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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 1
2009 2
2010 10
2011 6
2012 9
2013 10
2014 10
2015 5
2016 18
2017 15
2018 5
2019 11
2020 11
2021 1
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106 results
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COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning.
Ong E, Wong MU, Huffman A, He Y. Ong E, et al. Among authors: he y. Front Immunol. 2020 Jul 3;11:1581. doi: 10.3389/fimmu.2020.01581. eCollection 2020. Front Immunol. 2020. PMID: 32719684 Free PMC article.
Besides the commonly used S protein, the nsp3 protein has not been tested in any coronavirus vaccine studies and was selected for further investigation. ...We also propose that an "Sp/Nsp cocktail vaccine" containing a structural protein(s) (Sp) and a …
Besides the commonly used S protein, the nsp3 protein has not been tested in any coronavirus vaccine studies and was selected …
COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning.
Ong E, Wong MU, Huffman A, He Y. Ong E, et al. Among authors: he y. bioRxiv. 2020 Mar 21:2020.03.20.000141. doi: 10.1101/2020.03.20.000141. Preprint. bioRxiv. 2020. PMID: 32511333 Free PMC article. Updated.
Our literature and clinical trial survey showed that the whole virus, as well as the spike (S) protein, nucleocapsid (N) protein, and membrane protein, have been tested for vaccine development against SARS and MERS. ...Besides the commonly used S protein, the …
Our literature and clinical trial survey showed that the whole virus, as well as the spike (S) protein, nucleocapsid (N) protein, and …
A statistical analysis of vaccine-adverse event data.
Ren JJ, Sun T, He Y, Zhang Y. Ren JJ, et al. Among authors: he y. BMC Med Inform Decis Mak. 2019 May 28;19(1):101. doi: 10.1186/s12911-019-0818-8. BMC Med Inform Decis Mak. 2019. PMID: 31138219 Free PMC article.
BACKGROUND: Vaccination has been one of the most successful public health interventions to date, and the U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) currently contains more than 500,000 reports for post-vaccination adverse events that o …
BACKGROUND: Vaccination has been one of the most successful public health interventions to date, and the U.S. FDA/CDC Vacci
Vaccine and Drug Ontology Studies (VDOS 2014).
Tao C, He Y, Arabandi S. Tao C, et al. Among authors: he y. J Biomed Semantics. 2016 Feb 25;7:6. doi: 10.1186/s13326-015-0039-8. eCollection 2016. J Biomed Semantics. 2016. PMID: 26918107 Free PMC article.
The "Vaccine and Drug Ontology Studies" (VDOS) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. ...Over the last decade, tremendous efforts have been made in the biomedical ontology community …
The "Vaccine and Drug Ontology Studies" (VDOS) international workshop series focuses on vaccine- and drug-related on
Emerging vaccine informatics.
He Y, Rappuoli R, De Groot AS, Chen RT. He Y, et al. J Biomed Biotechnol. 2010;2010:218590. doi: 10.1155/2010/218590. Epub 2011 Jun 15. J Biomed Biotechnol. 2010. PMID: 21772787 Free PMC article. Review.
Mathematical simulations have been used to model host-pathogen interactions and improve vaccine production and vaccination protocols. Computational methods have also been used for development of immunization registries or immunization information systems, assessment …
Mathematical simulations have been used to model host-pathogen interactions and improve vaccine production and vaccination pro …
A 2018 workshop: vaccine and drug ontology studies (VDOS 2018).
Hur J, Tao C, He Y. Hur J, et al. Among authors: he y. BMC Bioinformatics. 2019 Dec 23;20(Suppl 21):705. doi: 10.1186/s12859-019-3191-9. BMC Bioinformatics. 2019. PMID: 31865905 Free PMC article.
This Editorial first introduces the background of the vaccine and drug relations and how biomedical terminologies and ontologies have been used to support their studies. The history of the seven workshops, initially named VDOSME, and then named VDOS, is also summari …
This Editorial first introduces the background of the vaccine and drug relations and how biomedical terminologies and ontologies
Ontology-supported research on vaccine efficacy, safety and integrative biological networks.
He Y. He Y. Expert Rev Vaccines. 2014 Jul;13(7):825-41. doi: 10.1586/14760584.2014.923762. Epub 2014 Jun 7. Expert Rev Vaccines. 2014. PMID: 24909153 Free PMC article. Review.
Several community-based ontologies (including Vaccine Ontology, Ontology of Adverse Events and Ontology of Vaccine Adverse Events) have been developed to support vaccine and adverse event representation, classification, data integr …
Several community-based ontologies (including Vaccine Ontology, Ontology of Adverse Events and Ontology o …
Ontology-Based Vaccine Adverse Event Representation and Analysis.
Xie J, He Y. Xie J, et al. Among authors: he y. Adv Exp Med Biol. 2017;1028:89-103. doi: 10.1007/978-981-10-6041-0_6. Adv Exp Med Biol. 2017. PMID: 29058218 Review.
To represent and analyze vaccine adverse events (VAEs), our research group has initiated and led the development of a community-based ontology: the Ontology of Adverse Events (OAE) (He et al., J Biomed Semant 5:29, 2014). The OAE has been found to have advant …
To represent and analyze vaccine adverse events (VAEs), our research group has initiated and led the development of a community-based …
VIO: ontology classification and study of vaccine responses given various experimental and analytical conditions.
Ong E, Sun P, Berke K, Zheng J, Wu G, He Y. Ong E, et al. Among authors: he y. BMC Bioinformatics. 2019 Dec 23;20(Suppl 21):704. doi: 10.1186/s12859-019-3194-6. BMC Bioinformatics. 2019. PMID: 31865910 Free PMC article.
Different experimental and analysis conditions were likely contributed to the observed differences. To investigate this issue, we developed a Vaccine Investigation Ontology (VIO), and applied VIO to classify the different variables and relations among these variable …
Different experimental and analysis conditions were likely contributed to the observed differences. To investigate this issue, we developed …
Databases and in silico tools for vaccine design.
He Y, Xiang Z. He Y, et al. Methods Mol Biol. 2013;993:115-27. doi: 10.1007/978-1-62703-342-8_8. Methods Mol Biol. 2013. PMID: 23568467 Review.
Vaccine-related databases include databases of vaccines and vaccine components. ...Vaccine information and resources can be integrated with Vaccine Ontology (VO). ...
Vaccine-related databases include databases of vaccines and vaccine components. ...Vaccine information and resou
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