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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1990 1
1992 1
1993 2
1994 1
1995 2
1996 2
1997 1
2000 3
2001 2
2002 7
2003 2
2004 4
2005 4
2006 3
2007 8
2008 10
2009 15
2010 8
2011 6
2012 12
2013 14
2014 24
2015 33
2016 31
2017 31
2018 27
2019 19
2020 14
2021 19
2022 17
2023 1
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283 results
Results by year
Filters applied: Clinical Trial. Clear all
Page 1
Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial.
Simpson RFG, Dankiewicz J, Karamasis GV, Pelosi P, Haenggi M, Young PJ, Jakobsen JC, Bannard-Smith J, Wendel-Garcia PD, Taccone FS, Nordberg P, Wise MP, Grejs AM, Lilja G, Olsen RB, Cariou A, Lascarrou JB, Saxena M, Hovdenes J, Thomas M, Friberg H, Davies JR, Nielsen N, Keeble TR. Simpson RFG, et al. Crit Care. 2022 Nov 15;26(1):356. doi: 10.1186/s13054-022-04231-6. Crit Care. 2022. PMID: 36380332 Free PMC article. Clinical Trial.
BACKGROUND: Targeted temperature management (TTM) is recommended following cardiac arrest; however, time to target temperature varies in clinical practice. ...METHODS: In this post-hoc analysis of the TTM-2 trial, patients after out of ho …
BACKGROUND: Targeted temperature management (TTM) is recommended following cardiac arrest; however, time …
Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial.
Wolfrum S, Roedl K, Hanebutte A, Pfeifer R, Kurowski V, Riessen R, Daubmann A, Braune S, Söffker G, Bibiza-Freiwald E, Wegscheider K, Schunkert H, Thiele H, Kluge S; Hypothermia After In-Hospital Cardiac Arrest Study Group. Wolfrum S, et al. Circulation. 2022 Nov;146(18):1357-1366. doi: 10.1161/CIRCULATIONAHA.122.060106. Epub 2022 Sep 28. Circulation. 2022. PMID: 36168956 Clinical Trial.
BACKGROUND: This study was conducted to determine the effect of hypothermic temperature control after in-hospital cardiac arrest (IHCA) on mortality and functional outcome as compared with normothermia. ...The HACA in-hospital trial (Hypothermia After …
BACKGROUND: This study was conducted to determine the effect of hypothermic temperature control after in-hospital cardiac a …
Influence of temperature management at 33 °C versus normothermia on survival in patients with vasopressor support after out-of-hospital cardiac arrest: a post hoc analysis of the TTM-2 trial.
Düring J, Annborn M, Cariou A, Chew MS, Dankiewicz J, Friberg H, Haenggi M, Haxhija Z, Jakobsen JC, Langeland H, Taccone FS, Thomas M, Ullén S, Wise MP, Nielsen N. Düring J, et al. Crit Care. 2022 Jul 31;26(1):231. doi: 10.1186/s13054-022-04107-9. Crit Care. 2022. PMID: 35909163 Free PMC article. Clinical Trial.
BACKGROUND: Targeted temperature management at 33 C (TTM33) has been employed in effort to mitigate brain injury in unconscious survivors of out-of-hospital cardiac arrest (OHCA). ...Results were consistent in an imputed, adjusted sensitivity an …
BACKGROUND: Targeted temperature management at 33 C (TTM33) has been employed in effort to mitigate brain injury in unc …
Kinetics of 2 different high-sensitive troponins during targeted temperature management in out-of-hospital cardiac arrest patients with acute myocardial infarction: a post hoc sub-study of a randomised clinical trial.
Larsen AI, Grejs AM, Vistisen ST, Strand K, Skadberg Ø, Jeppesen AN, Duez CHV, Kirkegaard H, Søreide E. Larsen AI, et al. BMC Cardiovasc Disord. 2022 Jul 30;22(1):342. doi: 10.1186/s12872-022-02778-4. BMC Cardiovasc Disord. 2022. PMID: 35907787 Free PMC article. Clinical Trial.
INTRODUCTION: Short term hypothermia has been suggested to have cardio protective properties in acute myocardial infarction (AMI) by reducing infarct size as assessed by troponins. There are limited data on the kinetics of these biomarkers in comatose out-of-hospital ca …
INTRODUCTION: Short term hypothermia has been suggested to have cardio protective properties in acute myocardial infarction (AMI) by …
Outcomes after decrease in hypothermia usage for out of Hospital Cardiac arrest after targeted temperature management study.
Slagle DL, Caplan RJ, Deitchman AR. Slagle DL, et al. J Clin Monit Comput. 2023 Feb;37(1):261-266. doi: 10.1007/s10877-022-00887-1. Epub 2022 Jul 8. J Clin Monit Comput. 2023. PMID: 35802294 Clinical Trial.
OBJECTIVE: Evaluate trends in targeted temperature management with regards to temperature selection, its effect on neurologic outcomes at discharge, and compare this with recent large randomized controlled trial outcomes. ...PATIENTS: 634 adult non-tra …
OBJECTIVE: Evaluate trends in targeted temperature management with regards to temperature selection, its effect …
MicroRNA-9-3p: a novel predictor of neurological outcome after cardiac arrest.
Beske RP, Bache S, Abild Stengaard Meyer M, Kjærgaard J, Bro-Jeppesen J, Obling L, Olsen MH, Rossing M, Nielsen FC, Møller K, Nielsen N, Hassager C. Beske RP, et al. Eur Heart J Acute Cardiovasc Care. 2022 Aug 9;11(8):609-616. doi: 10.1093/ehjacc/zuac066. Eur Heart J Acute Cardiovasc Care. 2022. PMID: 35695264 Clinical Trial.
AIMS: Resuscitated out-of-hospital cardiac arrest (OHCA) patients who remain comatose after hospital arrival are at high risk of mortality due to anoxic brain injury. ...CONCLUSION: MiR-9-3p is strongly associated with neurological outcome following OHCA, and the le …
AIMS: Resuscitated out-of-hospital cardiac arrest (OHCA) patients who remain comatose after hospital arrival are at high risk …
Continuous versus routine EEG in patients after cardiac arrest: Analysis of a randomized controlled trial (CERTA).
Urbano V, Alvarez V, Schindler K, Rüegg S, Ben-Hamouda N, Novy J, Rossetti AO. Urbano V, et al. Resuscitation. 2022 Jul;176:68-73. doi: 10.1016/j.resuscitation.2022.05.017. Epub 2022 May 30. Resuscitation. 2022. PMID: 35654226 Free article. Clinical Trial.
BACKGROUND: Electroencephalography (EEG) is essential to assess prognosis in patients after cardiac arrest (CA). Use of continuous EEG (cEEG) is increasing in critically-ill patients, but it is more resource-consuming than routine EEG (rEEG). ...
BACKGROUND: Electroencephalography (EEG) is essential to assess prognosis in patients after cardiac arrest (CA). Use of contin …
Targeted temperature management after out of hospital cardiac arrest: quo vadis?
Krychtiuk KA, Fordyce CB, Hansen CM, Hassager C, Jentzer JC, Menon V, Perman SM, van Diepen S, Granger CB. Krychtiuk KA, et al. Eur Heart J Acute Cardiovasc Care. 2022 Jun 22;11(6):512-521. doi: 10.1093/ehjacc/zuac054. Eur Heart J Acute Cardiovasc Care. 2022. PMID: 35579006 Clinical Trial.
Targeted temperature management (TTM) has become a cornerstone in the treatment of comatose post-cardiac arrest patients over the last two decades. ...Subsequent large randomized trials reported no difference in outcomes between TTM at 33 vs. 36 …
Targeted temperature management (TTM) has become a cornerstone in the treatment of comatose post-cardiac arre …
Quantitative pupillometry in comatose out-of-hospital cardiac arrest patients: A post-hoc analysis of the TTH48 trial.
Paramanathan S, Grejs AM, Søreide E, Duez CHV, Jeppesen AN, Reinertsen ÅJ, Strand K, Kirkegaard H. Paramanathan S, et al. Acta Anaesthesiol Scand. 2022 Aug;66(7):880-886. doi: 10.1111/aas.14078. Epub 2022 May 29. Acta Anaesthesiol Scand. 2022. PMID: 35488868 Free PMC article. Clinical Trial.
The aim of the present sub-study was to explore the long-term prognostic value of NPi in comatose out-of-hospital cardiac arrest patients undergoing targeted temperature management (TTM). METHODS: This planned sub-study of the "Targeted …
The aim of the present sub-study was to explore the long-term prognostic value of NPi in comatose out-of-hospital cardiac arrest …
Targeted Temperature Management After In-Hospital Cardiac Arrest: An Ancillary Analysis of Targeted Temperature Management for Cardiac Arrest With Nonshockable Rhythm Trial Data.
Blanc A, Colin G, Cariou A, Merdji H, Grillet G, Girardie P, Coupez E, Dequin PF, Boulain T, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Massart N, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Reignier J, Taccone FS, Lascarrou JB. Blanc A, et al. Chest. 2022 Aug;162(2):356-366. doi: 10.1016/j.chest.2022.02.056. Epub 2022 Mar 19. Chest. 2022. PMID: 35318006 Clinical Trial.
BACKGROUND: Targeted temperature management (TTM) currently is the only treatment with demonstrated efficacy in attenuating the harmful effects on the brain of ischemia-reperfusion injury after cardiac arrest. ...STUDY DESIGN AND METHODS: We per …
BACKGROUND: Targeted temperature management (TTM) currently is the only treatment with demonstrated efficacy in attenua …
283 results