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Photobiomodulation and Cancer: What Is the Truth?
Hamblin MR, Nelson ST, Strahan JR. Hamblin MR, et al. Photomed Laser Surg. 2018 May;36(5):241-245. doi: 10.1089/pho.2017.4401. Epub 2018 Feb 21. Photomed Laser Surg. 2018. PMID: 29466089 Free PMC article. Review.
BACKGROUND: Photobiomodulation (PBM) therapy is a rapidly growing approach to stimulate healing, reduce pain, increase athletic performance, and improve general wellness. ...
BACKGROUND: Photobiomodulation (PBM) therapy is a rapidly growing approach to stimulate healing, reduce pain, increase athletic perfo …
Photobiomodulation and Oral Mucositis: A Systematic Review.
Cronshaw M, Parker S, Anagnostaki E, Mylona V, Lynch E, Grootveld M. Cronshaw M, et al. Dent J (Basel). 2020 Aug 5;8(3):87. doi: 10.3390/dj8030087. Dent J (Basel). 2020. PMID: 32764305 Free PMC article. Review.
Moreover, there is an extended discussion available on the treatment care rationale of photobiomodulation (PBM), and its adjunctive association with OM. In conclusion, early prophylactic application offers clear advantages in clinical management. ...
Moreover, there is an extended discussion available on the treatment care rationale of photobiomodulation (PBM), and its adjunctive a …
Photobiomodulation: Evolution and Adaptation.
Lipko NB. Lipko NB. Photobiomodul Photomed Laser Surg. 2022 Apr;40(4):213-233. doi: 10.1089/photob.2021.0145. Epub 2022 Mar 29. Photobiomodul Photomed Laser Surg. 2022. PMID: 35353639 Review.
Photobiomodulation (PBM) can be described as the intentional use of low-power laser or light-emitting diode light in the visible and near-infrared light spectra as a medical treatment to living biological tissues. ...
Photobiomodulation (PBM) can be described as the intentional use of low-power laser or light-emitting diode light in the visible and
Photobiomodulation and Sports: Results of a Narrative Review.
Ailioaie LM, Litscher G. Ailioaie LM, et al. Life (Basel). 2021 Dec 3;11(12):1339. doi: 10.3390/life11121339. Life (Basel). 2021. PMID: 34947870 Free PMC article. Review.
Benefits of photobiomodulation (PBM) have been known for several decades. More recently, PBM applied in sports offers a special chance to support the modeling of the performance and recovery. ...To evaluate and identify all risk factors and the influence of PBM on health a …
Benefits of photobiomodulation (PBM) have been known for several decades. More recently, PBM applied in sports offers a special chanc …
Photobiomodulation for Hypertension and Alzheimer's Disease.
Valverde A, Mitrofanis J. Valverde A, et al. J Alzheimers Dis. 2022;90(3):1045-1055. doi: 10.3233/JAD-220632. J Alzheimers Dis. 2022. PMID: 36189597 Free PMC article. Review.
A key factor or clue in this quest for an effective preventative and therapeutic treatment may lie in the contribution of hypertension to the disease. In this review, we explore the idea that photobiomodulation, the application of specific wavelengths of light onto body ti …
A key factor or clue in this quest for an effective preventative and therapeutic treatment may lie in the contribution of hypertension to th …
Cellular Signalling and Photobiomodulation in Chronic Wound Repair.
Leyane TS, Jere SW, Houreld NN. Leyane TS, et al. Int J Mol Sci. 2021 Oct 18;22(20):11223. doi: 10.3390/ijms222011223. Int J Mol Sci. 2021. PMID: 34681882 Free PMC article. Review.
Photobiomodulation (PBM) imparts therapeutically significant benefits in the healing of chronic wounds. ...
Photobiomodulation (PBM) imparts therapeutically significant benefits in the healing of chronic wounds. ...
Photobiomodulation and pain.
Keim RG. Keim RG. J Clin Orthod. 2020 Feb;54(2):69. J Clin Orthod. 2020. PMID: 32554914 No abstract available.
Low-intensity LASER and LED (photobiomodulation therapy) for pain control of the most common musculoskeletal conditions.
DE Oliveira MF, Johnson DS, Demchak T, Tomazoni SS, Leal-Junior EC. DE Oliveira MF, et al. Eur J Phys Rehabil Med. 2022 Apr;58(2):282-289. doi: 10.23736/S1973-9087.21.07236-1. Epub 2021 Dec 16. Eur J Phys Rehabil Med. 2022. PMID: 34913330 Free article.
Therefore, the purpose of this paper was to present the up-to-dated evidence about the effects of low-intensity LASER and LED (photobiomodulation therapy) on pain control of the most common musculoskeletal conditions. We observed that the photobiomodulation therapy …
Therefore, the purpose of this paper was to present the up-to-dated evidence about the effects of low-intensity LASER and LED (photobiomo
Photobiomodulation (low-level light therapy) and dry eye disease.
Markoulli M, Chandramohan N, Papas EB. Markoulli M, et al. Clin Exp Optom. 2021 Jul;104(5):561-566. doi: 10.1080/08164622.2021.1878866. Epub 2021 Feb 27. Clin Exp Optom. 2021. PMID: 33689636
A recent introduction to the in-office treatments available for meibomian gland dysfunction has been low-level light therapy, also known as photobiomodulation. The technique involves applying red, or near infra-red, radiation using low-power light sources and is suggested …
A recent introduction to the in-office treatments available for meibomian gland dysfunction has been low-level light therapy, also known as …
The effect of photobiomodulation on the brain during wakefulness and sleep.
Moro C, Valverde A, Dole M, Hoh Kam J, Hamilton C, Liebert A, Bicknell B, Benabid AL, Magistretti P, Mitrofanis J. Moro C, et al. Front Neurosci. 2022 Jul 28;16:942536. doi: 10.3389/fnins.2022.942536. eCollection 2022. Front Neurosci. 2022. PMID: 35968381 Free PMC article. Review.
These improvements are thought to arise principally from an impact of photobiomodulation on mitochondrial and non-mitochondrial mechanisms in a range of different cell types, including neurones. ...In this review, we consider the potential differential effects of photob
These improvements are thought to arise principally from an impact of photobiomodulation on mitochondrial and non-mitochondrial mecha …
Photobiomodulation and Oxidative/Nitrosative Stress.
Abrahamse H. Abrahamse H. Photobiomodul Photomed Laser Surg. 2021 Nov;39(11):685-686. doi: 10.1089/photob.2021.0084. Epub 2021 Oct 19. Photobiomodul Photomed Laser Surg. 2021. PMID: 34665042 No abstract available.
Photobiomodulation and Stem Cell Therapy for Temporomandibular Joint Disc Disorders.
Karic V, Chandran R, Abrahamse H. Karic V, et al. Photobiomodul Photomed Laser Surg. 2020 Jul;38(7):398-408. doi: 10.1089/photob.2019.4790. Epub 2020 Jun 2. Photobiomodul Photomed Laser Surg. 2020. PMID: 32486898 Review.
Objective: The objective of this review was to report updated information on photobiomodulation and stem cells, as an alternative treatment for the degenerative TMJ disc as a part of TMJ disorders. ...Conclusions: The need for a distinct shift of the research margin in thi …
Objective: The objective of this review was to report updated information on photobiomodulation and stem cells, as an alternative tre …
Photobiomodulation: The Clinical Applications of Low-Level Light Therapy.
Glass GE. Glass GE. Aesthet Surg J. 2021 May 18;41(6):723-738. doi: 10.1093/asj/sjab025. Aesthet Surg J. 2021. PMID: 33471046 Review.
Photobiomodulation is now highly commercialized with devices marketed directly to the consumer. ...OBJECTIVES: The aim of this article was to summarize the clinical evidence for photobiomodulation and discuss the regulatory framework for this therapy. ...
Photobiomodulation is now highly commercialized with devices marketed directly to the consumer. ...OBJECTIVES: The aim of this articl
Review of light parameters and photobiomodulation efficacy: dive into complexity.
Zein R, Selting W, Hamblin MR. Zein R, et al. J Biomed Opt. 2018 Dec;23(12):1-17. doi: 10.1117/1.JBO.23.12.120901. J Biomed Opt. 2018. PMID: 30550048 Free PMC article.
Photobiomodulation (PBM) therapy, previously known as low-level laser therapy, was discovered more than 50 years ago, yet there is still no agreement on the parameters and protocols for its clinical application. ...
Photobiomodulation (PBM) therapy, previously known as low-level laser therapy, was discovered more than 50 years ago, yet there is st
Photobiomodulation and myofascial temporomandibular disorder: Systematic review and meta-analysis followed by cost-effectiveness analysis.
Sobral AP, Sobral SS, Campos TM, Horliana AC, Fernandes KP, Bussadori SK, Motta LJ. Sobral AP, et al. J Clin Exp Dent. 2021 Jul 1;13(7):e724-e732. doi: 10.4317/jced.58084. eCollection 2021 Jul. J Clin Exp Dent. 2021. PMID: 34306537 Free PMC article. Review.
BACKGROUND: Photobiomodulation (PBM) is a non-invasive and non-pharmacological treatment, which, has shown beneficial results in the treatment of temporomandibular disorders (TMD) related pain. ...Key words:Temporomandibular disorder, Myofascial pain, Photobiomodulation
BACKGROUND: Photobiomodulation (PBM) is a non-invasive and non-pharmacological treatment, which, has shown beneficial results in the …
Current application and future directions of photobiomodulation in central nervous diseases.
Yang M, Yang Z, Wang P, Sun Z. Yang M, et al. Neural Regen Res. 2021 Jun;16(6):1177-1185. doi: 10.4103/1673-5374.300486. Neural Regen Res. 2021. PMID: 33269767 Free PMC article. Review.
Photobiomodulation using light in the red or near-infrared region is an innovative treatment strategy for a wide range of neurological and psychological conditions. Photobiomodulation can promote neurogenesis and elicit anti-apoptotic, anti-inflammatory and antioxid
Photobiomodulation using light in the red or near-infrared region is an innovative treatment strategy for a wide range of neurologica
Photobiomodulation Therapy and the Glymphatic System: Promising Applications for Augmenting the Brain Lymphatic Drainage System.
Salehpour F, Khademi M, Bragin DE, DiDuro JO. Salehpour F, et al. Int J Mol Sci. 2022 Mar 10;23(6):2975. doi: 10.3390/ijms23062975. Int J Mol Sci. 2022. PMID: 35328396 Free PMC article. Review.
An impaired brain glymphatic system can increase the incidence of neurovascular, neuroinflammatory, and neurodegenerative diseases. Photobiomodulation (PBM) therapy can serve as a non-invasive neuroprotective strategy for maintaining and optimizing effective brain waste cl …
An impaired brain glymphatic system can increase the incidence of neurovascular, neuroinflammatory, and neurodegenerative diseases. Photo
Impact of photobiomodulation on macrophages and their polarization during diabetic wound healing: a systematic review.
Rahmannia M, Amini A, Chien S, Bayat M. Rahmannia M, et al. Lasers Med Sci. 2022 Sep;37(7):2805-2815. doi: 10.1007/s10103-022-03581-5. Epub 2022 May 30. Lasers Med Sci. 2022. PMID: 35635648 Review.
This review aims to providing essential information and the current knowledge about the potential role of macrophages, especially their M2 subtypes in different diabetic wounds both in clinical and pre-clinical models under the influence of photobiomodulation (PBM). The lo …
This review aims to providing essential information and the current knowledge about the potential role of macrophages, especially their M2 s …
Photobiomodulation and space closure.
Priya P, Mishra S, Madhok S, Nongthombam H. Priya P, et al. Am J Orthod Dentofacial Orthop. 2022 Feb;161(2):e93. doi: 10.1016/j.ajodo.2021.09.013. Am J Orthod Dentofacial Orthop. 2022. PMID: 35094755 No abstract available.
Effects of Photobiomodulation on Oral Mucositis: Visualization and Analysis of Knowledge.
Melo WWP, Aragão WAB, Baia-da-Silva DC, Nascimento PC, Lima RR, de Souza-Rodrigues RD. Melo WWP, et al. Life (Basel). 2022 Nov 21;12(11):1940. doi: 10.3390/life12111940. Life (Basel). 2022. PMID: 36431074 Free PMC article. Review.
This review article mapped and analyzed the most cited articles on the association of photobiomodulation (PBM) with oral mucositis (OM) and the evolution of clinical protocols in the area. ...
This review article mapped and analyzed the most cited articles on the association of photobiomodulation (PBM) with oral mucositis (O …
Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review.
Muste JC, Russell MW, Singh RP. Muste JC, et al. Clin Ophthalmol. 2021 Sep 2;15:3709-3720. doi: 10.2147/OPTH.S272327. eCollection 2021. Clin Ophthalmol. 2021. PMID: 34511875 Free PMC article. Review.
PURPOSE: Photobiomodulation therapy (PBT) has emerged as a possible treatment for age-related macular degeneration (AMD) and diabetic retinopathy (DR). ...
PURPOSE: Photobiomodulation therapy (PBT) has emerged as a possible treatment for age-related macular degeneration (AMD) and diabetic …
Photobiomodulation Therapy in Burn Wound Healing: Systematic Review and Meta-Analysis of Preclinical Studies.
Deana NF, Alves N, Zaror C, Del Sol M, Bagnato VS. Deana NF, et al. Photobiomodul Photomed Laser Surg. 2021 Jul;39(7):439-452. doi: 10.1089/photob.2020.4972. Photobiomodul Photomed Laser Surg. 2021. PMID: 34264767
Background and objective: To determine the effectiveness of photobiomodulation therapy (PBMT) in the burn wound healing compared with the control or with the use of antibiotics, in animal models. ...
Background and objective: To determine the effectiveness of photobiomodulation therapy (PBMT) in the burn wound healing compared with …
Photobiomodulation in Endodontic, Restorative, and Prosthetic Dentistry: A Review of the Literature.
Vahdatinia F, Gholami L, Karkehabadi H, Fekrazad R. Vahdatinia F, et al. Photobiomodul Photomed Laser Surg. 2019 Dec;37(12):869-886. doi: 10.1089/photob.2019.4707. Photobiomodul Photomed Laser Surg. 2019. PMID: 31873065 Review.
Objective: To provide a review of the literature about the photobiomodulation therapy (PBMT) dental treatment protocols in endodontic, restorative, and prosthetic dentistry based on validated clinical studies published so far. ...Background data: The importance of using lo …
Objective: To provide a review of the literature about the photobiomodulation therapy (PBMT) dental treatment protocols in endodontic …
Photobiomodulation Therapy With Different Wavebands for Hair Loss: A Systematic Review and Meta-Analysis.
Zhang Y, Su J, Ma K, Fu X, Zhang C. Zhang Y, et al. Dermatol Surg. 2022 Jul 1;48(7):737-740. doi: 10.1097/DSS.0000000000003472. Epub 2022 Apr 25. Dermatol Surg. 2022. PMID: 35510860
BACKGROUND: Photobiomodulation is a promising therapy for hair loss with negligible side effects. However, the reported effects of photobiomodulation therapy for hair loss are inconsistent. OBJECTIVE: To assess the curative effect of photobiomodulation therap …
BACKGROUND: Photobiomodulation is a promising therapy for hair loss with negligible side effects. However, the reported effects of …
Photobiomodulation for the aging brain.
Cardoso FDS, Gonzalez-Lima F, Gomes da Silva S. Cardoso FDS, et al. Ageing Res Rev. 2021 Sep;70:101415. doi: 10.1016/j.arr.2021.101415. Epub 2021 Jul 26. Ageing Res Rev. 2021. PMID: 34325071 Review.
Among the non-pharmacological interventions studied for the treatment or prevention of age-related neurocognitive impairment, photobiomodulation (PBM) has gained prominence for its beneficial effects on brain functions relevant to aging brains. ...
Among the non-pharmacological interventions studied for the treatment or prevention of age-related neurocognitive impairment, photobiomod
The review of the light parameters and mechanisms of Photobiomodulation on melanoma cells.
Chen Z, Huang S, Liu M. Chen Z, et al. Photodermatol Photoimmunol Photomed. 2022 Jan;38(1):3-11. doi: 10.1111/phpp.12715. Epub 2021 Jul 7. Photodermatol Photoimmunol Photomed. 2022. PMID: 34181781 Review.
Photobiomodulation (PBM) uses low-intensity visible or near-infrared light to produce beneficial effects on cells or tissues, such as brain therapy, wound healing. ...
Photobiomodulation (PBM) uses low-intensity visible or near-infrared light to produce beneficial effects on cells or tissues, such as
The Signalling Effects of Photobiomodulation on Osteoblast Proliferation, Maturation and Differentiation: A Review.
Crous A, Abrahamse H. Crous A, et al. Stem Cell Rev Rep. 2021 Oct;17(5):1570-1589. doi: 10.1007/s12015-021-10142-w. Epub 2021 Mar 8. Stem Cell Rev Rep. 2021. PMID: 33686595 Review.
Over the past few decades, we have seen a significant improvement in awareness and techniques using photobiomodulation (PBM) to stimulate cell function. One of the applications of PBM is the promotion of osteoblast proliferation and maturation. ...
Over the past few decades, we have seen a significant improvement in awareness and techniques using photobiomodulation (PBM) to stimu …
Progress of phototherapy for osteosarcoma and application prospect of blue light photobiomodulation therapy.
Yang J, Fu Q, Jiang H, Li Y, Liu M. Yang J, et al. Front Oncol. 2022 Oct 13;12:1022973. doi: 10.3389/fonc.2022.1022973. eCollection 2022. Front Oncol. 2022. PMID: 36313662 Free PMC article. Review.
Phototherapy (PT), as a novel, non-invasive, and efficient antitumor therapeutic approach including photodynamic therapy (PDT), photothermal therapy (PTT), and photobiomodulation therapy (PBMT), has been widely applied in superficial skin tumor research and clinical treatm …
Phototherapy (PT), as a novel, non-invasive, and efficient antitumor therapeutic approach including photodynamic therapy (PDT), photothermal …
Photobiomodulation and implants: implications for dentistry.
Tang E, Arany P. Tang E, et al. J Periodontal Implant Sci. 2013 Dec;43(6):262-8. doi: 10.5051/jpis.2013.43.6.262. Epub 2013 Dec 31. J Periodontal Implant Sci. 2013. PMID: 24455438 Free PMC article. Review.
This latter aspect is the focus of this review, which outlines various studies of implants and laser therapy in animal models. The use of low level light therapy or photobiomodulation has demonstrated its efficacy in these studies. Besides more research studies to understa …
This latter aspect is the focus of this review, which outlines various studies of implants and laser therapy in animal models. The use of lo …
Shining light on the head: Photobiomodulation for brain disorders.
Hamblin MR. Hamblin MR. BBA Clin. 2016 Oct 1;6:113-124. doi: 10.1016/j.bbacli.2016.09.002. eCollection 2016 Dec. BBA Clin. 2016. PMID: 27752476 Free PMC article. Review.
Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has either been injured, is degenerating, or else is at risk of dying. ...Some workers have used lasers, but recently the introduction of inexpe
Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has
Photobiomodulation: How Many Sessions and How Often?
Tunér J. Tunér J. Photomed Laser Surg. 2018 Feb;36(2):59-60. doi: 10.1089/pho.2017.4387. Epub 2017 Dec 11. Photomed Laser Surg. 2018. PMID: 29227207 No abstract available.
Mechanisms of PhotoBioModulation (PBM) focused on oral mucositis prevention and treatment: a scoping review.
Courtois E, Bouleftour W, Guy JB, Louati S, Bensadoun RJ, Rodriguez-Lafrasse C, Magné N. Courtois E, et al. BMC Oral Health. 2021 Apr 29;21(1):220. doi: 10.1186/s12903-021-01574-4. BMC Oral Health. 2021. PMID: 33926421 Free PMC article. Review.
BACKGROUND: Oral mucositis (OM) is a severe complication cancer patients undergo when treated with chemoradiotherapy. Photobiomodulation (PBM) therapy also known as low-level laser therapy has been increasingly used for the treatment of such oral toxicity. The aim of this …
BACKGROUND: Oral mucositis (OM) is a severe complication cancer patients undergo when treated with chemoradiotherapy. Photobiomodulation
Regulatory Processes of the Canonical Wnt/β-Catenin Pathway and Photobiomodulation in Diabetic Wound Repair.
Jere SW, Houreld NN. Jere SW, et al. Int J Mol Sci. 2022 Apr 11;23(8):4210. doi: 10.3390/ijms23084210. Int J Mol Sci. 2022. PMID: 35457028 Free PMC article. Review.
Diabetic patients have a high risk of developing major impediments including wound contamination and limb amputation due to chronic, non-healing wounds. Photobiomodulation (PBM) involves the application of low-powered light at specific wavelengths to influence different bi …
Diabetic patients have a high risk of developing major impediments including wound contamination and limb amputation due to chronic, non-hea …
Association of photobiomodulation therapy and therapeutic exercises in relation to pain intensity and neck disability in individuals with chronic neck pain: a systematic review of randomized trials.
da Silva Júnior JEF, Vieira Dibai-Filho A, de Santana GN, da Silva ACB, Politti F, Aparecida Biasotto-Gonzalez D, de Paula Gomes CAF. da Silva Júnior JEF, et al. Lasers Med Sci. 2022 Apr;37(3):1427-1440. doi: 10.1007/s10103-021-03454-3. Epub 2021 Nov 12. Lasers Med Sci. 2022. PMID: 34767117 Review.
However, due to its complex range of causal factors and great diversity of signs and symptoms, other resources such as photobiomodulation therapy (PBMT) have been routinely used for the treatment of CNP. ...PubMed, Medline (via Ovid), Embase (via Ovid), Cinahl (via Ebsco), …
However, due to its complex range of causal factors and great diversity of signs and symptoms, other resources such as photobiomodulation
Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends.
Hong N. Hong N. Biomed Eng Lett. 2019 Jun 12;9(3):359-366. doi: 10.1007/s13534-019-00115-x. eCollection 2019 Aug. Biomed Eng Lett. 2019. PMID: 31456895 Free PMC article. Review.
Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. ...
Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. ..
Photobiomodulation for the management of hair loss.
Torres AE, Lim HW. Torres AE, et al. Photodermatol Photoimmunol Photomed. 2021 Mar;37(2):91-98. doi: 10.1111/phpp.12649. Epub 2021 Jan 13. Photodermatol Photoimmunol Photomed. 2021. PMID: 33377535 Review.
Photobiomodulation, otherwise known as low-level laser (or light) therapy, is an emerging modality for the management of hair loss. ...
Photobiomodulation, otherwise known as low-level laser (or light) therapy, is an emerging modality for the management of hair loss. .
Photobiomodulation and salivary glands: a systematic review.
Sousa AS, Silva JF, Pavesi VCS, Carvalho NA, Ribeiro-Júnior O, Varellis MLZ, Prates RA, Bussadori SK, Gonçalves MLL, Horliana ACRT, Deana AM. Sousa AS, et al. Lasers Med Sci. 2020 Jun;35(4):777-788. doi: 10.1007/s10103-019-02914-1. Epub 2019 Nov 25. Lasers Med Sci. 2020. PMID: 31768691
To date, there is no compilation of evidence-based information associating photobiomodulation effect and salivary glands. This systematic review aims to assess photobiomodulation effect of low intensity laser on salivary glands in the presence of systemic diseases. …
To date, there is no compilation of evidence-based information associating photobiomodulation effect and salivary glands. This system …
Photobiomodulation: lasers vs. light emitting diodes?
Heiskanen V, Hamblin MR. Heiskanen V, et al. Photochem Photobiol Sci. 2018 Aug 8;17(8):1003-1017. doi: 10.1039/c8pp90049c. Photochem Photobiol Sci. 2018. PMID: 30044464 Free PMC article.
Photobiomodulation (PBM) is a treatment method based on research findings showing that irradiation with certain wavelengths of red or near-infrared light has been shown to produce a range of physiological effects in cells, tissues, animals and humans. ...Advantages of LEDs
Photobiomodulation (PBM) is a treatment method based on research findings showing that irradiation with certain wavelengths of red or
Utilization of the 1064 nm Wavelength in Photobiomodulation: A Systematic Review and Meta-Analysis.
Penberthy WT, Vorwaller CE. Penberthy WT, et al. J Lasers Med Sci. 2021 Dec 28;12:e86. doi: 10.34172/jlms.2021.86. eCollection 2021. J Lasers Med Sci. 2021. PMID: 35155171 Free PMC article. Review.
Introduction: Photobiomodulation or low-level laser therapy (LLLT;<0.5 W) has been used as a non-invasive treatment for various medical indications. ...The 1064 nm wavelength as the longest wavelength is a relative newcomer in high-powered (>0.5 W) laser photobiom
Introduction: Photobiomodulation or low-level laser therapy (LLLT;<0.5 W) has been used as a non-invasive treatment for various me …
Efficacy of photobiomodulation in reducing pain and improving the quality of life in patients with idiopathic burning mouth syndrome. A systematic review and meta-analysis.
Camolesi GCV, Marichalar-Mendía X, Padín-Iruegas ME, Spanemberg JC, López-López J, Blanco-Carrión A, Gándara-Vila P, Gallas-Torreira M, Pérez-Sayáns M. Camolesi GCV, et al. Lasers Med Sci. 2022 Jun;37(4):2123-2133. doi: 10.1007/s10103-022-03518-y. Epub 2022 Feb 5. Lasers Med Sci. 2022. PMID: 35122543 Free PMC article. Review.
Treatment options include antidepressants, antipsychotics, anticonvulsants, analgesics, hormone replacement therapies and more recently photobiomodulation. This study aims to perform a systematic review with meta-analysis in order to determine the effect of photobiomodu
Treatment options include antidepressants, antipsychotics, anticonvulsants, analgesics, hormone replacement therapies and more recently p
Exploring the Use of Intracranial and Extracranial (Remote) Photobiomodulation Devices in Parkinson's Disease: A Comparison of Direct and Indirect Systemic Stimulations.
Johnstone DM, Hamilton C, Gordon LC, Moro C, Torres N, Nicklason F, Stone J, Benabid AL, Mitrofanis J. Johnstone DM, et al. J Alzheimers Dis. 2021;83(4):1399-1413. doi: 10.3233/JAD-210052. J Alzheimers Dis. 2021. PMID: 33843683 Review.
In recent times, photobiomodulation has been shown to be beneficial in animal models of Parkinson's disease, improving locomotive behavior and being neuroprotective. ...For indirect systemic stimulation, photobiomodulation could be applied to either the head and sca …
In recent times, photobiomodulation has been shown to be beneficial in animal models of Parkinson's disease, improving locomotive beh …
Photobiomodulation and photodynamic therapy-induced switching of autophagy and apoptosis in human dermal fibroblasts.
Pevna V, Horvath D, Wagnieres G, Huntosova V. Pevna V, et al. J Photochem Photobiol B. 2022 Sep;234:112539. doi: 10.1016/j.jphotobiol.2022.112539. Epub 2022 Aug 8. J Photochem Photobiol B. 2022. PMID: 35973285
Nowadays, photobiomodulation (PBM) in combination with chemotherapy or other therapeutic approaches is an attractive adjuvant modality for cancer treatment. ...
Nowadays, photobiomodulation (PBM) in combination with chemotherapy or other therapeutic approaches is an attractive adjuvant modalit …
How and why does photobiomodulation change brain activity?
Mitrofanis J, Henderson LA. Mitrofanis J, et al. Neural Regen Res. 2020 Dec;15(12):2243-2244. doi: 10.4103/1673-5374.284989. Neural Regen Res. 2020. PMID: 32594038 Free PMC article. No abstract available.
Sunlight and health: shifting the focus from vitamin D3 to photobiomodulation by red and near-infrared light.
Heiskanen V, Pfiffner M, Partonen T. Heiskanen V, et al. Ageing Res Rev. 2020 Aug;61:101089. doi: 10.1016/j.arr.2020.101089. Epub 2020 May 25. Ageing Res Rev. 2020. PMID: 32464190 Review.
Body irradiation with red and near-infrared light, usually termed as photobiomodulation (PBM), has demonstrated beneficial effects in animal models of chronic diseases. ...
Body irradiation with red and near-infrared light, usually termed as photobiomodulation (PBM), has demonstrated beneficial effects in …
Interferential current and photobiomodulation in knee osteoarthritis: A randomized, placebo-controlled, double-blind clinical trial.
Alqualo-Costa R, Rampazo ÉP, Thome GR, Perracini MR, Liebano RE. Alqualo-Costa R, et al. Clin Rehabil. 2021 Oct;35(10):1413-1427. doi: 10.1177/02692155211012004. Epub 2021 Apr 26. Clin Rehabil. 2021. PMID: 33896234 Clinical Trial.
SUBJECTS: A total of 184 patients with knee osteoarthritis were recruited and, of these, 168 were included and randomized into four groups with 42 each: interferential current, photobiomodulation, interferential current plus photobiomodulation or placebo groups. ... …
SUBJECTS: A total of 184 patients with knee osteoarthritis were recruited and, of these, 168 were included and randomized into four groups w …
Clinical practice guideline for the prevention of oral and oropharyngeal mucositis in pediatric cancer and hematopoietic stem cell transplant patients: 2021 update.
Patel P, Robinson PD, Baggott C, Gibson P, Ljungman G, Massey N, Ottaviani G, Phillips R, Revon-Rivière G, Treister N, White M, Cabral S, Dupuis L, Sung L. Patel P, et al. Eur J Cancer. 2021 Sep;154:92-101. doi: 10.1016/j.ejca.2021.05.013. Epub 2021 Jul 9. Eur J Cancer. 2021. PMID: 34252760 Free article. Review.
RESULTS: We included 107 unique studies of cryotherapy (22 RCTs and 4 pediatric studies); KGF (15 RCTs and 12 pediatric studies); photobiomodulation therapy (29 RCTs and 8 pediatric studies) and any intervention (31 pediatric RCTs). Effects on severe mucositis reduction fr …
RESULTS: We included 107 unique studies of cryotherapy (22 RCTs and 4 pediatric studies); KGF (15 RCTs and 12 pediatric studies); photobi
Rationale for 1068 nm Photobiomodulation Therapy (PBMT) as a Novel, Non-Invasive Treatment for COVID-19 and Other Coronaviruses: Roles of NO and Hsp70.
Kitchen LC, Berman M, Halper J, Chazot P. Kitchen LC, et al. Int J Mol Sci. 2022 May 7;23(9):5221. doi: 10.3390/ijms23095221. Int J Mol Sci. 2022. PMID: 35563611 Free PMC article. Review.
The purpose of this review is to explore the rationale for using photobiomodulation therapy (PBMT) of the particular wavelength 1068 nm as a therapy for COVID-19, investigating the cellular and molecular mechanisms involved. ...
The purpose of this review is to explore the rationale for using photobiomodulation therapy (PBMT) of the particular wavelength 1068 …
The JAK/STAT signaling pathway and photobiomodulation in chronic wound healing.
Jere SW, Abrahamse H, Houreld NN. Jere SW, et al. Cytokine Growth Factor Rev. 2017 Dec;38:73-79. doi: 10.1016/j.cytogfr.2017.10.001. Epub 2017 Oct 6. Cytokine Growth Factor Rev. 2017. PMID: 29032938 Review.
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway transmits extracellular signals to the nucleus for the transcription of genes involved in proliferation and differentiation, to name but a few. Photobiomodulation (PBM) is an emerging ar …
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway transmits extracellular signals to the nucleus for th …
Photobiomodulation-Activated Latent Transforming Growth Factor-β1: A Critical Clinical Therapeutic Pathway and an Endogenous Optogenetic Tool for Discovery.
Arany PR. Arany PR. Photobiomodul Photomed Laser Surg. 2022 Feb;40(2):136-147. doi: 10.1089/photob.2021.0109. Epub 2021 Dec 14. Photobiomodul Photomed Laser Surg. 2022. PMID: 34905400 Review.
This review outlines the evidence for selectively activating the endogenous, latent transforming growth factor (TGF)-beta1 with photobiomodulation (PBM) treatments. Background: Light treatments play a central role in current-directed energy therapeutics in medicine. ...
This review outlines the evidence for selectively activating the endogenous, latent transforming growth factor (TGF)-beta1 with photobiom
Transcranial photobiomodulation (laser) therapy for cognitive impairment: A review of molecular mechanisms and potential application to canine cognitive dysfunction (CCD).
Dewey CW, Brunke MW, Sakovitch K. Dewey CW, et al. Open Vet J. 2022 Mar-Apr;12(2):256-263. doi: 10.5455/OVJ.2022.v12.i2.14. Epub 2022 Apr 17. Open Vet J. 2022. PMID: 35603072 Free PMC article. Review.
CCD is considered a naturally occurring model of human AD. Transcranial photobiomodulation therapy (tPBMT), also known as transcranial laser therapy, entails delivering photons of near infrared to infrared light from the skin surface of the scalp to the underlying brain. . …
CCD is considered a naturally occurring model of human AD. Transcranial photobiomodulation therapy (tPBMT), also known as transcrania …
Histological and biochemical effects of preventive and therapeutic vascular photobiomodulation on rat muscle injury.
Lopez TCC, Malavazzi TCDS, Rodrigues MFSD, Bach EE, Silva DT, Hi EMB, França CM, Bussadori SK, Mesquita-Ferrari RA, Fernandes KPS. Lopez TCC, et al. J Biophotonics. 2022 May;15(5):e202100271. doi: 10.1002/jbio.202100271. Epub 2022 Jan 19. J Biophotonics. 2022. PMID: 34978386
The intravascular or transcutaneous application of photobiomodulation (PBM) over blood vessels (vascular photobiomodulation, VPBM) has been used for the treatment of inflammatory and chronic conditions with promising systemic results. ...
The intravascular or transcutaneous application of photobiomodulation (PBM) over blood vessels (vascular photobiomodulation, V …
Noninvasive red and near-infrared wavelength-induced photobiomodulation: promoting impaired cutaneous wound healing.
Yadav A, Gupta A. Yadav A, et al. Photodermatol Photoimmunol Photomed. 2017 Jan;33(1):4-13. doi: 10.1111/phpp.12282. Photodermatol Photoimmunol Photomed. 2017. PMID: 27943458 Review.
The innumerable intricacies associated with chronic wounds have made the development of new painless, noninvasive, biophysical therapeutic interventions as the focus of current biomedical research. Red and near-infrared light-induced photobiomodulation therapy appears to e …
The innumerable intricacies associated with chronic wounds have made the development of new painless, noninvasive, biophysical therapeutic i …
Interaction between Laser Light and Osteoblasts: Photobiomodulation as a Trend in the Management of Socket Bone Preservation-A Review.
Amaroli A, Colombo E, Zekiy A, Aicardi S, Benedicenti S, De Angelis N. Amaroli A, et al. Biology (Basel). 2020 Nov 23;9(11):409. doi: 10.3390/biology9110409. Biology (Basel). 2020. PMID: 33238412 Free PMC article. Review.
The literature shows that photons at the red and infrared wavelengths can interact with specific photoacceptors located within the cell. Through this mechanism, photobiomodulation (PBM) can modify cellular metabolism, by increasing mitochondrial ATP production. ...
The literature shows that photons at the red and infrared wavelengths can interact with specific photoacceptors located within the cell. Thr …
Photobiomodulation on trigeminal neuralgia: systematic review.
Ibarra AMC, Biasotto-Gonzalez DA, Kohatsu EYI, de Oliveira SSI, Bussadori SK, Tanganeli JPC. Ibarra AMC, et al. Lasers Med Sci. 2021 Jun;36(4):715-722. doi: 10.1007/s10103-020-03198-6. Epub 2020 Nov 20. Lasers Med Sci. 2021. PMID: 33219445
The available treatments are pharmacotherapy or surgery; however, both are susceptible to develop side effects. Photobiomodulation could be a promising alternative therapy for trigeminal neuralgia. ...Initially, 20 identified articles were collected varying between the yea …
The available treatments are pharmacotherapy or surgery; however, both are susceptible to develop side effects. Photobiomodulation co …
Effects of photobiomodulation and deep water running in patients with chronic non-specific low back pain: a randomized controlled trial.
Nardin DMK, Stocco MR, Aguiar AF, Machado FA, de Oliveira RG, Andraus RAC. Nardin DMK, et al. Lasers Med Sci. 2022 Jun;37(4):2135-2144. doi: 10.1007/s10103-021-03443-6. Epub 2022 Mar 4. Lasers Med Sci. 2022. PMID: 35246766 Clinical Trial.
Photobiomodulation therapy (PBM) is often used to treat musculoskeletal disorders such as chronic non-specific low back pain (NSCLBP) as it can have positive effects on biomarkers-creatine kinase (CK) and serum cortisol levels-related to stress caused by physical exercise,
Photobiomodulation therapy (PBM) is often used to treat musculoskeletal disorders such as chronic non-specific low back pain (NSCLBP)
Photobiomodulation at 830 nm Stimulates Migration, Survival and Proliferation of Fibroblast Cells.
Oyebode OA, Houreld NN. Oyebode OA, et al. Diabetes Metab Syndr Obes. 2022 Sep 21;15:2885-2900. doi: 10.2147/DMSO.S374649. eCollection 2022. Diabetes Metab Syndr Obes. 2022. PMID: 36172056 Free PMC article.
PURPOSE: Photobiomodulation (PBM) promotes diabetic wound healing by favoring cell survival and proliferation. ...
PURPOSE: Photobiomodulation (PBM) promotes diabetic wound healing by favoring cell survival and proliferation. ...
[State of art of photobiomodulation in the management of radiotherapy adverse events: Indications and level of evidence].
Klausner G, Bensadoun RJ, Champion A, Benzaquen D, Canova CH, Claren A, Mancuso V, Suhl J, Balard R, Troussier I. Klausner G, et al. Cancer Radiother. 2021 Oct;25(6-7):584-592. doi: 10.1016/j.canrad.2021.06.025. Epub 2021 Jul 13. Cancer Radiother. 2021. PMID: 34272181 Review. French.
PURPOSE: To evaluate the current and potential indications of photobiomodulation (PBM) and their level of evidence in the prevention or management of radiation therapy-related side effects. MATERIALS AND METHODS: The Embase, Medline/PubMed, Cochrane, EBSCO, Scopus, and LIL …
PURPOSE: To evaluate the current and potential indications of photobiomodulation (PBM) and their level of evidence in the prevention …
Narrative Review of Russian, Ukrainian and English-Language Publications Investigating the Effects of Photobiomodulation on Red Blood Cell Physiology.
Liebert A, Pang V, Caagby D, Arshinikova L, Kiat H. Liebert A, et al. Photobiomodul Photomed Laser Surg. 2022 Feb;40(2):98-111. doi: 10.1089/photob.2021.0069. Epub 2021 Dec 27. Photobiomodul Photomed Laser Surg. 2022. PMID: 34962147 Review.
Objective: The beneficial effects of photobiomodulation (PBM) on cellular function are well characterized, principally deriving from the absorption of red to near-infrared radiation by chromophores such as cytochrome-c-oxidase. ...
Objective: The beneficial effects of photobiomodulation (PBM) on cellular function are well characterized, principally deriving from …
Impact of photobiomodulation on external root resorption during orthodontic tooth movement in humans - A systematic review and meta-analysis.
Nayyer N, Tripathi T, Ganesh G, Rai P. Nayyer N, et al. J Oral Biol Craniofac Res. 2022 Jul-Aug;12(4):469-480. doi: 10.1016/j.jobcr.2022.05.014. Epub 2022 May 31. J Oral Biol Craniofac Res. 2022. PMID: 35692967 Free PMC article. Review.
BACKGROUND: Photobiomodulation has been gaining traction as a plausible therapy to control orthodontically induced root resorption. AIM: The aim of the present review was to systematically appraise randomized controlled trials conducted to study the influence of photobi
BACKGROUND: Photobiomodulation has been gaining traction as a plausible therapy to control orthodontically induced root resorption. A …
Efficacy of LED Photobiomodulation for Functional and Axonal Regeneration After Facial Nerve Section-Suture.
Er-Rouassi H, Benichou L, Lyoussi B, Vidal C. Er-Rouassi H, et al. Front Neurol. 2022 Feb 23;13:827218. doi: 10.3389/fneur.2022.827218. eCollection 2022. Front Neurol. 2022. PMID: 35280271 Free PMC article.
Facial nerve damage can lead to partial or total facial nerve palsy. Photobiomodulation has been reported to improve and accelerate functional recovery following peripheral nerve lesion, depending on the type of lesion and the light exposure parameters used. ...These findi …
Facial nerve damage can lead to partial or total facial nerve palsy. Photobiomodulation has been reported to improve and accelerate f …
Therapeutic photobiomodulation: nitric oxide and a novel function of mitochondrial cytochrome c oxidase.
Poyton RO, Ball KA. Poyton RO, et al. Discov Med. 2011 Feb;11(57):154-9. Discov Med. 2011. PMID: 21356170 Free article. Review.
Although early studies identified mitochondrial cytochrome c oxidase as an endogenous photoreceptor for photobiomodulation, the cellular and molecular mechanisms underlying photobiomodulation have not been clear. ...We also propose that the effectiveness of photo
Although early studies identified mitochondrial cytochrome c oxidase as an endogenous photoreceptor for photobiomodulation, the cellu …
Lights for epilepsy: can photobiomodulation reduce seizures and offer neuroprotection?
Torres-Martinez N, Chabardes S, Mitrofanis J. Torres-Martinez N, et al. Neural Regen Res. 2023 Jul;18(7):1423-1426. doi: 10.4103/1673-5374.360288. Neural Regen Res. 2023. PMID: 36571337 Free article. Review.
In this review, we consider the effectiveness of a potential new treatment for epilepsy, known as photobiomodulation, the use of red to near-infrared light on body tissues. Recent studies in animal models have shown that photobiomodulation reduces seizure-like activ …
In this review, we consider the effectiveness of a potential new treatment for epilepsy, known as photobiomodulation, the use of red …
Combined effects of photobiomodulation and curcumin on mast cells and wound strength in wound healing of streptozotocin-induced diabetes in rats.
Soleimani H, Amini A, Abdollahifar MA, Norouzian M, Kouhkheil R, Mostafavinia A, Ghoreishi SK, Bayat S, Chien S, Bayat M. Soleimani H, et al. Lasers Med Sci. 2021 Mar;36(2):375-386. doi: 10.1007/s10103-020-03053-8. Epub 2020 Jul 21. Lasers Med Sci. 2021. PMID: 32696423
Group 6 rats were treated with photobiomodulation and curcumin. We conducted stereological and tensiometric tests on days 4, 7, and 15 after treatment. The results indicated that photobiomodulation significantly improved wound strength in the diabetic rats and signi …
Group 6 rats were treated with photobiomodulation and curcumin. We conducted stereological and tensiometric tests on days 4, 7, and 1 …
Laser oromaxillofacial photobiomodulation therapy: molecular mechanisms, outcomes and considerations.
Fiani B, Jarrah R, Nathani KR. Fiani B, et al. Regen Med. 2022 Sep;17(9):611-615. doi: 10.2217/rme-2022-0091. Epub 2022 Jun 22. Regen Med. 2022. PMID: 35730260
Tweetable abstract Photobiomodulation therapy is largely characterized as a safe therapeutic model that can modulate the activity of inflammatory and immune biomarkers while facilitating a metabolic response that can regenerate damaged tissue....
Tweetable abstract Photobiomodulation therapy is largely characterized as a safe therapeutic model that can modulate the activity of …
The Rationale for Photobiomodulation Therapy of Vaginal Tissue for Treatment of Genitourinary Syndrome of Menopause: An Analysis of Its Mechanism of Action, and Current Clinical Outcomes.
Lanzafame RJ, de la Torre S, Leibaschoff GH. Lanzafame RJ, et al. Photobiomodul Photomed Laser Surg. 2019 Jul;37(7):395-407. doi: 10.1089/photob.2019.4618. Epub 2019 Jun 17. Photobiomodul Photomed Laser Surg. 2019. PMID: 31210575 Free PMC article. Review.
These have included procedures on both normal and neoplastic tissues, management of condylomata, endometriosis, and menometrorrhagia, and, more recently, a number of fractional laser devices have been applied for the management of genitourinary syndrome of menopause (GSM) and str …
These have included procedures on both normal and neoplastic tissues, management of condylomata, endometriosis, and menometrorrhagia, and, m …
Photobiomodulation therapy and antimicrobial photodynamic therapy for orofacial lesions in patients with COVID-19: A case series.
Teixeira IS, Leal FS, Tateno RY, Palma LF, Campos L. Teixeira IS, et al. Photodiagnosis Photodyn Ther. 2021 Jun;34:102281. doi: 10.1016/j.pdpdt.2021.102281. Epub 2021 Apr 1. Photodiagnosis Photodyn Ther. 2021. PMID: 33813018 Free PMC article.
Thus, the present study aimed to report a series of cases in which a combination of antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) was used for orofacial lesions in patients suffering from COVID-19. ...
Thus, the present study aimed to report a series of cases in which a combination of antimicrobial photodynamic therapy (aPDT) and photobi
Photobiomodulation reduces hippocampal apoptotic cell death and produces a Raman spectroscopic "signature".
Davies DJ, Hadis M, Di Pietro V, Lazzarino G, Forcione M, Harris G, Stevens AR, Soon WC, Goldberg Oppenheimer P, Milward M, Belli A, Palin WM. Davies DJ, et al. PLoS One. 2022 Mar 3;17(3):e0264533. doi: 10.1371/journal.pone.0264533. eCollection 2022. PLoS One. 2022. PMID: 35239693 Free PMC article.
This study investigates the effect of 660 nm photobiomodulation on organotypic slice cultured hippocampal tissue of rats, examining the effect on apoptotic cell loss. ...A significantly higher proportion of apoptotic cells 62.812.2% vs 48.613.7% (P<0.0001) per region we …
This study investigates the effect of 660 nm photobiomodulation on organotypic slice cultured hippocampal tissue of rats, examining t …
Photobiomodulation therapy as a high potential treatment modality for COVID-19.
Soheilifar S, Fathi H, Naghdi N. Soheilifar S, et al. Lasers Med Sci. 2021 Jul;36(5):935-938. doi: 10.1007/s10103-020-03206-9. Epub 2020 Nov 25. Lasers Med Sci. 2021. PMID: 33241526 Free PMC article. Review.
In severe cases, however, immune system impairment causes cytokine release syndrome which eventually leads to acute respiratory distress syndrome (ARDS). In recent years, photobiomodulation (PBM) has shown promising results in reducing acute pulmonary inflammation. ...
In severe cases, however, immune system impairment causes cytokine release syndrome which eventually leads to acute respiratory distress syn …
Retinal pigment epithelium in the pathogenesis of age-related macular degeneration and photobiomodulation as a potential therapy?
Ao J, Wood JP, Chidlow G, Gillies MC, Casson RJ. Ao J, et al. Clin Exp Ophthalmol. 2018 Aug;46(6):670-686. doi: 10.1111/ceo.13121. Epub 2018 Jan 12. Clin Exp Ophthalmol. 2018. PMID: 29205705 Review.
Dysfunction of the RPE has been associated with the pathogenesis of AMD in relation to increased oxidative stress, mitochondrial destabilization and complement dysregulation. Photobiomodulation or near infrared light therapy which refers to non-invasive irradiation of tiss …
Dysfunction of the RPE has been associated with the pathogenesis of AMD in relation to increased oxidative stress, mitochondrial destabiliza …
Vascular photobiomodulation increases muscle fiber diameter and improves the gait during compensatory hypertrophy of plantar muscle in rats.
Martinelli A, Andreo L, Dos Santos Malavazzi TC, Terena SML, da Cruz Tobelem D, Bussadori SK, Fernandes KPS, Mesquita-Ferrari RA. Martinelli A, et al. J Biophotonics. 2022 Dec;15(12):e202200192. doi: 10.1002/jbio.202200192. Epub 2022 Sep 11. J Biophotonics. 2022. PMID: 36054438
The local photobiomodulation (LPBM) has demonstrated positive effects during compensatory hypertrophy (CH) in skeletal muscle as a response to an overload. The aim was to compare the effects of the transcutaneous vascular photobiomodulation (VPBM) and the LPBM on mu …
The local photobiomodulation (LPBM) has demonstrated positive effects during compensatory hypertrophy (CH) in skeletal muscle as a re …
Efficacy of Photobiomodulation and Metformin on Diabetic Cell Line of Human Periodontal Ligament Stem Cells through Keap1/Nrf2/Ho-1 Pathway.
Mohamed Abdelgawad L, Abd El-Hamed MM, Sabry D, Abdelgwad M. Mohamed Abdelgawad L, et al. Rep Biochem Mol Biol. 2021 Apr;10(1):30-40. doi: 10.52547/rbmb.10.1.30. Rep Biochem Mol Biol. 2021. PMID: 34277866 Free PMC article.
Uncontrolled diabetes reflects great oral complications and affects human oral health. So, the present study aimed to assess the effects of photobiomodulation therapy (PBMT) and Metformin on proliferation and viability of human periodontal ligament stem cells (HPDLSCs) cul …
Uncontrolled diabetes reflects great oral complications and affects human oral health. So, the present study aimed to assess the effects of …
Photobiomodulation and the brain: a new paradigm.
Hennessy M, Hamblin MR. Hennessy M, et al. J Opt. 2017 Jan;19(1):013003. doi: 10.1088/2040-8986/19/1/013003. Epub 2016 Dec 14. J Opt. 2017. PMID: 28580093 Free PMC article.
Transcranial photobiomodulation (PBM) also known as low level laser therapy (tLLLT) relies on the use of red/NIR light to stimulate, preserve and regenerate cells and tissues. ...
Transcranial photobiomodulation (PBM) also known as low level laser therapy (tLLLT) relies on the use of red/NIR light to stimulate, …
Effects of photobiomodulation associated with orofacial myofactional therapy on temporomandibular joint dysfunction.
Alves GÂDS, Gondim YRDR, Lima JAS, Silva MAPD, Florêncio DSF, Almeida LNA, Silva HJD. Alves GÂDS, et al. Codas. 2021 Jun 4;33(6):e20200193. doi: 10.1590/2317-1782/20202020193. eCollection 2021. Codas. 2021. PMID: 34105614 Free article. Clinical Trial. English, Portuguese.
PURPOSE: To investigate the influence of photobiomodulation associated with orofacial myofunctional therapy (OMT) in patients with temporomandibular muscle disorders (TMD). ...The experimental group (EG) consisted of five women submitted to orofacial myofunctional therapy …
PURPOSE: To investigate the influence of photobiomodulation associated with orofacial myofunctional therapy (OMT) in patients with te …
Does laser photobiomodulation prevent hyposalivation in patients undergoing head and neck radiotherapy? A systematic review and meta-analysis of controlled trials.
Louzeiro GC, Teixeira DDS, Cherubini K, de Figueiredo MAZ, Salum FG. Louzeiro GC, et al. Crit Rev Oncol Hematol. 2020 Dec;156:103115. doi: 10.1016/j.critrevonc.2020.103115. Epub 2020 Oct 1. Crit Rev Oncol Hematol. 2020. PMID: 33039721 Review.
INTRODUCTION: Head and neck radiotherapy can cause hypofunction of the salivary glands. Many studies report that laser photobiomodulation (PBM) is able to minimize radiation-induced hyposalivation, yet there is no consensus about its effects. ...
INTRODUCTION: Head and neck radiotherapy can cause hypofunction of the salivary glands. Many studies report that laser photobiomodulation
Effectiveness of photobiomodulation in reducing pain and producing dental analgesia: a systematic review.
Kulkarni S, George R, Love R, Ranjitkar S. Kulkarni S, et al. Lasers Med Sci. 2022 Sep;37(7):3011-3019. doi: 10.1007/s10103-022-03590-4. Epub 2022 Jun 14. Lasers Med Sci. 2022. PMID: 35699807
PURPOSE: Photobiomodulation (PBM) is reported in many studies to produce dental analgesia without producing thermal damage to tissues. ...
PURPOSE: Photobiomodulation (PBM) is reported in many studies to produce dental analgesia without producing thermal damage to tissues …
A Narrative Review on the Use of Photobiomodulation Therapy for the Prevention and Management of Acute Radiodermatitis: Proposed Mechanisms, Current Clinical Outcomes, and Preliminary Guidance for Clinical Studies.
Robijns J, Lodewijckx J, Bensadoun RJ, Mebis J. Robijns J, et al. Photobiomodul Photomed Laser Surg. 2020 Jun;38(6):332-339. doi: 10.1089/photob.2019.4761. Epub 2020 May 27. Photobiomodul Photomed Laser Surg. 2020. PMID: 32460613 Review.
Objective: A narrative review of the available scientific evidence to identify the current proposals relating the use of photobiomodulation (PBM) to treat acute radiodermatitis (ARD), to guide future research. ...Results: Nine clinical trials that investigated the use of …
Objective: A narrative review of the available scientific evidence to identify the current proposals relating the use of photobiomodulati
Photobiomodulation therapy reduces acute pain and inflammation in mice.
Pigatto GR, Silva CS, Parizotto NA. Pigatto GR, et al. J Photochem Photobiol B. 2019 Jul;196:111513. doi: 10.1016/j.jphotobiol.2019.111513. Epub 2019 May 21. J Photochem Photobiol B. 2019. PMID: 31136885
Photobiomodulation (PBM) is a therapy suggested for the treatment of pain and inflammation. ...However, need further clarification regarding analgesic and anti-inflammatory effect of the photobiomodulation in preclinical studies....
Photobiomodulation (PBM) is a therapy suggested for the treatment of pain and inflammation. ...However, need further clarification re
Transcranial photobiomodulation changes topology, synchronizability, and complexity of resting state brain networks.
Ghaderi AH, Jahan A, Akrami F, Moghadam Salimi M. Ghaderi AH, et al. J Neural Eng. 2021 May 10;18(4). doi: 10.1088/1741-2552/abf97c. J Neural Eng. 2021. PMID: 33873167
Objective. Transcranial photobiomodulation (tPBM) is a recently proposed non-invasive brain stimulation approach with various effects on the nervous system from the cells to the whole brain networks. ...
Objective. Transcranial photobiomodulation (tPBM) is a recently proposed non-invasive brain stimulation approach with various effects …
Photobiomodulation therapy and NMES improve muscle strength and jumping performance in young volleyball athletes: a randomized controlled trial study in Brazil.
da Cunha RA, Pinfildi CE, de Castro Pochini A, Cohen M. da Cunha RA, et al. Lasers Med Sci. 2020 Apr;35(3):621-631. doi: 10.1007/s10103-019-02858-6. Epub 2019 Aug 11. Lasers Med Sci. 2020. PMID: 31402432 Clinical Trial.
The athletes in the photobiomodulation therapy group were submitted to photobiomodulation therapy (850 nm, continuous, energy density 0.8 J/cm(2), radiant energy per point 6 J, total radiant energy 36 J) before undergoing strength and plyometric training. ...This st …
The athletes in the photobiomodulation therapy group were submitted to photobiomodulation therapy (850 nm, continuous, energy …
Impact of preconditioned diabetic stem cells and photobiomodulation on quantity and degranulation of mast cells in a delayed healing wound simulation in type one diabetic rats.
Ahmadi H, Bayat M, Amini A, Mostafavinia A, Ebrahimpour-Malekshah R, Gazor R, Asadi R, Gachkar L, Rezaei F, Shafikhani SH, Ghoreishi SK, Chien S. Ahmadi H, et al. Lasers Med Sci. 2022 Apr;37(3):1593-1604. doi: 10.1007/s10103-021-03408-9. Epub 2021 Sep 2. Lasers Med Sci. 2022. PMID: 34476655
In G3, diabetic ADS were engrafted into the wound, and the wound was exposed to photobiomodulation (890 nm, 890 10 nm, 80 Hz, 0.2 J/cm(2)) in vivo. In G4, preconditioned diabetic ADS with photobiomodulation (630 and 810 nm; each 3 times with 1.2 J/cm(2)) in vitro we …
In G3, diabetic ADS were engrafted into the wound, and the wound was exposed to photobiomodulation (890 nm, 890 10 nm, 80 Hz, 0.2 J/c …
Brain Photobiomodulation-Preliminary Results from Regional Cerebral Oximetry and Thermal Imaging.
Litscher G. Litscher G. Medicines (Basel). 2019 Jan 16;6(1):11. doi: 10.3390/medicines6010011. Medicines (Basel). 2019. PMID: 30654508 Free PMC article.
A new piece of equipment for LED (light emitting diode) brain photobiomodulation is introduced. Preliminary results from regional cerebral oxygen saturation and from thermography are shown before, during and after stimulation. ...
A new piece of equipment for LED (light emitting diode) brain photobiomodulation is introduced. Preliminary results from regional cer …
Blue-LED-Light Photobiomodulation of Inflammatory Responses and New Tissue Formation in Mouse-Skin Wounds.
Magni G, Tatini F, Siena G, Pavone FS, Alfieri D, Cicchi R, Rossi M, Murciano N, Paroli G, Vannucci C, Sistri G, Pini R, Bacci S, Rossi F. Magni G, et al. Life (Basel). 2022 Oct 9;12(10):1564. doi: 10.3390/life12101564. Life (Basel). 2022. PMID: 36295000 Free PMC article.
This study aims to investigate blue-light (410-430 nm) photobiomodulation used in a murine wound model within six days post-treatment. ...Finally, collagen deposition and morphology in the treated wounds appear more similar to unwounded skin. Conclusions: Blue-light pho
This study aims to investigate blue-light (410-430 nm) photobiomodulation used in a murine wound model within six days post-treatment …
Does photobiomodulation change the synthesis and secretion of angiogenic proteins by different pulp cell lineages?
Vitor LLR, Prado MTO, Lourenço Neto N, Oliveira RC, Sakai VT, Santos CF, Dionísio TJ, Rios D, Cruvinel T, Machado MAAM, Oliveira TM. Vitor LLR, et al. J Photochem Photobiol B. 2020 Jan;203:111738. doi: 10.1016/j.jphotobiol.2019.111738. Epub 2019 Dec 12. J Photochem Photobiol B. 2020. PMID: 31954290
HPF (control group) and SHED were plated, let to adhere, and put on serum starvation to synchronize the cell cycles prior to photobiomodulation. Then, both cell lineages were irradiated with 660-nm laser according to the following groups: 2.5 and 3.7 J/cm(2). ...Photobi
HPF (control group) and SHED were plated, let to adhere, and put on serum starvation to synchronize the cell cycles prior to photobiomodu
Antimicrobial photodynamic and photobiomodulation adjuvant therapies for the treatment of perianal abscess.
Campos TA, Penido L, Junior ALR, Laginha PA, Campos L, Palma LF. Campos TA, et al. Photodiagnosis Photodyn Ther. 2021 Sep;35:102437. doi: 10.1016/j.pdpdt.2021.102437. Epub 2021 Jul 11. Photodiagnosis Photodyn Ther. 2021. PMID: 34260992
Considering the debate on the role of postoperative antibiotic therapy for patients with perianal abscess and the significant discomfort caused by the infection, the present study aimed to report a clinical case in which antimicrobial photodynamic therapy (aPDT) and photobiomo
Considering the debate on the role of postoperative antibiotic therapy for patients with perianal abscess and the significant discomfort cau …
Photobiomodulation therapy upregulates the growth kinetics and multilineage differentiation potential of human dental pulp stem cells-an in vitro Study.
Dawoud LE, Hegazy EM, Galhom RA, Youssef MM. Dawoud LE, et al. Lasers Med Sci. 2022 Apr;37(3):1993-2003. doi: 10.1007/s10103-021-03461-4. Epub 2021 Nov 17. Lasers Med Sci. 2022. PMID: 34787763
Cells of the irradiated groups showed enhanced differentiation towards osteogenic and chondrogenic lineages as revealed by histochemical staining using alizarin red and alcian blue stains. Photobiomodulation is an emerging promising element of tissue engineering triad besi …
Cells of the irradiated groups showed enhanced differentiation towards osteogenic and chondrogenic lineages as revealed by histochemical sta …
Photobiomodulation Improves the Inflammatory Response and Intracellular Signaling Proteins Linked to Vascular Function and Cell Survival in the Brain of Aged Rats.
Dos Santos Cardoso F, Mansur FCB, Araújo BHS, Gonzalez-Lima F, Gomes da Silva S. Dos Santos Cardoso F, et al. Mol Neurobiol. 2022 Jan;59(1):420-428. doi: 10.1007/s12035-021-02606-4. Epub 2021 Oct 27. Mol Neurobiol. 2022. PMID: 34708330
Photobiomodulation is a non-pharmacological tool widely used to reduce inflammation in many tissues. ...In addition, the laser treatment increased the hippocampal expression of p70S6K, STAT3, and p38 of aged rats. Taken together, our data indicate that transcranial phot
Photobiomodulation is a non-pharmacological tool widely used to reduce inflammation in many tissues. ...In addition, the laser treatm
Photobiomodulation Therapy Affects the Elastic Modulus, Cytoskeletal Rearrangement and Migration Capability of Human Osteosarcoma Cells.
Barati Shoorche A, Mohammadkarim A, Jadidi M, Bahraminasab M. Barati Shoorche A, et al. Lasers Med Sci. 2022 Sep;37(7):2855-2863. doi: 10.1007/s10103-022-03554-8. Epub 2022 Apr 8. Lasers Med Sci. 2022. PMID: 35394552
Photobiomodulation (PBM) therapy utilizes low-power lasers to modulate the viability of living human cells and leads to changes in proliferation, differentiation, adhesion and gene expression, even though the rearrangement of cytoskeleton was not previously studied. ...Wit
Photobiomodulation (PBM) therapy utilizes low-power lasers to modulate the viability of living human cells and leads to changes in pr
Impact of photobiomodulation for oral mucositis on body weight and BMI of patients with head and neck cancer.
de Sousa Melo A, Andrade CL, de Lima Dantas JB, Medrado ARAP, Martins GB, Lima HR, Carrera M. de Sousa Melo A, et al. Support Care Cancer. 2022 Jun;30(6):4897-4904. doi: 10.1007/s00520-022-06899-6. Epub 2022 Feb 15. Support Care Cancer. 2022. PMID: 35169872
PURPOSE: To evaluate the impact of photobiomodulation for oral mucositis on body weight and body mass index (BMI) in head and neck cancer patients. METHODS: Patients were separated into two groups: photobiomodulation (PBM) (n = 17) and SHAM (n = 19). Participants as …
PURPOSE: To evaluate the impact of photobiomodulation for oral mucositis on body weight and body mass index (BMI) in head and neck ca …
Does Photobiomodulation Therapy Enhance Maximal Muscle Strength and Muscle Recovery?
Tsuk S, Lev YH, Fox O, Carasso R, Dunsky A. Tsuk S, et al. J Hum Kinet. 2020 Jul 21;73:135-144. doi: 10.2478/hukin-2019-0138. eCollection 2020 Jul. J Hum Kinet. 2020. PMID: 32774545 Free PMC article.
Photobiomodulation has been shown to improve tissue and cell functions. ...Applying photobiomodulation for 10 min immediately before exercise did not improve muscle function or muscle recovery after fatigue....
Photobiomodulation has been shown to improve tissue and cell functions. ...Applying photobiomodulation for 10 min immediately
Photobiomodulation Therapy for Dementia: A Systematic Review of Pre-Clinical and Clinical Studies.
Salehpour F, Khademi M, Hamblin MR. Salehpour F, et al. J Alzheimers Dis. 2021;83(4):1431-1452. doi: 10.3233/JAD-210029. J Alzheimers Dis. 2021. PMID: 33935090
BACKGROUND: Photobiomodulation (PBM) involves the use of red and/or near-infrared light from lasers or LEDs to improve a wide range of medical disorders. ...
BACKGROUND: Photobiomodulation (PBM) involves the use of red and/or near-infrared light from lasers or LEDs to improve a wide range o …
The efficacy and safety of the combination of photobiomodulation therapy and pulsed electromagnetic field therapy on androgenetic alopecia.
Choi MS, Park BC. Choi MS, et al. J Cosmet Dermatol. 2022 Nov 8. doi: 10.1111/jocd.15490. Online ahead of print. J Cosmet Dermatol. 2022. PMID: 36345917
BACKGROUND: Photobiomodulation therapy (PBMT) appears to be safe and effective for hair loss. ...
BACKGROUND: Photobiomodulation therapy (PBMT) appears to be safe and effective for hair loss. ...
Photobiomodulation and Antimicrobial Photodynamic Therapy for Oral Ulcers in a Patient With Thrombocytopenia Following Bone Marrow Transplantation.
Campos L, Campanhã D, Tateno RY, Palma LF. Campos L, et al. J Lasers Med Sci. 2022 Apr 21;13:e17. doi: 10.34172/jlms.2022.17. eCollection 2022. J Lasers Med Sci. 2022. PMID: 35996489 Free PMC article.
The lesions were managed using a combination of phototherapies (photobiomodulation and antimicrobial photodynamic therapies), totalizing 4 laser sessions. ...
The lesions were managed using a combination of phototherapies (photobiomodulation and antimicrobial photodynamic therapies), totaliz …
Investigation of the effects of therapeutic ultrasound or photobiomodulation and the role of spinal glial cells in osteoarthritis-induced nociception in mice.
Malta I, Moraes T, Elisei L, Novaes R, Galdino G. Malta I, et al. Lasers Med Sci. 2022 Apr;37(3):1687-1698. doi: 10.1007/s10103-021-03418-7. Epub 2021 Sep 20. Lasers Med Sci. 2022. PMID: 34542770
Thus, this study aimed to investigate the effects of ultrasound and photobiomodulation on the symptoms and evaluate the participation of spinal glia in osteoarthritis-induced nociception in mice. ...Additionally, the mice received chronic ultrasound or photobiomodulatio
Thus, this study aimed to investigate the effects of ultrasound and photobiomodulation on the symptoms and evaluate the participation …
Photobiomodulation therapy and transcutaneous electrical nerve stimulation on chronic neck pain patients: Study protocol clinical trial (SPIRIT Compliant).
Rampazo ÉP, de Andrade ALM, da Silva VR, Back CGN, Liebano RE. Rampazo ÉP, et al. Medicine (Baltimore). 2020 Feb;99(8):e19191. doi: 10.1097/MD.0000000000019191. Medicine (Baltimore). 2020. PMID: 32080103 Free PMC article. Clinical Trial.
One hundred and forty-four patients with chronic neck pain will be randomized into 4 groups: active photobiomodulation therapy with active electrical stimulation, active photobiomodulation therapy, active electrical stimulation, or placebo treatment. ...DISCUSSION: …
One hundred and forty-four patients with chronic neck pain will be randomized into 4 groups: active photobiomodulation therapy with a …
The Comparison of The Efficacy of Photobiomodulation and Ultrasound in the Treatment of Chronic Non-specific Neck Pain: A Randomized Single-Blind Controlled Trial.
Kenareh R, Mirmohammadi SJ, Khatibi A, Shamsi F, Mehrparvar AH. Kenareh R, et al. J Lasers Med Sci. 2021 May 17;12:e20. doi: 10.34172/jlms.2021.20. eCollection 2021. J Lasers Med Sci. 2021. PMID: 34733743 Free PMC article.

The VAS score and NDI scores decreased after both kinds of interventions, and the effect of photobiomodulation was significantly higher than physiotherapy (P < 0.001). Both treatment modalities significantly affect different aspects of chronic neck pain assessed by NDPS

The VAS score and NDI scores decreased after both kinds of interventions, and the effect of photobiomodulation was significantly high …
Absorption of monochromatic and narrow band radiation in the visible and near IR by both mitochondrial and non-mitochondrial photoacceptors results in photobiomodulation.
Passarella S, Karu T. Passarella S, et al. J Photochem Photobiol B. 2014 Nov;140:344-58. doi: 10.1016/j.jphotobiol.2014.07.021. Epub 2014 Aug 21. J Photochem Photobiol B. 2014. PMID: 25226343 Review.
Accordingly it is generally accepted that mitochondria are crucial in cell photobiomodulation; however a variety of biomolecules themselves proved to be targets of light irradiation. ...All together the reported investigations show that the elucidation of the mechanism of …
Accordingly it is generally accepted that mitochondria are crucial in cell photobiomodulation; however a variety of biomolecules them …
Impact of photobiomodulation and low-intensity pulsed ultrasound adjunctive interventions on orthodontic treatment duration during clear aligner therapy.
Al-Dboush R, Esfahani AN, El-Bialy T. Al-Dboush R, et al. Angle Orthod. 2021 Sep 1;91(5):619-625. doi: 10.2319/112420-956.1. Angle Orthod. 2021. PMID: 34407180 Free PMC article.
OBJECTIVE: To assess the efficiency of low-intensity pulsed ultrasound (LIPUS) and photobiomodulation (PBM) interventions in accelerating orthodontic tooth movement during clear aligner therapy (CAT). ...
OBJECTIVE: To assess the efficiency of low-intensity pulsed ultrasound (LIPUS) and photobiomodulation (PBM) interventions in accelera …
An exploration of the use of photobiomodulation for management of oral mucositis in children and young people undergoing cancer treatment in the UK.
Heggie C, Gray-Burrows KA, Day PF, Phillips B. Heggie C, et al. Support Care Cancer. 2022 Dec;30(12):10179-10190. doi: 10.1007/s00520-022-07450-3. Epub 2022 Nov 9. Support Care Cancer. 2022. PMID: 36350380 Free PMC article.
The current use of photobiomodulation within the UK, and the barriers and facilitators to implementation is unknown. ...Quantitative data underwent descriptive statistics. Barriers and facilitators to the implementation of photobiomodulation were analysed using the …
The current use of photobiomodulation within the UK, and the barriers and facilitators to implementation is unknown. ...Quantitative …
Improved Spatial Memory And Neuroinflammatory Profile Changes in Aged Rats Submitted to Photobiomodulation Therapy.
Cardoso FDS, de Souza Oliveira Tavares C, Araujo BHS, Mansur F, Lopes-Martins RÁB, Gomes da Silva S. Cardoso FDS, et al. Cell Mol Neurobiol. 2022 Aug;42(6):1875-1886. doi: 10.1007/s10571-021-01069-4. Epub 2021 Mar 11. Cell Mol Neurobiol. 2022. PMID: 33704604
Recent evidences have shown the therapeutic potential of transcranial photobiomodulation on traumatic brain injury and Alzheimer's disease. Despite the promising benefits in the brain, little is known about the laser's effects in the absence of pathological conditions. ... …
Recent evidences have shown the therapeutic potential of transcranial photobiomodulation on traumatic brain injury and Alzheimer's di …
Combined application of chondroitinase ABC and photobiomodulation with low-intensity laser on the anal sphincter repair in rabbit.
Sarveazad A, Yari A, Babaei-Ghazani A, Mokhtare M, Bahardoust M, Asar S, Shamseddin J, Yousefifard M, Babahajian A. Sarveazad A, et al. BMC Gastroenterol. 2021 Dec 15;21(1):473. doi: 10.1186/s12876-021-02047-2. BMC Gastroenterol. 2021. PMID: 34911454 Free PMC article.
BACKGROUND: Photobiomodulation with low-intensity laser (LIL) and chondroitinase ABC (ChABC) can repair damaged muscle tissue, so the aim of this study was to investigate the effect of co-administration of these two factors on anal sphincter repair in rabbits. ...VEGFA (p …
BACKGROUND: Photobiomodulation with low-intensity laser (LIL) and chondroitinase ABC (ChABC) can repair damaged muscle tissue, so the …
Low-intensity photobiomodulation at 632.8 nm increases tgfβ3, col2a1, and sox9 gene expression in rat bone marrow mesenchymal stem cells in vitro.
Bozhokin MS, Vcherashnii DB, Yastrebov SG, Beilinson LL, Zherebtsova JV, Khotin MG. Bozhokin MS, et al. Lasers Med Sci. 2022 Feb;37(1):435-441. doi: 10.1007/s10103-021-03279-0. Epub 2021 Feb 26. Lasers Med Sci. 2022. PMID: 33634352
At the present time, some data are available about the 632.8 nm low-intensity laser photobiomodulation positive effect on the cartilage tissue proliferation. ...The main aim of this work was to assess the low-intensity photobiomodulation effect on chondrogenesis. In …
At the present time, some data are available about the 632.8 nm low-intensity laser photobiomodulation positive effect on the cartila …
Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression.
Kerppers FK, Dos Santos KMMG, Cordeiro MER, da Silva Pereira MC, Barbosa D, Pezzini AA, Cunha LF, Fonseca M, Bragnholo K, Salgado ASI, Kerppers II. Kerppers FK, et al. Lasers Med Sci. 2020 Dec;35(9):1945-1954. doi: 10.1007/s10103-020-02983-7. Epub 2020 Mar 7. Lasers Med Sci. 2020. PMID: 32144511 Clinical Trial.
Transcranial photobiomodulation is an innovative method for the stimulation of neural activity which consists of the exposure of neural tissue to low-level light irradiance. ...The objective was to analyze the effects of transcranial photobiomodulation using 945-nm …
Transcranial photobiomodulation is an innovative method for the stimulation of neural activity which consists of the exposure of neur …
Photobiomodulation devices for hair regrowth and wound healing: a therapy full of promise but a literature full of confusion.
Mignon C, Botchkareva NV, Uzunbajakava NE, Tobin DJ. Mignon C, et al. Exp Dermatol. 2016 Oct;25(10):745-9. doi: 10.1111/exd.13035. Epub 2016 Jul 13. Exp Dermatol. 2016. PMID: 27095546 Review.
Photobiomodulation is reported to positively influence hair regrowth, wound healing, skin rejuvenation and psoriasis. ...To derive parameters for optimal clinical efficacy of photobiomodulation, we recommend a more rational approach to underpin clinical studies, wit
Photobiomodulation is reported to positively influence hair regrowth, wound healing, skin rejuvenation and psoriasis. ...To derive pa
The effects of photobiomodulation therapy on inflammatory mediators, immune infiltration, and angiogenesis in a mouse model of rosacea.
Wu S, Su Y, Wang L, Sun B, Jiang X. Wu S, et al. Ann Transl Med. 2022 Aug;10(15):831. doi: 10.21037/atm-22-3204. Ann Transl Med. 2022. PMID: 36035005 Free PMC article.
BACKGROUND: Rosacea is a chronic skin disorder with increasing prevalence and challenging management. Photobiomodulation therapy (PBMT) may be a promising adjuvant treatment for rosacea. ...
BACKGROUND: Rosacea is a chronic skin disorder with increasing prevalence and challenging management. Photobiomodulation therapy (PBM …
Photobiomodulation at Different Wavelengths Boosts Mitochondrial Redox Metabolism and Hemoglobin Oxygenation: Lasers vs. Light-Emitting Diodes In Vivo.
Pruitt T, Carter C, Wang X, Wu A, Liu H. Pruitt T, et al. Metabolites. 2022 Jan 23;12(2):103. doi: 10.3390/metabo12020103. Metabolites. 2022. PMID: 35208178 Free PMC article.
Our group previously examined 8 min photobiomodulation (PBM) by 1064 nm laser on the human forearm in vivo to determine its significant effects on vascular hemodynamics and cytochrome c oxidase redox activity. ...
Our group previously examined 8 min photobiomodulation (PBM) by 1064 nm laser on the human forearm in vivo to determine its significa …
Photobiomodulation Modulates Interleukin-10 and Interferon Gamma Production by Mononuclear Cells from Healthy Donors and Persons with Multiple Sclerosis.
Tolentino M, Cho CC, Lyons JA. Tolentino M, et al. Photobiomodul Photomed Laser Surg. 2022 Apr;40(4):234-244. doi: 10.1089/photob.2021.0169. Photobiomodul Photomed Laser Surg. 2022. PMID: 35452300
Background: Photobiomodulation (PBM) therapy was previously shown to reduce the clinical severity of disease and modulated pro- and anti-inflammatory cytokines in an animal model of multiple sclerosis (MS). ...
Background: Photobiomodulation (PBM) therapy was previously shown to reduce the clinical severity of disease and modulated pro- and a …
Assessment of Healing and Pain Response at Mandibular Third Molar Extraction Sites with and Without Pre- and PostOperative Photobiomodulation at Red and Near-Infrared Wavelengths: A Clinical Study.
Gururaj SB, Shankar SM, Parveen F, Chidambar CK, Bhushan K, Prabhudev CM. Gururaj SB, et al. J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S470-S474. doi: 10.4103/jpbs.jpbs_675_21. Epub 2022 Jul 13. J Pharm Bioallied Sci. 2022. PMID: 36110661 Free PMC article.
BACKGROUND: Photobiomodulation (PBM), formerly known as low-level laser therapy, has been successfully used for its anti-inflammatory and analgesic properties in postoperative care. ...
BACKGROUND: Photobiomodulation (PBM), formerly known as low-level laser therapy, has been successfully used for its anti-inflammatory …
Photobiomodulation via multiple-wavelength radiations.
Lima AMCT, da Silva Sergio LP, de Souza da Fonseca A. Lima AMCT, et al. Lasers Med Sci. 2020 Mar;35(2):307-316. doi: 10.1007/s10103-019-02879-1. Epub 2019 Sep 16. Lasers Med Sci. 2020. PMID: 31523781 Review.
Photobiomodulation via a combination of different radiations can produce different effects on biological tissues, such as cell proliferation and differentiation, when compared to those produced via a single radiation. The present study aims to conduct a review of the liter
Photobiomodulation via a combination of different radiations can produce different effects on biological tissues, such as cell prolif
Effects and parameters of the photobiomodulation in experimental models of third-degree burn: systematic review.
Ocon CA, Dos Santos SA, Caires JR, de Oliveira MFD, Serra AJ, Leal-Junior EC, de Carvalho PTC. Ocon CA, et al. Lasers Med Sci. 2019 Apr;34(3):637-648. doi: 10.1007/s10103-018-2633-3. Epub 2018 Sep 18. Lasers Med Sci. 2019. PMID: 30229346
EMBASE, PubMed, and CINAHL databases were searched for studies published between January 2003 and January 2018 on the topics of photobiomodulation therapy and third-degree burns. Any study that assessed the effects of photobiomodulation therapy in animal models of t …
EMBASE, PubMed, and CINAHL databases were searched for studies published between January 2003 and January 2018 on the topics of photobiom
Photobiomodulation therapy and endodontic treatment of teeth with apical periodontitis using 940-nm diode laser. Report of two cases.
Rubio F, Wienecke F, Arnabat-Domínguez J, Betancourt P. Rubio F, et al. J Clin Exp Dent. 2022 Mar 1;14(3):e298-e302. doi: 10.4317/jced.59058. eCollection 2022 Mar. J Clin Exp Dent. 2022. PMID: 35317289 Free PMC article.
BACKGROUND: Diode laser (DL) can be used in endodontics both for its bactericidal effect inside the root canal system (RCS) and for photobiomodulation therapy (PBMT) to accelerate the repair of periradicular bone tissue. ...In both cases reported, bone neoformation were fo …
BACKGROUND: Diode laser (DL) can be used in endodontics both for its bactericidal effect inside the root canal system (RCS) and for photo
Photobiomodulation for Tendinopathy: A Review of Preclinical Studies.
Alzyoud JAM, Omoush SA, Al-Qtaitat A. Alzyoud JAM, et al. Photobiomodul Photomed Laser Surg. 2022 Jun;40(6):370-377. doi: 10.1089/photob.2021.0192. Epub 2022 May 27. Photobiomodul Photomed Laser Surg. 2022. PMID: 35639100 Review.
Moreover, it is recommended to prove efficacy using at least two evaluation methods and apply Photobiomodulation as a combined varying energy/wavelength protocol (several energies with several wavelengths). Clinical relevance: Establishing a proof of concept for Photobi
Moreover, it is recommended to prove efficacy using at least two evaluation methods and apply Photobiomodulation as a combined varyin …
Stimulatory responses in α- and β-cells by near-infrared (810 nm) photobiomodulation.
Liebman C, Loya S, Lawrence M, Bashoo N, Cho M. Liebman C, et al. J Biophotonics. 2022 Mar;15(3):e202100257. doi: 10.1002/jbio.202100257. Epub 2021 Dec 6. J Biophotonics. 2022. PMID: 34837336
Attenuated insulin release in the first phase is typically associated with abnormal beta-cells. While near-infrared photobiomodulation (PBM) demonstrates potential for multiple therapeutic applications, photostimulatory effects on alpha- and beta-cells remain to be further …
Attenuated insulin release in the first phase is typically associated with abnormal beta-cells. While near-infrared photobiomodulation
Optimization of the Duration and Dose of Photobiomodulation Therapy (660 nm Laser) for Spinal Cord Injury in Rats.
Neshasteh-Riz A, Ramezani F, Kookli K, Moghaddas Fazeli S, Motamed A, Nasirinezhad F, Janzadeh A, Hamblin MR, Asadi M. Neshasteh-Riz A, et al. Photobiomodul Photomed Laser Surg. 2022 Jul;40(7):488-498. doi: 10.1089/photob.2022.0012. Photobiomodul Photomed Laser Surg. 2022. PMID: 35867119
Objective: Spinal cord injury (SCI) causes motor deficits, urinary incontinence, and neuropathic pain. This study was designed to optimize a photobiomodulation therapy (PBMT) protocol using a continuous wave (CW) 660 nm laser in rats with SCI. ...No improvement was seen in …
Objective: Spinal cord injury (SCI) causes motor deficits, urinary incontinence, and neuropathic pain. This study was designed to optimize a …
Photobiomodulation Therapy Does Not Attenuate Fatigue and Muscle Damage in Judo Athletes: A Randomized, Triple-Blind, Placebo-Controlled Trial.
Orssatto LBDR, Detanico D, Kons RL, Sakugawa RL, da Silva JN Jr, Diefenthaeler F. Orssatto LBDR, et al. Front Physiol. 2019 Jun 26;10:811. doi: 10.3389/fphys.2019.00811. eCollection 2019. Front Physiol. 2019. PMID: 31297066 Free PMC article.
Our objective was to investigate the effects of photobiomodulation therapy on fatigue and muscle damage in judo athletes. ...No differences were observed between photobiomodulation therapy and placebo at any time points for any variables (p > 0.05), indicating no …
Our objective was to investigate the effects of photobiomodulation therapy on fatigue and muscle damage in judo athletes. ...No diffe …
A Role for Photobiomodulation in the Prevention of Myocardial Ischemic Reperfusion Injury: A Systematic Review and Potential Molecular Mechanisms.
Liebert A, Krause A, Goonetilleke N, Bicknell B, Kiat H. Liebert A, et al. Sci Rep. 2017 Feb 9;7:42386. doi: 10.1038/srep42386. Sci Rep. 2017. PMID: 28181487 Free PMC article. Review.
A growing body of evidence supporting the use of photobiomodulation in myocardial infarct models has implicated multiple molecular interactions. A systematic review was conducted to identify the strength of the evidence for the therapeutic effect of photobiomodulation
A growing body of evidence supporting the use of photobiomodulation in myocardial infarct models has implicated multiple molecular in …
Adherence of head and neck cancer patients to laser photobiomodulation in a public health service: Pilot study.
da Costa JDR, de Lima Dantas JB, Martins GB, Carrera M, de Almeida Reis SR, Medrado ARAP. da Costa JDR, et al. Complement Ther Med. 2021 May;58:102687. doi: 10.1016/j.ctim.2021.102687. Epub 2021 Feb 18. Complement Ther Med. 2021. PMID: 33610725 Free article.

A total of fifteen patients (50%) missed one or more laser photobiomodulation sessions. A positive association was found between patients who missed at least two laser photobiomodulation sessions with the development of OM degrees III (p < 0.05). CONCLUSIONS: The

A total of fifteen patients (50%) missed one or more laser photobiomodulation sessions. A positive association was found between pati …
Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.
Wang X, Zhang Z, Zhu Z, Liang Z, Zuo X, Ju C, Song Z, Li X, Hu X, Wang Z. Wang X, et al. Front Neurosci. 2021 Nov 2;15:768262. doi: 10.3389/fnins.2021.768262. eCollection 2021. Front Neurosci. 2021. PMID: 34795557 Free PMC article.
After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive phenotypes according to their different functions: neurotoxic (A1) astrocytes and neuroprotective (A2) astrocytes. Our previous studies proved that photobiomodulation (PBM) can promo …
After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive phenotypes according to their different functions …
Photobiomodulation in acceleration of orthodontic tooth movement: A systematic review and meta analysis.
AlShahrani I, Togoo RA, Hosmani J, Alhaizaey A. AlShahrani I, et al. Complement Ther Med. 2019 Dec;47:102220. doi: 10.1016/j.ctim.2019.102220. Epub 2019 Oct 16. Complement Ther Med. 2019. PMID: 31780019
BACKGROUND: Photobiomodulation therapy, a non invasive method with no adverse effects, has been used to accelerate tooth movement in orthodontia. ...OBJECTIVES: We decided to undertake a systematic review to eliminate this inconsistency by quantifying the literature studie …
BACKGROUND: Photobiomodulation therapy, a non invasive method with no adverse effects, has been used to accelerate tooth movement in …
Photobiomodulation Therapy on Physiological and Performance Parameters During Running Tests: Dose-Response Effects.
Dellagrana RA, Rossato M, Sakugawa RL, Baroni BM, Diefenthaeler F. Dellagrana RA, et al. J Strength Cond Res. 2018 Oct;32(10):2807-2815. doi: 10.1519/JSC.0000000000002488. J Strength Cond Res. 2018. PMID: 29481447 Clinical Trial.
Dellagrana, RA, Rossato, M, Sakugawa, RL, Baroni, BM, and Diefenthaeler, F. Photobiomodulation therapy on physiological and performance parameters during running tests: Dose-response effects. J Strength Cond Res 32(10): 2807-2815, 2018-This study was aimed at verifying eff …
Dellagrana, RA, Rossato, M, Sakugawa, RL, Baroni, BM, and Diefenthaeler, F. Photobiomodulation therapy on physiological and performan …
Effect of Photobiomodulation on Secretion of IL-6 and IL-8 by Human Gingival Fibroblasts In Vitro.
Harorli OT, Hatipoglu M, Erin N. Harorli OT, et al. Photobiomodul Photomed Laser Surg. 2019 Aug;37(8):457-464. doi: 10.1089/photob.2018.4589. Photobiomodul Photomed Laser Surg. 2019. PMID: 31390315
Objective: The aim of this study was to evaluate the effects of 940-nm diode laser irradiation on proinflammatory cytokine secretions [interleukin (IL)-6 and IL-8] by human gingival fibroblasts in vitro. Background: Photobiomodulation has been routinely used in many dental …
Objective: The aim of this study was to evaluate the effects of 940-nm diode laser irradiation on proinflammatory cytokine secretions [inter …
Effect of Photobiomodulation on Periodontal Ligament Cells Under Inflamed and Nutrient-Deficient Conditions Simulating Damaged Cells of Avulsed Teeth: An In Vitro Study.
Wang G, Yuan L, Zhang L, Qin M, Wang Y. Wang G, et al. Photobiomodul Photomed Laser Surg. 2021 Nov;39(11):696-704. doi: 10.1089/photob.2021.0045. Epub 2021 Oct 27. Photobiomodul Photomed Laser Surg. 2021. PMID: 34705541
Background: The prognosis of replanted teeth is depended on the vitality of periodontal ligament cells residual on the root surface. Photobiomodulation has photobiological effects that can promote cell vitality. ...Conclusions: The photobiomodulation of 808 nm laser …
Background: The prognosis of replanted teeth is depended on the vitality of periodontal ligament cells residual on the root surface. Phot
Photobiomodulation and the expression of genes related to the JAK/STAT signalling pathway in wounded and diabetic wounded cells.
Jere SW, Houreld NN, Abrahamse H. Jere SW, et al. J Photochem Photobiol B. 2020 Mar;204:111791. doi: 10.1016/j.jphotobiol.2020.111791. Epub 2020 Jan 17. J Photochem Photobiol B. 2020. PMID: 31981991
Photobiomodulation therapy (PBMT) is a curative technique that uses low intensity light to relegate pain and inflammation, and accelerate tissue repair. At a molecular level, the effects of photobiomodulation (PBM) are not fully established. The present study aimed
Photobiomodulation therapy (PBMT) is a curative technique that uses low intensity light to relegate pain and inflammation, and accele
The Effects of Photobiomodulation on Leukocyte and Platelet-Rich Fibrin as Barrier Membrane on Bone Regeneration: An Experimental Animal Study.
Surmeli Baran S, Temmerman A, Salimov F, Ucak Turer O, Sapmaz T, Haytac MC, Ozcan M. Surmeli Baran S, et al. Photobiomodul Photomed Laser Surg. 2021 Apr;39(4):245-253. doi: 10.1089/photob.2020.4943. Epub 2021 Jan 11. Photobiomodul Photomed Laser Surg. 2021. PMID: 33434103
Objective: To compare the effects of leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation therapy (PBMT)-applied L-PRF (PBMT/L-PRF) as barrier membranes on new bone formation (BV/TV) for the treatment of critical-sized bone defects. ...
Objective: To compare the effects of leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation therapy (PBMT)-applied L-PRF ( …
Laser-photobiomodulation on titanium implant bone healing in rat model: comparison between 660- and 808-nm wavelength.
da Fonseca GAMD, Cavalcanti MFXB, de Souza Maior JD, da Silva Pereira J, Pinto LA, Matias M, Frigo L. da Fonseca GAMD, et al. Lasers Med Sci. 2022 Jun;37(4):2179-2184. doi: 10.1007/s10103-021-03481-0. Epub 2022 Jan 14. Lasers Med Sci. 2022. PMID: 35028766
Laser-photobiomodulation (L-PBM) has been widely studied and its biomodulatory effects have been established on irradiated cells, increasing viability and proliferation and on damaged tissues. In addition, L-PBM may reduce and modulate the inflammatory process. The effect …
Laser-photobiomodulation (L-PBM) has been widely studied and its biomodulatory effects have been established on irradiated cells, inc …
Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains.
Cardoso FDS, Barrett DW, Wade Z, Gomes da Silva S, Gonzalez-Lima F. Cardoso FDS, et al. Front Neurosci. 2022 Mar 18;16:818005. doi: 10.3389/fnins.2022.818005. eCollection 2022. Front Neurosci. 2022. PMID: 35368252 Free PMC article.
CCO is also the major intracellular acceptor of photons in the light wavelengths used for photobiomodulation (PBM). Brain function is critically dependent on oxygen consumption by CCO for ATP production. ...
CCO is also the major intracellular acceptor of photons in the light wavelengths used for photobiomodulation (PBM). Brain function is …
Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis.
Cassano P, Petrie SR, Hamblin MR, Henderson TA, Iosifescu DV. Cassano P, et al. Neurophotonics. 2016 Jul;3(3):031404. doi: 10.1117/1.NPh.3.3.031404. Epub 2016 Mar 4. Neurophotonics. 2016. PMID: 26989758 Free PMC article. Review.
We examined the use of near-infrared and red radiation (photobiomodulation, PBM) for treating major depressive disorder (MDD). While still experimental, preliminary data on the use of PBM for brain disorders are promising. ...
We examined the use of near-infrared and red radiation (photobiomodulation, PBM) for treating major depressive disorder (MDD). While …
Effects of ozonated olive oil and photobiomodulation using diode laser on gingival depigmented wound: A randomized clinical study.
Tualzik T, Chopra R, Gupta SJ, Sharma N, Khare M, Gulati L. Tualzik T, et al. J Indian Soc Periodontol. 2021 Sep-Oct;25(5):422-426. doi: 10.4103/jisp.jisp_655_20. Epub 2021 Aug 30. J Indian Soc Periodontol. 2021. PMID: 34667386 Free PMC article.
OBJECTIVE: Photobiomodulation (PBM) using diode laser is regarded an effective modality for the repair of tissues and control of pain. ...
OBJECTIVE: Photobiomodulation (PBM) using diode laser is regarded an effective modality for the repair of tissues and control of pain …
Exploring the Effect of Combined Transcranial and Intra-Oral Photobiomodulation Therapy Over a Four-Week Period on Physical and Cognitive Outcome Measures for People with Parkinson's Disease: A Randomized Double-Blind Placebo-Controlled Pilot Study.
Bullock-Saxton J, Lehn A, Laakso EL. Bullock-Saxton J, et al. J Alzheimers Dis. 2021;83(4):1499-1512. doi: 10.3233/JAD-210170. J Alzheimers Dis. 2021. PMID: 34092640 Clinical Trial.
BACKGROUND: Neuroprotection against Parkinson's disease degeneration by photobiomodulation has been reported in animal models but no true placebo-controlled human studies have been published. OBJECTIVE: To understand if photobiomodulation therapy can produce clinica …
BACKGROUND: Neuroprotection against Parkinson's disease degeneration by photobiomodulation has been reported in animal models but no …
Effects of Photobiomodulation on Degranulation and Number of Mast Cells and Wound Strength in Skin Wound Healing of Streptozotocin-Induced Diabetic Rats.
Bagheri M, Amini A, Abdollahifar MA, Ghoreishi SK, Piryaei A, Pouriran R, Chien S, Dadras S, Rezaei F, Bayat M. Bagheri M, et al. Photomed Laser Surg. 2018 Aug;36(8):415-423. doi: 10.1089/pho.2018.4453. Epub 2018 Jul 6. Photomed Laser Surg. 2018. PMID: 30004319
The first group was considered as the control (placebo) group, the second group received CM, the third group received photobiomodulation, and the fourth group received photobiomodulation+CM. ...Histologically, photobiomodulation+CM, CM, and photobiomodulat
The first group was considered as the control (placebo) group, the second group received CM, the third group received photobiomodulation
Treatment of Kleine-Levin Syndrome With Intranasal Photobiomodulation and Methylene Blue.
Hamper M, Cassano P, Lombard J. Hamper M, et al. Cureus. 2021 Oct 8;13(10):e18596. doi: 10.7759/cureus.18596. eCollection 2021 Oct. Cureus. 2021. PMID: 34659921 Free PMC article.
The parents of the patient agreed to attempt a trial of intranasal photobiomodulation (i-PBM) with red light, in combination with methylene blue (MB). ...
The parents of the patient agreed to attempt a trial of intranasal photobiomodulation (i-PBM) with red light, in combination with met …
Management of Medication-Related Osteonecrosis of the Jaw (MRONJ) Using Leukocyte- and Platelet-Rich Fibrin (L-PRF) and Photobiomodulation: A Retrospective Study.
Tenore G, Zimbalatti A, Rocchetti F, Graniero F, Gaglioti D, Mohsen A, Caputo M, Lollobrigida M, Lamazza L, De Biase A, Barbato E, Romeo U. Tenore G, et al. J Clin Med. 2020 Oct 29;9(11):3505. doi: 10.3390/jcm9113505. J Clin Med. 2020. PMID: 33138266 Free PMC article.
G1 was treated with antibiotic therapy, surgery, leukocyte- and platelet-rich fibrin (L-PRF), and photobiomodulation; G2 was treated with antibiotic therapy and surgery; G3 was treated with antibiotic therapy and photobiomodulation. ...CONCLUSIONS: Our results show …
G1 was treated with antibiotic therapy, surgery, leukocyte- and platelet-rich fibrin (L-PRF), and photobiomodulation; G2 was treated …
Neuronal differentiation potential of primary and immortalized adipose stem cells by photobiomodulation.
George S, Hamblin MR, Abrahamse H. George S, et al. J Photochem Photobiol B. 2022 May;230:112445. doi: 10.1016/j.jphotobiol.2022.112445. Epub 2022 Apr 9. J Photochem Photobiol B. 2022. PMID: 35453038
On the contrary, the use of genetically modified (immortalized) ASCs has the benefit of accessibility by surpassing ethical concerns and ease for propagation as a continuous cell culture. Photobiomodulation (PBM) is a therapeutic modality with laser or light, which is wide …
On the contrary, the use of genetically modified (immortalized) ASCs has the benefit of accessibility by surpassing ethical concerns and eas …
Photobiomodulation effects on mRNA levels from genomic and chromosome stabilization genes in injured muscle.
da Silva Neto Trajano LA, Trajano ETL, da Silva Sergio LP, Teixeira AF, Mencalha AL, Stumbo AC, de Souza da Fonseca A. da Silva Neto Trajano LA, et al. Lasers Med Sci. 2018 Sep;33(7):1513-1519. doi: 10.1007/s10103-018-2510-0. Epub 2018 Apr 26. Lasers Med Sci. 2018. PMID: 29696446
A great number of athletes have relapsed in muscle injuries not being treated properly. Photobiomodulation therapy is an inexpensive and safe technique with many benefits in muscle injury treatment. ...In conclusion, photobiomodulation alters mRNA relative levels fr …
A great number of athletes have relapsed in muscle injuries not being treated properly. Photobiomodulation therapy is an inexpensive …
Photobiomodulation with a 645 nm Diode Laser of Saos-2 Cells and Platelet-Rich Plasma: The Potential for a New Mechanism of Action.
Ghidini G, Mori D, Pulcini S, Vescovi P, Sala R. Ghidini G, et al. Photobiomodul Photomed Laser Surg. 2021 Feb;39(2):86-93. doi: 10.1089/photob.2020.4839. Epub 2021 Jan 20. Photobiomodul Photomed Laser Surg. 2021. PMID: 33471588
Objective: The main focus of this in vitro study was to highlight possible differences between outcomes of photobiomodulation performed in the presence or absence of growth factors derived from platelet-rich plasma. Background: Photobiomodulation has garnered increa …
Objective: The main focus of this in vitro study was to highlight possible differences between outcomes of photobiomodulation perform …
Photobiomodulation promotes angiogenesis in wound healing through stimulating the nuclear translocation of VEGFR2 and STAT3.
Zhang G, Yi L, Wang C, Yang P, Zhang J, Wang J, Lu C, Zhang X, Liu Y. Zhang G, et al. J Photochem Photobiol B. 2022 Dec;237:112573. doi: 10.1016/j.jphotobiol.2022.112573. Epub 2022 Sep 22. J Photochem Photobiol B. 2022. PMID: 36403534
In recent years, Photobiomodulation (PBM) has gained prevalence as a kind of physical therapy for wound healing, however, concerning specific cellular mechanisms induced by PBM remains uncertain. ...
In recent years, Photobiomodulation (PBM) has gained prevalence as a kind of physical therapy for wound healing, however, concerning …
Comparative analysis of the light parameters of red and near-infrared diode lasers to induce photobiomodulation on fibroblasts and keratinocytes: An in vitro study.
Topaloglu N, Özdemir M, Çevik ZBY. Topaloglu N, et al. Photodermatol Photoimmunol Photomed. 2021 May;37(3):253-262. doi: 10.1111/phpp.12645. Epub 2020 Dec 23. Photodermatol Photoimmunol Photomed. 2021. PMID: 33332651
BACKGROUND: Photobiomodulation (PBM) depends on the use of non-ionizing light energy to trigger photochemical changes, particularly in light-sensitive mitochondrial structures. ...
BACKGROUND: Photobiomodulation (PBM) depends on the use of non-ionizing light energy to trigger photochemical changes, particularly i …
The Effect of Photobiomodulation on Distraction Osteogenesis.
Sarmadi S, Tanbakuchi B, Hesam Arefi A, Chiniforush N. Sarmadi S, et al. J Lasers Med Sci. 2019 Fall;10(4):330-337. doi: 10.15171/jlms.2019.53. Epub 2019 Oct 1. J Lasers Med Sci. 2019. PMID: 31875127 Free PMC article. Review.
New bone gradually forms and fills the gap, and the bone height increases as such. Photobiomodulation (PBM) or low-level laser therapy (LLLT) enhances the formation of soft and hard tissue such as bone and can, therefore, accelerate the process of DO and shorten the durati …
New bone gradually forms and fills the gap, and the bone height increases as such. Photobiomodulation (PBM) or low-level laser therap …
LED and laser photobiomodulation in the prevention and treatment of oral mucositis: experimental study in hamsters.
Freire Mdo R, Freitas R, Colombo F, Valença A, Marques AM, Sarmento VA. Freire Mdo R, et al. Clin Oral Investig. 2014 Apr;18(3):1005-13. doi: 10.1007/s00784-013-1058-4. Epub 2013 Aug 15. Clin Oral Investig. 2014. PMID: 23949015
RESULTS: The results indicated loss of body mass, xerostomia, and alopecia in the animals subjected to Che and the healing of OM to different degrees after the photobiomodulation treatment. Histologically, the positive control and experimental groups showed inflammation, p …
RESULTS: The results indicated loss of body mass, xerostomia, and alopecia in the animals subjected to Che and the healing of OM to differen …
Photobiomodulation therapy and vitamin C on longevity of cell sheets of human dental pulp stem cells.
Pedroni ACF, Diniz IMA, Abe GL, Moreira MS, Sipert CR, Marques MM. Pedroni ACF, et al. J Cell Physiol. 2018 Oct;233(10):7026-7035. doi: 10.1002/jcp.26626. Epub 2018 May 10. J Cell Physiol. 2018. PMID: 29744863
Photobiomodulation therapy (PBMT) can improve processes relevant to tissue regeneration, such as survival, proliferation, migration, and differentiation of cells, including stem cells. ...
Photobiomodulation therapy (PBMT) can improve processes relevant to tissue regeneration, such as survival, proliferation, migration,
Combination of Group Singular Value Decomposition and eLORETA Identifies Human EEG Networks and Responses to Transcranial Photobiomodulation.
Wang X, Wanniarachchi H, Wu A, Liu H. Wang X, et al. Front Hum Neurosci. 2022 May 10;16:853909. doi: 10.3389/fnhum.2022.853909. eCollection 2022. Front Hum Neurosci. 2022. PMID: 35620152 Free PMC article.
Transcranial Photobiomodulation (tPBM) has demonstrated its ability to alter electrophysiological activity in the human brain. ...
Transcranial Photobiomodulation (tPBM) has demonstrated its ability to alter electrophysiological activity in the human brain. ...
Photobiomodulation in Neuroscience: A Summary of Personal Experience.
Rochkind S. Rochkind S. Photomed Laser Surg. 2017 Nov;35(11):604-615. doi: 10.1089/pho.2017.4381. Photomed Laser Surg. 2017. PMID: 29099679 Review.
OBJECTIVE: This review summarizes personal experience with laser photobiomodulation and its potentials for the treatment of peripheral and central nerve system injuries. ...Additional well-designed clinical studies are needed to evaluate the effectiveness and role of laser …
OBJECTIVE: This review summarizes personal experience with laser photobiomodulation and its potentials for the treatment of periphera …
Tumor radiosensitization by photobiomodulation.
de Faria CMG, Barrera-Patiño CP, Santana JPP, da Silva de Avó LR, Bagnato VS. de Faria CMG, et al. J Photochem Photobiol B. 2021 Dec;225:112349. doi: 10.1016/j.jphotobiol.2021.112349. Epub 2021 Nov 1. J Photochem Photobiol B. 2021. PMID: 34742031
PURPOSE: To investigate the safety of photobiomodulation therapy (PBM) in tumors and its potential as a radiosensitizer when combined with radiotherapy. ...
PURPOSE: To investigate the safety of photobiomodulation therapy (PBM) in tumors and its potential as a radiosensitizer when combined …
Metabolic Connectivity and Hemodynamic-Metabolic Coherence of Human Prefrontal Cortex at Rest and Post Photobiomodulation Assessed by Dual-Channel Broadband NIRS.
Wang X, Ma LC, Shahdadian S, Wu A, Truong NCD, Liu H. Wang X, et al. Metabolites. 2022 Jan 5;12(1):42. doi: 10.3390/metabo12010042. Metabolites. 2022. PMID: 35050164 Free PMC article.
In this study, we introduced a novel measurement-plus-analysis framework for the non-invasive quantification of prefrontal ISO by (1) taking dual-channel broadband near infrared spectroscopy (bbNIRS) measurements from 12 healthy humans during a 6-min rest and 4-min post transcran …
In this study, we introduced a novel measurement-plus-analysis framework for the non-invasive quantification of prefrontal ISO by (1) taking …
Stimulation and homogenization of the protoporphyrin IX endogenous production by photobiomodulation to increase the potency of photodynamic therapy.
Joniová J, Kazemiraad C, Gerelli E, Wagnières G. Joniová J, et al. J Photochem Photobiol B. 2021 Dec;225:112347. doi: 10.1016/j.jphotobiol.2021.112347. Epub 2021 Oct 28. J Photochem Photobiol B. 2021. PMID: 34736068
Although routinely used in the clinics, the stimulated production of PpIX is often insufficient and/or heterogeneous within the lesions, thereby limiting the PDT performances. Since photobiomodulation, which is based on the illumination of the tissues with sub-thermal radi …
Although routinely used in the clinics, the stimulated production of PpIX is often insufficient and/or heterogeneous within the lesions, the …
Synergistic Effects of Photobiomodulation Therapy with Combined Wavelength on Diabetic Wound Healing In Vitro and In Vivo.
Cai W, Hamushan M, Zhang Y, Xu Z, Ren Z, Du J, Ju J, Cheng P, Tan M, Han P. Cai W, et al. Photobiomodul Photomed Laser Surg. 2022 Jan;40(1):13-24. doi: 10.1089/photob.2021.0068. Epub 2021 Dec 23. Photobiomodul Photomed Laser Surg. 2022. PMID: 34941461
Objective: The difficulty in chronic diabetic wound healing remains the focus of clinical research. Photobiomodulation therapy (PBMT) with different wavelengths could exert different effects on wound healing, but the effects of combined red and blue light (BL) remained unc …
Objective: The difficulty in chronic diabetic wound healing remains the focus of clinical research. Photobiomodulation therapy (PBMT) …
Histologic and Biomechanical Evaluation of Osseointegrated Miniscrew Implants Treated with Ozone Therapy and Photobiomodulation at Different Loading Times.
Yücesoy T, Seker ED, Cenkcı E, Yay A, Alkan A. Yücesoy T, et al. Int J Oral Maxillofac Implants. 2019 Nov/Dec;34(6):1337-1345. doi: 10.11607/jomi.7601. Int J Oral Maxillofac Implants. 2019. PMID: 31711076
RESULTS: According to the results of the Infinite Focus Microscopy, the ozone therapy group revealed significantly higher scores than the control group and photobiomodulation group at the 4-week loading time, whereas the photobiomodulation and ozone therapy groups r …
RESULTS: According to the results of the Infinite Focus Microscopy, the ozone therapy group revealed significantly higher scores than the co …
Photobiomodulation for the treatment of retinal diseases: a review.
Geneva II. Geneva II. Int J Ophthalmol. 2016 Jan 18;9(1):145-52. doi: 10.18240/ijo.2016.01.24. eCollection 2016. Int J Ophthalmol. 2016. PMID: 26949625 Free PMC article. Review.
Photobiomodulation (PBM), also known as low level laser therapy, has recently risen to the attention of the ophthalmology community as a promising new approach to treat a variety of retinal conditions including age-related macular degeneration, retinopathy of prematurity,
Photobiomodulation (PBM), also known as low level laser therapy, has recently risen to the attention of the ophthalmology community a
Chronic Supraspinatus Tendonitis Pain: An Integrative Approach for Treatment with Cross-Fiber Massage, Electroacupuncture, Far-Infrared Heat, and Photobiomodulation.
Liu S. Liu S. Med Acupunct. 2022 Aug 1;34(4):251-255. doi: 10.1089/acu.2022.0041. Epub 2022 Aug 17. Med Acupunct. 2022. PMID: 36051417
MATERIALS AND METHODS: This article focuses on a combination of clinical modalities that integrate osteopathic cross-fiber massage, microcurrent electroacupuncture, far-infrared heat, and photobiomodulation to break up the scar tissue and reactivate the body's intrinsic re …
MATERIALS AND METHODS: This article focuses on a combination of clinical modalities that integrate osteopathic cross-fiber massage, microcur …
Transcutaneous systemic photobiomodulation reduced lung inflammation in experimental model of asthma by altering the mast cell degranulation and interleukin 10 level.
Alonso PT, Schapochnik A, Klein S, Brochetti R, Damazo AS, de Souza Setubal Destro MF, Lino-Dos-Santos-Franco A. Alonso PT, et al. Lasers Med Sci. 2022 Mar;37(2):1101-1109. doi: 10.1007/s10103-021-03359-1. Epub 2021 Jun 19. Lasers Med Sci. 2022. PMID: 34146193
Its treatment includes several drugs, high cost, and considerable side effects. Photobiomodulation (PBM) emerges as an alternative treatment, showing good results, and it can be applied locally or systemically. Here, we aim to evaluate the effect of transcutaneous systemic …
Its treatment includes several drugs, high cost, and considerable side effects. Photobiomodulation (PBM) emerges as an alternative tr …
The Effectiveness of Photobiomodulation on Accelerating Tooth Movement in Orthodontics: A Systematic Review and Meta-Analysis.
Li J, Ge X, Guan H, Jia L, Chang W, Ma W. Li J, et al. Photobiomodul Photomed Laser Surg. 2021 Apr;39(4):232-244. doi: 10.1089/photob.2020.4954. Epub 2021 Mar 17. Photobiomodul Photomed Laser Surg. 2021. PMID: 33733872
Objective: This meta-analysis evaluated the effectiveness of photobiomodulation therapy (PBMT) on accelerating orthodontic tooth movement (OTM) in clinical practice. ...Conclusions: There is insufficient evidence to support that photobiomodulation accelerates tooth …
Objective: This meta-analysis evaluated the effectiveness of photobiomodulation therapy (PBMT) on accelerating orthodontic tooth move …
Therapeutic Potential of Photobiomodulation In Alzheimer's Disease: A Systematic Review.
Cardoso FDS, Lopes Martins RÁB, Gomes da Silva S. Cardoso FDS, et al. J Lasers Med Sci. 2020 Fall;11(Suppl 1):S16-S22. doi: 10.34172/jlms.2020.S3. Epub 2020 Dec 30. J Lasers Med Sci. 2020. PMID: 33995964 Free PMC article. Review.
Scientific society has proposed some non-pharmacological interventions, among which photobiomodulation has gained prominence for its beneficial effects. Therefore, we investigated, through systematic review, the therapeutic potential of photobiomodulation in AD. ... …
Scientific society has proposed some non-pharmacological interventions, among which photobiomodulation has gained prominence for its …
Effects of Photobiomodulation on Changes in Cognitive Function and Regional Cerebral Blood Flow in Patients with Mild Cognitive Impairment: A Pilot Uncontrolled Trial.
Baik JS, Lee TY, Kim NG, Pak K, Ko SH, Min JH, Shin YI. Baik JS, et al. J Alzheimers Dis. 2021;83(4):1513-1519. doi: 10.3233/JAD-210386. J Alzheimers Dis. 2021. PMID: 34420956 Clinical Trial.
BACKGROUND: Photobiomodulation (PBM) affects local blood flow regulation through nitric oxide generation, and various studies have reported on its effect on improving cognitive function in neurodegenerative diseases. ...
BACKGROUND: Photobiomodulation (PBM) affects local blood flow regulation through nitric oxide generation, and various studies have re …
Could Photobiomodulation Treat Autism Spectrum Disorder?
Hamblin MR. Hamblin MR. Photobiomodul Photomed Laser Surg. 2022 Jun;40(6):367-369. doi: 10.1089/photob.2022.0051. Epub 2022 May 25. Photobiomodul Photomed Laser Surg. 2022. PMID: 35613405 No abstract available.
Effect of Photobiomodulation on the Incidence of Alveolar Osteitis and Postoperative Pain following Mandibular Third Molar Surgery: A Double-Blind Randomized Clinical Trial.
Nejat AH, Eshghpour M, Danaeifar N, Abrishami M, Vahdatinia F, Fekrazad R. Nejat AH, et al. Photochem Photobiol. 2021 Sep;97(5):1129-1135. doi: 10.1111/php.13457. Epub 2021 Jun 17. Photochem Photobiol. 2021. PMID: 34048061 Clinical Trial.
The current study aimed to evaluate the effectiveness of photobiomodulation therapy for the prevention of incidence of alveolar osteitis (AO) and postoperative pain following third molar surgery. ...According to the findings of this study, photobiomodulation therapy …
The current study aimed to evaluate the effectiveness of photobiomodulation therapy for the prevention of incidence of alveolar ostei …
Treatment of partial injury of the calcaneus tendon with heterologous fibrin biopolymer and/or photobiomodulation in rats.
de Freitas Dutra Júnior E, Hidd SMCM, Amaral MM, Filho ALMM, Assis L, Ferreira RS Jr, Barraviera B, Martignago CCS, Figueredo-Silva J, de Oliveira RA, Tim CR. de Freitas Dutra Júnior E, et al. Lasers Med Sci. 2022 Mar;37(2):971-981. doi: 10.1007/s10103-021-03341-x. Epub 2021 May 26. Lasers Med Sci. 2022. PMID: 34041619 Clinical Trial.
The present study aimed to evaluate the new heterologous fibrin biopolymer associated, or not, with photobiomodulation therapy for application in tendon injuries, considered a serious and common orthopedic problem. Thus, 84 Rattus norvegicus had partial transection of the …
The present study aimed to evaluate the new heterologous fibrin biopolymer associated, or not, with photobiomodulation therapy for ap …
An Effective and Safe Novel Treatment of Opioid Use Disorder: Unilateral Transcranial Photobiomodulation.
Schiffer F, Khan A, Bolger E, Flynn E, Seltzer WP, Teicher MH. Schiffer F, et al. Front Psychiatry. 2021 Aug 10;12:713686. doi: 10.3389/fpsyt.2021.713686. eCollection 2021. Front Psychiatry. 2021. PMID: 34447323 Free PMC article.
We report here our findings from our second randomized controlled trial to evaluate unilateral transcranial photobiomodulation as a treatment for opioid use disorder. Methods: We enrolled 39 participants with active opioid cravings at 2 sites, 19 received the active treatm …
We report here our findings from our second randomized controlled trial to evaluate unilateral transcranial photobiomodulation as a t …
Laterally closed tunnel technique with and without adjunctive photobiomodulation therapy for the management of isolated gingival recession-a randomized controlled assessor-blinded clinical trial.
Lavu V, Gutknecht N, Vasudevan A, S K B, Hilgers RD, Franzen R. Lavu V, et al. Lasers Med Sci. 2022 Apr;37(3):1625-1634. doi: 10.1007/s10103-021-03411-0. Epub 2021 Sep 20. Lasers Med Sci. 2022. PMID: 34545437 Free PMC article. Clinical Trial.

The VAS scores were significantly lower for the test (laterally closed tunnel technique + photobiomodulation) group as compared to control (laterally closed tunnel technique + sham laser) over time (p = < 0.0001) as well as per site (p = 0.0006) The Early Wound Healing

The VAS scores were significantly lower for the test (laterally closed tunnel technique + photobiomodulation) group as compared to co …
Transcranial photobiomodulation (808 nm) attenuates pentylenetetrazole-induced seizures by suppressing hippocampal neuroinflammation, astrogliosis, and microgliosis in peripubertal rats.
Tsai CM, Chang SF, Li CC, Chang H. Tsai CM, et al. Neurophotonics. 2022 Jan;9(1):015006. doi: 10.1117/1.NPh.9.1.015006. Epub 2022 Mar 25. Neurophotonics. 2022. PMID: 35345494 Free PMC article.
Significance: Transcranial photobiomodulation (tPBM) at 808 nm attenuates pentylenetetrazole (PTZ)-induced seizures and convulsive status epilepticus (CSE) in peripubertal rats by protecting neurons from injury and parvalbumin-positive interneurons from apoptosis, and pres …
Significance: Transcranial photobiomodulation (tPBM) at 808 nm attenuates pentylenetetrazole (PTZ)-induced seizures and convulsive st …
Photobiomodulation Therapy in Veterinary Medicine: A Review.
Hochman L. Hochman L. Top Companion Anim Med. 2018 Sep;33(3):83-88. doi: 10.1053/j.tcam.2018.06.004. Epub 2018 Jul 5. Top Companion Anim Med. 2018. PMID: 30243364 Review.
Laser therapy, or photobiomodulation, has rapidly grown in popularity in human and veterinary medicine. ...
Laser therapy, or photobiomodulation, has rapidly grown in popularity in human and veterinary medicine. ...
Photobiomodulation of wound healing via visible and infrared laser irradiation.
Solmaz H, Ulgen Y, Gulsoy M. Solmaz H, et al. Lasers Med Sci. 2017 May;32(4):903-910. doi: 10.1007/s10103-017-2191-0. Epub 2017 Mar 20. Lasers Med Sci. 2017. PMID: 28321647
Fibroblast cells are known to be one of the key elements in wound healing process, which has been under the scope of research for decades. However, the exact mechanism of photobiomodulation on wound healing is not fully understood yet. Photobiomodulation of 635 and …
Fibroblast cells are known to be one of the key elements in wound healing process, which has been under the scope of research for decades. H …
Effect of photobiomodulation on the severity of oral mucositis and molecular changes in head and neck cancer patients undergoing radiotherapy: a study protocol for a cost-effectiveness randomized clinical trial.
Martins AFL, Nogueira TE, Morais MO, Oton-Leite AF, Valadares MC, Batista AC, Freitas NMA, Leles CR, Mendonça EF. Martins AFL, et al. Trials. 2019 Feb 1;20(1):97. doi: 10.1186/s13063-019-3196-8. Trials. 2019. PMID: 30709370 Free PMC article.
The study will be conducted according to the Brazilian public health system perspective. DISCUSSION: Photobiomodulation is an effective therapy that reduces the cost associated with OM treatment. ...Therefore, this study widens the knowledge about the safety of and strengt …
The study will be conducted according to the Brazilian public health system perspective. DISCUSSION: Photobiomodulation is an effecti …
Enhancement of Frequency-Specific Hemodynamic Power and Functional Connectivity by Transcranial Photobiomodulation in Healthy Humans.
Truong NCD, Wang X, Wanniarachchi H, Liu H. Truong NCD, et al. Front Neurosci. 2022 Jun 10;16:896502. doi: 10.3389/fnins.2022.896502. eCollection 2022. Front Neurosci. 2022. PMID: 35757526 Free PMC article.
Transcranial photobiomodulation (tPBM) has been considered a safe and effective brain stimulation modality being able to enhance cerebral oxygenation and neurocognitive function. ...
Transcranial photobiomodulation (tPBM) has been considered a safe and effective brain stimulation modality being able to enhance cere …
Effects of Chronic Photobiomodulation with Transcranial Near-Infrared Laser on Brain Metabolomics of Young and Aged Rats.
Dos Santos Cardoso F, Dos Santos JCC, Gonzalez-Lima F, Araújo BHS, Lopes-Martins RÁB, Gomes da Silva S. Dos Santos Cardoso F, et al. Mol Neurobiol. 2021 May;58(5):2256-2268. doi: 10.1007/s12035-020-02247-z. Epub 2021 Jan 8. Mol Neurobiol. 2021. PMID: 33417219
Since laser photobiomodulation has been found to enhance brain energy metabolism and cognition, we conducted the first metabolomics study to systematically analyze the metabolites modified by brain photobiomodulation. ...Statistical analyses of the brain metabolomic …
Since laser photobiomodulation has been found to enhance brain energy metabolism and cognition, we conducted the first metabolomics s …
Photobiomodulation Therapy to Mitigate Radiation Fibrosis Syndrome.
Tam M, Arany PR, Robijns J, Vasconcelos R, Corby P, Hu K. Tam M, et al. Photobiomodul Photomed Laser Surg. 2020 Jun;38(6):355-363. doi: 10.1089/photob.2019.4766. Epub 2020 May 27. Photobiomodul Photomed Laser Surg. 2020. PMID: 32460618 Review.
Objective: We evaluated the role of photobiomodulation (PBM) in radiation fibrosis syndrome (RFS). Background: Radiation therapy (RT) is an important treatment utilized in over half of newly diagnosed cancers. ...With improved oncologic outcomes and survival for cancer pat …
Objective: We evaluated the role of photobiomodulation (PBM) in radiation fibrosis syndrome (RFS). Background: Radiation therapy (RT) …
Photobiomodulation therapy for male infertility.
Zupin L, Pascolo L, Luppi S, Ottaviani G, Crovella S, Ricci G. Zupin L, et al. Lasers Med Sci. 2020 Oct;35(8):1671-1680. doi: 10.1007/s10103-020-03042-x. Epub 2020 Jun 1. Lasers Med Sci. 2020. PMID: 32483749 Review.
Moreover, in the recent years, an increased number of patients have required to freeze their gametes in order to preserve their fertility. Photobiomodulation (PBM) therapy is a potential treatment that has been used for different clinical application basically aimed at bio …
Moreover, in the recent years, an increased number of patients have required to freeze their gametes in order to preserve their fertility. …
Effect of photobiomodulation treatment in the sublingual, radial artery region, and along the spinal column in individuals with multiple sclerosis: Protocol for a randomized, controlled, double-blind, clinical trial.
da Silva T, da Silva FC, Gomes AO, Viana AO, Gonçalves MLL, Rodrigues MFSD, Horliana ACRT, da Silva DFT, Chavantes MC, Fragoso YD, Branco LP, Motta LJ, Fernandes KPS, Mesquita-Ferrari RA, Bussadori SK. da Silva T, et al. Medicine (Baltimore). 2018 May;97(19):e0627. doi: 10.1097/MD.0000000000010627. Medicine (Baltimore). 2018. PMID: 29742699 Free PMC article. Clinical Trial.
The patients will be divided into 6 groups. Groups 1 and 2 will receive sham and active photobiomodulation in the sublingual region, respectively. Groups 3 and 4 will receive sham and active photobiomodulation along the spinal cord, respectively. Group 5 will receiv …
The patients will be divided into 6 groups. Groups 1 and 2 will receive sham and active photobiomodulation in the sublingual region, …
The impact of photobiomodulation on osteoblast-like cell: a review.
Deana AM, de Souza AM, Teixeira VP, Mesquita-Ferrari RA, Bussadori SK, Fernandes KPS. Deana AM, et al. Lasers Med Sci. 2018 Jul;33(5):1147-1158. doi: 10.1007/s10103-018-2486-9. Epub 2018 Mar 23. Lasers Med Sci. 2018. PMID: 29572767 Review.
Moreover, a wide variety of experimental models were used to experimentally analyze the impact of photobiomodulation, the most common of which were alkaline phosphatase, MTT, and cell count. This review suggests that osteoblastic-like cells are susceptible to photobiomo
Moreover, a wide variety of experimental models were used to experimentally analyze the impact of photobiomodulation, the most common …
Effects of LED photobiomodulation therapy on the subcutaneous fatty tissue of obese individuals - histological and immunohistochemical analysis.
Modena DAO, Soares CD, Martignago CCS, Almeida S, Cazzo E, Chaim EA. Modena DAO, et al. J Cosmet Laser Ther. 2022 Nov 17;24(6-8):84-90. doi: 10.1080/14764172.2022.2109677. Epub 2022 Sep 8. J Cosmet Laser Ther. 2022. PMID: 36074934
Photobiomodulation therapy (PBMT) has become an adjuvant therapeutic possibility in body remodeling procedures. ...
Photobiomodulation therapy (PBMT) has become an adjuvant therapeutic possibility in body remodeling procedures. ...
Applications of photobiomodulation in hearing research: from bench to clinic.
Lee JH, Kim S, Jung JY, Lee MY. Lee JH, et al. Biomed Eng Lett. 2019 Jun 18;9(3):351-358. doi: 10.1007/s13534-019-00114-y. eCollection 2019 Aug. Biomed Eng Lett. 2019. PMID: 31456894 Free PMC article. Review.
No accepted therapeutic modality for sensorineural hearing loss is yet available; most clinicians emphasize rehabilitation, placing hearing aids and cochlear implants. Photobiomodulation (PBM) employs light energy to enhance or modulate the activities of specific organs, a …
No accepted therapeutic modality for sensorineural hearing loss is yet available; most clinicians emphasize rehabilitation, placing hearing …
Photobiomodulation Therapy Improves Spermatogenesis in Busulfan-Induced Infertile Mouse.
Rezaei F, Bayat M, Nazarian H, Aliaghaei A, Abaszadeh HA, Naserzadeh P, Amini A, Ebrahimi V, Abdi S, Abdollahifar MA. Rezaei F, et al. Reprod Sci. 2021 Oct;28(10):2789-2798. doi: 10.1007/s43032-021-00557-8. Epub 2021 Apr 6. Reprod Sci. 2021. PMID: 33825170
About 50% of infertility is caused by men. This study aimed to investigate the efficiency of photobiomodulation on spermatogenesis in a busulfan-induced infertile mouse as a testicular degeneration treatment. ...In the study, azoospermia was induced by busulfan as a testic …
About 50% of infertility is caused by men. This study aimed to investigate the efficiency of photobiomodulation on spermatogenesis in …
Photobiomodulation Effectiveness in Treating Androgenetic Alopecia.
Scarpim AC, Baptista A, Magalhães DSF, Nunez SC, Navarro RS, Frade-Barros AF. Scarpim AC, et al. Photobiomodul Photomed Laser Surg. 2022 Jun;40(6):387-394. doi: 10.1089/photob.2022.0011. Photobiomodul Photomed Laser Surg. 2022. PMID: 35749704
Objective: The aim of the study was to evaluate the effects of photobiomodulation (PBM) in patients with AGA. Methods: Twenty-five men 20-54 years of age participated in this study. ...
Objective: The aim of the study was to evaluate the effects of photobiomodulation (PBM) in patients with AGA. Methods: Twenty-five me …
[Transcranial photobiomodulation in therapy of neurodegenerative diseases of the brain: theoretical background and clinical effectiveness].
Belova AN, Israelyan YA, Sushin VO, Shabanova MA, Rezenova AM. Belova AN, et al. Vopr Kurortol Fizioter Lech Fiz Kult. 2021;98(6):61-67. doi: 10.17116/kurort20219806161. Vopr Kurortol Fizioter Lech Fiz Kult. 2021. PMID: 34965698 Russian.
Transcranial photobiomodulation (tPBM) is a form of light therapy that uses monochromatic visible and infrared light from non-ionizing radiation sources (lasers, LEDs) placed on the scalp, forehead, or intranasally to project light directly to target areas of the brain. .. …
Transcranial photobiomodulation (tPBM) is a form of light therapy that uses monochromatic visible and infrared light from non-ionizin …
Photobiomodulation with simultaneous use of red and infrared light emitting diodes in the treatment of temporomandibular disorder: study protocol for a randomized, controlled and double-blind clinical trial.
Sousa DFM, Gonçalves MLL, Politti F, Lovisetto RDP, Fernandes KPS, Bussadori SK, Mesquita-Ferrari RA. Sousa DFM, et al. Medicine (Baltimore). 2019 Feb;98(6):e14391. doi: 10.1097/MD.0000000000014391. Medicine (Baltimore). 2019. PMID: 30732181 Free PMC article.
Due to its complexity there are already treatments using various forms of therapy. Photobiomodulation using light sources, such as low-level laser or light emitting diodes (LED), with different wavelengths, in a single or combined form, allows one more therapeutic resource …
Due to its complexity there are already treatments using various forms of therapy. Photobiomodulation using light sources, such as lo …
Immediate effects of red (660 nm) and infrared (808 nm) photobiomodulation therapy on fatigue of the orbicularis oris muscle: a randomized clinical study.
Batista MR, Estrela LA, Alves VMN, Motta AR, Furlan RMMM. Batista MR, et al. Codas. 2021 Oct 22;34(2):e20200363. doi: 10.1590/2317-1782/20212020363. eCollection 2021. Codas. 2021. PMID: 34705999 Free PMC article. Clinical Trial.
PURPOSE: To compare the immediate effects of laser photobiomodulation at wavelengths of 660 nm and 808 nm on fatigue of the orbicularis oris. ...The participants were divided into four groups. Group RG received photobiomodulation with a laser wavelength of 660 nm at …
PURPOSE: To compare the immediate effects of laser photobiomodulation at wavelengths of 660 nm and 808 nm on fatigue of the orbicular …
Photobiomodulation enhances facial nerve regeneration via activation of PI3K/Akt signaling pathway-mediated antioxidant response.
Li B, Wang X. Li B, et al. Lasers Med Sci. 2022 Mar;37(2):993-1006. doi: 10.1007/s10103-021-03344-8. Epub 2021 Jul 24. Lasers Med Sci. 2022. PMID: 34302577 Free PMC article.
Various parameters of photobiomodulation were assigned to the facial nerves and Schwann cells (SCs) separately during crushed injury in rats. ...These findings provide clear experimental evidence of photobiomodulation as an alternative therapeutic strategy for perip …
Various parameters of photobiomodulation were assigned to the facial nerves and Schwann cells (SCs) separately during crushed injury …
EEG-Validated Photobiomodulation Treatment of Dementia-Case Study.
Vrankic M, Vlahinić S, Šverko Z, Markovinović I. Vrankic M, et al. Sensors (Basel). 2022 Oct 5;22(19):7555. doi: 10.3390/s22197555. Sensors (Basel). 2022. PMID: 36236654 Free PMC article.
In this article, we perform a case study of the impact of photobiomodulation (PBM) on brain power spectrum and connectivity in an elderly person with a Self Administered Gerocognitive Exam (SAGE) score indicating probable memory and thinking disorder. ...
In this article, we perform a case study of the impact of photobiomodulation (PBM) on brain power spectrum and connectivity in an eld …
Photobiomodulation is effective in oral lichen planus: A randomized, controlled, double-blind study.
Ferri EP, Cunha KRL, Abboud CS, de Barros Gallo C, de Sousa Sobral S, de Fatima Teixeira da Silva D, Horliana ACRT, Franco AL, Rodrigues MFSD. Ferri EP, et al. Oral Dis. 2021 Jul;27(5):1205-1216. doi: 10.1111/odi.13662. Epub 2020 Oct 26. Oral Dis. 2021. PMID: 33012017 Clinical Trial.
Both the Control and photobiomodulation groups presented similar clinical resolution and recurrence rates. ...Moreover, photobiomodulation is a safe and non-invasive therapy with the remarkable advantage of no adverse effects....
Both the Control and photobiomodulation groups presented similar clinical resolution and recurrence rates. ...Moreover, photobiomo
The Effect of Photobiomodulation on Human Mesenchymal Cells: A Literature Review.
Pinto H, Goñi Oliver P, Sánchez-Vizcaíno Mengual E. Pinto H, et al. Aesthetic Plast Surg. 2021 Aug;45(4):1826-1842. doi: 10.1007/s00266-021-02173-y. Epub 2021 Feb 22. Aesthetic Plast Surg. 2021. PMID: 33616715 Review.
A review of the published articles on human conditioned-by-photobiomodulation mesenchymal cells in an in vitro set up was carried out. ...METHODS: A search in English of the PubMed database was carried out with the search criteria: photobiomodulation or photoactivat …
A review of the published articles on human conditioned-by-photobiomodulation mesenchymal cells in an in vitro set up was carried out …
Intraoral photobiomodulation diminishes pain and improves functioning in women with temporomandibular disorder: a randomized, sham-controlled, double-blind clinical trial : Intraoral photobiomodulation diminishes pain in women with temporomandibular disorder.
Herpich CM, Leal-Junior ECP, Politti F, de Paula Gomes CAF, Dos Santos Glória IP, de Souza Amaral MFR, Herpich G, de Azevedo LMA, de Oliveira Gonzalez T, Biasotto-Gonzalez DA. Herpich CM, et al. Lasers Med Sci. 2020 Mar;35(2):439-445. doi: 10.1007/s10103-019-02841-1. Epub 2019 Jul 19. Lasers Med Sci. 2020. PMID: 31325122 Clinical Trial.
The participants were randomly allocated to two groups (active and sham photobiomodulation). The evaluations involved this use of the visual analog scale, digital calipers, and a functional scale. Photobiomodulation was administered intraorally in the region of the …
The participants were randomly allocated to two groups (active and sham photobiomodulation). The evaluations involved this use of the …
Lights on for Autism: Exploring Photobiomodulation as an Effective Therapeutic Option.
Hamilton C, Liebert A, Pang V, Magistretti P, Mitrofanis J. Hamilton C, et al. Neurol Int. 2022 Oct 27;14(4):884-893. doi: 10.3390/neurolint14040071. Neurol Int. 2022. PMID: 36412693 Free PMC article. Review.
In this mini-review, we consider the effectiveness of a potential new treatment for autism, known as photobiomodulation, the therapeutic use of red to near infrared light on body tissues. This treatment has been shown in a range of pathological conditions-to improve the ke …
In this mini-review, we consider the effectiveness of a potential new treatment for autism, known as photobiomodulation, the therapeu …
Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives.
Hamblin MR. Hamblin MR. Clin Cosmet Investig Dermatol. 2019 Sep 6;12:669-678. doi: 10.2147/CCID.S184979. eCollection 2019. Clin Cosmet Investig Dermatol. 2019. PMID: 31686888 Free PMC article.
Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. ...
Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hai
Effect of Photobiomodulation in Lipopolysaccharide-Treated Myoblasts.
Victor EC, Goulardins J, Cardoso VO, Silva REC, Brugnera A, Bussadori SK, Fernandes KPS, Mesquita-Ferrari RA. Victor EC, et al. Photobiomodul Photomed Laser Surg. 2021 Jan;39(1):30-37. doi: 10.1089/photob.2019.4782. Epub 2020 Dec 17. Photobiomodul Photomed Laser Surg. 2021. PMID: 33332202
Objective: To evaluate the effect of photobiomodulation (PBM) on cell viability, synthesis of nitric oxide (NO), and interleukin (IL)-6 inflammatory cytokine production in myoblasts cultured in the presence of lipopolysaccharides (LPSs). ...
Objective: To evaluate the effect of photobiomodulation (PBM) on cell viability, synthesis of nitric oxide (NO), and interleukin (IL) …
Effect of Photobiomodulation on Atrophic-Erosive Clinical Forms of Oral Lichen Planus: A Systematic Review.
Ruiz Roca JA, López Jornet P, Gómez García FJ, Marcos Aroca P. Ruiz Roca JA, et al. Dent J (Basel). 2022 Nov 27;10(12):221. doi: 10.3390/dj10120221. Dent J (Basel). 2022. PMID: 36547037 Free PMC article. Review.
For this reason, there are different treatments that improve the associated signs and symptoms. One of these therapies is photobiomodulation (PBM), which, although new, has a high level of acceptance in dentistry based on evidence. ...MATERIAL AND METHODS: The databases Pu …
For this reason, there are different treatments that improve the associated signs and symptoms. One of these therapies is photobiomodulat
Photobiomodulation prevents DNA fragmentation of alveolar epithelial cells and alters the mRNA levels of caspase 3 and Bcl-2 genes in acute lung injury.
Sergio LPDS , Thomé AMC , Trajano LADSN , Mencalha AL , da Fonseca AS , de Paoli F . Sergio LPDS , et al. Photochem Photobiol Sci. 2018 Jul 11;17(7):975-983. doi: 10.1039/c8pp00109j. Photochem Photobiol Sci. 2018. PMID: 29922788
Thus, the aim of this study was to evaluate the mRNA levels from caspase-3 and BCL-2 genes and DNA fragmentation in lung tissue from Wistar rats affected by ALI and subjected to photobiomodulation by exposure to a low power infrared laser (808 nm; 100 mW; 3.571 W cm-2; fou …
Thus, the aim of this study was to evaluate the mRNA levels from caspase-3 and BCL-2 genes and DNA fragmentation in lung tissue from Wistar …
The Optimal Energy Density of Photobiomodulation Therapy in Decreasing Orthodontic-Related Pain: A Systematic Review and Network Meta-Analysis.
Zhi C, Wang T, Guo Z, Liu D, Duan X, Yu X, Zhang C. Zhi C, et al. Photobiomodul Photomed Laser Surg. 2021 Oct;39(10):642-653. doi: 10.1089/photob.2021.0071. Photobiomodul Photomed Laser Surg. 2021. PMID: 34662524
Objective: The aim of this network meta-analysis (NMA) was to explore the optimal energy density (ED) for relief of orthodontic-related pain by photobiomodulation therapy. Background: Orthodontic treatment corrects the deformity of teeth, dental arch, jaw, and face using v …
Objective: The aim of this network meta-analysis (NMA) was to explore the optimal energy density (ED) for relief of orthodontic-related pain …
Photobiomodulation for Alzheimer's Disease: Translating Basic Research to Clinical Application.
Enengl J, Hamblin MR, Dungel P. Enengl J, et al. J Alzheimers Dis. 2020;75(4):1073-1082. doi: 10.3233/JAD-191210. J Alzheimers Dis. 2020. PMID: 32390621 Free PMC article. Review.
One of the challenges in translating new therapeutic approaches to the patient bedside lies in bridging the gap between scientists who are conducting basic laboratory research and medical practitioners who are not exposed to highly specialized journals. This review covers the lit …
One of the challenges in translating new therapeutic approaches to the patient bedside lies in bridging the gap between scientists who are c …
Wound Photobiomodulation Treatment Outcomes in Animal Models.
Lopez A, Brundage C. Lopez A, et al. J Vet Med. 2019 Jul 28;2019:6320515. doi: 10.1155/2019/6320515. eCollection 2019. J Vet Med. 2019. PMID: 31467931 Free PMC article. Review.
The possibilities that photobiomodulation has brought on to the medical field are ever expanding and the scope it has reached is infinite. ...Further research involving LLLT studies that focus on different factors including health status, treatment interval, wavelength, an …
The possibilities that photobiomodulation has brought on to the medical field are ever expanding and the scope it has reached is infi …
Photobiomodulation for the Treatment of Primary Headache: Systematic Review of Randomized Clinical Trials.
Gomes AO, Martimbianco ALC, Brugnera Junior A, Horliana ACRT, da Silva T, Santos EM, Fragoso YD, Fernandes KPS, Nammour S, Bussadori SK. Gomes AO, et al. Life (Basel). 2022 Jan 11;12(1):98. doi: 10.3390/life12010098. Life (Basel). 2022. PMID: 35054491 Free PMC article. Review.
The purpose of this study was to evaluate the efficacy and safety of photobiomodulation as an adjuvant treatment for primary headache. A systematic review of randomized clinical trials was performed. ...Most of the included studies had an overall high risk of bias. Compare …
The purpose of this study was to evaluate the efficacy and safety of photobiomodulation as an adjuvant treatment for primary headache …
Mechanistic aspects of photobiomodulation therapy in the nervous system.
Ramezani F, Neshasteh-Riz A, Ghadaksaz A, Fazeli SM, Janzadeh A, Hamblin MR. Ramezani F, et al. Lasers Med Sci. 2022 Feb;37(1):11-18. doi: 10.1007/s10103-021-03277-2. Epub 2021 Feb 24. Lasers Med Sci. 2022. PMID: 33624187 Review.
Photobiomodulation therapy (PBMT) previously known as low-level laser therapy (LLLT) has been used for over 30 years, to treat neurological diseases. ...
Photobiomodulation therapy (PBMT) previously known as low-level laser therapy (LLLT) has been used for over 30 years, to treat neurol
Transcranial Photobiomodulation For The Management Of Depression: Current Perspectives.
Askalsky P, Iosifescu DV. Askalsky P, et al. Neuropsychiatr Dis Treat. 2019 Nov 22;15:3255-3272. doi: 10.2147/NDT.S188906. eCollection 2019. Neuropsychiatr Dis Treat. 2019. PMID: 31819453 Free PMC article. Review.
In this paper, we review a novel neuromodulation strategy, transcranial photobiomodulation (t-PBM) with near-infrared light (NIR). The scope of our review includes the known biological mechanisms of t-PBM, as well as its efficacy in animal models of depression and in patie …
In this paper, we review a novel neuromodulation strategy, transcranial photobiomodulation (t-PBM) with near-infrared light (NIR). Th …
Unilateral transcranial photobiomodulation for opioid addiction in a clinical practice: A clinical overview and case series.
Schiffer F. Schiffer F. J Psychiatr Res. 2021 Jan;133:134-141. doi: 10.1016/j.jpsychires.2020.12.004. Epub 2020 Dec 3. J Psychiatr Res. 2021. PMID: 33340792 Free article.
Two are typical of very positively responsive patients, one is of a positively but not remarkably responsive patient, and one of a non-responsive patient. The author used unilateral transcranial photobiomodulation (UtPBM), near infrared mode, applied to the hemisphere with …
Two are typical of very positively responsive patients, one is of a positively but not remarkably responsive patient, and one of a non-respo …
Progress in Photobiomodulation for Bone Fractures: A Narrative Review.
Cheng W, Yao M, Sun K, Li W. Cheng W, et al. Photobiomodul Photomed Laser Surg. 2020 May;38(5):260-271. doi: 10.1089/photob.2019.4732. Photobiomodul Photomed Laser Surg. 2020. PMID: 32427551 Review.
Objective: The aim of this article is to examine current concepts and the future direction of implementing photobiomodulation (PBM) for fracture treatment. Background data: The effectiveness of PBM for bone regeneration has been demonstrated throughout in vitro studies and …
Objective: The aim of this article is to examine current concepts and the future direction of implementing photobiomodulation (PBM) f …