregulation of MMP-9/TIMP-1 and GFAP.
Kamel AA, Nassar AY, Meligy FY, Omar YA, Nassar GAY, Ezzat GM. Kamel AA, et al. Cell Biochem Funct. 2024 Mar;42(2):e3958. doi: 10.1002/cbf.3958. Cell Biochem Funct. 2024. PMID: 38396357
Iron accumulation in the brain causes oxidative stress, blood-brain barrier (BBB) breakdown, and neurodegeneration. ...At the start, all rats received 150 mg/kg/day of oral NAC for a week. The 40 animals were then randomly divided into fo
Iron accumulation in the brain causes oxidative stress, blood-brain barrier (BBB) breakdown, and neurodegener
A new metal ion chelator attenuates human tau accumulation-induced neurodegeneration and memory deficits in mice.
Zuo Y, Liu HT, Lin LB, Yue RZ, Liu HH, Wang HW, Wang L, Hou RL, Liu WZ, Li CZ, Wang JZ, Li P, Yin YL. Zuo Y, et al. Exp Neurol. 2024 Mar;373:114657. doi: 10.1016/j.expneurol.2023.114657. Epub 2023 Dec 22. Exp Neurol. 2024. PMID: 38141802
To explore whether abnormally phosphorylated Tau causes metal ion deposition, we overexpressed human full-length Tau (hTau) in the hippocampal CA3 area of mice and primary cultured hippocampal neurons (CPHN) and found that Tau accumulation induced iron deposition an …
To explore whether abnormally phosphorylated Tau causes metal ion deposition, we overexpressed human full-length Tau (hTau) in the hippocamp …
Neuroprotective responses of quercetin in regulation of biochemical, structural, and neurobehavioral effects in 28-day oral exposure of iron in rats.
Urati A, Angati A, Singh Gautam A, Dey M, Pandey SK, Singh RK. Urati A, et al. Toxicol Mech Methods. 2024 Jan;34(1):57-71. doi: 10.1080/15376516.2023.2256840. Epub 2023 Sep 12. Toxicol Mech Methods. 2024. PMID: 37680063
BACKGROUND: Iron is one of the essential metals that functions as a cofactor in various biological cascades in the brain. However, excessive iron accumulation in the brain may lead to neurodegeneration and may show toxic effects. ...
BACKGROUND: Iron is one of the essential metals that functions as a cofactor in various biological cascades in the brain. Howe …
17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy.
Tian Y, Xie Y, Guo Z, Feng P, You Y, Yu Q. Tian Y, et al. Redox Biol. 2023 Jun;62:102708. doi: 10.1016/j.redox.2023.102708. Epub 2023 Apr 23. Redox Biol. 2023. PMID: 37116254 Free PMC article.
Ovariectomy (OVX) conducted before the onset of natural menopause is considered to bringing forward and accelerate the process of ageing-associated neurodegeneration. However, the mechanisms underlying memory decline and other cognitive dysfunctions following OVX are uncle …
Ovariectomy (OVX) conducted before the onset of natural menopause is considered to bringing forward and accelerate the process of ageing-ass …
Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels.
Talaverón-Rey M, Álvarez-Córdoba M, Villalón-García I, Povea-Cabello S, Suárez-Rivero JM, Gómez-Fernández D, Romero-González A, Suárez-Carrillo A, Munuera-Cabeza M, Cilleros-Holgado P, Reche-López D, Piñero-Pérez R, Sánchez-Alcázar JA. Talaverón-Rey M, et al. Orphanet J Rare Dis. 2023 Apr 12;18(1):80. doi: 10.1186/s13023-023-02687-5. Orphanet J Rare Dis. 2023. PMID: 37046296 Free PMC article.
BACKGROUND: Neurodegeneration with brain iron accumulation (NBIA) disorders are a group of neurodegenerative diseases that have in common the accumulation of iron in the basal nuclei of the brain which are essential components of t …
BACKGROUND: Neurodegeneration with brain iron accumulation (NBIA) disorders are a group of neurodegenerative dis …
Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson's disease.
Alvarez Jerez P, Alcantud JL, de Los Reyes-Ramírez L, Moore A, Ruz C, Vives Montero F, Rodriguez-Losada N, Saini P, Gan-Or Z, Alvarado CX, Makarious MB, Billingsley KJ, Blauwendraat C, Noyce AJ, Singleton AB, Duran R, Bandres-Ciga S. Alvarez Jerez P, et al. NPJ Parkinsons Dis. 2023 Apr 6;9(1):54. doi: 10.1038/s41531-023-00496-y. NPJ Parkinsons Dis. 2023. PMID: 37024536 Free PMC article.
Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characterized by abnormal iron accumulation in the brain. In Parkinson's Disease (PD), iron accumulation is a car
Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characte
A novel C19ORF12 mutation in two MPAN sisters treated with deferiprone.
Chen S, Lai X, Fu J, Yang J, Zhao B, Shang H, Huang R, Chen X. Chen S, et al. BMC Neurol. 2023 Mar 31;23(1):134. doi: 10.1186/s12883-023-03172-z. BMC Neurol. 2023. PMID: 37004026 Free PMC article.
MPAN is characterized by pathological iron accumulation in the brain and fewer than 100 cases of MPAN have been described. ...The diagnosis of MPAN were established based on typical clinical manifestations, physical examination, brain magnetic r …
MPAN is characterized by pathological iron accumulation in the brain and fewer than 100 cases of MPAN have been describ …
142 results