Road to precision: recombinase-based targeting technologies for genome engineering.
Curr Opin Biotechnol. 2007 Oct;18(5):411-9. doi: 10.1016/j.copbio.2007.07.013. Epub 2007 Sep 27.
Curr Opin Biotechnol. 2007.
PMID: 17904350
Review.
In the past years, recombinase-based approaches for integrating transgenes into defined chromosomal loci of mammalian cells have gained increasing attention. ...This review focuses on the current state of targeting strategies including RMCE employing site-specific recom …
In the past years, recombinase-based approaches for integrating transgenes into defined chromosomal loci of mammalian cells have gain …