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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 2
1996 1
1997 3
1998 14
1999 21
2000 23
2001 33
2002 32
2003 23
2004 31
2005 32
2006 34
2007 15
2008 20
2009 26
2010 24
2011 27
2012 19
2013 31
2014 25
2015 11
2016 19
2017 25
2018 16
2019 18
2020 23
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2025 18
2026 1

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70 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 5 years, Humans, English. Clear all
Page 1
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Pastras P, Aggeletopoulou I, Bali M, Triantos C. Pastras P, et al. Nutrients. 2026 Jan 6;18(2):183. doi: 10.3390/nu18020183. Nutrients. 2026. PMID: 41599795 Free PMC article. Review.
Other agents, including Aloe vera, flavonoids, St John's wort, and ginger, exhibit mixed or inconsistent results, reflecting heterogeneity in study designs and underlying mechanisms. ...
Other agents, including Aloe vera, flavonoids, St John's wort, and ginger, exhibit mixed or inconsistent results …
St. John's Wort for Depression: From Neurotransmitters to Membrane Plasticity.
Merk VM, Boonen G, Butterweck V. Merk VM, et al. Int J Mol Sci. 2025 Dec 10;26(24):11925. doi: 10.3390/ijms262411925. Int J Mol Sci. 2025. PMID: 41465351 Free PMC article. Review.
Depression is a multifactorial disorder shaped by genetic, psychosocial, and biological influences, with hypotheses ranging from monoamine deficiency and neuroplasticity deficits to inflammation and stress-induced dysregulation. St. John's wort (Hyp …
Depression is a multifactorial disorder shaped by genetic, psychosocial, and biological influences, with hypotheses ranging from monoamine d …
A Minireview on Nanosized Hypericin-Based Inducer of Immune Cell Death Under ROS-Based Therapies.
Xu C, Cai X, Du L. Xu C, et al. Int J Nanomedicine. 2025 Dec 9;20:14695-14705. doi: 10.2147/IJN.S566489. eCollection 2025. Int J Nanomedicine. 2025. PMID: 41393080 Free PMC article. Review.
Hypericin, a naturally occurring photosensitizer derived from the traditional Chinese herb Hypericum perforatum (St. John's wort), has been used medicinally for centuries, and is now recognized for its potent antimicrobial, antiviral, anti-infla …
Hypericin, a naturally occurring photosensitizer derived from the traditional Chinese herb Hypericum perforatum (St. John …
What over the counter (OTC) products have been evaluated for anxiety in adults aged 18-60? A scoping review.
Frost R, Uddin S, Mathew S, Thomas V, Salame A, Bhamra SK, Bazo-Alvarez JC, Bhanu C, Heinrich M, Walters K. Frost R, et al. J Ment Health. 2025 Dec;34(6):695-715. doi: 10.1080/09638237.2024.2408231. Epub 2024 Sep 30. J Ment Health. 2025. PMID: 39350596 Free article.
CONCLUSION: Future research needs to investigate commonly used but less evaluated products (e.g. chamomile, St John's Wort) and to evaluate products against or alongside conventional treatments to better reflect patient decision making....
CONCLUSION: Future research needs to investigate commonly used but less evaluated products (e.g. chamomile, St John's …
Plant-Derived Nutraceuticals in Mental Health and Brain Function: Mechanisms of Action and Therapeutic Potential.
Borrego-Ruiz A, Borrego JJ. Borrego-Ruiz A, et al. Int J Mol Sci. 2025 Sep 11;26(18):8849. doi: 10.3390/ijms26188849. Int J Mol Sci. 2025. PMID: 41009418 Free PMC article. Review.
Phytochemicals act as phytopsychobiotics, influencing mental health through gut microbiome modulation and generation of bioactive metabolites. Hypericum and curcumin exert neuroprotective, anti-inflammatory, antioxidant, and antidepressant effects. ...
Phytochemicals act as phytopsychobiotics, influencing mental health through gut microbiome modulation and generation of bioactive metabolite …
Neuroprotective and cognitive-enhancing potentials of herbal remedies: Focus on St. John's wort, green tea, and Ashwagandha.
Ahmed M. Ahmed M. Neurotoxicol Teratol. 2025 Sep-Oct;111:107549. doi: 10.1016/j.ntt.2025.107549. Epub 2025 Aug 25. Neurotoxicol Teratol. 2025. PMID: 40865615 Review.
This review focuses on three widely studied herbal agents, including St. John's Wort (Hypericum perforatum), Green Tea (Camellia sinensis), and Ashwagandha (Withania somnifera) and evaluates their mechanisms in promoting brain health. St. …
This review focuses on three widely studied herbal agents, including St. John's Wort (Hypericum perforatu …
Naturally occurring seco- and nor-polycyclic polyprenylated acylphloroglucinols: distribution, structural diversity, andbiological activity.
Duan Y, Tang Y, Qi C, Zhang Y. Duan Y, et al. Chin J Nat Med. 2025 Jul;23(7):824-837. doi: 10.1016/S1875-5364(25)60911-3. Chin J Nat Med. 2025. PMID: 40653323 Review.
As of June 2023, 200 compounds have been isolated from four genera, with Hypericum being the primary source. Notably, 115 of these compounds were identified in the past four years, indicating a significant increase in research activity. ...
As of June 2023, 200 compounds have been isolated from four genera, with Hypericum being the primary source. Notably, 115 of these co …
Herbal medicine for treating psoriasis: A systematic review.
Anheyer M, Cramer H, Ostermann T, Längler A, Anheyer D. Anheyer M, et al. Complement Ther Med. 2025 Jun;90:103173. doi: 10.1016/j.ctim.2025.103173. Epub 2025 Apr 8. Complement Ther Med. 2025. PMID: 40210174 Free article.
Herbal interventions evaluated included Aloe vera, avocado oil, chamomile-pumpkin seed oleogel, indigo naturalis, kukui oil, mahonia aquifolium, turmeric, St. John's wort, and various complex herbal preparations. Some herbal therapies, such as Mahonia …
Herbal interventions evaluated included Aloe vera, avocado oil, chamomile-pumpkin seed oleogel, indigo naturalis, kukui oil, mahonia aquifol …
Pharmacokinetic and Pharmacodynamic Interactions between Food or Herbal Products and Oral Anticoagulants: Evidence Review, Practical Recommendations, and Knowledge Gaps.
Talasaz AH, McGonagle B, HajiQasemi M, Ghelichkhan ZA, Sadeghipour P, Rashedi S, Cuker A, Lech T, Goldhaber SZ, Jennings DL, Piazza G, Bikdeli B. Talasaz AH, et al. Semin Thromb Hemost. 2025 Jun;51(5):560-571. doi: 10.1055/s-0044-1790258. Epub 2024 Sep 17. Semin Thromb Hemost. 2025. PMID: 39288907 Free article. Review.
It is also advisable for patients to maintain highly constant intake of green leafy vegetables to ensure stable warfarin effectiveness; (3) ginger, even in small quantities (excluding commercial ginger-flavored beverages, which contain only negligible amounts of ginger), and mang …
It is also advisable for patients to maintain highly constant intake of green leafy vegetables to ensure stable warfarin effectiveness; (3) …
Hazardous Interactions Between Food, Herbs, and Drugs in the First Stage of Biotransformation: Case Reports of Adverse Drug Interactions in Humans.
Bukowska B, Grzegorowska A, Szczerkowska-Majchrzak E, Bukowski K, Kadac-Czapska K, Grembecka M, Broncel M. Bukowska B, et al. Int J Mol Sci. 2025 May 28;26(11):5188. doi: 10.3390/ijms26115188. Int J Mol Sci. 2025. PMID: 40507996 Free PMC article. Review.
For example, fruit juices, such as grapefruit juice, cranberry juice, and pomegranate juice, have been found to interact with drugs, and to particularly inhibit CYP450 activity, and commonly used herbs are known to inhibit (e.g., Astragalus membranous) or induce (e.g., Hyperic …
For example, fruit juices, such as grapefruit juice, cranberry juice, and pomegranate juice, have been found to interact with drugs, and to …
70 results