Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP.
Harkness RW, Toyama Y, Ripstein ZA, Zhao H, Sever AIM, Luan Q, Brady JP, Clark PL, Schuck P, Kay LE.
Harkness RW, et al. Among authors: clark pl.
Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2109732118. doi: 10.1073/pnas.2109732118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34362850
Free PMC article.
When bound to substrate proteins or lipid membranes, DegP has been shown to populate a variety of cage- or bowl-like oligomeric states that have increased proteolytic activity. Though a number of DegP's substrate-engaged structures have been robustly characterized, detaile …
When bound to substrate proteins or lipid membranes, DegP has been shown to populate a variety of cage- or bowl-like oligomeric states that …