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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2001 1
2002 2
2003 2
2004 9
2005 11
2006 24
2007 36
2008 26
2009 34
2010 44
2011 44
2012 50
2013 46
2014 45
2015 48
2016 54
2017 41
2018 38
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2020 57
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2022 78
2023 67
2024 21

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768 results

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Page 1
Role of Toll-like receptors in the pathogenesis of COVID-19.
Khanmohammadi S, Rezaei N. Khanmohammadi S, et al. J Med Virol. 2021 May;93(5):2735-2739. doi: 10.1002/jmv.26826. Epub 2021 Feb 9. J Med Virol. 2021. PMID: 33506952 Free PMC article. Review.
Activation of TLR pathways leads to secretion of pro-inflammatory cytokines, such as interleukin-1 (IL-1), IL-6, and tumor necrosis factor-alpha, as well as type 1 interferon. Different TLRs, like TLR2, TLR3, TLR4, TLR6, TLR7, TLR8, and TLR9 are potentially important in CO …
Activation of TLR pathways leads to secretion of pro-inflammatory cytokines, such as interleukin-1 (IL-1), IL-6, and tumor necrosis factor-a …
C-type lectins and extracellular vesicles in virus-induced NETosis.
Sung PS, Hsieh SL. Sung PS, et al. J Biomed Sci. 2021 Jun 11;28(1):46. doi: 10.1186/s12929-021-00741-7. J Biomed Sci. 2021. PMID: 34116654 Free PMC article. Review.
The DV-activated EXOs (DV-EXOs) and MVs (DV-MVs) stimulate CLEC5A and Toll-like receptor 2 (TLR2), respectively, to enhance NET formation and inflammatory reactions. Thus, EVs from virus-activated platelets (PLT-EVs) are potent endogenous danger signals, and blockad …
The DV-activated EXOs (DV-EXOs) and MVs (DV-MVs) stimulate CLEC5A and Toll-like receptor 2 (TLR2), respectively, to enhance NET forma …
Viral proteins recognized by different TLRs.
Zhou R, Liu L, Wang Y. Zhou R, et al. J Med Virol. 2021 Nov;93(11):6116-6123. doi: 10.1002/jmv.27265. Epub 2021 Aug 17. J Med Virol. 2021. PMID: 34375002 Review.
Virus invasion activates the host's innate immune response, inducing the production of numerous cytokines and interferons to eliminate pathogens. ...These viruses are all enveloped, including respiratory syncytial virus, hepatitis C virus, measles v
Virus invasion activates the host's innate immune response, inducing the production of numerous cytokines and interferons to eliminat
What triggers inflammation in COVID-19?
Sawa T, Akaike T. Sawa T, et al. Elife. 2022 Jan 20;11:e76231. doi: 10.7554/eLife.76231. Elife. 2022. PMID: 35049500 Free PMC article.
TLRs: Innate Immune Sentries against SARS-CoV-2 Infection.
Mantovani S, Oliviero B, Varchetta S, Renieri A, Mondelli MU. Mantovani S, et al. Int J Mol Sci. 2023 Apr 29;24(9):8065. doi: 10.3390/ijms24098065. Int J Mol Sci. 2023. PMID: 37175768 Free PMC article. Review.
It has been demonstrated that they contribute to the dysregulated immune response observed in patients with severe COVID-19. TLR2, TLR3, TLR4 and TLR7 have been associated with COVID-19 severity. Here, we review the role of TLRs in the etiology and pathogenesis of COVID-19 …
It has been demonstrated that they contribute to the dysregulated immune response observed in patients with severe COVID-19. TLR2, TL …
TLR2, as a Pathogen Recognition Receptor, Plays Critical Roles in Hepatitis B Outcome.
Naghib M, Kariminik A, Kazemi Arababadi M. Naghib M, et al. Viral Immunol. 2022 Jan-Feb;35(1):15-23. doi: 10.1089/vim.2021.0141. Epub 2022 Jan 11. Viral Immunol. 2022. PMID: 35020525 Review.
Therefore, it has been hypothesized that TLR2 may participate in both immune response against HBV and induction of the virus-related hepatic complications. ...However, recent studies demonstrated that the molecule can fight against HCC and liver cirrhosis. Collectiv …
Therefore, it has been hypothesized that TLR2 may participate in both immune response against HBV and induction of the virus-r …
Interplay between dengue virus and Toll-like receptors, RIG-I/MDA5 and microRNAs: Implications for pathogenesis.
Urcuqui-Inchima S, Cabrera J, Haenni AL. Urcuqui-Inchima S, et al. Antiviral Res. 2017 Nov;147:47-57. doi: 10.1016/j.antiviral.2017.09.017. Epub 2017 Sep 28. Antiviral Res. 2017. PMID: 28965915 Review.
Recognition by TLR2 and TLR4 also promotes the activation of other intracellular pathways and alters viral replication in an interferon-independent manner. ...To accomplish this, miRNAs bind either directly to viral RNA, through base-pair complementarity affecting translat …
Recognition by TLR2 and TLR4 also promotes the activation of other intracellular pathways and alters viral replication in an interfer …
The anti-inflammatory and antiviral properties of anionic pulmonary surfactant phospholipids.
Numata M, Kandasamy P, Voelker DR. Numata M, et al. Immunol Rev. 2023 Aug;317(1):166-186. doi: 10.1111/imr.13207. Epub 2023 May 5. Immunol Rev. 2023. PMID: 37144896 Review.
We have reported that one of the most dominant molecular species of PG, palmitoyl-oleoyl-phosphatidylglycerol (POPG) and PI inhibit inflammatory responses induced by multiple toll-like receptors (TLR2/1, TLR3, TLR4, and TLR2/6) by interacting with subsets of multipr …
We have reported that one of the most dominant molecular species of PG, palmitoyl-oleoyl-phosphatidylglycerol (POPG) and PI inhibit inflamma …
CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections.
Sung PS, Hsieh SL. Sung PS, et al. Front Immunol. 2019 Dec 6;10:2867. doi: 10.3389/fimmu.2019.02867. eCollection 2019. Front Immunol. 2019. PMID: 31867016 Free PMC article. Review.
Although CLEC2 has been reported to interact with type I immunodeficiency virus (HIV-1), its role in viral infections is still unclear. CLEC5A binds to fucose and mannose moieties of dengue virus membrane glycans, as well as to N-acetylglucosamine (GlcNAc)/N-acetylm …
Although CLEC2 has been reported to interact with type I immunodeficiency virus (HIV-1), its role in viral infections is still unclea …
768 results