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13 results
Use COVID-19 filters from PubMed Clinical Queries to refine your search See more SARS-CoV-2 literature, sequence, and clinical content from NCBI
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Page 1
A new framework for host-pathogen interaction research.
Yu H, Li L, Huffman A, Beverley J, Hur J, Merrell E, Huang HH, Wang Y, Liu Y, Ong E, Cheng L, Zeng T, Zhang J, Li P, Liu Z, Wang Z, Zhang X, Ye X, Handelman SK, Sexton J, Eaton K, Higgins G, Omenn GS, Athey B, Smith B, Chen L, He Y. Yu H, et al. Among authors: he y. Front Immunol. 2022 Dec 15;13:1066733. doi: 10.3389/fimmu.2022.1066733. eCollection 2022. Front Immunol. 2022. PMID: 36591248 Free PMC article.
As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting proces …
As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infe …
A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology.
He Y, Yu H, Huffman A, Lin AY, Natale DA, Beverley J, Zheng L, Perl Y, Wang Z, Liu Y, Ong E, Wang Y, Huang P, Tran L, Du J, Shah Z, Shah E, Desai R, Huang HH, Tian Y, Merrell E, Duncan WD, Arabandi S, Schriml LM, Zheng J, Masci AM, Wang L, Liu H, Smaili FZ, Hoehndorf R, Pendlington ZM, Roncaglia P, Ye X, Xie J, Tang YW, Yang X, Peng S, Zhang L, Chen L, Hur J, Omenn GS, Athey B, Smith B. He Y, et al. J Biomed Semantics. 2022 Oct 21;13(1):25. doi: 10.1186/s13326-022-00279-z. J Biomed Semantics. 2022. PMID: 36271389 Free PMC article.
CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms …
CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Pr …
Profiling COVID-19 Vaccine Adverse Events by Statistical and Ontological Analysis of VAERS Case Reports.
Guo W, Deguise J, Tian Y, Huang PC, Goru R, Yang Q, Peng S, Zhang L, Zhao L, Xie J, He Y. Guo W, et al. Among authors: he y. Front Pharmacol. 2022 Jun 24;13:870599. doi: 10.3389/fphar.2022.870599. eCollection 2022. Front Pharmacol. 2022. PMID: 35814246 Free PMC article.
Since the beginning of the COVID-19 pandemic, vaccines have been developed to mitigate the spread of SARS-CoV-2, the virus that causes COVID-19. ...Notably, severe COVID-19 vaccine AEs (including …
Since the beginning of the COVID-19 pandemic, vaccines have been developed to mitigate the spread of SARS-CoV …
COVID-19 vaccine design using reverse and structural vaccinology, ontology-based literature mining and machine learning.
Huffman A, Ong E, Hur J, D'Mello A, Tettelin H, He Y. Huffman A, et al. Among authors: he y. Brief Bioinform. 2022 Jul 18;23(4):bbac190. doi: 10.1093/bib/bbac190. Brief Bioinform. 2022. PMID: 35649389
Rational vaccine design, especially vaccine antigen identification and optimization, is critical to successful and efficient vaccine development against various infectious diseases including coronavirus disease 2019 (COVID-19). ... …
Rational vaccine design, especially vaccine antigen identification and optimization, is critical to successful and efficient …
Differential COVID-19 Symptoms Given Pandemic Locations, Time, and Comorbidities During the Early Pandemic.
Wang Y, Zhang F, Byrd JB, Yu H, Ye X, He Y. Wang Y, et al. Among authors: he y. Front Med (Lausanne). 2022 Jan 28;9:770031. doi: 10.3389/fmed.2022.770031. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35155491 Free PMC article.
BACKGROUND: COVID-19 pandemic is disaster to public health worldwide. Better perspective on COVID's features early in its course-prior to the development of vaccines and widespread variants-may prove useful in the understanding of future pandemi …
BACKGROUND: COVID-19 pandemic is disaster to public health worldwide. Better perspective on COVID's features ear …
Cov19VaxKB: A Web-based Integrative COVID-19 Vaccine Knowledge Base.
Huang PC, Goru R, Huffman A, Yu Lin A, Cooke MF, He Y. Huang PC, et al. Among authors: he y. Vaccine X. 2021 Dec 28;10:100139. doi: 10.1016/j.jvacx.2021.100139. Online ahead of print. Vaccine X. 2021. PMID: 34981039 Free PMC article.
The development of SARS-CoV-2 vaccines during the COVID-19 pandemic has prompted the emergence of COVID-19 vaccine data. ...Cov19VaxKB features comprehensive lists of COVID-19 vaccines, vaccine …
The development of SARS-CoV-2 vaccines during the COVID-19 pandemic has prompted the emergence of …
Vaccine Design by Reverse Vaccinology and Machine Learning.
Ong E, He Y. Ong E, et al. Among authors: he y. Methods Mol Biol. 2022;2414:1-16. doi: 10.1007/978-1-0716-1900-1_1. Methods Mol Biol. 2022. PMID: 34784028
Reverse vaccinology (RV) is the state-of-the-art vaccine development strategy that starts with predicting vaccine antigens by bioinformatics analysis of the whole genome of a pathogen of interest. ...Vaxign-ML is also available as a command-based software package fo …
Reverse vaccinology (RV) is the state-of-the-art vaccine development strategy that starts with predicting vaccine antigens by …
Visual comprehension and orientation into the COVID-19 CIDO ontology.
Zheng L, Perl Y, He Y, Ochs C, Geller J, Liu H, Keloth VK. Zheng L, et al. Among authors: he y. J Biomed Inform. 2021 Aug;120:103861. doi: 10.1016/j.jbi.2021.103861. Epub 2021 Jul 2. J Biomed Inform. 2021. PMID: 34224898 Free PMC article.
The current intensive research on potential remedies and vaccinations for COVID-19 would greatly benefit from an ontology of standardized COVID terms. The Coronavirus Infectious Disease Ontology (CIDO) is the largest among several COVID o …
The current intensive research on potential remedies and vaccinations for COVID-19 would greatly benefit from an ontolo …
Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning.
Ong E, Cooke MF, Huffman A, Xiang Z, Wong MU, Wang H, Seetharaman M, Valdez N, He Y. Ong E, et al. Among authors: he y. Nucleic Acids Res. 2021 Jul 2;49(W1):W671-W678. doi: 10.1093/nar/gkab279. Nucleic Acids Res. 2021. PMID: 34009334 Free PMC article.
Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV) is a state-of-the-art technique to predict vaccine candidates from pathogen's genome(s). ...Vaxign2 also includes precomputed results from approximately 1 milli …
Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV) is a state-of-the-art technique to predic …
Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering.
Ong E, Huang X, Pearce R, Zhang Y, He Y. Ong E, et al. Among authors: he y. Comput Struct Biotechnol J. 2021;19:518-529. doi: 10.1016/j.csbj.2020.12.039. Epub 2020 Dec 31. Comput Struct Biotechnol J. 2021. PMID: 33398234 Free PMC article.
The development of effective and safe vaccines is the ultimate way to efficiently stop the ongoing COVID-19 pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 …
The development of effective and safe vaccines is the ultimate way to efficiently stop the ongoing COVID-19 pandemic, w …
13 results