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Page 1
ACG Clinical Guideline: Alcohol-Associated Liver Disease.
Jophlin LL, Singal AK, Bataller R, Wong RJ, Sauer BG, Terrault NA, Shah VH. Jophlin LL, et al. Am J Gastroenterol. 2024 Jan 1;119(1):30-54. doi: 10.14309/ajg.0000000000002572. Epub 2023 Sep 1. Am J Gastroenterol. 2024. PMID: 38174913 Free PMC article.
Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic disease and frequent indication for liver transplantation worldwide. With harmful alcohol use as the primary risk factor, increasing alcohol use over the past decade has resul …
Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic disease and frequent indication for liver transpl …
ACG Clinical Guideline: Alcoholic Liver Disease.
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH. Singal AK, et al. Am J Gastroenterol. 2018 Feb;113(2):175-194. doi: 10.1038/ajg.2017.469. Epub 2018 Jan 16. Am J Gastroenterol. 2018. PMID: 29336434 Free PMC article.
Diagnosis of ALD requires documentation of chronic heavy alcohol use and exclusion of other causes of liver disease. Prolonged abstinence is the most effective strategy to prevent disease progression. ...Corticosteroids provide short-term survival benefit in about half of …
Diagnosis of ALD requires documentation of chronic heavy alcohol use and exclusion of other causes of liver disease. Prolonged abstin …
Acute-on-chronic liver failure in cirrhosis.
Arroyo V, Moreau R, Kamath PS, Jalan R, Ginès P, Nevens F, Fernández J, To U, García-Tsao G, Schnabl B. Arroyo V, et al. Nat Rev Dis Primers. 2016 Jun 9;2:16041. doi: 10.1038/nrdp.2016.41. Nat Rev Dis Primers. 2016. PMID: 27277335 Free article. Review.
ACLF frequently occurs in a closed temporal relationship to a precipitating event, such as bacterial infection or acute alcoholic, drug-induced or viral hepatitis. However, no precipitating event can be identified in approximately 40% of patients. ...
ACLF frequently occurs in a closed temporal relationship to a precipitating event, such as bacterial infection or acute alcoholic, drug …
Medical student distress: causes, consequences, and proposed solutions.
Dyrbye LN, Thomas MR, Shanafelt TD. Dyrbye LN, et al. Mayo Clin Proc. 2005 Dec;80(12):1613-22. doi: 10.4065/80.12.1613. Mayo Clin Proc. 2005. PMID: 16342655
On a personal level, this distress can contribute to substance abuse, broken relationships, suicide, and attrition from the profession. On a professional level, studies suggest that student distress contributes to cynicism and subsequently may affect students' care …
On a personal level, this distress can contribute to substance abuse, broken relationships, suicide, and attrition from the pr …
GLP-1 agonists: a game changer in pain treatment and addiction.
Bade S, Hurdle MFB, Bade S, Encalada S, Kanahan-Osman S, Gupta S. Bade S, et al. Pain Manag. 2025 Oct;15(10):753-765. doi: 10.1080/17581869.2025.2536998. Epub 2025 Jul 28. Pain Manag. 2025. PMID: 40726115 Free PMC article. Review.
These drugs may also help reduce cravings and prevent relapse in people recovering from substance use disorders. Although this new role for GLP-1RAs is exciting, more research is needed. ...Larger and longer-term studies will help confirm how effective and safe thes …
These drugs may also help reduce cravings and prevent relapse in people recovering from substance use disorders. Although this …
Management of alcohol use disorder: a gastroenterology and hepatology-focused perspective.
Díaz LA, König D, Weber S, Ayares G, Fuentealba JM, Vázquez V, Bataller R, Kamath PS, Winder GS, Leggio L, Arab JP. Díaz LA, et al. Lancet Gastroenterol Hepatol. 2025 May;10(5):475-490. doi: 10.1016/S2468-1253(24)00380-7. Epub 2025 Feb 13. Lancet Gastroenterol Hepatol. 2025. PMID: 39956128 Review.
Despite its substantial effects, most clinicians do not adequately assess alcohol intake in clinical practice, and there are several barriers to providing integrated management to patients with alcohol use disorder. Standardised questionnaires, such as the Alcoho …
Despite its substantial effects, most clinicians do not adequately assess alcohol intake in clinical practice, and there are several …
Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department.
Borgundvaag B, Bellolio F, Miles I, Schwarz ES, Sharif S, Su MK, Baumgartner K, Liss DB, Sheikh H, Vogel J, Austin EB, Upadhye S, Klaiman M, Vellend R, Munkley A, Carpenter CR. Borgundvaag B, et al. Acad Emerg Med. 2024 May;31(5):425-455. doi: 10.1111/acem.14911. Acad Emerg Med. 2024. PMID: 38747203
The fourth Society for Academic Emergency Medicine (SAEM) Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4) is on the topic of the emergency department (ED) management of nonopioid use disorders and focuses on alcohol withdrawal …
The fourth Society for Academic Emergency Medicine (SAEM) Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE- …
Clinical trial design, biomarkers and end points in metabolic and alcohol-related liver disease.
Diaz LA, Thiele M, Louvet A, Lee BP, Ajmera V, Tavaglione F, Hsu CL, Huang DQ, Pose E, Bataller R, McClain C, Mellinger J, Tincopa M, Mitchell MC, Ratziu V, Rinella ME, Sarin SK, Shah VH, Szabo G, Wong VW, Bansal MB, Leggio L, Kamath PS, Krag A, Sanyal AJ, Arrese M, Arab JP, Anstee QM, Mathurin P, Loomba R. Diaz LA, et al. Nat Rev Gastroenterol Hepatol. 2025 Dec;22(12):866-884. doi: 10.1038/s41575-025-01120-5. Epub 2025 Sep 26. Nat Rev Gastroenterol Hepatol. 2025. PMID: 41006824 Review.
Metabolic and alcohol-related liver disease (MetALD) is a newly defined entity within the spectrum of steatotic liver disease, characterized by the interplay of cardiometabolic risk factors and alcohol consumption. ...These advances will ultimately accelerate dru …
Metabolic and alcohol-related liver disease (MetALD) is a newly defined entity within the spectrum of steatotic liver disease, charac …
Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000-2021.
Danpanichkul P, Díaz LA, Suparan K, Tothanarungroj P, Sirimangklanurak S, Auttapracha T, Blaney HL, Sukphutanan B, Pang Y, Kongarin S, Idalsoaga F, Fuentes-López E, Leggio L, Noureddin M, White TM, Louvet A, Mathurin P, Loomba R, Kamath PS, Rehm J, Lazarus JV, Wijarnpreecha K, Arab JP. Danpanichkul P, et al. Clin Mol Hepatol. 2025 Apr;31(2):525-547. doi: 10.3350/cmh.2024.0835. Epub 2025 Jan 9. Clin Mol Hepatol. 2025. PMID: 39788109 Free PMC article.
BACKGROUND/AIMS: Alcohol represents a leading burden of disease worldwide, including alcohol use disorder (AUD) and alcohol-related liver disease (ALD). ...RESULTS: In 2021, there were 111.12 million cases of AUD, 3.02 million cases of ALD, and 132,030 cases …
BACKGROUND/AIMS: Alcohol represents a leading burden of disease worldwide, including alcohol use disorder (AUD) and alcohol …
1,326 results