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1966 1
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140 results

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Page 1
Everolimus and sirolimus in the treatment of cardiac rhabdomyomas in neonates.
Hurtado-Sierra D, Ramos Garzón JX, Romero-Guevara SL, Serrano-García AY, Rojas LZ. Hurtado-Sierra D, et al. Pediatr Res. 2025 Apr 26. doi: 10.1038/s41390-025-04043-8. Online ahead of print. Pediatr Res. 2025. PMID: 40287604
The average daily doses were 1.03 mg/m2/day for everolimus and 1.37 mg/m2/day for sirolimus. Randomized controlled clinical trials are necessary to confirm these findings and establish optimal treatment protocols. IMPACT: Currently, there are no results from rand …
The average daily doses were 1.03 mg/m2/day for everolimus and 1.37 mg/m2/day for sirolimus. Randomized controlled clinical tr …
Characteristics and Outcomes of Fetal Cardiac Rhabdomyoma With or Without mTOR Inhibitors, a Systematic Review and Meta-Analysis.
Mustafa HJ, Javinani A, Morning ML, D'Antonio F, Pagani G, Puranik PM, Khalil A, Shamshirsaz AA. Mustafa HJ, et al. Prenat Diagn. 2024 Sep;44(10):1251-1267. doi: 10.1002/pd.6640. Epub 2024 Aug 20. Prenat Diagn. 2024. PMID: 39164800
OBJECTIVES: To investigate the characteristics and outcomes of fetal cardiac rhabdomyoma with or without prenatal use of mammalian target of rapamycin inhibitor (mTORi). ...CONCLUSIONS: We report on the natural history of prenatal cardiac rhabdomyoma, including char …
OBJECTIVES: To investigate the characteristics and outcomes of fetal cardiac rhabdomyoma with or without prenatal use of mammalian ta …
Cardiac rhabdomyoma: an uncommon culprit in sudden infant death.
Mecklenburg KL, Mitchell EK, Prahlow JA. Mecklenburg KL, et al. Forensic Sci Med Pathol. 2024 Sep;20(3):977-982. doi: 10.1007/s12024-023-00737-9. Epub 2024 Jul 4. Forensic Sci Med Pathol. 2024. PMID: 38963610 Free PMC article.
Autopsy is a crucial diagnostic step in these cases, as both gross and microscopic examination of the heart may uncover occult cardiac tumors. Rhabdomyomas are the most common cardiac tumors in childhood and may result in arrythmia and sudden death. ...Had a single rand …
Autopsy is a crucial diagnostic step in these cases, as both gross and microscopic examination of the heart may uncover occult cardiac tumor …
Neonatal Cardiac Rhabdomyoma: A Single-Center Experience.
Kaya B, Akduman H, Dilli D, Sayıcı İU, Kunt S, Doğangönül M, Şahin G, Aksoy ÖN, Uçan B, Zenciroğlu A. Kaya B, et al. Z Geburtshilfe Neonatol. 2024 Dec;228(6):520-527. doi: 10.1055/a-2325-5490. Epub 2024 Jun 13. Z Geburtshilfe Neonatol. 2024. PMID: 38871000
This study aims to present our single-center experience regarding clinical observations, diagnostic approaches, and treatment modalities for cardiac rhabdomyoma identified during the neonatal period. ...Timely diagnosis, appropriate clinical management, and m …
This study aims to present our single-center experience regarding clinical observations, diagnostic approaches, and treatment modalit …
Early Subclinical Status Epilepticus May Contribute to Developmental Delays in Infants With Tuberous Sclerosis Complex.
Melendez-Zaidi AE, Pence KL, Coorg R. Melendez-Zaidi AE, et al. Pediatr Neurol. 2024 Aug;157:39-41. doi: 10.1016/j.pediatrneurol.2024.05.010. Epub 2024 May 17. Pediatr Neurol. 2024. PMID: 38865948
We present a case of a newborn with a prenatally discovered cardiac rhabdomyoma leading to early genetic diagnosis of tuberous sclerosis complex (TSC). This early diagnosis prompted a presymptomatic electroencephalography (EEG) that revealed subclinical seizures meeting th …
We present a case of a newborn with a prenatally discovered cardiac rhabdomyoma leading to early genetic diagnosis of tuberous sclero …
MicroRNAs and angiosarcoma: are there promising reports?
Modarresi Chahardehi A, Afrooghe A, Emtiazi N, Rafiei S, Rezaei NJ, Dahmardeh S, Farz F, Naderi Z, Arefnezhad R, Motedayyen H. Modarresi Chahardehi A, et al. Front Oncol. 2024 May 17;14:1385632. doi: 10.3389/fonc.2024.1385632. eCollection 2024. Front Oncol. 2024. PMID: 38826780 Free PMC article. Review.
Notably, angiosarcoma, along with various other cardiovascular tumors such as lipomas, rhabdomyomas, hemangiomas, and myxomas, has shown variations in the expression of specific miRNA subtypes. ...These insights can serve as the groundwork for designing randomized c …
Notably, angiosarcoma, along with various other cardiovascular tumors such as lipomas, rhabdomyomas, hemangiomas, and myxomas, has sh …
Multiple recurrent supraventricular tachycardia in infantile tuberous sclerosis complex: management requiring triple-drug therapy.
Jacquemyn X, Kutty S, Cohen MI, Mehta KK. Jacquemyn X, et al. Cardiol Young. 2024 Jul;34(7):1600-1605. doi: 10.1017/S1047951124000325. Epub 2024 May 24. Cardiol Young. 2024. PMID: 38785339
Multimodality imaging and genetic testing confirmed a diagnosis of tuberous sclerosis complex with multiple cardiac rhabdomyomas. At 13 days of age, the patient was readmitted, exhibiting recurrent supraventricular tachycardia non-responsive to first-line treatment. ...
Multimodality imaging and genetic testing confirmed a diagnosis of tuberous sclerosis complex with multiple cardiac rhabdomyomas. At …
Cardiac Rhabdomyomas Presenting with Critical Cardiac Obstruction in Neonates and Infants: Treatment Strategies and Outcome, A Single-Center Experience.
Ng LY, McGuinness J, Prendiville T, Franklin O, Walsh M, Kenny D, Nolke L, McMahon CJ. Ng LY, et al. Pediatr Cardiol. 2024 Jun;45(5):1132-1141. doi: 10.1007/s00246-024-03420-0. Epub 2024 Mar 13. Pediatr Cardiol. 2024. PMID: 38480570 Free PMC article.
Cardiac rhabdomyomas are the most common benign pediatric heart tumor in infancy, which are commonly associated with tuberous sclerosis complex (TSC). ...We present the outcomes of neonates and an infant who received treatment for symptomatic rhabdomyomas at a terti …
Cardiac rhabdomyomas are the most common benign pediatric heart tumor in infancy, which are commonly associated with tuberous scleros …
140 results