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1993 1
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122 results

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Page 1
Improved survival at the population level for patients with advanced Merkel cell carcinoma following availability of immunotherapy.
Paulson KG, Park SY, Bhatia S, Hippe DS, Nghiem P. Paulson KG, et al. Among authors: bhatia s. J Am Acad Dermatol. 2025 Mar 10:S0190-9622(25)00422-0. doi: 10.1016/j.jaad.2025.03.006. Online ahead of print. J Am Acad Dermatol. 2025. PMID: 40074150
BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer with poor survival rates. Immune checkpoint inhibitors (ICIs) were Food and Drug Administration-approved for advanced MCC in 2017, but their real-world survival impact remains unclear. ...
BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer with poor survival rates. Immune checkpoint inhibitors (ICIs) we …
Adjuvant Proton Beam Radiation Therapy for Sinonasal Mucosal Melanoma.
Takayesu JSK, Parvathaneni U, Laramore GE, Panjwani N, Sillings J, Futran ND, Humphreys IM, Jafari A, Abuzeid WM, Barber B, Marchiano E, Lee SM, Thompson JA, Hall E, Bhatia S, Rodriguez CP, Liao JJ. Takayesu JSK, et al. Among authors: bhatia s, thompson ja. Cancer Rep (Hoboken). 2025 Feb;8(2):e70111. doi: 10.1002/cnr2.70111. Cancer Rep (Hoboken). 2025. PMID: 39907094 Free PMC article.
BACKGROUND: Head and neck mucosal melanoma (HNMM) is rare and carries a poor prognosis with high rates of disease progression. ...
BACKGROUND: Head and neck mucosal melanoma (HNMM) is rare and carries a poor prognosis with high rates of disease progression. ...
Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study.
Bhatia S, Topalian SL, Sharfman W, Meyer T, Steven N, Lao CD, Fariñas-Madrid L, Devriese LA, Moore K, Ferris RL, Honma Y, Elias I, Srirangam A, Garnett-Benson C, Lee M, Nghiem P. Bhatia S, et al. J Clin Oncol. 2025 Mar 20;43(9):1137-1147. doi: 10.1200/JCO-24-02138. Epub 2025 Jan 31. J Clin Oncol. 2025. PMID: 39889250 Free PMC article. Clinical Trial.
PURPOSE: Approximately 50% of patients with advanced Merkel cell carcinoma (MCC) have primary or acquired resistance to PD-(L)1 blockade, which may be overcome using combination immune checkpoint inhibition (ICI) with anti-cytotoxic T lymphocyte antigen-4 antibody. ...
PURPOSE: Approximately 50% of patients with advanced Merkel cell carcinoma (MCC) have primary or acquired resistance to PD-(L)1 block …
Combined programmed cell death protein 1 and cytotoxic T-lymphocyte associated protein 4 blockade in an international cohort of patients with acral lentiginous melanoma.
McGillivray E, Ashouri K, Chatziioannou E, Gallegos JAO, Zarka J, Kechter J, Hwang AS, Zhang K, Barros M, Yeh J, Okazaki I, Crocker AB, Maeda T, Park SJ, Choi J, Andreoli M, Darwish T, Savage DJ, Kim KB, Gupta J, Shen J, Shirai K, Choi A, Pai L, Vazquez VL, Moser J, Amaral T, Hernandez Aya LF, Lutzky J, Najjar YG, Costello CM, Mangold AR, Bhatia S, Gibney GT, Farma JM, Daniels GA, Sosman J, Chandra S, Mangla A, Bollin K, Possik PA, Robles-Espinoza CD, Ito F, In GK. McGillivray E, et al. Among authors: bhatia s. Br J Dermatol. 2025 Jan 24;192(2):316-326. doi: 10.1093/bjd/ljae401. Br J Dermatol. 2025. PMID: 39438074
Acral lentiginous melanoma (or 'ALM' for short) is rare type of melanoma that appears on the palms of the hands, soles of the feet or in nailbeds. Unusually, it is not thought to be caused by exposure to the sun, unlike most other skin melanomas. Medications …
Acral lentiginous melanoma (or 'ALM' for short) is rare type of melanoma that appears on the palms of the hands, soles of the …
Intratumoral STING agonist reverses immune evasion in PD-(L)1-refractory Merkel cell carcinoma: mechanistic insights from detailed biomarker analyses.
Pulliam T, Jani S, Goff PH, Bhakuni R, Tabachnick-Cherny S, Smythe K, Seaton BW, Tachiki L, Kulikauskas R, Church C, Koelle DM, Nghiem P, Bhatia S. Pulliam T, et al. Among authors: bhatia s. J Immunother Cancer. 2024 Oct 14;12(10):e009803. doi: 10.1136/jitc-2024-009803. J Immunother Cancer. 2024. PMID: 39401968 Free PMC article.
We report detailed biomarker analyses in a patient with anti-PD-L1 refractory, Merkel cell polyomavirus (MCPyV)-positive, metastatic Merkel cell carcinoma (MCC) who was treated with an intratumoral (IT) STING agonist (ADU-S100) plus intravenous anti-PD-1 antibody (s …
We report detailed biomarker analyses in a patient with anti-PD-L1 refractory, Merkel cell polyomavirus (MCPyV)-positive, metastatic …
Amelanotic Melanoma: A Rare Sinonasal Malignancy.
Apoorva KV, Bhatia S, Shenoy SV, Hegde S, Gowthuvalli C, Aggarwal I. Apoorva KV, et al. Among authors: bhatia s. Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4765-4769. doi: 10.1007/s12070-024-04837-y. Epub 2024 Jun 29. Indian J Otolaryngol Head Neck Surg. 2024. PMID: 39381605
Mucosal melanomas account for less than 1% of all sinonasal malignancies and are aggressive tumours originating from melanocytes in various mucosal epithelia. ...We present a case of a 75-year-old female with epistaxis and nasal blockage, ultimately diagnosed with amelanot …
Mucosal melanomas account for less than 1% of all sinonasal malignancies and are aggressive tumours originating from melanocytes in v …
Biallelic PI4KA Mutations Disrupt B-Cell Metabolism and Cause B-Cell Lymphopenia and Hypogammaglobulinemia.
Saettini F, Guerra F, Mauri M, Salter CG, Adam MP, Adams D, Baple EL, Barredo E, Bhatia S, Borkhardt A, Brusco A, Bugarin C, Chinello C, Crosby AH, D'Souza P, Denti V, Fazio G, Giuliani S, Kuehn HS, Amel H, Elmi A, Lo B, Malighetti F, Mandrile G, Martín-Nalda A, Mefford HC, Moratto D, Emam Mousavi F, Nelson Z, Gutiérrez-Solana LG, Macnamara E, Michaud V, O'Leary M, Pagani L, Pavinato L, Santamaria PV, Planas-Serra L, Quadri M, Raspall-Chaure M, Rebellato S, Rosenzweig SD, Roubertie A, Holzinger D, Deal C, Vockley CW, Savino AM, L Stoddard J, Uhlig HH, Pujol A, Magni F, Paglia G, Cazzaniga G, Piazza R, Barberis M, Biondi A. Saettini F, et al. Among authors: bhatia s. J Clin Immunol. 2024 Sep 23;45(1):15. doi: 10.1007/s10875-024-01793-8. J Clin Immunol. 2024. PMID: 39312004
Merkel cell carcinoma refractory to anti-PD(L)1: utility of adding ipilimumab for salvage therapy.
Akaike T, Jabbour AJ, Goff PH, Park SY, Bhatia S, Nghiem P. Akaike T, et al. Among authors: bhatia s. J Immunother Cancer. 2024 Jul 24;12(7):e009396. doi: 10.1136/jitc-2024-009396. J Immunother Cancer. 2024. PMID: 39053946 Free PMC article. Review.
Merkel cell carcinoma (MCC) incidence has risen to approximately 3,000 cases annually in the USA. ...
Merkel cell carcinoma (MCC) incidence has risen to approximately 3,000 cases annually in the USA. ...
Circulating Tumor DNA Assay Detects Merkel Cell Carcinoma Recurrence, Disease Progression, and Minimal Residual Disease: Surveillance and Prognostic Implications.
Akaike T, Thakuria M, Silk AW, Hippe DS, Park SY, So NA, Maloney NJ, Gunnell L, Eschholz A, Kim EY, Sinha S, Hall ET, Bhatia S, Reddy S, Rodriguez AA, Aleshin A, Choi JS, Tsai KY, Yom SS, Yu SS, Choi J, Chandra S, Nghiem P, Zaba LC. Akaike T, et al. Among authors: bhatia s. J Clin Oncol. 2024 Sep 10;42(26):3151-3161. doi: 10.1200/JCO.23.02054. Epub 2024 Jul 25. J Clin Oncol. 2024. PMID: 39052958 Free PMC article.
PURPOSE: Merkel cell carcinoma (MCC) is an aggressive skin cancer with a 40% recurrence rate, lacking effective prognostic biomarkers and surveillance methods. ...
PURPOSE: Merkel cell carcinoma (MCC) is an aggressive skin cancer with a 40% recurrence rate, lacking effective prognostic biomarkers …
122 results