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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 3
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1989 7
1990 7
1991 8
1992 5
1993 5
1994 3
1995 9
1996 5
1997 6
1998 8
1999 7
2000 7
2001 4
2002 3
2003 8
2004 8
2005 6
2006 17
2007 9
2008 20
2009 11
2010 15
2011 16
2012 27
2013 20
2014 30
2015 40
2016 48
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2019 63
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2021 55
2022 49
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2025 67
2026 21

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767 results

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Page 1
Management of neurofibromatosis type 1-associated plexiform neurofibromas.
Fisher MJ, Blakeley JO, Weiss BD, Dombi E, Ahlawat S, Akshintala S, Belzberg AJ, Bornhorst M, Bredella MA, Cai W, Ferner RE, Gross AM, Harris GJ, Listernick R, Ly I, Martin S, Mautner VF, Salamon JM, Salerno KE, Spinner RJ, Staedtke V, Ullrich NJ, Upadhyaya M, Wolters PL, Yohay K, Widemann BC. Fisher MJ, et al. Neuro Oncol. 2022 Nov 2;24(11):1827-1844. doi: 10.1093/neuonc/noac146. Neuro Oncol. 2022. PMID: 35657359 Free PMC article. Review.
Plexiform Neurofibromas (PN) are a common manifestation of the genetic disorder neurofibromatosis type 1 (NF1). These benign nerve sheath tumors often cause significant morbidity, with treatment options limited historically to surgery. ...
Plexiform Neurofibromas (PN) are a common manifestation of the genetic disorder neurofibromatosis type 1 (NF1). These benign nerve sh …
Vestibular Schwannomas.
Carlson ML, Link MJ. Carlson ML, et al. N Engl J Med. 2021 Apr 8;384(14):1335-1348. doi: 10.1056/NEJMra2020394. N Engl J Med. 2021. PMID: 33826821 Review. No abstract available.
ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma.
Moertel CL, Hirbe AC, Shuhaiber HH, Bielamowicz K, Sidhu A, Viskochil D, Weber MD, Lokku A, Smith LM, Foreman NK, Hajjar FM, McNall-Knapp RY, Weintraub L, Antony R, Franson AT, Meade J, Schiff D, Walbert T, Ambady P, Bota DA, Campen CJ, Kaur G, Klesse LJ, Maraka S, Moots PL, Nevel K, Bornhorst M, Aguilar-Bonilla A, Chagnon S, Dalvi N, Gupta P, Khatib Z, Metrock LK, Nghiemphu PL, Roberts RD, Robison NJ, Sadighi Z, Stapleton S, Babovic-Vuksanovic D, Gershon TR; ReNeu Trial Investigators; ReNeu Study Investigators. Moertel CL, et al. J Clin Oncol. 2025 Feb 20;43(6):716-729. doi: 10.1200/JCO.24.01034. Epub 2024 Nov 8. J Clin Oncol. 2025. PMID: 39514826 Free PMC article. Clinical Trial.
Both cohorts reported significant and clinically meaningful improvement in patient- or parent proxy-reported outcome measures of worst tumor pain severity, pain interference, and health-related quality of life (HRQOL) that began early and were sustained during treatment. . …
Both cohorts reported significant and clinically meaningful improvement in patient- or parent proxy-reported outcome measures of worst tu …
Peripheral nerve tumors.
Giannini C, Righi A. Giannini C, et al. Handb Clin Neurol. 2024;201:251-271. doi: 10.1016/B978-0-323-90108-6.00016-8. Handb Clin Neurol. 2024. PMID: 38697744 Review.
The chapter is focused on the neoplastic peripheral nerve lesions, which primarily involve "cranial and paraspinal nerves," as outlined in the CNS volume (WHO_Classification_of_Tumours_Editorial_Board, 2021). These include classic peripheral nerve shea …
The chapter is focused on the neoplastic peripheral nerve lesions, which primarily involve "cranial and paraspinal nerves," as …
Early Detection of Malignant and Premalignant Peripheral Nerve Tumors Using Cell-Free DNA Fragmentomics.
Sundby RT, Szymanski JJ, Pan AC, Jones PA, Mahmood SZ, Reid OH, Srihari D, Armstrong AE, Chamberlain S, Burgic S, Weekley K, Murray B, Patel S, Qaium F, Lucas AN, Fagan M, Dufek A, Meyer CF, Collins NB, Pratilas CA, Dombi E, Gross AM, Kim A, Chrisinger JSA, Dehner CA, Widemann BC, Hirbe AC, Chaudhuri AA, Shern JF. Sundby RT, et al. Clin Cancer Res. 2024 Oct 1;30(19):4363-4376. doi: 10.1158/1078-0432.CCR-24-0797. Clin Cancer Res. 2024. PMID: 39093127 Free PMC article.
PURPOSE: Early detection of neurofibromatosis type 1 (NF1)-associated peripheral nerve sheath tumors (PNST) informs clinical decision-making, enabling early definitive treatment and potentially averting deadly outcomes. ...
PURPOSE: Early detection of neurofibromatosis type 1 (NF1)-associated peripheral nerve sheath tumors (PNST) informs clinical d …
What is new in intraneural perineurioma?
Lenartowicz KA, Smith BW, Jack MM, Wilson TJ, Klein CJ, Amrami KK, Spinner RJ. Lenartowicz KA, et al. Acta Neurochir (Wien). 2023 Nov;165(11):3539-3547. doi: 10.1007/s00701-023-05765-6. Epub 2023 Sep 9. Acta Neurochir (Wien). 2023. PMID: 37684428 Review.
Since the initial description of intraneural (IN) perineurioma in 1964, advances in the understanding of the clinical presentation, diagnostic imaging, pathologic features, and genetic underpinnings have changed how this pathology is managed. IN perineuriomas are rare, benign …
Since the initial description of intraneural (IN) perineurioma in 1964, advances in the understanding of the clinical presentation, diagnost …
Complication avoidance.
Spinner RJ. Spinner RJ. Neurosurg Clin N Am. 2004 Apr;15(2):193-202, vii. doi: 10.1016/j.nec.2004.01.003. Neurosurg Clin N Am. 2004. PMID: 15177318 Review.
Complications are relatively common in the evaluation and treatment of patients with peripheral nerve tumors. The complications are frequently avoidable. Physicians and surgeons managing patients with these lesions must possess sufficient knowledge about peripher …
Complications are relatively common in the evaluation and treatment of patients with peripheral nerve tumors. The complication …
Update on Peripheral Nerve Sheath Tumors.
Martinez AP, Fritchie KJ. Martinez AP, et al. Surg Pathol Clin. 2019 Mar;12(1):1-19. doi: 10.1016/j.path.2018.10.001. Epub 2018 Dec 17. Surg Pathol Clin. 2019. PMID: 30709438 Review.
Additional studies have evaluated the utility and limitations of histone H3K27 trimethylation in diagnosis of high-grade and low-grade malignant peripheral nerve sheath tumors. New terminology regarding nerve sheath tumors in neurofibromatosis type 1 patients …
Additional studies have evaluated the utility and limitations of histone H3K27 trimethylation in diagnosis of high-grade and low-grade malig …
Malignant Melanotic Nerve Sheath Tumor.
Benson JC, Marais MD, Flanigan PM, Bydon M, Giannini C, Spinner RJ, Folpe AL. Benson JC, et al. AJNR Am J Neuroradiol. 2022 Dec;43(12):1696-1699. doi: 10.3174/ajnr.A7691. Epub 2022 Oct 27. AJNR Am J Neuroradiol. 2022. PMID: 36302602 Free article.
Malignant melanotic nerve sheath tumors are uncommon pigmented tumors of Schwann cell origin, most often found along the spinal nerves. ...In this radiology-pathology review, we will highlight the imaging appearance, histologic features, surgical resection, and subsequent …
Malignant melanotic nerve sheath tumors are uncommon pigmented tumors of Schwann cell origin, most often found along the spinal nerve …
Synovial sarcoma of nerve.
Scheithauer BW, Amrami KK, Folpe AL, Silva AI, Edgar MA, Woodruff JM, Levi AD, Spinner RJ. Scheithauer BW, et al. Hum Pathol. 2011 Apr;42(4):568-77. doi: 10.1016/j.humpath.2010.08.019. Epub 2011 Feb 4. Hum Pathol. 2011. PMID: 21295819 Review.
Tumors of peripheral nerve are largely neuroectodermal in nature and derived from 2 elements of nerve, Schwann or perineurial cells. ...Of malignant peripheral nerve neoplasms, the vast majority are primary peripheral nerve …
Tumors of peripheral nerve are largely neuroectodermal in nature and derived from 2 elements of nerve, Schwann or perin …
767 results