Longitudinal study of physiologic insulin resistance and metabolic changes of puberty.
Pediatr Res. 2006.
PMID: 17065576
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Longitudinal study of physiologic insulin resistance and metabolic changes of puberty.
Pediatr Res. 2006 Dec;60(6):759-63. doi: 10.1203/01.pdr.0000246097.73031.27. Epub 2006 Oct 25.
Pediatr Res. 2006.
PMID: 17065576
Cross-sectional studies have shown that 1) adolescents are insulin resistant compared with prepubertal children and adults, 2) pubertal insulin resistance is likely mediated by growth hormone (GH), and 3) pubertal insulin resistance is as …
Cross-sectional studies have shown that 1) adolescents are insulin resistant compared with prepubertal children and adults, 2) …
The Impact of Obesity On Insulin Sensitivity and Secretion During Pubertal Progression: A Longitudinal Study.
J Clin Endocrinol Metab. 2020 May 1;105(5):e2061-8. doi: 10.1210/clinem/dgaa043.
J Clin Endocrinol Metab. 2020.
PMID: 31996919
Free PMC article.
CONTEXT: Physiologic changes in glucose metabolism are well-described to occur during puberty. ...DESIGN: Longitudinal observational study evaluating youth from early puberty (Tanner [T]2-T3) until puberty completion (T5). . …
CONTEXT: Physiologic changes in glucose metabolism are well-described to occur during puberty. ...DESIGN: Lon …
Branched-Chain and Aromatic Amino Acids Are Associated With Insulin Resistance During Pubertal Development in Girls.
J Adolesc Health. 2019 Sep;65(3):337-343. doi: 10.1016/j.jadohealth.2019.01.030. Epub 2019 Mar 21.
J Adolesc Health. 2019.
PMID: 30905504
This study aimed to assess whether circulating amino acids associate with insulin resistance during pubertal development. ...Insulin resistance was determined by the homeostatic model assessment of insulin resistance (HOMA-IR). ...
This study aimed to assess whether circulating amino acids associate with insulin resistance during pubertal developmen …
Pubertal increment in insulin resistance is negatively related to lumbar bone mineral density in 18-year-old males.
Osteoporos Int. 2023 Jan;34(1):161-170. doi: 10.1007/s00198-022-06591-9. Epub 2022 Nov 11.
Osteoporos Int. 2023.
PMID: 36367566
Transient insulin resistance seen during puberty is expected to favour body growth, but our results show that increment in insulin resistance even in physiological ranges during puberty might compromise lumbar spine bone mineral de …
Transient insulin resistance seen during puberty is expected to favour body growth, but our results show that increment …
Association of Apelin Levels in Overweight-obese Children with Pubertal Development, but Not with Insulin Sensitivity: 6.5 Years Follow up Evaluation.
Endocr Res. 2020 Nov;45(4):233-240. doi: 10.1080/07435800.2020.1804929. Epub 2020 Aug 13.
Endocr Res. 2020.
PMID: 32791927
CONCLUSIONS: Apelin levels decrease significantly with pubertal development, whilst body-weight in children and adolescents did not determine changes in apelin. Reduced levels of apelin in children and adolescents may therefore represent a necessary response to maintain th …
CONCLUSIONS: Apelin levels decrease significantly with pubertal development, whilst body-weight in children and adolescents did not determin …
One-year treatment with gonadotropin-releasing hormone analogues does not affect body mass index, insulin sensitivity or lipid profile in girls with central precocious puberty.
J Pediatr Endocrinol Metab. 2019 Feb 25;32(2):181-186. doi: 10.1515/jpem-2018-0290.
J Pediatr Endocrinol Metab. 2019.
PMID: 30699070
Background Puberty is associated with a physiological decline in insulin sensitivity (IS). ...Methods We present a prospective longitudinal study of CPP girls. The standard oral glucose tolerance test, homeostatic model assessment of insulin …
Background Puberty is associated with a physiological decline in insulin sensitivity (IS). ...Methods We present a pros …
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