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Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: A consensus report from the International League Against Epilepsy Neuroimaging Task Force.
Bernasconi A, Cendes F, Theodore WH, Gill RS, Koepp MJ, Hogan RE, Jackson GD, Federico P, Labate A, Vaudano AE, Blümcke I, Ryvlin P, Bernasconi N. Bernasconi A, et al. Among authors: bernasconi n. Epilepsia. 2019 Jun;60(6):1054-1068. doi: 10.1111/epi.15612. Epub 2019 May 28. Epilepsia. 2019. PMID: 31135062 Review.
(2) What are the minimum requirements for an MRI epilepsy protocol? (3) How should magnetic resonance (MR) images be evaluated? ...The Neuroimaging Task Force also endorses the use of computer-aided image postprocessing methods to provide an objective account of an individ …
(2) What are the minimum requirements for an MRI epilepsy protocol? (3) How should magnetic resonance (MR) images be evaluated? ...Th …
Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression.
Larivière S, Royer J, Rodríguez-Cruces R, Paquola C, Caligiuri ME, Gambardella A, Concha L, Keller SS, Cendes F, Yasuda CL, Bonilha L, Gleichgerrcht E, Focke NK, Domin M, von Podewills F, Langner S, Rummel C, Wiest R, Martin P, Kotikalapudi R, O'Brien TJ, Sinclair B, Vivash L, Desmond PM, Lui E, Vaudano AE, Meletti S, Tondelli M, Alhusaini S, Doherty CP, Cavalleri GL, Delanty N, Kälviäinen R, Jackson GD, Kowalczyk M, Mascalchi M, Semmelroch M, Thomas RH, Soltanian-Zadeh H, Davoodi-Bojd E, Zhang J, Winston GP, Griffin A, Singh A, Tiwari VK, Kreilkamp BAK, Lenge M, Guerrini R, Hamandi K, Foley S, Rüber T, Weber B, Depondt C, Absil J, Carr SJA, Abela E, Richardson MP, Devinsky O, Severino M, Striano P, Tortora D, Kaestner E, Hatton SN, Vos SB, Caciagli L, Duncan JS, Whelan CD, Thompson PM, Sisodiya SM, Bernasconi A, Labate A, McDonald CR, Bernasconi N, Bernhardt BC. Larivière S, et al. Among authors: bernasconi n, bernasconi a. Nat Commun. 2022 Jul 27;13(1):4320. doi: 10.1038/s41467-022-31730-5. Nat Commun. 2022. PMID: 35896547 Free PMC article.
This multisite ENIGMA-Epilepsy study examined whole-brain structural covariance networks in patients with epilepsy and related findings to postmortem epilepsy risk gene expression patterns. Brain network analysis included 578 adults with temporal lobe epil …
This multisite ENIGMA-Epilepsy study examined whole-brain structural covariance networks in patients with epilepsy and related …
Diagnostic methods and treatment options for focal cortical dysplasia.
Guerrini R, Duchowny M, Jayakar P, Krsek P, Kahane P, Tassi L, Melani F, Polster T, Andre VM, Cepeda C, Krueger DA, Cross JH, Spreafico R, Cosottini M, Gotman J, Chassoux F, Ryvlin P, Bartolomei F, Bernasconi A, Stefan H, Miller I, Devaux B, Najm I, Giordano F, Vonck K, Barba C, Blumcke I. Guerrini R, et al. Among authors: bernasconi a. Epilepsia. 2015 Nov;56(11):1669-86. doi: 10.1111/epi.13200. Epub 2015 Oct 5. Epilepsia. 2015. PMID: 26434565 Free article. Review.
Our inability to adequately treat many patients with refractory epilepsy caused by focal cortical dysplasia (FCD), surgical inaccessibility and failures are significant clinical drawbacks. ...Pathogenic mutations recently described in mammalian target of rapamycin (mTOR) g …
Our inability to adequately treat many patients with refractory epilepsy caused by focal cortical dysplasia (FCD), surgical inaccessi …
Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy.
Park BY, Larivière S, Rodríguez-Cruces R, Royer J, Tavakol S, Wang Y, Caciagli L, Caligiuri ME, Gambardella A, Concha L, Keller SS, Cendes F, Alvim MKM, Yasuda C, Bonilha L, Gleichgerrcht E, Focke NK, Kreilkamp BAK, Domin M, von Podewils F, Langner S, Rummel C, Rebsamen M, Wiest R, Martin P, Kotikalapudi R, Bender B, O'Brien TJ, Law M, Sinclair B, Vivash L, Kwan P, Desmond PM, Malpas CB, Lui E, Alhusaini S, Doherty CP, Cavalleri GL, Delanty N, Kälviäinen R, Jackson GD, Kowalczyk M, Mascalchi M, Semmelroch M, Thomas RH, Soltanian-Zadeh H, Davoodi-Bojd E, Zhang J, Lenge M, Guerrini R, Bartolini E, Hamandi K, Foley S, Weber B, Depondt C, Absil J, Carr SJA, Abela E, Richardson MP, Devinsky O, Severino M, Striano P, Parodi C, Tortora D, Hatton SN, Vos SB, Duncan JS, Galovic M, Whelan CD, Bargalló N, Pariente J, Conde-Blanco E, Vaudano AE, Tondelli M, Meletti S, Kong XZ, Francks C, Fisher SE, Caldairou B, Ryten M, Labate A, Sisodiya SM, Thompson PM, McDonald CR, Bernasconi A, Bernasconi N, Bernhardt BC. Park BY, et al. Among authors: bernasconi n, bernasconi a. Brain. 2022 May 24;145(4):1285-1298. doi: 10.1093/brain/awab417. Brain. 2022. PMID: 35333312 Free PMC article.
Temporal lobe epilepsy, a common drug-resistant epilepsy in adults, is primarily a limbic network disorder associated with predominant unilateral hippocampal pathology. ...These findings refine our notion of the neuropathology of temporal lobe epilepsy and ma …
Temporal lobe epilepsy, a common drug-resistant epilepsy in adults, is primarily a limbic network disorder associated with pre …
International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods.
Blümcke I, Thom M, Aronica E, Armstrong DD, Bartolomei F, Bernasconi A, Bernasconi N, Bien CG, Cendes F, Coras R, Cross JH, Jacques TS, Kahane P, Mathern GW, Miyata H, Moshé SL, Oz B, Özkara Ç, Perucca E, Sisodiya S, Wiebe S, Spreafico R. Blümcke I, et al. Among authors: bernasconi n, bernasconi a. Epilepsia. 2013 Jul;54(7):1315-29. doi: 10.1111/epi.12220. Epub 2013 May 20. Epilepsia. 2013. PMID: 23692496 Free article.
Hippocampal sclerosis (HS) is the most frequent histopathology encountered in patients with drug-resistant temporal lobe epilepsy (TLE). Over the past decades, various attempts have been made to classify specific patterns of hippocampal neuronal cell loss and correlate sub …
Hippocampal sclerosis (HS) is the most frequent histopathology encountered in patients with drug-resistant temporal lobe epilepsy (TL …
Functional Networks in Epilepsy Presurgical Evaluation.
Foit NA, Bernasconi A, Bernasconi N. Foit NA, et al. Among authors: bernasconi n, bernasconi a. Neurosurg Clin N Am. 2020 Jul;31(3):395-405. doi: 10.1016/j.nec.2020.03.004. Epub 2020 Apr 23. Neurosurg Clin N Am. 2020. PMID: 32475488 Review.
Continuing advancements in neuroimaging methodology allow for increasingly detailed in vivo characterization of structural and functional brain networks, leading to the recognition of epilepsy as a disorder of large-scale networks. In surgical candidates, analysis of funct …
Continuing advancements in neuroimaging methodology allow for increasingly detailed in vivo characterization of structural and functional br …
Connectome biomarkers of drug-resistant epilepsy.
Larivière S, Bernasconi A, Bernasconi N, Bernhardt BC. Larivière S, et al. Among authors: bernasconi n, bernasconi a. Epilepsia. 2021 Jan;62(1):6-24. doi: 10.1111/epi.16753. Epub 2020 Nov 25. Epilepsia. 2021. PMID: 33236784
Drug-resistant epilepsy (DRE) considerably affects patient health, cognition, and well-being, and disproportionally contributes to the overall burden of epilepsy. The most common DRE syndromes are temporal lobe epilepsy related to mesiotemporal sclerosis and …
Drug-resistant epilepsy (DRE) considerably affects patient health, cognition, and well-being, and disproportionally contributes to th …
Gustatory agnosia.
Small DM, Bernasconi N, Bernasconi A, Sziklas V, Jones-Gotman M. Small DM, et al. Among authors: bernasconi n, bernasconi a. Neurology. 2005 Jan 25;64(2):311-7. doi: 10.1212/01.WNL.0000149515.77718.35. Neurology. 2005. PMID: 15668430
METHODS: Preoperative and postoperative neuropsychological, neuroimaging, and chemosensory evaluations were performed in a 39-year-old woman undergoing surgical treatment for intractable epilepsy. RESULTS: Preoperative MRIs showed bilateral (right > left) atrophy in the …
METHODS: Preoperative and postoperative neuropsychological, neuroimaging, and chemosensory evaluations were performed in a 39-year-old woman …
Histological and MRI markers of white matter damage in focal epilepsy.
Deleo F, Thom M, Concha L, Bernasconi A, Bernhardt BC, Bernasconi N. Deleo F, et al. Among authors: bernasconi n, bernasconi a. Epilepsy Res. 2018 Feb;140:29-38. doi: 10.1016/j.eplepsyres.2017.11.010. Epub 2017 Nov 23. Epilepsy Res. 2018. PMID: 29227798 Review.
Growing evidence highlights the importance of white matter in the pathogenesis of focal epilepsy. Ex vivo and post-mortem studies show pathological changes in epileptic patients in white matter myelination, axonal integrity, and cellular composition. ...Focus is put on tem …
Growing evidence highlights the importance of white matter in the pathogenesis of focal epilepsy. Ex vivo and post-mortem studies sho …
The Role of MRI in the Treatment of Drug-Resistant Focal Epilepsy.
Bernasconi A, Bernasconi N. Bernasconi A, et al. Among authors: bernasconi n. Eur Neurol. 2022;85(5):333-341. doi: 10.1159/000525262. Epub 2022 Jun 15. Eur Neurol. 2022. PMID: 35705017 Free article. Review.
BACKGROUND: Epilepsy is a prevalent chronic condition affecting about 50 million people worldwide. A third of patients with focal epilepsy suffer from seizures unresponsive to medication. Uncontrolled seizures damage the brain, are associated with cognitive decline, …
BACKGROUND: Epilepsy is a prevalent chronic condition affecting about 50 million people worldwide. A third of patients with focal …
152 results