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Year Number of Results
2009 1
2010 4
2011 1
2014 1
2017 1
2023 1
2024 1
2025 1
2026 0

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11 results

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Page 1
Total Laryngeal Transplant in the Setting of Active Laryngeal Malignancy.
Lott DG, Mour GK, Grandjean DN, Zacharias SRC, Stearns EH, Chang BA, Entezami P, Hinni ML, Howard BE, Zheng M. Lott DG, et al. Mayo Clin Proc. 2024 Sep;99(9):1445-1448. doi: 10.1016/j.mayocp.2024.07.001. Epub 2024 Aug 6. Mayo Clin Proc. 2024. PMID: 39115512
Laryngeal transplant (LT) is a promising option to restore quality of life in patients with severe laryngeal dysfunction or a laryngectomy. ...The loss of these important functions frequently results in social isolation and a severe decrease in quality of life. L
Laryngeal transplant (LT) is a promising option to restore quality of life in patients with severe laryngeal dysfunction or a
The current status of human laryngeal transplantation in 2017: A state of the field review.
Krishnan G, Du C, Fishman JM, Foreman A, Lott DG, Farwell G, Belafsky P, Krishnan S, Birchall MA. Krishnan G, et al. Among authors: lott dg. Laryngoscope. 2017 Aug;127(8):1861-1868. doi: 10.1002/lary.26503. Epub 2017 Feb 22. Laryngoscope. 2017. PMID: 28224630 Review.
RESULTS: A total of 5,961 articles, following removal of duplicates, matched the search criteria and were screened, with five case reports relating to two patients, ultimately fulfilling the entry criteria. CONCLUSIONS: Two laryngeal transplants have been reported i …
RESULTS: A total of 5,961 articles, following removal of duplicates, matched the search criteria and were screened, with five case reports r …
A Heterotopic Mouse Model for Studying Laryngeal Transplantation.
Kennedy MM, Salepci E, Myers C, Strome M, Lott DG. Kennedy MM, et al. Among authors: lott dg. J Vis Exp. 2023 Jan 13;(191). doi: 10.3791/63619. J Vis Exp. 2023. PMID: 36715410
Laryngeal heterotopic transplantation, although a technically challenging procedure, offers more scientific analysis and cost benefits compared to other animal models. ...
Laryngeal heterotopic transplantation, although a technically challenging procedure, offers more scientific analysis and cost
Strategic Development of a Larynx and Trachea Transplantation Program: The Mayo Clinic Arizona Experience.
Zacharias SRC, Grandjean D, Stearns E, Mour G, Lott DG. Zacharias SRC, et al. Among authors: lott dg. Clin Transplant. 2025 Mar;39(3):e70126. doi: 10.1111/ctr.70126. Clin Transplant. 2025. PMID: 40062927
Medical advances have enabled the realization of vascularized composite allografts and to date have demonstrated reasonably successful graft survival rates. Larynx and Trachea Transplantation (LT) has long been contemplated as a therapeutic option for severe larynge …
Medical advances have enabled the realization of vascularized composite allografts and to date have demonstrated reasonably successful graft …
New mouse model for studying laryngeal transplantation.
Shipchandler TZ, Lott DG, Lorenz RR, Friedman AD, Dan O, Strome M. Shipchandler TZ, et al. Among authors: lott dg. Ann Otol Rhinol Laryngol. 2009 Jun;118(6):465-8. doi: 10.1177/000348940911800610. Ann Otol Rhinol Laryngol. 2009. PMID: 19663379
The purpose of this study was to develop a reliable surgical technique in mice to serve as a model for further study of laryngeal transplantation. METHODS: Heterotopic laryngeal transplantation was attempted in 15 immunocompetent mice by use of modific …
The purpose of this study was to develop a reliable surgical technique in mice to serve as a model for further study of laryngeal
A new mouse laryngeal transplantation rejection grading system.
Lott DG, Shipchandler TZ, Dan O, Lorenz RR, Strome M. Lott DG, et al. Laryngoscope. 2010 Jan;120(1):39-43. doi: 10.1002/lary.20661. Laryngoscope. 2010. PMID: 19877187
OBJECTIVES/HYPOTHESIS: Development of a rat laryngeal transplantation model allowed for the first total human laryngeal transplantation by the senior author in 1998. ...STUDY DESIGN: Animal study. METHODS: Thirty-one mouse laryngeal transplan
OBJECTIVES/HYPOTHESIS: Development of a rat laryngeal transplantation model allowed for the first total human laryngeal
Anti-alphabeta-T-cell receptor antibodies in the setting of laryngeal transplantation.
Strome M, Lott DG. Strome M, et al. Among authors: lott dg. Immunotherapy. 2010 Nov;2(6):835-45. doi: 10.2217/imt.10.72. Immunotherapy. 2010. PMID: 21091115 Review.
Specifically, the article focuses on its efficacy and mechanism of tolerance induction in solid tissue and composite tissue allograft transplantation with a particular focus on laryngeal transplantation....
Specifically, the article focuses on its efficacy and mechanism of tolerance induction in solid tissue and composite tissue allograft transp …
Long-term laryngeal allograft survival using low-dose everolimus.
Lott DG, Dan O, Lu L, Strome M. Lott DG, et al. Otolaryngol Head Neck Surg. 2010 Jan;142(1):72-8. doi: 10.1016/j.otohns.2009.10.019. Otolaryngol Head Neck Surg. 2010. PMID: 20096226
SUBJECTS AND METHODS: Fifteen recipient mice (five per group) were injected with everolimus (1 mg/kg/d) until euthanized at 15, 30, and 60 days posttransplantation. Five mice received transplants without immunosuppression and were euthanized at day 15. ...Everolimus alone …
SUBJECTS AND METHODS: Fifteen recipient mice (five per group) were injected with everolimus (1 mg/kg/d) until euthanized at 15, 30, a …
Ten-month laryngeal allograft survival with use of pulsed everolimus and anti-alphabeta T-cell receptor antibody immunosuppression.
Lott DG, Russell JO, Khariwala SS, Dan O, Strome M. Lott DG, et al. Ann Otol Rhinol Laryngol. 2011 Feb;120(2):131-6. doi: 10.1177/000348941112000210. Ann Otol Rhinol Laryngol. 2011. PMID: 21391426
OBJECTIVES: The risks of daily immunosuppression limit the use of laryngeal transplantation as a reconstructive option. Pulsed immunosuppressive dosing can lessen these risks. The study objective was to develop a long-term pulsing regimen that minimizes exposure to …
OBJECTIVES: The risks of daily immunosuppression limit the use of laryngeal transplantation as a reconstructive option. Pulsed …
11 results