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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 24
2011 46
2012 68
2013 106
2014 127
2015 134
2016 140
2017 148
2018 157
2019 107
2020 7
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906 results
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Page 1
Clinical Review: Loperamide Toxicity.
Wu PE, Juurlink DN. Wu PE, et al. Ann Emerg Med. 2017 Aug;70(2):245-252. doi: 10.1016/j.annemergmed.2017.04.008. Epub 2017 May 13. Ann Emerg Med. 2017. PMID: 28506439 Review.
Although it is relatively safe at therapeutic doses, increasing reports describe its misuse and abuse at very high doses either for euphoric effects or to attenuate symptoms of opioid withdrawal. ...In patients who survive loperamide toxicity, consideration should b …
Although it is relatively safe at therapeutic doses, increasing reports describe its misuse and abuse at very high doses eithe …
The Opioid Epidemic in the United States.
Wilkerson RG, Kim HK, Windsor TA, Mareiniss DP. Wilkerson RG, et al. Emerg Med Clin North Am. 2016 May;34(2):e1-e23. doi: 10.1016/j.emc.2015.11.002. Epub 2016 Feb 17. Emerg Med Clin North Am. 2016. PMID: 27133253 Review.
There is an epidemic of opioid abuse. This article discusses the history of opioid use. Abusers of opioids are at great risk of harm. There have been increasing legislative efforts to curb this abuse and we present a review of the current state of these laws. …
There is an epidemic of opioid abuse. This article discusses the history of opioid use. Abusers of opioids are at great risk o …
Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults: 2015 National Survey on Drug Use and Health.
Han B, Compton WM, Blanco C, Crane E, Lee J, Jones CM. Han B, et al. Ann Intern Med. 2017 Sep 5;167(5):293-301. doi: 10.7326/M17-0865. Epub 2017 Aug 1. Ann Intern Med. 2017. PMID: 28761945
OBJECTIVE: To estimate the prevalence of prescription opioid use, misuse, and use disorders and motivations for misuse among U.S. adults. ...Among adults with prescription opioid use, 12.5% reported misuse; of these, 16.7% r …
OBJECTIVE: To estimate the prevalence of prescription opioid use, misuse, and use disorders and motivations for …
Introduction to the opioid epidemic: the economic burden on the healthcare system and impact on quality of life.
Hagemeier NE. Hagemeier NE. Am J Manag Care. 2018 May;24(10 Suppl):S200-S206. Am J Manag Care. 2018. PMID: 29851449 Free article. Review.
Because of overprescribing and misuse, an opioid epidemic has developed in the United States. The health and economic burdens of opioid abuse on individuals, their families, and society are substantial. Part 1 of this supplement will provide a background on the burd …
Because of overprescribing and misuse, an opioid epidemic has developed in the United States. The health and economic burdens of opio …
Cancer pain management: safe and effective use of opioids.
Bruera E, Paice JA. Bruera E, et al. Am Soc Clin Oncol Educ Book. 2015:e593-9. doi: 10.14694/EdBook_AM.2015.35.e593. Am Soc Clin Oncol Educ Book. 2015. PMID: 25993228 Free article. Review.
An emerging concern is overtreatment-the excessive and prolonged use of opioids in patients when these agents may produce more harm than benefit. ...Caring for patients with substance misuse requires compassionate, multidisciplinary care, with input from supportive …
An emerging concern is overtreatment-the excessive and prolonged use of opioids in patients when these agents may produce more harm t …
The Prescription Opioid Addiction Treatment Study: What have we learned.
Weiss RD, Rao V. Weiss RD, et al. Drug Alcohol Depend. 2017 Apr 1;173 Suppl 1(Suppl 1):S48-S54. doi: 10.1016/j.drugalcdep.2016.12.001. Drug Alcohol Depend. 2017. PMID: 28363320 Free PMC article. Clinical Trial.
BACKGROUND: The multi-site Prescription Opioid Addiction Treatment Study (POATS), conducted by the National Drug Abuse Treatment Clinical Trials Network, was the largest clinical trial yet conducted with patients dependent upon prescription opioids (N= …
BACKGROUND: The multi-site Prescription Opioid Addiction Treatment Study (POATS), conducted by the National Drug Abuse
Worldwide Prevalence and Trends in Unintentional Drug Overdose: A Systematic Review of the Literature.
Martins SS, Sampson L, Cerdá M, Galea S. Martins SS, et al. Am J Public Health. 2015 Nov;105(11):e29-49. doi: 10.2105/AJPH.2015.302843. Am J Public Health. 2015. PMID: 26451760 Free PMC article. Review.
An overall trend of increasing deaths from prescription opioid use and decreasing deaths from illicit drug use in the past several years has been noted across most of the literature. ...Several other countries need to collect in a systematic and contin …
An overall trend of increasing deaths from prescription opioid use and decreasing deaths from illicit drug use i …
Opioid agonist treatment for pharmaceutical opioid dependent people.
Nielsen S, Larance B, Degenhardt L, Gowing L, Kehler C, Lintzeris N. Nielsen S, et al. Cochrane Database Syst Rev. 2016 May 9;(5):CD011117. doi: 10.1002/14651858.CD011117.pub2. Cochrane Database Syst Rev. 2016. PMID: 27157143 Review.
People dependent on pharmaceutical opioids appear to differ in important ways from people who use heroin, yet most opioid agonist treatment research has been conducted in people who use heroin. ...MAIN RESULTS: We identified six randomised controlled trials that met …
People dependent on pharmaceutical opioids appear to differ in important ways from people who use heroin, yet most opioid agonist tre …
Chronic Opioid Use After Surgery: Implications for Perioperative Management in the Face of the Opioid Epidemic.
Hah JM, Bateman BT, Ratliff J, Curtin C, Sun E. Hah JM, et al. Anesth Analg. 2017 Nov;125(5):1733-1740. doi: 10.1213/ANE.0000000000002458. Anesth Analg. 2017. PMID: 29049117 Free PMC article. Review.
In this paper, we discuss the consequences of chronic opioid use after surgery and present an analysis of the extent to which surgery has been associated with chronic opioid use. We follow with a discussion of the risk factors that are associated with chronic opioid …
In this paper, we discuss the consequences of chronic opioid use after surgery and present an analysis of the extent to which surgery …
America's Opioid Epidemic: Supply and Demand Considerations.
Clark DJ, Schumacher MA. Clark DJ, et al. Anesth Analg. 2017 Nov;125(5):1667-1674. doi: 10.1213/ANE.0000000000002388. Anesth Analg. 2017. PMID: 29049112 Review.
Medical and lay public sentiment have become more cautious with respect to prescription opioid use in the past few years, but a comprehensive strategy to reduce our reliance on prescription opioids is lacking. ...Key supply-side measures include avoiding over …
Medical and lay public sentiment have become more cautious with respect to prescription opioid use in the past few years, but …
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