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A DNA-Binding Protein Tunes Septum Placement during Bacillus subtilis Sporulation.
Brown EE, Miller AK, Krieger IV, Otto RM, Sacchettini JC, Herman JK. Brown EE, et al. Among authors: herman jk. J Bacteriol. 2019 Jul 24;201(16):e00287-19. doi: 10.1128/JB.00287-19. Print 2019 Aug 15. J Bacteriol. 2019. PMID: 31160399 Free PMC article.
Sporulating cells expressing the rLOF variants in place of wild-type RefZ phenocopied a ΔrefZ mutant, suggesting that RefZ acts through an FtsZ-dependent mechanism. The crystal structure of RefZ was solved, and wild-type RefZ and the rLOF variants were …
Sporulating cells expressing the rLOF variants in place of wild-type RefZ phenocopied a ΔrefZ mutant, suggesting that RefZ act …
RefZ facilitates the switch from medial to polar division during spore formation in Bacillus subtilis.
Wagner-Herman JK, Bernard R, Dunne R, Bisson-Filho AW, Kumar K, Nguyen T, Mulcahy L, Koullias J, Gueiros-Filho FJ, Rudner DZ. Wagner-Herman JK, et al. J Bacteriol. 2012 Sep;194(17):4608-18. doi: 10.1128/JB.00378-12. Epub 2012 Jun 22. J Bacteriol. 2012. PMID: 22730127 Free PMC article.
Here, we describe a sporulation-induced protein, RefZ, that facilitates the switch from a medial to a polar FtsZ ring placement. ...Mutations in FtsZ specifically suppress RefZ-dependent division inhibition, suggesting that RefZ may target FtsZ. During sporul …
Here, we describe a sporulation-induced protein, RefZ, that facilitates the switch from a medial to a polar FtsZ ring placement. ...M …
A DNA-binding protein defines the precise region of chromosome capture during Bacillus sporulation.
Miller AK, Brown EE, Mercado BT, Herman JK. Miller AK, et al. Among authors: herman jk. Mol Microbiol. 2016 Jan;99(1):111-22. doi: 10.1111/mmi.13217. Epub 2015 Oct 14. Mol Microbiol. 2016. PMID: 26360512 Free article.
RefZ is conserved across the Bacillus genus and remains functional as an inhibitor of cell division in a species-swapping experiment. ...In B. subtilis, the RBMs flank the region of the chromosome captured at the time of cell division, and we find that RefZ binds th
RefZ is conserved across the Bacillus genus and remains functional as an inhibitor of cell division in a species-swapping experiment.
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