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174 results

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Page 1
Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: A consensus report from the International League Against Epilepsy Neuroimaging Task Force.
Bernasconi A, Cendes F, Theodore WH, Gill RS, Koepp MJ, Hogan RE, Jackson GD, Federico P, Labate A, Vaudano AE, Blümcke I, Ryvlin P, Bernasconi N. Bernasconi A, et al. Among authors: bernasconi n. Epilepsia. 2019 Jun;60(6):1054-1068. doi: 10.1111/epi.15612. Epub 2019 May 28. Epilepsia. 2019. PMID: 31135062 Review.
Structural magnetic resonance imaging (MRI) is of fundamental importance to the diagnosis and treatment of epilepsy, particularly when surgery is being considered. Despite previous recommendations and guidelines, practices for the use of MRI are variable worldwide and may …
Structural magnetic resonance imaging (MRI) is of fundamental importance to the diagnosis and treatment of epilepsy, particularly whe …
MRI-negative epilepsy: A systematic review and meta-analysis.
Gill RS, Deleo F, Bernhardt B, Wiebe S, Bernasconi N, Bernasconi A. Gill RS, et al. Among authors: bernasconi n, bernasconi a. Epilepsia. 2025 Dec;66(12):4939-4949. doi: 10.1111/epi.18616. Epub 2025 Aug 19. Epilepsia. 2025. PMID: 40827585 Free PMC article.
OBJECTIVE: Drug-resistant focal epilepsy is commonly dichotomized based on magnetic resonance imaging (MRI) lesion visibility into positive (MRI-pos) and negative (MRI-neg). ...Given a 39% gain in diagnostic yield, MRI post-processing should be performed systematically as …
OBJECTIVE: Drug-resistant focal epilepsy is commonly dichotomized based on magnetic resonance imaging (MRI) lesion visibility into po …
Connectome biomarkers of drug-resistant epilepsy.
Larivière S, Bernasconi A, Bernasconi N, Bernhardt BC. Larivière S, et al. Among authors: bernasconi n, bernasconi a. Epilepsia. 2021 Jan;62(1):6-24. doi: 10.1111/epi.16753. Epub 2020 Nov 25. Epilepsia. 2021. PMID: 33236784
Drug-resistant epilepsy (DRE) considerably affects patient health, cognition, and well-being, and disproportionally contributes to the overall burden of epilepsy. The most common DRE syndromes are temporal lobe epilepsy related to mesiotemporal sclerosis and …
Drug-resistant epilepsy (DRE) considerably affects patient health, cognition, and well-being, and disproportionally contributes to th …
Connectome reorganization associated with temporal lobe pathology and its surgical resection.
Larivière S, Park BY, Royer J, DeKraker J, Ngo A, Sahlas E, Chen J, Rodríguez-Cruces R, Weng Y, Frauscher B, Liu R, Wang Z, Shafiei G, Mišić B, Bernasconi A, Bernasconi N, Fox MD, Zhang Z, Bernhardt BC. Larivière S, et al. Among authors: bernasconi n, bernasconi a. Brain. 2024 Jul 5;147(7):2483-2495. doi: 10.1093/brain/awae141. Brain. 2024. PMID: 38701342 Free PMC article.
Resection of the temporal lobe is the most effective treatment to control seizures in pharmaco-resistant temporal lobe epilepsy (TLE), making this syndrome a powerful model to study lesional effects on network organization in young and middle-aged adults. ...
Resection of the temporal lobe is the most effective treatment to control seizures in pharmaco-resistant temporal lobe epilepsy (TLE) …
Functional Networks in Epilepsy Presurgical Evaluation.
Foit NA, Bernasconi A, Bernasconi N. Foit NA, et al. Among authors: bernasconi n, bernasconi a. Neurosurg Clin N Am. 2020 Jul;31(3):395-405. doi: 10.1016/j.nec.2020.03.004. Epub 2020 Apr 23. Neurosurg Clin N Am. 2020. PMID: 32475488 Review.
Continuing advancements in neuroimaging methodology allow for increasingly detailed in vivo characterization of structural and functional brain networks, leading to the recognition of epilepsy as a disorder of large-scale networks. In surgical candidates, analysis of funct …
Continuing advancements in neuroimaging methodology allow for increasingly detailed in vivo characterization of structural and functional br …
Brain Networks for Cortical Atrophy and Responsive Neurostimulation in Temporal Lobe Epilepsy.
Larivière S, Schaper FLWVJ, Royer J, Rodríguez-Cruces R, Xie K, DeKraker J, Ngo A, Sahlas E, Chen J, Tavakol S, Drew W, Morton-Dutton M, Warren AEL, Baratono SR, Rolston JD, Weng Y, Bernasconi A, Bernasconi N, Concha L, Zhang Z, Frauscher B, Bernhardt BC, Fox MD. Larivière S, et al. Among authors: bernasconi n, bernasconi a. JAMA Neurol. 2024 Sep 30;81(11):1199-209. doi: 10.1001/jamaneurol.2024.2952. Online ahead of print. JAMA Neurol. 2024. PMID: 39348148 Free PMC article.
IMPORTANCE: Drug-resistant temporal lobe epilepsy (TLE) has been associated with hippocampal pathology. Most surgical treatment strategies, including resection and responsive neurostimulation (RNS), focus on this disease epicenter; however, imaging alterations distant from …
IMPORTANCE: Drug-resistant temporal lobe epilepsy (TLE) has been associated with hippocampal pathology. Most surgical treatment strat …
Associations between epilepsy-related polygenic risk and brain morphology in childhood.
Ngo A, Liu L, Larivière S, Kebets V, Fett S, Weber CF, Royer J, Yu E, Rodríguez-Cruces R, Zhang Z, Ooi LQR, Yeo BTT, Frauscher B, Paquola C, Caligiuri ME, Gambardella A, Concha L, Keller SS, Cendes F, Yasuda CL, Bonilha L, Gleichgerrcht E, Focke NKN, Kotikalapudi R, O'Brien TJ, Sinclair B, Vivash L, Desmond PM, Lui E, Vaudano AE, Meletti S, Kälviäinen R, Soltanian-Zadeh H, Winston GP, Tiwari VK, Kreilkamp BAK, Lenge M, Guerrini R, Hamandi K, Rüber T, Bauer T, Devinsky O, Striano P, Kaestner E, Hatton SN, Caciagli L, Kirschner M, Duncan JS, Thompson PM; ENIGMA Consortium Epilepsy Working Group; McDonald CR, Sisodiya SM, Bernasconi N, Bernasconi A, Gan-Or Z, Bernhardt BC. Ngo A, et al. Among authors: bernasconi n, bernasconi a. Brain. 2026 Feb 7;149(2):519-533. doi: 10.1093/brain/awaf259. Brain. 2026. PMID: 40811581
Extensive neuroimaging research in temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) has identified brain atrophy as a disease phenotype. ...These signatures offer a foundation for early risk stratification and personalized interventions targeting genetic profiles …
Extensive neuroimaging research in temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) has identified brain atrophy as a disea …
A WORLDWIDE ENIGMA STUDY ON EPILEPSY-RELATED GRAY AND WHITE MATTER COMPROMISE ACROSS THE ADULT LIFESPAN.
Chen J, Ngo A, Rodríguez-Cruces R, Royer J, Caligiuri ME, Gambardella A, Concha L, Keller SS, Cendes F, Yasuda CL, Alvim MKM, Bonilha L, Gleichgerrcht E, Focke NK, Kreilkamp B, Domin M, von Podewils F, Langner S, Rummel C, Wiest R, Martin P, Kotikalapudi R, Bender B, O'Brien TJ, Sinclair B, Vivash L, Kwan P, Desmond PM, Lui E, Duma GM, Bonanni P, Ballerini A, Vaudano AE, Meletti S, Tondelli M, Alhusaini S, Doherty CP, Cavalleri GL, Delanty N, Kälviäinen R, Jackson GD, Kowalczyk M, Mascalchi M, Semmelroch M, Thomas RH, Soltanian-Zadeh H, Davoodi-Bojd E, Zhang J, Lenge M, Guerrini R, Bartolini E, Hamandi K, Foley S, Rüber T, Bauer T, Weber B, Caldairou B, Depondt C, Absil J, Carr SJA, Abela E, Richardson MP, Devinsky O, Pardoe H, Severino M, Striano P, Tortora D, Kaestner E, Hatton SN, Arienzo D, Vos SB, Ryten M, Taylor PN, Duncan JS, Whelan CD, Galovic M, Winston GP, Thomopoulos SI, Thompson PM, Sisodiya SM, Labate A, McDonald CR, Caciagli L, Bernasconi N, Bernasconi A, Larivière S, Schrader D, Bernhardt BC. Chen J, et al. Among authors: bernasconi n, bernasconi a. bioRxiv [Preprint]. 2024 Mar 6:2024.03.02.583073. doi: 10.1101/2024.03.02.583073. bioRxiv. 2024. PMID: 38496668 Free PMC article. Preprint.
OBJECTIVES: Temporal lobe epilepsy (TLE) is commonly associated with mesiotemporal pathology and widespread alterations of grey and white matter structures. Evidence supports a progressive condition although the temporal evolution of TLE is poorly defined. This ENIGMA-E …
OBJECTIVES: Temporal lobe epilepsy (TLE) is commonly associated with mesiotemporal pathology and widespread alterations of grey and w …
Gustatory agnosia.
Small DM, Bernasconi N, Bernasconi A, Sziklas V, Jones-Gotman M. Small DM, et al. Among authors: bernasconi n, bernasconi a. Neurology. 2005 Jan 25;64(2):311-7. doi: 10.1212/01.WNL.0000149515.77718.35. Neurology. 2005. PMID: 15668430
METHODS: Preoperative and postoperative neuropsychological, neuroimaging, and chemosensory evaluations were performed in a 39-year-old woman undergoing surgical treatment for intractable epilepsy. RESULTS: Preoperative MRIs showed bilateral (right > left) atrophy in the …
METHODS: Preoperative and postoperative neuropsychological, neuroimaging, and chemosensory evaluations were performed in a 39-year-old woman …
Machine Learning in Neuroimaging of Epilepsy.
Lee HM, Gill RS, Bernasconi N, Bernasconi A. Lee HM, et al. Among authors: bernasconi n, bernasconi a. 2023 Jul 23. In: Colliot O, editor. Machine Learning for Brain Disorders [Internet]. New York, NY: Humana; 2023. Chapter 27. 2023 Jul 23. In: Colliot O, editor. Machine Learning for Brain Disorders [Internet]. New York, NY: Humana; 2023. Chapter 27. PMID: 37988515 Free Books & Documents. Review.
Epilepsy is a prevalent chronic condition affecting about 50 million people worldwide. A third of patients suffer from seizures unresponsive to medication. ...
Epilepsy is a prevalent chronic condition affecting about 50 million people worldwide. A third of patients suffer from seizures unres …
174 results